Imino Acids

Name
Imino Acids
Accession Number
DBCAT000388
Description

Carboxylic acids that contain an imino group (C=NH).

Drugs
DrugDrug Description
ProlineAn amino acid commonly found as a component of total parenteral nutrition.
Technetium Tc-99m disofeninA radiopharmaceutical diagnostic agent used for hepatobiliary scans.
Pidolic acidThere is currently no clinically approved and/or marketed medicine that relies upon pidolic acid as an active ingredient for any formal therapeutic indication. Although pidolic acid may be sold in...
FosinoprilAn ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics.
CaptoprilAn ACE inhibitor used for the management of essential or renovascular hypertension, congestive heart failure, left ventricular dysfunction following myocardial infarction, and nephropathy.
EpicaptoprilNot Available
Pyrrole-2-CarboxylateNot Available
N-AcetylprolineNot Available
5-OxoprolinalNot Available
L-proline betaineNot Available
AB192Investigated for use/treatment in diabetes mellitus type 2.
ZofenoprilatNot Available
HydroxyprolineUsed in France as a combination product for the treatment of small, superficial wounds.
BoceprevirA hepatitis C virus NS3/4A protease inhibitor used in combination with other medications to treat chronic hepatitis C genotype 1 infection. Boceprevir is not indicated as monotherapy.
AzelnidipineFor the treatment of hypertension.
OmbitasvirA direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
ParitaprevirA direct acting antiviral agent used in combination with other antiviral agents for the treatment of Hepatitis C Virus (HCV) infections.
PidotimodA synthetic agent with immunomodulatory properties used in patients with documented cell-mediated immunosuppression to stimulate their immunity during lung and urinary tract infections.
RaxatrigineRaxatrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
DanoprevirDanoprevir has been used in trials studying the treatment of Hepatitis C, Chronic.
FaldaprevirFaldaprevir has been investigated for the treatment of Chronic Hepatitis C.
DanegaptideDanegaptide has been investigated for the treatment of Focus of Study is STEMI.
VaniprevirVaniprevir has been used in trials studying the treatment and diagnostic of Hepatitis C, Chronic Hepatitis C, Hepatitis C, Chronic, Chronic Hepatitis C Infection, and Chronic Genotype 1 Hepatitis C...
VoxilaprevirA nonstructural protein 3 and 4a protease inhibitor used to treat Hepatitis C infections.
Oxothiazolidinecarboxylic acidProcysteine has been used in trials studying the treatment of HIV Infections.
ZofenoprilAn ACE inhibitor indicated in the treatment of hypertension.
OxaceprolNot Annotated
GlecaprevirA Hepatitis C NS3/4A protease inhibitor used to treat Hepatitis C.
FosinoprilatFosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
NarlaprevirNot Annotated
DanicopanDanicopan is under investigation in clinical trial NCT03459443 (A Proof of Concept Study for a 12 Month Treatment in Patients With C3 Glomerulopathy (C3G) or Immune-Complex Membranoproliferative Glomerulonephritis (IC-MPGN)).
EfpeglenatideEfpeglenatide is under investigation in clinical trial NCT03713684 (Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Basal Insulin Alone or in...
FasoracetamFasoracetam is under investigation in clinical trial NCT03609619 (PART B: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and Without Mglur Mutations).
MetadoxineA medication used to increase the clearance of alcohol in patients with chronic alcohol dependancy.
NirmatrelvirAn oral protease inhibitor with emergency use authorization for the treatment of mild-to-moderate COVID-19.
Drugs & Drug Targets
DrugTargetType
ProlinePyrroline-5-carboxylate reductase 1, mitochondrialtarget
ProlineBifunctional glutamate/proline--tRNA ligasetarget
ProlineSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)target
ProlineSodium-dependent proline transportertarget
ProlinePyrroline-5-carboxylate reductase 2target
ProlineProlyl 4-hydroxylase subunit alpha-2target
ProlineProline dehydrogenase 1, mitochondrialtarget
ProlinePeptidyl-prolyl cis-trans isomerase Htarget
ProlineProline synthase co-transcribed bacterial homolog proteintarget
ProlineProlyl 4-hydroxylase subunit alpha-1target
ProlinePeptidyl-prolyl cis-trans isomerase Btarget
ProlinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
ProlinePeptidyl-prolyl cis-trans isomerase Ctarget
ProlinePeptidyl-prolyl cis-trans isomerase Atarget
ProlinePeptidyl-prolyl cis-trans isomerase Gtarget
ProlineProlyl 3-hydroxylase 1target
ProlinePyrroline-5-carboxylate reductasetarget
ProlineProbable proline--tRNA ligase, mitochondrialtarget
ProlineProlyl 3-hydroxylase 2target
ProlineProlyl 3-hydroxylase 3target
ProlinePyrroline-5-carboxylate reductase 3target
ProlineTrans-L-3-hydroxyproline dehydratasetarget
ProlineProline dehydrogenase 1, mitochondrialenzyme
ProlineMonocarboxylate transporter 10transporter
Pidolic acidAlpha-amylase 2Btarget
Pidolic acidVascular endothelial growth factor Atarget
Pidolic acidPancreatic alpha-amylasetarget
Pidolic acidIg lambda-1 chain C regionstarget
Pidolic acidIg lambda chain V-II region MGCtarget
Pidolic acidTrefoil factor 2target
Pidolic acidCytochrome c2target
Pidolic acidDisintegrin and metalloproteinase domain-containing protein 28target
Pidolic acidEndo-1,4-beta-xylanasetarget
Pidolic acidDissimilatory copper-containing nitrite reductasetarget
Pidolic acidKeratin-associated protein 5-2target
Pidolic acidOrexintarget
Pidolic acidC-C motif chemokine 8target
Pidolic acidCytochrome c'target
Pidolic acidPancreatic alpha-amylaseenzyme
FosinoprilAngiotensin-converting enzymetarget
FosinoprilSolute carrier family 15 member 1transporter
FosinoprilSolute carrier family 15 member 2transporter
CaptoprilAngiotensin-converting enzymetarget
CaptoprilSerum albumincarrier
Captopril72 kDa type IV collagenasetarget
CaptoprilMatrix metalloproteinase-9target
CaptoprilP-glycoprotein 1transporter
CaptoprilSolute carrier family 15 member 1transporter
CaptoprilSolute carrier family 22 member 6transporter
CaptoprilLeukotriene A-4 hydrolasetarget
CaptoprilB1 bradykinin receptortarget
EpicaptoprilAngiotensin-converting enzymetarget
EpicaptoprilFEZ-1 proteintarget
EpicaptoprilCarbapenem-hydrolyzing beta-lactamase BlaB-1target
EpicaptoprilMetallo-beta-lactamase L1target
EpicaptoprilBeta-lactamasetarget
EpicaptoprilOrganic hydroperoxide resistance protein, putativetarget
Pyrrole-2-CarboxylateMonomeric sarcosine oxidasetarget
N-Acetylproline(5R)-carbapenem-3-carboxylate synthasetarget
5-OxoprolinalAcidic cytochrome c3target
L-proline betaineGlycine betaine-binding periplasmic proteintarget
AB192Myeloperoxidaseenzyme
ZofenoprilatCytosol aminopeptidasetarget
HydroxyprolineProton-coupled amino acid transporter 1transporter
BoceprevirCytochrome P450 3A4enzyme
BoceprevirCytochrome P450 3A5enzyme
BoceprevirP-glycoprotein 1transporter
BoceprevirNS3/4A proteintarget
AzelnidipineCytochrome P450 3A4enzyme
AzelnidipineVoltage-dependent L-type calcium channel subunit beta-1target
OmbitasvirNonstructural protein 5Atarget
OmbitasvirCytochrome P450 2C8enzyme
OmbitasvirP-glycoprotein 1transporter
OmbitasvirATP-binding cassette sub-family G member 2transporter
OmbitasvirUDP-glucuronosyltransferase 1-1enzyme
ParitaprevirNS3/4A proteintarget
ParitaprevirCytochrome P450 3A4enzyme
ParitaprevirCytochrome P450 3A5enzyme
ParitaprevirATP-binding cassette sub-family G member 2transporter
ParitaprevirP-glycoprotein 1transporter
ParitaprevirSolute carrier organic anion transporter family member 1B1transporter
ParitaprevirSolute carrier organic anion transporter family member 1B3transporter
ParitaprevirUDP-glucuronosyltransferase 1-1enzyme
DanoprevirGenome polyproteintarget
DanoprevirCytochrome P450 3A4enzyme
VoxilaprevirCytochrome P450 3A4enzyme
VoxilaprevirCytochrome P450 1A2enzyme
VoxilaprevirCytochrome P450 2C8enzyme
VoxilaprevirNS3/4A proteintarget
VoxilaprevirP-glycoprotein 1transporter
VoxilaprevirATP-binding cassette sub-family G member 2transporter
VoxilaprevirSolute carrier organic anion transporter family member 1B1transporter
VoxilaprevirSolute carrier organic anion transporter family member 1B3transporter
ZofenoprilAngiotensin-converting enzymetarget
GlecaprevirCytochrome P450 3A Subfamilyenzyme
GlecaprevirUDP-glucuronosyltransferase 1-1enzyme
GlecaprevirP-glycoprotein 1transporter
GlecaprevirATP-binding cassette sub-family G member 2transporter
GlecaprevirSolute carrier organic anion transporter family member 1B1transporter
GlecaprevirSolute carrier organic anion transporter family member 1B3transporter
GlecaprevirNS3 proteasetarget
GlecaprevirCytochrome P450 3A4enzyme
NirmatrelvirReplicase polyprotein 1abtarget
NirmatrelvirCytochrome P450 3A4enzyme
NirmatrelvirP-glycoprotein 1transporter