- Anti-Inflammatory Agents
- Accession Number
Substances that reduce or suppress INFLAMMATION.
- ATC Classification
Drug Drug Description Ketorolac An NSAID used to treat moderate to severe pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders, and headaches. Flurbiprofen An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. Bromfenac An NSAID used to treat postoperative pain and inflammation of the eye. Cortisone acetate A steroid hormone used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses and endocrine disorders associated with inadequate production of steroid hormones. Nepafenac An ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery. Bendazac A non-steroidal anti-inflammatory drug (NSAID) available as an eye drop for the treatment of cataracts and as a topical cream for the treatment of dermatitis, eczema, hives, skin ulcers and other inflammatory skin conditions. Pranoprofen A topical anti-inflammatory agent used for the treatment of non-infectious inflammatory conditions such as blepharitis and conjunctivitis. Pranoprofen ophthalmic solution may also be used post-operatively to manage inflammation. Betamethasone A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders. Flunisolide An inhaled corticosteroid used as a prophylactic therapy in the maintenance treatment of asthma. Mesalazine An aminosalicylate drug used to treat mild to moderate active ulcerative colitis and also to maintain remission once achieved. Beclomethasone dipropionate An inhaled corticosteroid used as maintenance treatment in the prophylaxis of asthma attacks. Desoximetasone A glucocorticoid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Fluticasone propionate A glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis. Fluocinolone acetonide A corticosteroid used to treat skin conditions, eczematous otitis externa, diabetic macular edema, and non-infectious uveitis of the posterior segment of the eye. Triamcinolone A glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues. Flumethasone A corticosteroid used to treat contact dermatitis, atopic dermatitis, eczema, psoriasis, diaper rash, and other skin conditions. Hydrocortisone A glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders. Mometasone A corticosteroid with no indications. Prednisolone A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers. Methylprednisolone A corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases. Clobetasol propionate A corticosteroid used to treat corticosteroid-responsive dermatoses and plaque psoriasis. Fluocinonide A high potency corticosteroid commonly used topically for a number of inflammatory skin conditions. Prednicarbate A medium potency topical corticosteroid used to manage pruritus and inflammation associated with responsive skin conditions. Budesonide A corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis. Dexamethasone A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders. Olsalazine An anti-inflammatory agent used in the treatment of inflammatory bowel disease and ulcerative colitis. Desonide A topical corticosteroid used for the symptomatic treatment of inflammatory and pruritic manifestations of corticosteroid responsive dermatoses. Clobetasone A corticosteroid used to treat dry eyes, eczema, and dermatitis. Indomethacin A nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants. Flurandrenolide A corticosteroid used to treat corticosteroid-responsive dermatoses. Adalimumab A monoclonal anti-tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis. Diflorasone A topical corticosteroid used to treat the symptoms of various inflammatory skin conditions that cause erythema, pruritus, and discomfort. Alclometasone A topical corticosteroid used to relieve the symptoms of corticosteroid-responsive dermatoses. Fluorometholone An ophthalmic corticosteroid used for the relief of inflammation located in both the palpebral and bulbar conjunctiva, the cornea, and the anterior segment of the globe of the eye. Nabumetone An NSAID used to treat osteoarthritis and rheumatoid arthritis. Tenoxicam An anti inflammatory analgesic used to treat mild to moderate pain as well as the signs and symptoms of rheumatoid arthritis and osteoarthritis. Celecoxib An NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis. Tolmetin An NSAID used to treat acute flares of various painful conditions and used for the long term management of osteoarthritis, rheumatoid arthritis, and juvenile arthritis. Rofecoxib A COX-2 inhibitor NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, primary dysmenorrhea, and migraine attacks. Piroxicam An NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis. Fenoprofen An anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis. Valdecoxib A COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea. Diclofenac An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis. Sulindac An NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis. Prednisone A corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases. Fludrocortisone A mineralocorticoid used to treat adrenocortical insufficiency and salt-losing adrenogenital syndrome. Nedocromil A pyrano quinoline used to treat allergic conjunctivitis. Etodolac An NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain. Mefenamic acid An NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea. Naproxen An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain. Sulfasalazine An anti-inflammatory drug used to treat Crohn's disease and rheumatoid arthritis. Phenylbutazone An NSAID used to treat backache and ankylosing spondylitis. Meloxicam An NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics. Carprofen For use as a pain reliever in the treatment of joint pain and post-surgical pain. Clocortolone A corticosteroid used to treat inflammatory and pruritic dermatoses of the scalp. Clofazimine A riminophenazine antimycobacterial used to treat leprosy. Diflunisal An NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis. Suprofen An NSAID used to prevent pupil constriction in ocular surgery. Salicylic acid An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. Meclofenamic acid An NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis. Acetylsalicylic acid A salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events. Oxaprozin An NSAID used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis. Ketoprofen An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain. Balsalazide An aminosalicylate used to treat ulcerative colitis. Ibuprofen An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation. Lumiracoxib For the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults. Paramethasone For the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary... Magnesium salicylate An NSAID analgesic used in the symptomatic relief of mild to moderate muscular pain. Salsalate A nonsteroidal anti-inflammatory agent used in the symptomatic relief of rheumatoid arthritis, osteoarthritis and related rheumatic disorders. Choline magnesium trisalicylate Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults. Antipyrine An antipyretic agent used for the symptomatic treatment of acute otitis media, most commonly in combination with benzocaine. Tiaprofenic acid A nonsteroidal anti-inflammatory (NSAID) used to manage inflammation and analgesia associated with rheumatoid arthritis and osteoarthritis. Etoricoxib A selective COX-2 inhibitor used to relieve moderate post-surgical dental pain as a short-term treatment and inflammatory and painful symptoms of various forms of arthritis. Flufenamic acid An analgesic drug used to relieve pain associated with rheumatoid diseases. Oxyphenbutazone A nonsteroidal anti-inflammatory drug (NSAID) no longer commonly used for the symptomatic relief of musculoskeletal pain. Niflumic acid A cyclooxygenase-2 inhibitor used to alleviate inflammation, pain, and edema associated with acute and chronic inflammatory conditions, such as rheumatoid arthritis, osteoarthritis, post-operative inflammatory conditions, and physical trauma. Corticosterone An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437) Nimesulide A cyclooxygenase 2 inhibitor used to treat acute pain and primary dysmenorrhea. Benoxaprofen The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets... Metamizole An antipyretic and analgesic drug used to relieve severe and persistent fever and pain. Zomepirac Zomepirac was indicated for the management of mild to severe pain. CTCE-0214 Investigated for use/treatment in adverse effects (chemotherapy), blood (blood forming organ disorders, unspecified), cancer/tumors (unspecified), neutropenics, and vascular diseases. Lornoxicam An NSAID indicated in the treatment of mild to moderate pain, as well as rheumatoid arthritis and osteoarthritis. Aceclofenac Aceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Zaltoprofen A non-steroidal anti-inflammatory drug approved for use in Japan in 1993. Halcinonide A corticosteroid used for the management and symptomatic relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. Azapropazone Not Available Felbinac Not Available Parecoxib A selective COX-2 inhibitor and NSAID used for the short-term management of perioperative pain. Salicylamide Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. It has similar medicinal uses to aspirin.... Kebuzone Kebuzone (also known as ketophenylbutazone ) is a non-steroidal anti-inflammatory drug. Isoxicam Isoxicam is a non-steroidal anti-inflammatory drug that is not marketed in the United States. Indoprofen A drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide. Ibuproxam Ibuproxam is a non steroidal anti-inflammatory drug (NSAID). Fluocortolone A glucocorticoid used topically for localized skin reactions and also orally for systemic use. Floctafenine An anti-inflammatory analgesic used to manage mild to moderate acute pain. Fenbufen Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is... Etofenamate An NSAID used to treat muscle and joint pain. Epirizole Epirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain. Benzydamine A locally-acting NSAID indicated for the symptomatic relief of pain in acute sore throat and for the symptomatic relief of oropharyngeal mucositis caused by radiation therapy. Difluocortolone A topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis. Loxoprofen An NSAID used to treat pain and inflammation in musculoskeletal conditions. Droxicam Droxicam is an NSAID previously used for the treatment of inflammation and rheumatoid arthritis . Tolfenamic acid In the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults. Clonixin An NSAID used to relieve pain associated with arthritis, migraines, and various soft tissue disorders. Propacetamol Propacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy. Fluprednisolone A synthetic glucocorticoid with anti-inflammatory properties. Tepoxalin Tepoxalin is a nonsteroidal anti-inflammatory drug approved for veterinary use in the United States and many other countries. It is primarily used to reduce inflammation and relief of pain caused... Flunixin Flunixin is a non-steroidal anti-inflammatory drug for use in pigs, cattle and horses. It exerts analgesic and antipyretic effects. This drug is often prepared for use in meglumine salt form.... Clobetasol Clobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids. Deflazacort A corticosteroid used to treat Duchenne muscular dystrophy. Diacerein An slow-onset anthraquinone IL-1 inhibitor used in the treatment of degenerative joint diseases like osteoarthritis. Gadolinium Gadolinium is under investigation in Hypertension, ACUTE KIDNEY INJURY, and Chronic Kidney Disease. Gadolinium has been investigated for the basic science of CAD, Multiple Sclerosis, and Coronary Artery Disease. Nitroaspirin Nitroaspirin has been investigated for the treatment of Intermittent Claudication. Indobufen A reversible platelet aggregation inhibitor used to prevent coronary and peripheral artery occlusion. Lupeol Lupeol has been investigated for the treatment of Acne. Firategrast Firategrast has been used in trials studying the treatment of Multiple Sclerosis. Tinoridine Tinoridine is under investigation in clinical trial NCT01224756 (Efficacy of Tinoridine in Treating Pain and Inflammation in Adults). Cortivazol Cortivazol is under investigation in clinical trial NCT00804895 (Cluster Headache Cortivazol Injection (CHCI)). Enoxolone Enoxolone (glycyrrhetic acid) has been investigated for the basic science of Apparent Mineralocorticoid Excess (AME). Alclofenac Alclofenac is indicated in rheumatology, in particular for the treatment of rheumatoid arthritis, ankylosing spondylitis and, as an analgesic, in painful arthritic pathologies. Fentiazac Not Annotated Suxibuzone Not Annotated Bumadizone Bumadizone has been approved for use in Germany and Austria, it is a drug with anti-inflammatory, antipyretic, and analgesic properties, and was marketed for the treatment of both rheumatoid arthritis... Alminoprofen Alminoprofen is a non-steroidal anti-inflammatory drug (NSAID) whose physiochemical characteristics make it a member of the phenylpropionic acid class of chemical substances. Flunoxaprofen Not Annotated Bufexamac An NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses. Feprazone Not Annotated Difenpiramide Not Annotated Nifenazone Not Annotated Lonazolac Not Annotated Tenidap Not Annotated Propyphenazone Not Annotated Proglumetacin A non-steroidal anti-inflammatory medication used to manage pain associated with various inflammatory conditions including rheumatoid arthritis and osteoarthritis. Guacetisal Not Annotated Ethenzamide Not Annotated Carbaspirin calcium An NSAID indicated in the treatment of short term pain and fever. Mofebutazone Not Annotated Proquazone Not Annotated Benorilate Not Annotated Tacalcitol A vitamin D analog indicated in the treatment of mild to moderate plaque psoriasis. Pirprofen Not Annotated Glycyrrhizic acid Glycyrrhizic acid is widely applied in foods as a natural sweetener. As a therapeutic agent, is has been used in a vast variety of formulations as it is reported to... Acemetacin A NSAID indicated in the treatment of pain and inflammation. Imidazole salicylate Not Annotated Fluticasone A corticosteroid indicated in the treatment of corticosteroid responsive dermatoses, asthma, and COPD. Methyl nicotinate A methyl ester of niacin used to treat muscle and joint pain. Medrysone A topical glucocorticoid applied ophthalmically for the treatment of various ocular inflammatory or allergic conditions. Rimexolone A glucocorticoid used to treat inflammation of the eye. Yttrium Y-90 Yttrium 90 has been investigated for the treatment of Colon Cancer and Colorectal Cancer. Gold Au-198 Not Annotated Formocortal Not Annotated Rhenium Re-186 sulfide Not Annotated Amcinonide A topical corticosteroid used in the treatment of inflammation and pruritus due to a variety of dermatoses. Ulobetasol A lipocortin corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Robenacoxib Robenacoxib is a non-steroidal anti-inflammatory drug used in veterinary medicine for the relief of pain and inflammation in cats and dogs. Icosapent A polyunsaturated fatty acid, usually found in fish oils, that is used in many supplements. Antrafenine Antrafenine is used as an anti-inflammatory and analgesic agent for the relief of mild to moderate pain. Cimicoxib Investigated for use/treatment in depression. Dexibuprofen A pharmacologically active enantiomer of racemic ibuprofen (NSAID) used to treat pain and inflammation. Trolamine salicylate A medication used to relieve minor aches and pains of the muscles and joints. Aminophenazone An analgesic drug used to treat acute migraine attacks in combination with ergotamine and caffeine. Chloroquine An antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis. Zileuton A leukotriene synthesis inhibitor used in the prophylaxis and treatment of chronic asthma. Lifitegrast A medication used to treat dry eye disease. Etanercept A protein therapy based on the binding fragment of the tumour necrosis factor alpha receptor used to treat severe rheumatoid arthritis and moderate to severe plaque psoriasis. Masoprocol Used for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated). Pimecrolimus A topical calcineurin inhibitor used in the treatment of mild-moderate atopic dermatitis who are not candidates for other types of therapy due to previous lack of response or other reasons. Olopatadine A histamine H1 antagonist used to treat allergic conjunctivitis and rhinitis. Pirfenidone An agent used for the treatment of idiopathic pulmonary fibrosis (IPF). Apremilast A non-steroidal medication used for the treatment of inflammatory conditions such as psoriasis and psoriatic arthritis. Icatibant A bradykinin B2 receptor antagonist used to treat acute episodes of swelling and inflammation associated with hereditary angioedema (HAE). Teriflunomide A pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis. Curcumin No approved therapeutic indications. Parthenolide Parthenolide has been used in trials studying the diagnostic of Allergic Contact Dermatitis. SC-236 SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , . NS-398 NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases. Firocoxib Used for the treatment of pain inflammation and fever in horses and dogs. Adapalene A third-generation topical retinoid with anti-comedogenic, comedolytic, and anti-inflammatory properties used to treat acne vulgaris in adolescents and adults. Dimethyl sulfone Not Annotated Morniflumate An NSAID derived from niflumic acid used in the symptomatic treatment of inflammatory conditions of the airways, ENT, and the urogenital and osteoarticular systems. Talniflumate Talnifumate is a phthalidyl ester of nifumic acid, which has potent analgesic and anti-inflammatory effects and is widely used to treat inflammatory disorders, such as rheumatoid arthritis and osteoarthritis ,... Dexketoprofen An NSAID that is the R(-)-enantiomer of racemic ketoprofen with analgesic and anti-inflammatory properties used for the treatment of mild to moderate pain. Mometasone furoate A corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus. Hydrocortisone acetate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses and ulcerative colitis. Hydrocortisone probutate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Hydrocortisone succinate A corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders. Hydrocortisone valerate A corticosteroid used to treat inflammatory and pruritic corticosteroid-responsive dermatoses. Loteprednol A corticosteroid indicated in the treatment of pain and inflammation after cataract surgery. Methylprednisolone aceponate A corticosteroid indicated in the treatment of corticosteroid-responsive dermatoses. Methylprednisolone hemisuccinate A water soluble corticosteroid used to treat severe allergic reactions, dermatologic diseases, endocrine disorders, gastrointestinal diseases, hematological disorders, neoplastic diseases, nervous system conditions, ophthalmic diseases, renal diseases, respiratory diseases, and rheumatic disorders. Prednisone acetate Not Annotated Dexamethasone acetate Commonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is... Prednisolone phosphate A corticosteroid used to treat inflammation, immune reactions, as well as endocrine or neoplastic conditions. Taxifolin Not Available Betulinic Acid Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome. Ebselen Ebselen has been investigated for the treatment and basic science of Meniere's Disease, Type 2 Diabetes Mellitus, and Type 1 Diabetes Mellitus. Cortisone A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to... Flurbiprofen axetil Flurbiprofen axetil is under investigation in clinical trial NCT02043366 (Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients). Crisaborole A non-steroidal topical medication used for the treatment of mild-moderate atopic dermatitis. Polmacoxib Polmacoxib has been used in trials studying the treatment of Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Localized Primary Osteoarthritis of Hip, and Localized Primary Osteoarthritis of Knee. Licofelone For the management of osteoarthritis. Ecallantide A kallikrein inhibitor used to prevent and treat acute attacks caused by Hereditary Angioedema (HAE). Rilonacept An IL-1 inhibitor used to treat cryopyrin-associated periodic syndrome, a rare hereditary inflammatory disorder. Lycopene An ingredient found in a variety of supplements and vitamins. Tafamidis A medication used to treat transthyretin-mediated amyloidosis. Bergapten Bergapten is under investigation in clinical trial NCT00533195 (Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis). Lexaptepid pegol Lexaptepid pegol has been used in trials studying the treatment of Anemia, Inflammation, Chronic Diseases, End Stage Renal Disease, and Anemia of Chronic Disease. Lorecivivint Lorecivivint is under investigation in clinical trial NCT03246399 (A Study of the Safety, Tolerability, and Pharmacokinetics of SM04690 Injectable Suspension Following Single Intradiscal Injection in Subjects With Degenerative Disc Disease). Vamorolone Vamorolone is under investigation in clinical trial NCT03439670 (A Study to Assess the Efficacy and Safety of Vamorolone in Boys With Duchenne Muscular Dystrophy (DMD)). Umirolimus Not Annotated Prednisolone acetate A glucocorticoid used to treat a wide variety of endocrine, inflammatory, and immune conditions as well as for palliation of neoplastic conditions. MIV-711 Not Annotated Bisindolylmaleimide I Not Available Piroxicam cinnamate An anti-inflammatory drug indicated to treat pain and inflammation. Fepradinol Not Annotated Dapansutrile Dapansutrile is under investigation in clinical trial NCT01768975 (Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee). Peoniflorin Peoniflorin is under investigation in clinical trial NCT02878863 (Paeoniflorin Combination of Hepatoprotective Drugs Versus Hepatoprotective Drugs Only for Auto-immune Hepatitis). Famprofazone Famprofazone is a nonsteroidal anti-inflammatory agent found in combination products such as ‘Gewodin’ which is marketed in Taiwan. It is important to note that the drug is metabolized to methamphetamine... Dimethyl fumarate A medication used to treat patients with the relapsing-remitting form of multiple sclerosis. Menthyl salicylate For the temporary relief of pain associated with rheumatism, arthritis, neuralgia, sprains and strains of joints and muscles, lumbago and fibrositis . Glycol salicylate A salicylate used to treat mild to moderate muscle pain. CP-96345 Not Annotated Flunisolide acetate Not Annotated CXA-10 CXA-10 is under investigation in clinical trial NCT03422510 (FIRSTx - A Study of Oral CXA-10 in Primary Focal Segmental Glomerulosclerosis (FSGS)). Galiximab Investigated for use/treatment in lymphoma (non-hodgkin's), psoriasis and psoriatic disorders, bone metastases, multiple myeloma, prostate cancer, and rheumatoid arthritis. Andrographolide Investigated for use/treatment in ulcerative colitis. Golimumab A TNFα inhibitor used in the symptomatic treatment of various active inflammatory disorders, such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. Dexamethasone isonicotinate Dexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, topically, and parenterally. Its unintended mineralocorticoid action may cause salt and water retention. Bindarit Bindarit has been used in trials studying the prevention and treatment of Coronary Restenosis and Diabetic Nephropathy. Halometasone A corticosteroid indicated in the treatment of corticosteroid responsive dermatoses. Remestemcel-L Indicated for in the management of acute Graft versus Host Disease (aGvHD) in pediatric patients. Acute GvHD should be refractory to treatment with systemic corticosteroid therapy and/or other immunosuppressive agents.... Clocortolone acetate Not Annotated Lenzilumab Lenzilumab is under investigation in clinical trial NCT02546284 (Study of Lenzilumab in Previously Treated Patients With Chronic Myelomonocytic Leukemia (CMML)). Gimsilumab Gimsilumab is under investigation in clinical trial NCT01357759 (Safety and Tolerability of MORAb-022 in Healthy and Rheumatoid Arthritis Subjects). Algestone acetophenide A progestin indicated in combination with an estrogen as an injectable contraceptive. Fluocortolone pivalate A corticosteroid used to treat corticosteroid-responsive dermatoses and hemorrhoids. Fluocortolone caproate A corticosteroid indicated in the treatment of hemorrhoids, anal fissures, and corticosteroid-responsive dermatoses. Nangibotide Nangibotide is under investigation in clinical trial NCT04055909 (Efficacy, Safety and Tolerability of Nangibotide in Patients With Septic Shock). Astegolimab Astegolimab is under investigation in clinical trial NCT04386616 (A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia). Avdoralimab Avdoralimab is under investigation in clinical trial NCT04333914 (Prospective Study in Patients With Advanced or Metastatic Cancer and Sars-cov-2 Infection). Mirikizumab Mirikizumab is under investigation in clinical trial NCT03053622 (A Study of Mirikizumab (LY3074828) Injection in Healthy Participants). Veliflapon Veliflapon is under investigation in clinical trial NCT00353067 (Veliflapon (Dg-031)to Prevent Heart Attacks or Stroke in Patients With a History of Heart Attack or Unstable Angina). Infliximab A monoclonal anti tumor necrosis factor alpha antibody used in the treatment of a wide variety of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis. Cromoglicic acid A medication used to treat asthma, allergic reactions of the eyes and nose, as well as other mast cell reactions. Castanospermine Not Available Tarenflurbil Investigated for use/treatment in alzheimer's disease and prostate cancer. Exisulind Investigated for use/treatment in adenomatous polyposis coli, lung cancer, prostate cancer, colon polyps, Barrett's esophagus disease, and pediatric indications. Seratrodast Seratrodast (INN) is a thromboxane receptor antagonist used primarily in the treatment of asthma. Tranilast For the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis. Ferulic acid Not Available Certolizumab pegol A tumor necrosis factor (TNF) blocker used to treat a variety of autoimmune and autoinflammatory conditions like Crohn's disease, rheumatoid arthritis, active psoriatic arthritis, ankylosing spondylitis, axial spondyloarthritis, and plaque psoriasis. Evening primrose oil Evening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical... Anisodamine Anisodamine has been investigated for the treatment of Intestinal Diseases. Semapimod Semapimod has been used in trials studying the treatment of Crohn Disease. Bucillamine Bucillamine has been used in trials studying the treatment and prevention of Gout and Rheumatoid Arthritis. Lisofylline Lisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus. Nafamostat Used as an anticoagulant in patients with disseminative blood vessel coagulation, hemorrhagic lesions, and hemorrhagic tendencies. It prevents blood clot formation during extracorporeal circulation in patients undergoing continuous renal replacement... Mizoribine Mizoribine has been investigated for the treatment of Rheumatoid Arthritis. Apocynin Acetovanillone has been used in trials studying the treatment of Bronchial Asthma and Chronic Obstructive Pulmonary Disease. Higenamine Higenamine is under investigation in clinical trial NCT01451229 (Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects). Serrapeptase A protease indicated in the treatment of post-surgical inflammation. Tribenoside An anti-inflammatory agent that reduces vascular permeability and causes vasoconstriction to treat internal and external hemorrhoids. Bevonium Not Annotated Palmidrol A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection. Palmidrol is available for human use as a supplement (400 mg capsules) and as food... Ursolic acid Not Annotated
- Drugs & Drug Targets