- Nicotinic Acids
- Accession Number
2-, 3-, or 4-Pyridinecarboxylic acids. Pyridine derivatives substituted with a carboxy group at the 2-, 3-, or 4-position. The 3-carboxy derivative (NIACIN) is active as a vitamin.
Drug Drug Description Niacin A B vitamin used to treat hypertriglyceridemia and pellagra. Nimodipine A calcium channel blocker used to improve neurological outcomes in patients with subarachnoid hemorrhage due to a ruptured intracranial aneurysm. Sorafenib A kinase inhibitor used to treat unresectable liver carcinoma, advanced renal carcinoma, and differentiated thyroid carcinoma. Nicotinamide An ingredient found in a variety of cosmetic products. Arecoline An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the... Niflumic acid A cyclooxygenase-2 inhibitor used to alleviate inflammation, pain, and edema associated with acute and chronic inflammatory conditions, such as rheumatoid arthritis, osteoarthritis, post-operative inflammatory conditions, and physical trauma. Motesanib Investigated for use/treatment in solid tumors. Nicaraven Investigated for use/treatment in cerebrovascular disease (unspecified). N-methylnicotinamide N-methylnicotinamide is an experimental drug with no approved indication. Xanthinol A vasodilatory niacin found in diet supplements. Clonixin An NSAID used to relieve pain associated with arthritis, migraines, and various soft tissue disorders. Nicorandil A vasodilatory drug that functions through potassium channels and intracellular cGMP concentrations commonly used to treat angina. Levamlodipine A calcium channel blocker used to treat hypertension. Morniflumate An NSAID derived from niflumic acid used in the symptomatic treatment of inflammatory conditions of the airways, ENT, and the urogenital and osteoarticular systems. Flunixin Flunixin is a non-steroidal anti-inflammatory drug for use in pigs, cattle and horses. It exerts analgesic and antipyretic effects. This drug is often prepared for use in meglumine salt form.... Peficitinib Peficitinib has been used in trials studying the treatment and basic science of Psoriasis, Pharmacodynamics, Drug Interactions, Colitis, Ulcerative, and RHEUMATOID ARTHRITIS, among others. Merestinib Merestinib has been used in trials studying the treatment of Cancer, Solid Tumor, Advanced cancer, ColoRectal Cancer, and Metastatic Cancer, among others. Ondelopran Ondelopran has been used in trials studying the treatment of Alcohol Dependence. Boscalid Boscalid has been investigated for the treatment of OSDI, Glaucoma, Staining, Schirmers, and Disease Severity, among others. Nifenazone Not Annotated Nicofuranose Not Annotated Niceritrol Not Annotated Nikethamide A nicotinic acid derivative indicated as a respiratory stimulant. Niaprazine Niaprazine is a selective brain catecholamine depletor. Piromidic acid Not Annotated Pipemidic acid A quinolone antibiotic indicated in the treatment of susceptible urinary tract infections. Methyl nicotinate A methyl ester of niacin used to treat muscle and joint pain. Chromium nicotinate A medication used to treat chromium deficiencies and associated symptoms and also in total parenteral nutrition. AZD-4017 AZD-4017 is under investigation in clinical trial NCT01173471 (A Phase IIa Study to Assess the Tolerability, Safety, and Efficacy of AZD4017 for Raised Intra-ocular Pressure). Pimasertib Pimasertib is under investigation in clinical trial NCT01378377 (Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus). Nicotinamide riboside Nicotinamide riboside is under investigation in clinical trial NCT03432871 (Nicotinamide Riboside and Mitochondrial Biogenesis). Trigonellamide Trigonellamide is under investigation in clinical trial NCT01930240 (The Safety of a Hypolipidemic Agent in Healthy Normal Volunteers). GDC-0623 GDC-0623 has been used in trials studying the treatment of Solid Cancers. Asciminib An inhibitor of ABL/BCR-ABL1 tyrosine kinase for the treatment of patients with Philadelphia chromosome-positive CML, including those with the T315I mutation. MK-0668 Not Annotated
- Drugs & Drug Targets