Dietary Fats, Unsaturated

Name
Dietary Fats, Unsaturated
Accession Number
DBCAT000295
Description

Unsaturated fats or oils used in foods or as a food.

Drugs
DrugDrug Description
Soybean oilAn oil used as a source of calories and essential fatty acids in selected patients for total parenteral nutrition (TPN) therapy and prevention of essential fatty acid deficiency.
Safflower oilNo approved therapeutic indications.
Omega-3-acid ethyl estersA mixture of fatty acids used as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe hypertriglyceridemia.
Olive oilFor use in adults as a source of calories and fatty acids in total parenteral nutrition [FDA Label]. Sometimes used as an additive in cosmetic products.
Sesame oilSesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices. It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic...
Borage oilBorage oil, or borage seed oil, is a rich source of gamma-linolenic acid (GLA) that is obtained from the seeds of the Borago officinalis (borage). Borage oil is used as...
Evening primrose oilEvening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical...
Omega-3 fatty acidsAn ingredient found in a variety of supplements and vitamins.
Cod liver oilAn ingredient found in a variety of nutritional products.
alpha-Linolenic acidA polyunsaturated omega-3 fatty acid found in many supplements.
IcosapentA polyunsaturated fatty acid, usually found in fish oils, that is used in many supplements.
DoconexentAn omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health.
Icosapent ethylAn ethyl ester of eicosapentaenoic acid (EPA) that reduces synthesis and enhances clearance of triglycerides that is used to treat patients with severe hypertriglyceridemia.
Resolvin E1Resolvin E1 (RX 10001) is under investigation in clinical trial NCT00941018 (Single and Multiple Ascending Oral Dose Study of Resolvin E1 in Healthy Volunteers).
Drugs & Drug Targets
DrugTargetType
Soybean oilPeroxisome proliferator-activated receptor alphatarget
Omega-3-acid ethyl estersSterol O-acyltransferase 1enzyme
Omega-3-acid ethyl estersSterol regulatory element-binding protein 1target
Evening primrose oilElongation of very long chain fatty acids protein 5enzyme
Evening primrose oilFatty acid desaturase 1enzyme
Evening primrose oilFatty acid desaturase 2enzyme
Omega-3 fatty acidsPeroxisome proliferator-activated receptor gammatarget
Omega-3 fatty acidsProstaglandin G/H synthase 2enzyme
Omega-3 fatty acidsArachidonate 5-lipoxygenaseenzyme
Omega-3 fatty acidsPeroxisome proliferator-activated receptor alphatarget
Omega-3 fatty acidsSterol regulatory element-binding protein 1target
alpha-Linolenic acidFatty acid-binding protein, braincarrier
alpha-Linolenic acidFatty acid desaturase 1target
alpha-Linolenic acidFatty acid desaturase 2target
alpha-Linolenic acidSodium/calcium exchanger 1target
alpha-Linolenic acidTransient receptor potential cation channel subfamily V member 1target
alpha-Linolenic acidPeroxisome proliferator-activated receptor alphatarget
alpha-Linolenic acidBile acid receptortarget
alpha-Linolenic acidPeroxisome proliferator-activated receptor deltatarget
alpha-Linolenic acidPeroxisome proliferator-activated receptor gammatarget
alpha-Linolenic acidRetinoic acid receptor RXR-alphatarget
alpha-Linolenic acidElongation of very long chain fatty acids protein 2target
alpha-Linolenic acidElongation of very long chain fatty acids protein 5target
IcosapentProstaglandin G/H synthase 2target
IcosapentProstaglandin G/H synthase 1target
IcosapentFree fatty acid receptor 1target
IcosapentFatty acid desaturase 1target
IcosapentLong-chain-fatty-acid--CoA ligase 4target
IcosapentSodium/calcium exchanger 1target
IcosapentPeroxisome proliferator-activated receptor gammatarget
IcosapentPeroxisome proliferator-activated receptor deltatarget
IcosapentTransient receptor potential cation channel subfamily V member 1target
IcosapentPeroxisome proliferator-activated receptor alphatarget
IcosapentSerum albumincarrier
IcosapentFatty acid-binding protein, braintarget
IcosapentArachidonate 5-lipoxygenasetarget
DoconexentCytochrome P450 2C9enzyme
DoconexentPeroxisome proliferator-activated receptor alphatarget
DoconexentPeroxisome proliferator-activated receptor gammatarget
DoconexentSterol regulatory element-binding protein 1target
DoconexentRetinoic acid receptor RXR-alphatarget
DoconexentRetinoic acid receptor RXR-betatarget
DoconexentRetinoic acid receptor RXR-gammatarget
DoconexentMyc proto-oncogene proteintarget