- Dicarboxylic Acids
- Accession Number
Acyclic acids that contain two carboxyl groups and have the formula HO2C-R-CO2H, where R may be an aromatic or aliphatic group.
Drug Drug Description Succinylcholine A depolarizing skeletal muscle relaxant used adjunctly to anesthesia and for skeletal muscle relaxation during intubation, mechanical ventilation, and surgical procedures. Aliskiren A direct renin inhibitor used to manage hypertension. Artesunate Artesunate is an artemesinin derivative indicated for the initial treatment of severe malaria. Pimelic Acid A group of compounds that are derivatives of heptanedioic acid with the general formula R-C7H11O4. [PubChem] Succinic acid For nutritional supplementation, also for treating dietary shortage or imbalance Citrulline Used for nutritional supplementation, also for treating dietary shortage or imbalance. Succimer A mercaptodicarboxylic acid heavy metal chelator used in the treatment of heavy metal poisoning. Fumaric acid Not Available Bisindolylmaleimide VIII Not Available Malonic acid Not Available Allysine Not Available N-Ethylmaleimide A sulfhydryl reagent that is widely used in experimental biochemical studies. [PubChem] L-2-aminopimelic acid Not Available Glutaric Acid Not Available Mesoxalic acid Not Available 2,6-Diaminopimelic Acid Not Available Bisindolylmaleimide I Not Available Oxalic Acid A strong dicarboxylic acid occurring in many plants and vegetables. It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted... Bis(N-maleimidomethyl)ether Not Available Methylmalonic Acid A malonic acid derivative which is a vital intermediate in the metabolism of fat and protein. Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed... 3-Isopropylmalic Acid Not Available Maleic acid Not Available Meglutol An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as... Guanidinoethylmercaptosuccinic acid Not Available 3-hydroxyglutaric acid Not Available Citraconic acid Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid, or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid. OSI-7904L Investigated for use/treatment in gastric cancer. Edonerpic Investigated for use/treatment in alzheimer's disease. Bevirimat Investigated for use/treatment in HIV infection. Oxogluric acid α-α-Ketoglutarate is not approved for any indication in the world but is an investigational drug in the United States. The potential indications for α-Ketoglutarate are in patients with the metabolic... Dimethyl fumarate A medication used to treat patients with the relapsing-remitting form of multiple sclerosis. Sodium aurothiomalate A disease-modifying antirheumatic drug (DMARD) indicated for the symptomatic treatment of arthritis. Technetium Tc-99m succimer A radioactive diagnostic agent used as an aid in the scintigraphic evaluation of renal parenchymal disorders. L-tartaric acid Tartaric Acid is primarily indicated in conditions like Antiscorbutic, Antiseptic. Calcium citrate An ingredient found in a variety of supplements and vitamins. Iron protein succinylate Not Annotated Ruboxistaurin Ruboxistaurin has been investigated for the basic science of Type 2 Diabetes Mellitus and Type 1 Diabetes Mellitus. LY-2090314 Ly2090314 has been used in trials studying the treatment of Leukemia, Advanced Cancer, and Pancreatic Cancer. Sarpogrelate Sarpogrelate has been investigated for the treatment of Diabetes Mellitus, Diabetic Nephropathy, Coronary Artery Disease, and Renal Insufficiency, Chronic. Malic acid Malic acid has been used in trials studying the treatment of Xerostomia, Depression, and Hypertension. Granotapide Granotapide has been used in trials studying the treatment of Type II Diabetes Mellitus. Bumadizone Bumadizone has been approved for use in Germany and Austria, it is a drug with anti-inflammatory, antipyretic, and analgesic properties, and was marketed for the treatment of both rheumatoid arthritis... Sodium tartrate It acts as an emulsifier and pH control agent in food products , . In the laboratory, it is used while performing the Karl Fischer equation, which is used to... Dimercaptosuccinic acid Not Annotated Monomethyl fumarate Not Annotated Lithium succinate Not Available Albuvirtide Albuvirtide is under investigation in clinical trial NCT03719664 (Albuvirtide and 3BNC117 as Long-Acting Maintenance Therapy in Virologically Suppressed Subjects). Calcium monoethylfumarate Not Annotated Zinc monoethylfumarate Not Annotated Iron (III) oxide adipate Not Annotated Succinylated gelatin A plasma volume expander indicated alone or in combination with blood transfusions.
- Drugs & Drug Targets