Food Additives

Name
Food Additives
Accession Number
DBCAT000377
Description

Substances which are of little or no nutritive value, but are used in the processing or storage of foods or animal feed, especially in the developed countries; includes ANTIOXIDANTS; FOOD PRESERVATIVES; FOOD COLORING AGENTS; FLAVORING AGENTS; ANTI-INFECTIVE AGENTS (both plain and LOCAL); VEHICLES; EXCIPIENTS and other similarly used substances. Many of the same substances are PHARMACEUTIC AIDS when added to pharmaceuticals rather than to foods.

Drugs
DrugDrug Description
AspartameUsed as a diet supplement and sugar substitute.
MannitolA sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, and to measure glomerular filtration rate.
Edetic acidA chelating agent used to treat mercury and lead toxicity and some blood transfusion dependent anemias.
SorbitolA product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener.
SucroseA nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as...
MaltoseA dextrodisaccharide from malt and starch. It is used as a sweetening agent and fermentable intermediate in brewing. (Grant & Hackh's Chemical Dictionary, 5th ed)
Benzoic acidAn antimicrobial food additive.
FructoseNot Available
LactoseAn additive and filler found in various products to maintain structure and consistency.
Nitrous acidAn iron binder used to reverse life-threatening acute cyanide poisoning.
Invert sugarInvert sugar presents a large variety of uses. It can be used therapeutically for parenteral hyperalimentation or to be used as an excipient with a known effect. Invert sugar is...
Calcium citrateAn ingredient found in a variety of supplements and vitamins.
XylitolAn ingredient added to dental products to remove bacteria.
Xanthan gumXanthan gum is a polysaccharide gum derived from* Xanthomonas campestris* by a pure-culture fermentation process and purified by recovery with isopropyl alcohol. The major constituents include D-glucose, D-mannose, and D-glucuronic...
SaccharinSaccharin has been investigated for the treatment of Hypertension and Hyperglycemia.
LactitolAn orally administered osmotic laxative used to treat chronic idiopathic constipation.
CinnamaldehydeCinnamaldehyde is approved by the FDA for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in...
D-glucoseA most commonly occurring isomer of glucose used as a carbohydrate supplementation in case of nutrient deprivation and metabolic disorders, such as hypoglycemia.
BetadexNot Available
PolydextrosePolydextrose is under investigation in clinical trial NCT02258750 (Assessing a Polydextrose Containing Soup on Food Intake, Appetite and Biomarkers of Satiation and Satiety).
SucraloseSucralose is an artificial sweetener used as a sugar substitute.
EucalyptolA common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion.
Sodium citrateAn ingredient used for the anticoagulation of whole blood as part of automated apheresis procedures.
PectinPectin is used in food as a gelling agent and stabilizer. As a medical drug, it has obtained a great interest in its potential use as a source of dietary...
SteviolbiosideSteviolbioside has been used in trials studying the treatment of HIV-1 Infection.
Drugs & Drug Targets
DrugTargetType
AspartameTaste receptor type 1 member 2target
AspartameTransient receptor potential cation channel subfamily V member 1target
AspartameSolute carrier family 22 member 6transporter
AspartameSolute carrier family 22 member 8transporter
AspartameSolute carrier family 22 member 11transporter
AspartameTaste receptor type 1 member 3target
MannitolMannitol dehydrogenaseenzyme
Edetic acidLeadtarget
Edetic acidIrontarget
Edetic acidManganese cationtarget
Edetic acidAdenosine deaminaseenzyme
Edetic acidSerum paraoxonase/lactonase 3enzyme
Edetic acidCytochrome P450 19A1enzyme
SucroseBeta-lactamasetarget
SucroseLysozyme Ctarget
SucroseActin, alpha skeletal muscletarget
SucroseBeta-glucosidasetarget
SucroseAmylosucrasetarget
SucroseBeta-lactamasetarget
SucroseBeta-lactamase CTX-Mtarget
SucroseHeme oxygenasetarget
SucroseCopper transport protein ATOX1target
SucrosetRNA-splicing ligase RtcB homologtarget
SucroseOrange carotenoid-binding proteintarget
SucroseSucrose porintarget
SucroseLevansucrasetarget
SucroseTaste receptor type 1 member 2target
MaltoseCyclomaltodextrin glucanotransferasetarget
MaltoseAlpha-amylase 2Btarget
MaltoseBeta-amylasetarget
MaltoseMaltogenic alpha-amylasetarget
MaltoseMaltodextrin phosphorylasetarget
MaltoseMaltose-binding periplasmic proteintarget
MaltoseAlpha-glucosidasetarget
MaltoseMaltose binding proteintarget
MaltoseMalto-oligosyltrehalose trehalohydrolasetarget
Benzoic acidCocaine esterasetarget
Benzoic acidD-amino-acid oxidasetarget
Benzoic acidChlorocatechol 1,2-dioxygenasetarget
Benzoic acid2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasetarget
Benzoic acidNon-heme chloroperoxidasetarget
Benzoic acidOxygen-insensitive NAD(P)H nitroreductasetarget
Benzoic acidHydroxyquinol 1,2-dioxygenasetarget
Benzoic acidReplication proteintarget
Benzoic acidSolute carrier organic anion transporter family member 2B1transporter
Benzoic acidSolute carrier family 22 member 8transporter
Benzoic acidMonocarboxylate transporter 1transporter
Benzoic acidSolute carrier family 15 member 1target
FructoseMaltoporintarget
LactoseBeta-galactosidasetarget
LactoseGlycosyltransferase 6 domain-containing protein 1target
LactoseGlycolipid transfer proteintarget
LactoseHydrolasetarget
LactoseEndo-1,4-beta-xylanase Atarget
LactoseGalectin-3target
LactoseSialidasetarget
LactoseBeta-galactosidasetarget
Nitrous acidHemoglobin subunit alphatarget
Nitrous acidHemoglobin subunit betatarget
Nitrous acidMyoglobintarget
Invert sugarSolute carrier family 2, facilitated glucose transporter member 2transporter
Invert sugarSolute carrier family 2, facilitated glucose transporter member 5transporter
Invert sugarGlucokinaseenzyme
Invert sugar6-phosphofructokinaseenzyme
Calcium citrateTransient receptor potential cation channel subfamily V member 6transporter
Calcium citrateCalbindincarrier
Calcium citrateProtein S100-Gcarrier
Calcium citrateSodium/calcium exchanger 1transporter
Calcium citrateTransient receptor potential cation channel subfamily V member 5transporter
Calcium citrateExtracellular calcium-sensing receptortarget
Calcium citrateCalreticulintarget
Calcium citrateCalcium and integrin-binding protein 1target
Calcium citrateProgrammed cell death protein 6target
Calcium citrateSorcintarget
Calcium citrateCalcineurin B homologous protein 1target
Calcium citrateSPARCtarget
Calcium citrateCalnexintarget
Calcium citrateFibrillin-2target
Calcium citrateProtein S100-Btarget
Calcium citrateCalsequestrin-2target
Calcium citrateRegucalcintarget
Calcium citratePeflintarget
Calcium citrateProtein S100-A6target
Calcium citrateTranslationally-controlled tumor proteintarget
Calcium citrateCalcium and integrin-binding family member 2target
Calcium citrateProtein S100-A13target
Calcium citrateCalsequestrin-1target
Calcium citrateNucleobindin-1target
Calcium citrateNucleobindin-2target
Calcium citrateCalmodulintarget
Calcium citrateFibrillin-3target
Calcium citrateGrancalcintarget
Calcium citrateCalcium-dependent secretion activator 1target
Calcium citrateSerum albumincarrier
Calcium citrateCalmodulin-2target
Calcium citrateCalmodulin-3target
Calcium citrateProtein S100-A16target
Calcium citrateCalretinintarget
Calcium citrateCalcyphosintarget
Calcium citrateCalcium-dependent secretion activator 2target
Calcium citrateCalreticulin-3target
Calcium citrateRyanodine receptor 1transporter
Calcium citrateRyanodine receptor 2transporter
Calcium citratePolycystic kidney disease 2-like 1 proteintransporter
Calcium citrateNeurexin-1target
Calcium citrateNeuronal calcium sensor 1target
Calcium citrateRyanodine receptor 3transporter
Calcium citratePolycystic kidney disease protein 1-like 3transporter
Calcium citrateCation channel sperm-associated protein 1transporter
Calcium citrateVoltage-dependent L-type calcium channeltransporter
Calcium citrateVoltage-dependent P/Q-type calcium channeltransporter
Calcium citrateVoltage-dependent T-type calcium channeltransporter
Calcium citrateVoltage-dependent R-type calcium channeltransporter
XylitolXylose isomerasetarget
XylitolXylose isomerasetarget
XylitolXylose isomerasetarget
XylitolXylose isomerasetarget
XylitolHyaluronate lyasetarget
SaccharinCarbonic anhydrase 3target
D-glucoseHexokinase-1enzyme
D-glucoseGlucokinaseenzyme
D-glucoseSolute carrier family 2, facilitated glucose transporter member 1transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 2transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 3transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 4transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 5transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 6transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 7transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 8transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 9transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 10transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 11transporter
D-glucoseSolute carrier family 2, facilitated glucose transporter member 12transporter
D-glucoseSodium/glucose cotransporter 1transporter
D-glucoseSodium/glucose cotransporter 2transporter
D-glucoseSerum albumincarrier
BetadexNeopullulanase 2target
BetadexMaltose-binding periplasmic proteintarget
BetadexMaltogenic amylasetarget
Sodium citrateMitochondrial 2-oxodicarboxylate carriertransporter
Sodium citrateSolute carrier family 13 member 2transporter
Sodium citrateSolute carrier family 13 member 5transporter
Sodium citrateTricarboxylate transport protein, mitochondrialtransporter