Acute Myeloid Leukemia (DBCOND0029883)

Identifiers

Synonyms
Acute Myeloblastic Leukaemia / Acute Myelogenic Leukemia / Acute Myeloid Leukaemia / Acute Myelocytic Leukemia / Leukemia, Nonlymphoblastic, Acute / Acute Myeloblastic Leukemia / Acute Myelogenous Leukemia / Acute Granulocytic Leukemia / Acute Myeloid Leukemia (AML) / Acute Myeloid Leucemia / Acute Myeloid Leukaemias (AML) / Acute Myeloid Leukemias / Acute Myelogenous Leukemia (AML) / AML / Acute Myeloid Leukaemia (AML) / Acute myeloid leukemia / Acute Leukemia, Myeloid / Myeloid leukemia, acute / Acute myelogenous leukaemia / Leukaemias acute myeloid / Acute myeloblastic leukemia, not having achieved remission / Acute myeloid leukemia (morphologic abnormality) / Acute myeloid leukemia (disorder) / Leukemia, Myeloid, Acute / Acute myelocytic leukaemia / Leukaemia myeloblastic acute / Non-lymphoblastic leukaemia acute / Non-lymphoblastic leukemia acute / Acute myeloid leukemia NOS / Myeloid leukaemia, acute / Leukemia myeloblastic acute / Acute granulocytic leukaemia / Acute myeloid leukaemia NOS / Acute myeloid leukemia without maturation, FAB M1 (disorder) / Myeloid Leukemia, Acute, M1 / Acute myeloid leukemia without maturation (morphologic abnormality) / Refractory anemia with excess blasts in transformation / Refractory anaemia with excess blasts in transformation / Acute myeloid leukemia with minimal differentiation (morphologic abnormality) / Acute myeloid leukaemia with minimal differentiation / Acute myeloid leukemia with minimal differentiation / Acute myeloid leukemia with maturation, FAB M2 (disorder) / Leukemia, Myeloid, Acute, M2 / Acute myeloid leukemia with maturation (morphologic abnormality)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Azacitidine
A pyrimidine nucleoside analogue used to treat certain subtypes of myelodysplastic syndrome.
Cyclophosphamide
A nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma.
Cytarabine
A pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia.
Doxorubicin
A medication used to treat various cancers, including AIDS-associated Kaposi's Sarcoma and metastatic cancers.
Etoposide
A podophyllotoxin derivative used to treat testicular and small cell lung tumors.
Filgrastim
A form of recombinant human granulocyte colony stimulating factor used to induce the production of granulocytes and lower infection risk after myelosuppressive therapy.
Gemtuzumab ozogamicin
A monoclonal anti-CD33 antibody used to treat CD33-positive acute myeloid leukemia.
Glasdegib
A sonic hedgehog receptor inhibitor used to treat newly diagnosed acute myeloid leukemia in patients over 75 years who cannot receive intense chemotherapy.
Idarubicin
An anthracycline antineoplastic agent used to treat acute myeloid leukemia (AML) in adults.
Ivosidenib
An isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia and cholangiocarcinoma in adults with a susceptible IDH1 mutation.
Midostaurin
An antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
Mitoxantrone
A chemotherapeutic agent used for the treatment of secondary progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis.
Sargramostim
A modified form of recombinant human granulocyte-macrophage colony stimulating factor used to increase immune cell production after myelosuppressive therapy or bone marrow transplant.
Topotecan
An antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer.
Venetoclax
A BCL-2 inhibitor used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, or acute myeloid leukemia.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06598384
VA as Maintenance Therapy Post Allo-HSCT in MDS and AMLtreatment2not_yet_recruiting
NCT06618001
A Study of JNJ-89853413 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic NeoplasmsNo drug interventionstreatment1not_yet_recruiting
NCT06621199
Mitoxantrone Hydrochloride Liposome in Combination With Cytarabine and Venetoclax Regimen in Newly Diagnosed Elderly AMLtreatment2recruiting
NCT01371981
Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment3active_not_recruiting
NCT02926586
Fludarabine and Cytarabine Versus High-dose Cytarabine for CBF-AMLtreatment4completed
NCT03068819
Cytokine Induced Memory-like NK Cell Adoptive Therapy for Relapsed AML After Allogeneic Hematopoietic Cell TransplantNo drug interventionstreatment1 / 2recruiting
NCT03232268
HLA-mismatched Microtransplantation Without Immunosuppressive Treatment in Patients With Myeloid HemopathiesNo drug interventionstreatment1active_not_recruiting
NCT03441048
Lintuzumab-Ac225 in Combination With Cladribine + Cytarabine + Filgastrim + Mitoxantrone (CLAG-M) for Relapsed/Refractory Acute Myeloid Leukemiatreatment1completed
NCT03839771
A Study of Ivosidenib or Enasidenib in Combination With Induction Therapy and Consolidation Therapy, Followed by Maintenance Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myedysplastic Syndrome EB2, With an IDH1 or IDH2 Mutation, Respectively, Eligible for Intensive Chemotherapytreatment3active_not_recruiting
NCT04093570
A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)treatment2enrolling_by_invitation
NCT04256317
A Study of ASTX030 (Cedazuridine in Combination With Azacitidine) in MDS, CMML, or AMLtreatment2 / 3recruiting
NCT04314401
National Cancer Institute "Cancer Moonshot Biobank"No drug interventionsNot AvailableNot Availablerecruiting
NCT04982354
Induction Therapy for Patients With FLT3 Mutated Acute Myeloid Leukemiatreatment1 / 2withdrawn
NCT05275439
Phase 1 Study of Shattuck Labs (SL)-172154 in Subjects with MDS or AMLtreatment1active_not_recruiting
NCT05413018
An Efficacy and Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy in Chinese Participants With Acute Myeloid Leukemia in Complete Remissiontreatment2active_not_recruiting
NCT05554393
Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)treatment2recruiting
NCT05554406
Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)treatment2recruiting
NCT05564390
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)screening2recruiting
NCT05955261
A Study of Venetoclax in Combination With Conventional Chemotherapy in Pediatric Patients With Acute Myeloid Leukemiatreatment2recruiting
NCT06058741
A Study to Asses Effectiveness and Treatment Management of Oral Venetoclax Tablets + Subcutaneously Injected Azacitidine in Adult Participants Ineligible for Intensive Chemotherapy With de Novo Acute Myeloid Leukemia (AML) in ItalyNo drug interventionsNot AvailableNot Availablerecruiting
NCT06191263
Safety and Efficacy of RVU120 Combined with Venetoclax for Treatment of Relapsed/Refractory AMLtreatment2recruiting
NCT06284486
A Multi-Site Break Through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Menin in AML MRD Using the Combination of Venetoclax and Revumenibtreatment2recruiting
NCT06317649
Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)treatment2recruiting
NCT06370000
Oral Azacitidine in Transplant-Eligible Patients With Acute Myeloid Leukemia (AML) Suffering From Health-Inequalitytreatment4not_yet_recruiting
NCT06492707
DR-18 for the Treatment of Relapsed or Persistent Acute Myeloid Leukemia or Myelodysplastic Syndrome After Hematopoietic Cell Transplantation, the DR. DREAM TrialNo drug interventionstreatment1recruiting
NCT06626633
2321GCCC: CRD3874-SI in Patients with Relapsed/refractory AMLNo drug interventionstreatment1recruiting
NCT06626893
Integrative "Omics" Approaches for Leukemia Target Identification and Matched Therapeutic InterventionNo drug interventionsbasic_scienceNot Availablerecruiting
NCT04522895
IDH2-Post-Allo-Trial for Patients with IDH2-mut Myeloid Neoplasms After Allo-SCTtreatment2completed
NCT04570709
RN-Led Palliative and Supportive Care InterventionNo drug interventionssupportive_careNot Availablecompleted
NCT04609826
A Study of JNJ-74856665 in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)No drug interventionstreatment1active_not_recruiting
NCT04726241
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group StudyNo drug interventionsscreening1 / 2recruiting
NCT04730258
A Study of CFI-400945 With or Without Azacitidine in Patients With AML, MDS or CMMLtreatment1 / 2recruiting
NCT04746235
Venetoclax and ASTX727 for the Treatment of Relapsed, Refractory, or Newly Diagnosed Acute Myeloid Leukemiatreatment2recruiting
NCT04774393
Decitabine/Cedazuridine and Venetoclax in Combination With Ivosidenib or Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemiatreatment1 / 2recruiting
NCT04811560
A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemiatreatment1 / 2recruiting
NCT04827069
A Clinical Trial to Evaluate Clifutinib in Patients with Relapsed or Refractory Acute Myeloid Leukemia(AML)No drug interventionstreatment1completed
NCT04953897
Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Renal Impairmenttreatment1recruiting
NCT04953910
Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairmenttreatment1recruiting
NCT04988555
A Study of DSP-5336 in Relapsed/refractory AML/ ALL with or Without MLL Rearrangement or NPM1 Mutationtreatment1 / 2recruiting
NCT05010122
ASTX727, Venetoclax, and Gilteritinib for the Treatment of Newly Diagnosed, Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrometreatment1 / 2recruiting
NCT05015426
Gamma Delta T-cell Infusion for AML at High Risk of Relapse After Allo HCTNo drug interventionstreatment1active_not_recruiting
NCT05168202
A Study to Assess the Effect of CC-95251 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndromestreatment1completed
NCT05197426
A Study to Compare the Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Best Supportive Care as Maintenance Therapy in Japanese Participants With Acute Myeloid Leukemia (AML) in Complete Remissiontreatment2active_not_recruiting
NCT05305859
Venetoclax Combining Chidamide and Azacitidine (VCA) in the Treatment of R/R AMLtreatment2recruiting
NCT05322850
Phase I/II Trial: Engineered Donor Graft (Orca Q) for Pediatric Hematopoietic Cell Transplant (HCT)No drug interventionstreatment1 / 2suspended
NCT05360160
A Phase I-II Study Investigating the All Oral Combination of the Menin Inhibitor SNDX-5613 With Decitabine/Cedazuridine (ASTX727) and Venetoclax in Acute Myeloid Leukemia (SAVE)treatment1 / 2recruiting
NCT05362773
A Study of MGD024 in Patients With Relapsed or Refractory Hematologic MalignanciesNo drug interventionstreatment1recruiting
NCT05424380
A Phase 1, Open Label Study of Intravenous GSK3745417 to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Determine RP2D & Schedule in Participants With Relapsed or Refractory Myeloid Malignancies Including AML and HR MDSNo drug interventionstreatment1terminated
NCT05444348
Compassionate Communication and Advance Care Planning to Improve End of Life Care in Treatment of Hematological Disease (ACT)No drug interventionssupportive_careNot Availablerecruiting
NCT05453903
A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapiestreatment1recruiting
NCT05457556
Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrometreatment3recruiting
NCT05470140
A Phase 1 Study of WU-NK-101 in Patients With Relapsed or Refractory (R/R) Acute Myeloid Leukemia (AML)treatment1active_not_recruiting
NCT05583552
Study to Evaluate Imetelstat in Patients With High-Risk MDS or AML Failing HMA-based Therapytreatment2recruiting
NCT05659992
Clinical Study of Venetoclax Combined with CACAG Regimen in the Treatment of Newly Diagnosed Acute Myeloid Leukemiatreatment2completed
NCT05766514
Trial of Cladribine and Low-Dose Cytarabine (LoDAC) Alternating With Decitabine vs. Hypomethylating Agents (HMA) Plus Venetoclax as Frontline Therapy for AML or High-Grade MDS in Patients Unfit for Intensive Inductiontreatment2not_yet_recruiting
NCT05772273
PD-1 Inhibitor, Azacitidine and Low-dose DLI in AML Relapse After Allo-HSCTtreatmentNot Availablerecruiting
NCT05800210
Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant DiseasesNo drug interventionstreatment2recruiting
NCT05817058
First-in-Human Dose Escalation Study of AFM28 in Patients With Relapsed/Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1recruiting
NCT05823480
Magrolimab in Combination with Azacitidine After Allogeneic HCTin Treating Patients with High-Risk AML or MDStreatment1withdrawn
NCT05961839
Study of SGR-2921 in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic SyndromeNo drug interventionstreatment1recruiting
NCT06059391
CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplanttreatment2recruiting
NCT06068868
Study to Evaluate Adverse Events and Movement of Intravenously (IV) Infused ABBV-787 in Adult Participants With Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)No drug interventionstreatment1recruiting
NCT06158100
Venetoclax in Combination With Azacitidine (VEN/AZA) Followed by Donor Lymphocyte Infusion (DLI) for Patients With Very High-Risk Acute Myeloid Leukemia (AML) Undergoing Allogeneic Hematopoietic Cell Transplant (HCT)treatment1not_yet_recruiting
NCT06191978
A Phase Ia/Ib Open-label, Multiple Dose, Study to Determine the Recommended Dose, Evaluate PKs, PDs, Safety, and Activity of Venetoclax in Combination With Oral Decitabine/Cedazuridine (ASTX727) in Pediatric Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML)treatment1recruiting
NCT06382168
DFP-10917 in Combination With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemiatreatment1 / 2recruiting
NCT06386302
Chidamide, Venetoclax, and Azacitidine for Newly Diagnosed Acute Myeloid LeukemiatreatmentNot Availablerecruiting
NCT06439199
Biological, Prospective Study Evaluating the Dosage of Plasma Cytokines Including the FLT3 Ligand and IL6 of Patients Treated With Non-intensive ChemotherapyNo drug interventionsNot AvailableNot Availablerecruiting
NCT06440135
Ziftomenib Maintenance Post Allo-HCTtreatment1recruiting
NCT06508489
A Study to Investigate Natural Killer Cell Engager (SAR443579) With Different Agents in Participants With Hematological Malignanciestreatment1 / 2recruiting
NCT06613035
Twice-per-weekSelinexor, 2 Days Melphalantreatment3not_yet_recruiting
NCT06529731
Interferon-γ (IFN-γ) With Donor Leukocyte Infusion to Treat Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes Post Allogeneic Hematopoietic Stem Cell Transplantationtreatment2recruiting
NCT06575296
Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplanttreatment1not_yet_recruiting
NCT06580106
Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AMLNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06616636
A Phase Ib Study of Rezatapopt in Combination with Azacitidine or Azacitidine and Venetoclax in Patients with TP53Y220C Mutant Myeloid Malignancies (Acute Myeloid Leukemia or Myelodysplastic Syndrome)treatment1not_yet_recruiting
NCT06594445
HM2023-05: GTB-3650 Trike for High Risk MDS and R/R AMLNo drug interventionstreatment1not_yet_recruiting
NCT06598969
TMLI Plus Chemotherapy in High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemiaother2not_yet_recruiting
NCT06599762
Evaluation of Tranexamic Acid in Myelodysplastic Syndromes and Acute Myeloid LeukemiatreatmentNot Availablenot_yet_recruiting
NCT06602323
TMLI/Fludarabine/Melphalan Conditioning for Allogeneic Transplantation in High-risk Myelodysplastic Syndrome or Acute Myeloid Leukemia.No drug interventionstreatment2not_yet_recruiting
NCT01141543
Feasibility and Efficiency Study of Leukemic Cell Mobilization With Plerixafor InjectionNot AvailableNot Availablecompleted
NCT03977103
Irradiation-based Myeloablative Conditioning Followed by Treg/Tcon Immunotherapy in HSCTNo drug interventionstreatment2unknown_status
NCT03063203
Single Agent Decitabine in TP53 Mutated Relapsed/Refractory Acute Myeloid Leukemiatreatment2terminated
NCT00159003
Analysis of Genetic Factors Related to Predisposition and Prognosis of Hematological Malignancies in IsraelNo drug interventionsNot AvailableNot Availablecompleted
NCT05260203
MargheRITA (Remote Intelligence for Therapeutic Adherence)No drug interventionssupportive_careNot Availablecompleted
NCT06006403
Safety and Efficacy of CD123-targeted CAR-NK for Relapsed/Refractory Acute Myeloid Leukemia or Blastic Plasmacytoid Dendritic Cell Neoplasmtreatment1 / 2recruiting
NCT05732103
A Study of CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic SyndromesNo drug interventionstreatment1 / 2recruiting
NCT05212103
PET Imaging of Cancer Patients Using 68Ga-DOTA-Siglec-9No drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT02474290
Sorafenib for Prophylaxis of Leukemia Relapse in Allo-HSCT Recipients With FLT3-ITD Positive AMLtreatment2 / 3completed
NCT06285890
Phase I Study of HC-7366 With Azacitidine and Venetoclax for Acute Myeloid Leukemiatreatment1recruiting
NCT04836390
Donor-Derived Ex-Vivo Expanded Natural Killer Cell Infusions in Children and Young Adults With High Risk Acute Myeloid Leukemia Receiving Myeloablative HLA-Haploidentical Hematopoietic Cell Transplanttreatment2enrolling_by_invitation
NCT00093990
Tipifarnib Versus Best Supportive Care in the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML)treatment3completed
NCT02864290
A Study to Evaluate Escalating Doses of ASP1235 (AGS62P1) Given as Monotherapy in Subjects With Acute Myeloid Leukemia (AML)No drug interventionstreatment1terminated
NCT03744390
IDH2 (AG 221) Inhibitor in Patients With IDH2 Mutated Myelodysplastic Syndrometreatment2active_not_recruiting
NCT05774990
Study Protocol: Study on Incidence and Risk Factors of Mold Infections in Children During Leukemia TreatmentNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04946890
A Study of MRX2843 in Subjects With Relapsed/Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1 / 2not_yet_recruiting
NCT00522990
Study to Assess the Safety of Escalating Doses of AT9283, in Patients With Leukemiastreatment1 / 2terminated
NCT01720264
Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplanttreatment2completed
NCT04086264
IMGN632 as Monotherapy or With Venetoclax and/or Azacitidine for Participants With CD123-Positive Acute Myeloid Leukemiatreatment1 / 2active_not_recruiting
NCT05330364
Study of Chidamide Combined With Cladribine in Refractory/Relapsed Acute Myeloid Leukemiatreatment2unknown_status
NCT03912064
A Phase 1 Trial of CD25/Treg-depleted DLI Plus Ipilimumab for Myeloid Disease Relapse After Matched-HCTtreatment1active_not_recruiting
NCT03603964
Guadecitabine Extension Studytreatment2terminated
NCT00300664
A Randomized Trial of Human Growth Hormone (hGH) vs Placebo in Intensively Treated Haemato-Oncology Patients.Not Available2 / 3completed
NCT04471064
A Study of XY0206 Tablets in Patients With Relapsed / Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1recruiting
NCT02310321
A Study of ASP2215 in Combination With Induction and Consolidation Chemotherapy in Patients With Newly Diagnosed Acute Myeloid Leukemia.treatment1 / 2active_not_recruiting
NCT02632721
A Trial to Find and Investigate a Safe Dose of BI 836858 in Combination With Decitabine for Patients With Acute Myeloid Leukemia (AML)treatment1 / 2completed
NCT02413021
The Effect of Deferasirox on Response Rate of Acute Leukemia Patients Not Treated by Standard Chemotherapy Regimenstreatment1unknown_status
NCT00620321
A Study of LY2181308 Sodium in Patients With Relapsed or Refractory Acute Myeloid Leukemiatreatment2completed
NCT03433521
Observational Study of Spatio-Temporal Patterns of New Cases of Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT00559221
FLAG+Ida With G-CSF Priming for Patients Younger Than 60 Years With Resistant AMLNo drug interventionstreatment2unknown_status
NCT03326921
HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplanttreatment1suspended
NCT02461121
HLA-mismatched MST vs HLA-matched NST for AML in Intermediate-risktreatment3completed
NCT02312102
Velcade and Lenalidomide in Patients With Relapsed AML and MDS After Allogeneic Stem Cell Transplantationtreatment1active_not_recruiting
NCT03349502
MG4101 for Refractory or Relapsed AMLtreatment2completed
NCT05218902
A Study of Azacitidine in Participants With International Prognostic Scoring System (IPSS) Intermediate-2 and High-risk Myelodysplastic Syndromes (MDS), or Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML)No drug interventionsNot AvailableNot Availablecompleted
NCT03027102
Study of Allogeneic Double Negative T Cells (DNT-UHN-1) in Patients With High Risk Acute Myeloid LeukemiaNo drug interventionstreatment1active_not_recruiting
NCT01534702
Dose Escalation of Clofarabine in Combination With Cytarabine and Idarubicin as Induction Therapy in High Risk AMLtreatment1 / 2unknown_status
NCT02997202
A Trial of the FMS-like Tyrosine Kinase 3 (FLT3) Inhibitor Gilteritinib Administered as Maintenance Therapy Following Allogeneic Transplant for Patients With FLT3/Internal Tandem Duplication (ITD) Acute Myeloid Leukemia (AML)treatment3completed
NCT04033302
Multi-CAR T Cell Therapy Targeting CD7-positive MalignanciesNo drug interventionstreatment1 / 2unknown_status
NCT04168502
Gemtuzumab Chemotherapy MRD Levels; Glasdegib Post-transplant, Adult Untreated, de Novo, Fav Interm Risk AMLtreatment3recruiting
NCT00583102
Dose Escalation Phase I/II Study of Lovastatin With High-Dose Cytarabine for Refractory or Relapsed AMLtreatment1 / 2terminated
NCT02641002
A Study of CC-90002 in Subjects With Acute Myeloid Leukemia (AML) and High-risk Myelodysplastic Syndrome (MDS)No drug interventionstreatment1terminated
NCT05246384
Study to Evaluate the Safety, Pharmacokinetics and Clinical Activity of RP7214 in Combination With Azacitidine in Patients With Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia and Acute Myeloid LeukemiaNo drug interventionstreatment1 / 2withdrawn
NCT05342584
Venetoclax Plus Intensive Chemotherapy in AML and Advanced MDStreatment1recruiting
NCT04884984
Anti-CLL1 CAR T-cell Therapy in CLL1 Positive Relapsed/Refractory Acute Myeloid Leukemia (AML)No drug interventionstreatment1 / 2recruiting
NCT00273884
Amonafide in Combination With Cytarabine in Secondary AMLtreatment2completed
NCT03451084
A Dose Optimisation Study of ASLAN003 in Acute Myeloid Leukemiatreatment2completed
NCT03298984
Ph I Study of Alvocidib and Cytarabine/Daunorubicin (7+3) in Patients With Newly Diagnosed Acute Myeloid Leukemia (AML).treatment1completed
NCT02326584
A Safety Study of SGN-CD33A in Combination With Standard-of-care in Patients With AMLtreatment1completed
NCT03795779
CLL1-CD33 cCAR in Patients With Relapsed and/or Refractory, High Risk Hematologic Malignanciestreatment0unknown_status
NCT03915379
A Study of JNJ-67571244 in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)No drug interventionstreatment1completed
NCT05654779
CLL-1/CD33 Targeted LCAR-AMDR Cells in Patients With Relapsed or Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1terminated
NCT01843179
Sulindac for Patients With AMLtreatment2withdrawn
NCT01606579
Safety and Efficacy Study of PRI-724 in Subjects With Advanced Myeloid Malignanciestreatment1 / 2completed
NCT04092179
Study of Enasidenib and Venetoclax in IDH2-Mutated Blood Cancerstreatment1 / 2terminated
NCT04262843
Total Marrow and Lymphoid Irradiation as Conditioning Regimen Before Hematopoietic Cell Transplantation in Patients With Myelodysplastic Syndrome or Acute Leukemiatreatment2recruiting
NCT00880243
Effect of Priming During Induction and Consolidations in Younger Acute Myeloid Leukemia (AML)treatment3completed
NCT04369287
Prevalence and Clinical Effect of IDH1/2 Mutations in Patients With Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01687387
Efficacy Study of Anti-KIR Monoclonal Antibody as Maintenance Treatment in Acute Myeloid Leukemia (EFFIKIR)treatment2completed
NCT04500587
Phase 1 First in Human Study of ZN-d5 as a Single AgentNo drug interventionstreatment1recruiting
NCT01960387
Phase II Clofarabine and Cytarabine for Newly Diagnosed Acute Myeloid Leukemiatreatment2terminated
NCT01908387
Phase 1 Study of CC-486 in Japanese Subjects With Hematological Neoplasmstreatment1terminated
NCT04191187
Reduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignanciestreatment2active_not_recruiting
NCT05319587
Study of Liposomal Annamycin in Combination With Cytarabine for the Treatment of Subjects With Acute Myeloid Leukemia (AML)treatment1 / 2recruiting
NCT04150887
Cusatuzumab in Combination With Background Therapy for the Treatment of Participants With Acute Myeloid Leukemiatreatment1active_not_recruiting
NCT03429387
PET/CT and Bacterial/Fungal PCR in High Risk Febrile NeutropeniaNo drug interventionsdiagnosticNot Availablecompleted
NCT04284787
BLAST MRD AML-2: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 2- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Azacitidine and Venetoclax as Frontline Therapy in Unfit Patients With Acute Myeloid Leukemiatreatment2active_not_recruiting
NCT05521087
A Study of JNJ-75276617 in Combination With Conventional Chemotherapy for Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemiastreatment1withdrawn
NCT01385787
MRD Testing Before and After Hematopoietic Cell Transplantation for Pediatric Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT02658487
Vosaroxin and Infusional Cytarabine in Treating Patients With Untreated Acute Myeloid Leukemiatreatment2active_not_recruiting
NCT00990587
Study Evaluating the Tolerance and Biologic Activity of Oral Ciclopirox Olamine in Patients With Relapsed or Refractory Hematologic Malignancytreatment1completed
NCT00590187
Efficacy Study of Oral Sapacitabine to Treat Acute Myeloid Leukemia in Elderly Patientstreatment2completed
NCT00528333
A Study of Lintuzumab (SGN-33) in Combination With Low Dose Cytarabine in Patients 60+ Years With AMLtreatment2completed
NCT04195633
Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignanciestreatment2recruiting
NCT03796533
Pharmacokinetics Variability of Posaconazole (PCZ) and Its Glucuronide Metabolite During Induction and Consolidation Treatments in Patients With Acute Myeloid Leukemia (AML): a Covariate Analysis With the Tablets Formulation and Evaluation of the Potential Risk of Hepatotoxicityhealth_services_researchNot Availableunknown_status
NCT02275533
Testing Nivolumab to Prevent Disease From Coming Back After Treatment in Patients With Acute Myeloid Leukemia, REMAIN Trialtreatment2active_not_recruiting
NCT02016833
Development of Immunological Assays for the Evaluation of Tumor Antigen Specific ImmunityNo drug interventionsNot AvailableNot Availablecompleted
NCT04902833
Acquired Pyruvate Kinase Deficiency In Clonal Myeloid NeoplasmsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00593554
Phase 2 Haplotype Mismatched HSCT in Patients With Hematological Malignanciestreatment2terminated
NCT03110354
DS-3201b for Acute Myelogenous Leukemia (AML) or Acute Lymphocytic Leukemia (ALL)No drug interventionstreatment1terminated
NCT03417154
Nivolumab and Oral Cyclophosphamide for R/R AML and HIgh Risk MDStreatment2completed
NCT04708054
Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDStreatment2recruiting
NCT03268954
Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine as First-Line Treatment for Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML), or Low-Blast Acute Myelogenous Leukemia (AML)treatment3active_not_recruiting
NCT03896854
CART-19 T Cell in CD19 Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)treatment1 / 2recruiting
NCT02999854
Safety and Efficacy of ATIR101 as Adjunctive Treatment to Blood Stem Cell Transplantation From a Haploidentical Family Donor Compared to Post-transplant Cyclophosphamide in Patients With Blood Cancerprevention3terminated
NCT01025154
Clofarabine, Idarubicin, and Cytarabine Combination in Acute Myeloid Leukemia (AML) Inductiontreatment2completed
NCT02276651
Observational Trial of a Therapeutic Platelet Transfusion RegimenNo drug interventionsNot AvailableNot Availableterminated
NCT03672851
Study Evaluating Safety and Efficacy of CAR-T Cells Targeting CD123 in Patients With Acute LeukemiaNo drug interventionstreatment1terminated
NCT02891551
An Observational Post Authorisation Study to Evaluate Safety and Efficacy in Patients Receiving Azacitidine in Daily Clinical Practice in the NetherlandsNo drug interventionsNot AvailableNot Availablecompleted
NCT05001451
Study of GDX012 in Patients With MRD Positive AMLtreatment1terminated
NCT02680951
Dasatinib in Combination With Chemotherapy for Relapsed or Refractory Core Binding Factor Acute Myeloid Leukemiatreatment1withdrawn
NCT03549351
Evaluation of Measurable Residual Disease in Patients With Acute Myeloid Leukemia as Surrogate Endpoint for SurvivalNo drug interventionsNot AvailableNot Availableterminated
NCT01785953
Conventional and Experimental Chemotherapy With Allogeneic Transplant in Young Patients With Acute Myeloid LeukaemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT02668653
Quizartinib With Standard of Care Chemotherapy and as Continuation Therapy in Patients With Newly Diagnosed FLT3-ITD (+) Acute Myeloid Leukemia (AML)treatment3completed
NCT02954653
A Study Of PF-06747143, As Single Agent Or In Combination With Standard Chemotherapy In Adult Patients With Acute Myeloid Leukemiatreatment1terminated
NCT02485353
Study of Vosaroxin and Cytarabine for the Treatment of Adults 60 Years of Age or Older With Previously Untreated AMLtreatmentNot Availableterminated
NCT03922477
A Study Evaluating the Safety and Pharmacokinetics of Atezolizumab Administered in Combination With Hu5F9-G4 to Patients With Relapsed and/or Refractory Acute Myeloid Leukemiatreatment1terminated
NCT02870777
MRD-directed Therapy for Low-risk and Intermediate-risk AML.No drug interventionstreatment2 / 3completed
NCT02610777
An Efficacy and Safety Study of Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine in Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML) and Low-Blast Acute Myelogenous Leukemia (AML)treatment2completed
NCT00807677
A Phase 1 Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignanciestreatment1completed
NCT01074047
Study of Vidaza Versus Conventional Care Regimens for the Treatment of Acute Myeloid Leukemia (AML)treatment3completed
NCT05672147
CD33-CAR T Cell Therapy for the Treatment of Recurrent or Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1recruiting
NCT02799147
GVHD Prophylaxis With Post-transplantation Bendamustine in Refractory Leukemiatreatment1 / 2completed
NCT04195945
CPX-351 or CLAG-M Regimen for the Treatment of Acute Myeloid Leukemia or Other High-Grade Myeloid Neoplasms in Medically Less-Fit Patientstreatment2recruiting
NCT04914845
KPT-9274 in Patients With Relapsed and Refractory Acute Myeloid Leukemiatreatment1recruiting
NCT04571645
Dociparstat in Combination With Standard Chemotherapy for the Treatment of Acute Myeloid Leukemiatreatment3terminated
NCT03655145
HLA 10/10 Matched Unrelated Donor vs Haploidentical Allogenic Hematopoietic Stem Cell TransplantationNo drug interventionstreatment3unknown_status
NCT00875745
Combination of Sorafenib and Vorinostat in Poor-risk Acute Myelogenous Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)treatment1completed
NCT00916045
Pilot Study of Unrelated Cord Blood Transplantationtreatment2terminated
NCT03449745
Immune Checkpoint Receptors in AML-Leukemic Initiating CellsNo drug interventionsNot AvailableNot Availablecompleted
NCT04518345
TP-0903 for the Treatment of FLT3 Mutated Acute Myeloid Leukemiatreatment0completed
NCT01065545
The Role of Maintenance Oral Clofarabine in Older Adults With Acute Myeloid Leukemiatreatment1withdrawn
NCT03760445
HDM201 Added to CT in R/R or Newly Diagnosed AMLtreatment1 / 2withdrawn
NCT01170598
Acute Myeloid Leukaemia (AML) Patients Undergoing Induction ChemotherapyNo drug interventionssupportive_care2completed
NCT04687098
Risk-adapted Therapy for Primary Acute Myeloid Leukemiatreatment2completed
NCT00780598
Safety and Anti-Disease Activity of Oral Tosedostat (CHR-2797) in Elderly Subjects With Refractory or Relapsed AMLtreatment2completed
NCT00927498
A Randomized Study of Gemtuzumab Ozogamicin (GO) With Daunorubicine and Cytarabine in Untreated Acute Myeloid Leukemia (AML) Aged of 50-70 Years Oldtreatment3completed
NCT01823198
Donor Natural Killer Cells and Donor Stem Cell Transplant in Treating Patients With High Risk Myeloid Malignanciestreatment1 / 2completed
NCT04910698
Efficacy of Antibiotic Short Course for Bloodstream Infections in Acute Myeloid Leukemia Patients With Febrile NeutropeniaNo drug interventionsNot AvailableNot Availablecompleted
NCT06429098
Study of A Venetoclax-based, Anthracycline-free Regimen in Newly Diagnosed CBFβ::MYH11(+) AMLtreatment2recruiting
NCT00329498
L-Ascorbic Acid Depletion to Treat Acute Myeloid Leukemia and Myelodysplastic Syndromestreatment2suspended
NCT05333705
Donor Immune Cell Therapy for Acute Myeloid Leukemiatreatment1unknown_status
NCT01662505
Volasertib in Japanese Patients With Acute Myeloid Leukemia (AML)treatment1completed
NCT04964505
Uproleselan, Azacitidine, and Venetoclax for the Treatment of Treatment Naive Acute Myeloid Leukemiatreatment1active_not_recruiting
NCT04188405
Decitabine, Venetoclax, and Ponatinib for the Treatment of Philadelphia Chromosome-Positive Acute Myeloid Leukemia or Myeloid Blast Phase or Accelerated Phase Chronic Myelogenous Leukemiatreatment2active_not_recruiting
NCT04543305
A Study of PRT1419 in Patients With Relapsed/Refractory Hematologic MalignanciesNo drug interventionstreatment1completed
NCT01810705
GRASPA Treatment for Patients With Acute Myeloblastic Leukemiatreatment2completed
NCT03988205
Patients Receiving Induction With Liposomal Daunorubicin and Cytarabine (CPX-351) for Acute Myeloid Leukemiatreatment4terminated
NCT03814005
A Study of Pevonedistat in People With Blood Cancers or Solid Tumors With Kidney or Liver Problemsother1completed
NCT03333005
Safety and Pharmacokinetics of Intravenous and Oral APX001 in Patients With Acute Myeloid Leukemia (AML) and Neutropeniaother1completed
NCT05031897
Reduced-Intensity Conditioning for the Prevention of Treatment-Related Mortality in Patients Who Undergo a Hematopoietic Stem Cell Transplanttreatment2recruiting
NCT00546897
Lenalidomide in Older Patients With Acute Myeloid Leukemia Without Chromosome 5q Abnormalitiestreatment2completed
NCT02226497
Telemonitoring Device in Managing Outpatient Care of Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia After Intensive ChemotherapyNo drug interventionsdevice_feasibilityNot Availableterminated
NCT02156297
Sorafenib to Treat FLT3-ITD AMLNo drug interventionsNot AvailableNot Availableunknown_status
NCT02971397
Cytarabine and Daunorubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment1completed
NCT02765997
StemRegenin-1 Expanded vs Unexpanded UCB for High Risk Heme MalignanciesNo drug interventionstreatment2withdrawn
NCT04801797
Venetoclax + Azacitidine vs. Induction Chemotherapy in AMLtreatment2recruiting
NCT01751997
Family-mismatched/Haploidentical Donors Versus Matched Unrelated DonorsNo drug interventionstreatment2 / 3completed
NCT02845297
Study of Azacitidine in Combination With Pembrolizumab in R/R AML Patients and in Newly Diagnosed Older Patientstreatment2completed
NCT02779283
Personalized Kinase Inhibitor Therapy Combined With Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and Acute Lymphoblastic Leukemiatreatment1completed
NCT01055483
A Phase Ib, Open-label, Multi-center Dose-finding Study of Oral Panobinostat (LBH589) in Combination With Ara-C and Mitoxantrone as Salvage Therapy for Refractory or Relapsed Acute Myeloid Leukemiatreatment1completed
NCT06221683
Clinical Study of Induction Therapy Options Based on Molecular Subtyping and MRD in Children and Adolescents With AMLtreatment2recruiting
NCT04167683
Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell TransplantNo drug interventionsNot AvailableNot Availablerecruiting
NCT01266083
WT-1 Analog Peptide Vaccine in Acute Myeloid Leukemia (AML) or Acute Lymphoblastic Leukemia (ALL)No drug interventionstreatment2completed
NCT03530683
A Clinical Trial to Learn About the Study Medicine Called Maplirpacept (PF-07901801), Alone and When Used in Combination With Other Medicines to Treat Participants With Advanced Hematological Malignancies, Including Lymphoma, Leukemia and Multiple Myelomatreatment1terminated
NCT03955783
Venetoclax and Selinexor in Treating Patients With Relapsed or Refractory High Risk Hematologic Malignanciestreatment1active_not_recruiting
NCT06355583
Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) TrialNo drug interventionsprevention2not_yet_recruiting
NCT03719183
Comparison of Diagnostic Yield Among M-FISH, FISH Probe Panel and Conventional Cytogenetic Analysis in AMLNo drug interventionsNot AvailableNot Availablecompleted
NCT06514261
Testing the Combination of an Anti-Cancer Drug, Iadademstat, With Other Anti-Cancer Drugs (Venetoclax and Azacitidine) for Treating AMLtreatment1not_yet_recruiting
NCT03927261
PRGN-3006 Adoptive Cellular Therapy for CD33-Positive Relapsed or Refractory AML, MRD Positive AML or Higher Risk MDStreatment1active_not_recruiting
NCT01985061
Evaluation of 3 Different Doses of IV Busulfantreatment2unknown_status
NCT00096161
Pentostatin and Lymphocyte Infusion in Preventing Graft Rejection in Patients Who Have Undergone Donor Stem Cell Transplanttreatment2completed
NCT04802161
Comparing the Addition of an Anti-Cancer Drug, Pomalidomide, to the Usual Chemotherapy Treatment (Daunorubicin and Cytarabine Liposome) in Newly Diagnosed Acute Myeloid Leukemia With Myelodysplastic Syndrome-Related Changestreatment2suspended
NCT03797261
A Study of Venetoclax and AMG 176 in Patients With Relapsed/Refractory Hematologic Malignanciestreatment1terminated
NCT01830361
Trial to Assess the Efficacy of Midostaurin (PKC412) in Patients With c-KIT or FLT3-ITD Mutated t(8;21) AMLtreatment2completed
NCT02141828
A Phase 1 Dose Escalation and Expanded Cohort Study of EPZ-5676 in the Treatment of Pediatric Patients With Relapsed/Refractory Leukemias Bearing a Rearrangement of the MLL Genetreatment1completed
NCT01853228
A Study of Decitabine (DACOGEN) in Sequential Administration With Cytarabine in Children With Relapsed or Refractory Acute Myeloid Leukemiatreatment1 / 2terminated
NCT00067028
Clofarabine Combinations in Relapsed/Refractory Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS) and Myeloid Blast Phase Chronic Myeloid Leukemia (CML)treatment2completed
NCT03106428
A Multiple Ascending Dose Study of MEDI7247 in Patients With Selected Relapsed/Refractory Hematological MalignanciesNo drug interventionstreatment1completed
NCT04867928
Venetoclax and Azacitidine for the Management of Molecular Relapse/Progression in Adult NPM1-mutated Acute Myeloid Leukemiatreatment2recruiting
NCT04589728
Prospective and Retrospective Observational Evaluation of Real World Outcome of Unfit AML Patients Treated With the Combination Venetoclax Plus Hypomethylating Agents, Under the Italian Law No.648/96Not AvailableNot Availablerecruiting
NCT05260528
CPX-351 vs Intensive Chemotherapy in Patients With de Novo Intermediate or Adverse Risk AML Stratified by Genomicstreatment2recruiting
NCT01390311
Azacitidine After Chemotherapy and Donor Lymphocyte Infusion in Patients With Relapsed Acute Myeloid Leukemia or Myelodysplastic Syndrome Previously Treated With Donor Stem Cell Transplanttreatment1completed
NCT02715011
Dose Escalation Study of JNJ-63709178, a Humanized CD123 x CD3 DuoBody in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML)No drug interventionstreatment1completed
NCT03108911
Gluten Free Diet in Diminishing Side Effects Patients With Acute Myeloid Leukemia Undergoing Induction ChemotherapyNo drug interventionssupportive_care2terminated
NCT00451711
Intermittent Liposomal Amphotericin B Primary Prophylaxisprevention2unknown_status
NCT03393611
CPX-351 Salvage Therapy Followed by Haplo-Cord Transplant for Relapsed/Refractory Leukemia or Myelodysplastic Syndrometreatment1completed
NCT00658411
Deferoxamine for Iron Overload Before Allogeneic Stem Cell TransplantationpreventionNot Availableterminated
NCT05140811
A Study of IMM01 Combined With Azacitidine in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrometreatment1 / 2recruiting
NCT00915811
Pilot Study of Reduced Intensity Haematopoietic Stem Cell Transplantation in Patients With Poor Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukaemia (AML) Utilising Conditioning With Fludarabine, Busulphan and Thymoglobulintreatment2terminated
NCT02007811
Open-label Clinical Trial to Investigate the Safety and Tolerability of Allogeneic B-cell Concentrates for Immune Reconstitution After Allogeneic Stem Cell Transplantation Measured as Response to a Antedated Single VaccinationNo drug interventionstreatment1 / 2unknown_status
NCT04473911
Haplo Peripheral Blood Sct In GVHD Preventiontreatment1active_not_recruiting
NCT05272293
Immunotherapy With ex Vivo Expanded Haploidentical Natural Killer Cells for Children/Young Adults With AMLNo drug interventionstreatment1 / 2recruiting
NCT03404193
Venetoclax and Decitabine in Treating Participants With Relapsed/Refractory Acute Myeloid Leukemia or Relapsed High-Risk Myelodysplastic Syndrometreatment2active_not_recruiting
NCT03284593
Prognostic Factors and the Impact of Various Management of Acute Myeloid Leukemia in Real Life ConditionNot AvailableNot Availableactive_not_recruiting
NCT02293993
Phase 1 Study of SGI-110 in Patients With Acute Myeloid Leukemiatreatment1completed
NCT04358393
A Study of APG-115 Alone or Combined With Azacitidine in Patients With AML, CMML, or MDStreatment1 / 2recruiting
NCT04671693
A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors.No drug interventionspreventionNot Availablerecruiting
NCT05909293
Clinical Study Protocol of Maintenance Therapy With Venetoclax in Elderly Patients With AML in First Complete RemissiontreatmentNot Availablerecruiting
NCT01965171
Transfusional Iron Overload Among Leukemia SurvivorsNo drug interventionsNot AvailableNot Availablecompleted
NCT04537871
Cardiovascular Reserve Evaluation in Survivors of Transplant, CREST StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05501171
Psychological Mobile App for Patients With AMLNo drug interventionssupportive_careNot Availableterminated
NCT02164071
Validation of a Comprehensive Health Status Assessment Scale in Elderly Patients (≥ 65 Years) With Hematological MalignanciesNo drug interventionsNot AvailableNot Availablecompleted
NCT04221971
NK Cell Infusion for Patients With Acute Myeloid Leukemiatreatment1unknown_status
NCT02619071
ChEmo-Genomics Based Treatment of Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT03113071
Safety and Activity of Digoxin With Decitabine in Adult AML and MDStreatment1 / 2terminated
NCT02856178
Study on Safety and Pharmacokinetics of Intravenous F901318 for Fungal Prophylaxis in AML Patientsprevention1 / 2withdrawn
NCT00150878
Standard vs. Reduced-Intensity Conditioning in Patients With Acute Myeloid Leukemia in First RemissionNo drug interventionstreatment3terminated
NCT02891278
Sertraline and Cytosine Arabinoside in Adults With Relapsed and Refractory AMLtreatment1completed
NCT02767388
Electrophysiological Biomarkers of Chemotherapy-related Cognitive Impairment and RecoveryNo drug interventionsNot AvailableNot Availablecompleted
NCT06118788
Phase I Clinical Study: BG1805 Injection in the Treatment of Relapsed or Refractory Acute Myeloid Leukemiatreatment1 / 2recruiting
NCT00952588
Study to Investigate the Efficacy, Safety and Tolerability of AZD1152 Alone and in Combination With Low Dose Cytosine Arabinoside (LDAC)in Acute Myeloid Leukaemia (AML) Patientstreatment2 / 3completed
NCT03041688
Testing a New Chemotherapy Drug, KRT-232 (AMG-232) in Combination With Decitabine and Venetoclax in Patients With Acute Myeloid Leukemiatreatment1active_not_recruiting
NCT03622788
Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplanttreatment1 / 2recruiting
NCT04920188
Development and Application of a Novel Digital Array PCR for Acute Myeloid Leukemia (AML)No drug interventionsNot AvailableNot Availableterminated
NCT00719888
Umbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With Hematologic Diseasetreatment2active_not_recruiting
NCT01295307
Clofarabine Salvage Therapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)treatment2completed
NCT04070807
Italian Observational Study of Patients With Acute Myeloid Leukemia Treated With Small Molecule Inhibiting BCL-2No drug interventionsNot AvailableNot Availableunknown_status
NCT05023707
Anti-FLT3 CAR T-cell Therapy in FLT3 Positive Relapsed/Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1 / 2recruiting
NCT03661307
Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrometreatment1 / 2recruiting
NCT02176109
Metabolism Des LAMNo drug interventionsNot AvailableNot Availableunknown_status
NCT00488709
Fludarabine, Cytarabine, Topotecan in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemiatreatment4completed
NCT00852709
Phase I Dose-Escalation Trial of Clofarabine Followed by Escalating Doses of Fractionated Cyclophosphamide in Children With Relapsed or Refractory Acute Leukemiastreatment1terminated
NCT03836209
Gilteritinib vs Midostaurin in FLT3 Mutated Acute Myeloid Leukemiatreatment2active_not_recruiting
NCT04027309
A Study of Gilteritinib Versus Midostaurin in Combination With Induction and Consolidation Therapy Followed by One-year Maintenance in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndromes With Excess Blasts-2 With FLT3 Mutations Eligible for Intensive Chemotherapytreatment3active_not_recruiting
NCT01636609
Tosedostat and Cytarabine or Azacitidine in Treating Older Participants With Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrometreatment1terminated
NCT06152809
CIML NK Cells With Venetoclax for AMLtreatment1active_not_recruiting
NCT04044209
A Study of the IDH1 Inhibitor AG-120 in Combination With the Checkpoint Blockade Inhibitor, Nivolumab, for Patients With IDH1 Mutated Relapsed/Refractory AML and High Risk MDStreatment2withdrawn
NCT04156256
CD123-CD33 cCAR in Patients With Relapsed and/or Refractory, High Risk Hematologic MalignanciesNo drug interventionstreatment0unknown_status
NCT03755856
Long-term Outcomes for Acute Myeloid Leukemia PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT05982756
Bortezomib Combined With DAG Regimen in the Treatment of Refractory/Relapsed AMLtreatment1recruiting
NCT05883956
A Study Comparing Treatment Preference Between Oral Decitabine/Cedazuridine and Azacitidine in Myelodysplastic Syndrome, Low-Blast Acute Myeloid Leukemia, or Chronic Myelomonocytic Leukemiatreatment3active_not_recruiting
NCT05662956
A Clinical Study of VA-CAG as Induction Therapy in Newly Diagnosed AML Patientstreatment1 / 2recruiting
NCT05304156
Single-cell Dynamic Profiling in Adults With Newly Diagnosed Acute Myeloid Leukemia Treated With Intensive Chemotherapy. A THEMA Study"No drug interventionsNot AvailableNot Availablerecruiting
NCT00804856
Phase I/IIa Trial to Investigate BI 6727 (Volasertib) as Monotherapy or in Combination With Cytarabine in Acute Myeloid Leukaemiatreatment2completed
NCT05593185
Expanded Access Program (EAP) for Galinpepimut-S (GPS) in Patients Diagnosed With AML or MDSNot AvailableNot Availableavailable
NCT05248685
Optimized Dual CD33/CLL1 CAR T Cells in Subjects With Refractory or Relapsed Acute Myeloid LeukemiaNo drug interventionstreatment1unknown_status
NCT04243785
A Study of BTX-A51 in People With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrometreatment1recruiting
NCT04980885
A Trial of AK117 (Anti-CD47 Antibody) in Patients With Acute Myeloid Leukemiatreatment1 / 2recruiting
NCT03530085
Dec+Flu+Bu Conditioning Regimen for Elderly AML in CR Undergoing Allo-HSCTtreatment2 / 3unknown_status
NCT03234985
Study of Intracellular Nucleotide Pools Determination as Biomarker of the Efficacy of the Induction Treatment in Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT05941585
Mitoxantrone Hydrochloride Liposome Combined With Chemotherapy in Untreated de Novo Acute Myeloid LeukemiatreatmentNot Availablerecruiting
NCT03661515
Selinexor (KPT-330) Plus FLAG-Ida for the Treatment of Relapsing/Refractory AMLtreatment1completed
NCT02921815
A Study to Analyze the Occurrence of Transformation From Myelodysplastic Syndrome to Acute Myeloid Leukemia in Patients With Myelodysplastic Syndrome Who Received Revlimid® 5 mg Capsules and Who Are Continuing or no Longer Continuing Revlimid TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT03844815
Study of Venetoclax in Combination With Decitabine in Subjects With Acute Myeloid Leukemiatreatment1active_not_recruiting
NCT03181815
Cladribine in Combination With CAG in Patients With Refractory/Relapsed Acute Myeloid Leukemiatreatment2unknown_status
NCT04968015
Venetoclax + Cytarabine Versus Idarubicin + Cytarabine : Efficacity Assessment as Post-remission Therapy to Elderly Patients With Acute Myeloid Leukemia in First Remissiontreatment2active_not_recruiting
NCT02117115
Abdominal CT to Predict the Risk of Acute Graft-versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantationscreening0completed
NCT02282215
Safety and Efficacy of Human Myeloid Progenitor Cells (CLT-008) During Chemotherapy for Acute Myeloid Leukemiasupportive_care2completed
NCT05215015
Study of Anti-CD33/CLL1 CAR-NK in Acute Myeloid Leukemiatreatment0unknown_status
NCT01054937
Single Dose Study With 4SC-203 in Healthy Volunteerstreatment1completed
NCT04038437
A Trial of CPX-351 Lower Intensity Therapy (LIT) Plus Venetoclax as First Line Treatment for Subjects With AMLtreatment1completed
NCT03760237
Cardiovascular Function in Acute LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT03696537
IMRT-TMI With Fludarabine as Myeloablative Conditioning for Allogeneic HSCTtreatment1terminated
NCT04327037
Safety of Expanded Haploidentical Natural Killer Cells for Leukemiatreatment1completed
NCT06313437
Revumenib in Combination With 7+3 + Midostaurin in AMLtreatment1not_yet_recruiting
NCT02250937
Venetoclax and Sequential Busulfan, Cladribine, and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrometreatment2active_not_recruiting
NCT00590837
Adding Lomustine to Chemotherapy in Older Patients With Acute Myelogenous Leukemia (AML), and Allogeneic Transplantation for Patients From 60 to 65 Years Oldtreatment3completed
NCT03194932
Study of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous Lineagetreatment1completed
NCT05659732
A Study of PEP07 (Checkpoint Kinase 1 Inhibitor) in Patients With Advanced CancerNo drug interventionstreatment1recruiting
NCT04484532
Evaluation of Antibody Response to High-Dose Seasonal Influenza Vaccination in Patients With Myeloid Malignancy Receiving Chemotherapy and Healthy Volunteerssupportive_care0completed
NCT02682732
Molecular Imaging to Capture Disease Heterogeneity in Acute Myeloid LeukemiaNo drug interventionsdiagnosticNot Availableunknown_status
NCT03769532
MRD-guided Treatment in NPM1mut AML Patientstreatment2recruiting
NCT02773732
Clinical Trial of Oral Ciprofloxacin and Etoposide in Subjects With Resistant Acute Myeloid Leukemia (AML)(UF-AML-CE-101)treatment1 / 2terminated
NCT05105152
PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AMLNo drug interventionstreatment1recruiting
NCT02223052
Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignanciestreatment1completed
NCT02294552
Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCTtreatment2completed
NCT05016752
Application of Nanopore Sequencing in Newly Diagnosed Acute Myeloid Leukemia Patients With Bloodstream InfectionNo drug interventionsNot AvailableNot Availableunknown_status
NCT05123352
Investigation of the Gut Microbiota in Acute Myeloid Leukemia Receiving Two Different Induction TherapiesNo drug interventionsNot AvailableNot Availableunknown_status
NCT00915252
Efficacy of 5-azacytidine Added to Standard Primary Therapy in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)treatment2completed
NCT03442452
AML Electronic Decision AidNo drug interventionssupportive_careNot Availablecompleted
NCT00689000
Safety and Anti-Disease Activity of CHR-2797 (Tosedostat) in Elderly and/or Treatment Refractory Patients With Acute Myeloid Leukemia (AML) and Multiple Myeloma (MM)treatment1 / 2completed
NCT01016600
Azacitidine and Lenalidomide for Acute Myeloid Leukemiatreatment1 / 2completed
NCT05471700
Single Arm Study of Azacitidine and Venetoclax for Treatment of Newly Diagnosed Fit Acute Myeloid Leukemia Patientstreatment1 / 2recruiting
NCT06021600
A Phase 1, Open-Label, Sequential Cross-over, Bioavailability/Bioequivalence Study to Compare the Pharmacokinetics of Oral Cladribine With the Reference Listed Drug, Intravenous Cladribinetreatment1recruiting
NCT05641259
A Study to Assess Safety and Preliminary Efficacy of LP-108 Combined With Azacitidine In Subjects With AML, MDS, CMMLtreatment1recruiting
NCT00839059
Lenalidomide In Patients With Acute Myeloid Leukemiatreatment1terminated
NCT05279859
A Study of Anti-Cancer Therapies Targeting the MAPK Pathway in Patients With Hematologic Malignanciestreatment1 / 2withdrawn
NCT04887259
Trial of LAVA-051 in Patients With Relapsed/Refractory CLL, MM, or AMLtreatment1 / 2active_not_recruiting
NCT06504459
Venetoclax in Combination With Cladribine and Cytarabine Alternating With Azacitidine Plus Venetoclax for the Treatment of Newly Diagnosed Monocytic AML and Active Signaling Mutated AMLtreatment2not_yet_recruiting
NCT05772559
Acute Myeloid Leukemia At Initial Diagnosis and/or Relapse in Children, Teenagers and Young Adults: Molecular Profiling, Multidrug Testing and MSC Interaction StudiesNo drug interventionsNot AvailableNot Availablerecruiting
NCT00143975
Gemtuzumab Ozogamicin in Combination With A-HAM in Refractory AML (GO-A-HAM)treatment2completed
NCT05583175
Venetoclax Plus RIC Regimen Allo-HSCT for Elderly Patients With High-risk Myeloid Malignanciestreatment2recruiting
NCT02412475
Epigenetic Reprogramming in Relapse AMLtreatment1terminated
NCT00778375
Clofarabine Plus Low-Dose Cytarabine Induction and Decitabine Consolidation in Frontline Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS)treatment2completed
NCT01142375
Development and Exploration of the Feasibility of Using Locally Synthesized Small Molecule Inhibitors to Treat Human Acute Leukemia CellsNo drug interventionsNot AvailableNot Availableunknown_status
NCT06034275
Study of VIP943 in Subjects With Advanced CD123+ Hematologic MalignanciesNo drug interventionstreatment1recruiting
NCT00513175
Non-Myeloablative Allogeneic Stem Cell Transplantation With Matched Unrelated Donors for Treatment of Hematologic Malignancies, Renal Cell Carcinoma, and Aplastic AnemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT04257175
CAR-T CD19 for Acute Myelogenous Leukemia With t 8:21 and CD19 Expressiontreatment2 / 3recruiting
NCT03383575
Azacitidine and Enasidenib in Treating Patients With IDH2-Mutant Myelodysplastic Syndrometreatment2recruiting
NCT02763475
NK Cells as Consolidation Therapy of Acute Myeloid Leukemia in Children/Adolescentstreatment2completed
NCT05968170
TCRαβ/CD19 Depletion of Stem Cell Grafts for TransplantNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05933070
A Phase I Open-Label Dose Escalation Study of Intravenous INKmune In Patients With MDS or AMLNo drug interventionstreatment1terminated
NCT06128070
Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndromeprevention2recruiting
NCT06429670
Real World Use of Azacitidine and Venetoclax in Acute Myeloid Leukemia in Frontline and Relapse/RefractoryNo drug interventionsNot AvailableNot Availablecompleted
NCT01475370
Study of OCV-501 in Patients With Acute Myeloid Leukemia (AML) (Extension From Study 311-10-001)No drug interventionstreatment1completed
NCT02057770
Allogeneic or Haploidentical Stem Cell Transplant Followed By High-Dose Cyclophosphamide in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemiatreatment1terminated
NCT01976442
Use of Saline-Washed Platelet and Red Cell Transfusions in Adult Acute LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT01015742
Unrelated Double Umbilical Cord Blood Units TransplantationNo drug interventionstreatment2 / 3unknown_status
NCT03026842
Decitabine Versus Conventional Chemotherapy for Maintenance Therapy of Acute Myeloid Leukemia With t(8;21)prevention4active_not_recruiting
NCT05703542
BXCL701 Phase 1 R/R Acute Myeloid Leukemia or Myelodysplastic Syndrometreatment1recruiting
NCT00309842
Myeloablative Umbilical Cord Blood Transplantation in Hematological Diseasestreatment2completed
NCT03507842
A Prospective Randomized Comparison of HDAC vs AD in the Induction Chemothrapy for AML.treatment3unknown_status
NCT00887042
Study of Reduced Toxicity Myeloablative Conditioning Regimen for Cord Blood Transplantation in Pediatric AMLtreatment1 / 2unknown_status
NCT05607199
A First in Human Study of AUR 103 Calcium to Evaluate Safety, Pharmacokinetics and Pharmacodynamicstreatment1recruiting
NCT00723099
Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancertreatment2completed
NCT05919199
PET Tracer Based FDG Signal for Predicting Prognosis in Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT01794299
Safety and Efficacy of Donor T-lymphocytes Depleted ex Vivo of Host Alloreactive T-cells (ATIR) in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical DonorNo drug interventionsprevention2completed
NCT05258799
Dual Growth Factor (rhTPO + G-CSF) and Chemotherapy Combination Regimen for Elderly Patients With Acute Myeloid Leukemia: A Phase II Single-Arm Multicenter StudytreatmentNot Availablerecruiting
NCT01747499
Azacitidine in Patients Undergoing Matched Unrelated Stem Cell Transplantationtreatment1 / 2terminated
NCT04645199
National Longitudinal Cohort of Hematological DiseasesNo drug interventionsNot AvailableNot Availablerecruiting
NCT01305499
A Trial to Evaluate Two Schedules of MS275 in Combination With 5AC in Elderly Patients With Acute Myeloid Leukemia (AML)treatment2active_not_recruiting
NCT03190499
Quality of Life in Children With CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT03246906
Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantationtreatment2active_not_recruiting
NCT06351306
DEC-C and Thioguanine for R/R AMLtreatment2recruiting
NCT03964506
Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) TransplantNo drug interventionstreatment0recruiting
NCT02140606
Phase I Trial to Investigate Cafusertib Hydrochloride in Combination With Low Dose Cytarabine in Chinese Patients With Acute Myeloid Leukaemia (AML)treatment1unknown_status
NCT02040506
A Phase I Study of IGN523 in Subjects With Relapsed or Refractory AMLNo drug interventionstreatment1completed
NCT01477606
Protocol in Acute Myeloid Leukemia With FLT3-ITDtreatment2completed
NCT00125606
Phase 3 Trial for AML Patients in CR2 Comparing 8Gy TBI /Fludarabine to Conditioning With TBI 12Gy/CyclophosphamideNo drug interventionstreatment3terminated
NCT05587049
A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Receiving Oral Venetoclax Tablets in Combination With Subcutaneously (SC) or Intravenously (IV) Injected Azacitidine in ColombiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT05319249
Natural Killer Cell Immunotherapy in Combination With PARP-inhibition in Acute Myeloid Leukemiatreatment1 / 2not_yet_recruiting
NCT00632749
BI 811283 in Combination With Cytarabine in Previously Untreated AML Ineligible for Intensive Treatmenttreatment2completed
NCT04992949
Evaluation of CPX-351 Monotherapy in Acute Myeloid Leukemia Secondary to Myeloproliferative NeoplasmNo drug interventionstreatment2recruiting
NCT03594149
Efficiency of Antibacterial Prophylaxis in Azacitidine Treated Patientsprevention3unknown_status
NCT00171249
An Extension Study to Determine the Safety and Anti-Leukemic Effects of Imatinib Mesylate in Adult Participants With Ph+ Leukemiatreatment2completed
NCT04214249
BLAST MRD AML-1: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Intensive Chemotherapy as Frontline Therapy in Patients With Acute Myeloid Leukemiatreatment2recruiting
NCT04241549
A Study of Cusatuzumab Plus Azacitidine in Japanese Participants With Newly Diagnosed Acute Myeloid Leukemia or High-risk Myelodysplastic Syndrome Who Are Not Candidates for Intensive Treatmenttreatment1completed
NCT03900949
Gentuzumab Ozogamicin and Midostaurin Combination With Standard Cytarabine and Danunorubi Midostaurin as a Novel Approach to Treating Patients With Newly Diagnosed FLT-3 Mutated Acute Myeloid Leukemiatreatment1recruiting
NCT03388749
Study of Liposomal Annamycin for the Treatment of Subjects With Acute Myeloid Leukemia (AML)treatment1 / 2completed
NCT00660036
Phase I/II Study of Mitoxantrone, Etoposide and Gemtuzumab Ozogamicin for Acute Myeloid Leukemiatreatment1terminated
NCT04614636
FT538 in Subjects With Advanced Hematologic Malignanciestreatment1terminated
NCT04067336
First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemiatreatment1 / 2recruiting
NCT00188136
Early Allogeneic Blood Stem Cell Transplantation in High-risk Acute Myeloid Leukemia (AML)treatment2completed
NCT06448013
A Phase I Study Investigating the Combination of the Menin Inhibitor Ziftomenib With Venetoclax and Gemtuzumab in Pediatric Patients With Acute Myeloid Leukemiatreatment1not_yet_recruiting
NCT00988013
Intensity Modulated Total Marrow Irradiation (IM-TMI) for Advanced Hematologic MalignanciesNo drug interventionstreatmentNot Availablecompleted
NCT02236013
A Study of ASP2215 in Combination With Induction and Consolidation Chemotherapy in Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment1completed
NCT02892318
A Study Evaluating the Safety and Pharmacology of Atezolizumab Administered in Combination With Immunomodulatory Agents in Participants With Acute Myeloid Leukemia (AML)treatment1completed
NCT03531918
Gemtuzumab Ozogamicin With G-CSF, Cladribine, Cytarabine & Mitoxantrone for Untreated AML & High-Grade Myeloid Neoplasmtreatment1 / 2completed
NCT01158118
Plerixafor and Sargramostim (GM-CSF) for Mobilization of Allogeneic Sibling Donorstreatment2completed
NCT03310918
A Collaborative Palliative and Leukemia Care Model for Patients With AML and MDS Receiving Non-Intensive TherapyNo drug interventionssupportive_careNot Availablerecruiting
NCT03358719
DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, Decitabine, and Nivolumab in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemiatreatment1completed
NCT03224819
Study of Emerfetamab (AMG 673) in Adults With Relapsed/Refractory Acute Myeloid Leukemia (AML)treatment0terminated
NCT01168219
Busulfan, Fludarabine Phosphate, and Anti-Thymocyte Globulin Followed By Donor Stem Cell Transplant and Azacitidine in Treating Patients With High-Risk Myelodysplastic Syndrome and Older Patients With Acute Myeloid Leukemiatreatment2completed
NCT04835519
Phase I/II Study of Enhanced CD33 CAR T Cells in Subjects With Relapsed or Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1 / 2completed
NCT04827719
BST-236 as a Single Agent in Adults With Relapsed or Refractory AML or HR-MDStreatment2active_not_recruiting
NCT05554419
Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia Following Initial Treatment, The ERASE Study (A MyeloMATCH Treatment Trial)treatment2not_yet_recruiting
NCT03961919
Phase II Trial in Elderly Patients With AML or MDS in Complete Remission Not Eligible for Allogenic Transplanttreatment2completed
NCT04923919
Clinical Study of Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of Myeloid LeukemiaNo drug interventionstreatment0recruiting
NCT04380441
Quality of Life Model for Older Patients With AMLNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04888741
Methods of T Cell Depletion Trial (MoTD)prevention2recruiting
NCT02708641
A Phase II Study of Pembrolizumab as Post-Remission Treatment of Patients ≥ 60 With AMLtreatment2completed
NCT06050941
Reduced Intensive Idarubicin and Cytarabine Plus Venetoclax as First-line Treatment for Adults AML and MDStreatment2not_yet_recruiting
NCT00476541
NOPHO-AML 2004 Study for Children With Acute Myeloid Leukemiatreatment3completed
NCT06297941
Study of REM-422 in Patients With AML or Higher Risk MDStreatment1recruiting
NCT03582241
NGS in AML RelapseNo drug interventionsNot AvailableNot Availableunknown_status
NCT03435341
Survival in Patients Older Than 60 Years With Newly Diagnosed AML in SpainNo drug interventionsNot AvailableNot Availablecompleted
NCT03257241
A PALG Prospective Multicenter Clinical Trial to Compare the Efficacy of Two Standard Induction Therapies (DA-90 vs DAC) and Two Standard Salvage Regimens (FLAG-IDA vs CLAG-M) in AML Patients ≤ 60 Years Oldtreatment3unknown_status
NCT03701217
Eltrombopag Used in Thrombocytopenia After Comsolidation Therapy in AMLtreatment2 / 3unknown_status
NCT03178617
High-Intensity Parent Intervention Program in Improving Learning and School Functioning in Latino Children With Acute Leukemia or Lymphoblastic LymphomaNo drug interventionssupportive_careNot Availableactive_not_recruiting
NCT01200017
Expanded Access Protocol (EAP) Using the CliniMACS® Device for Pediatric Haplocompatible Donor Stem Cell TransplantNo drug interventionsNot AvailableNot Availableno_longer_available
NCT02171117
Safety and Efficacy Study of Microtransplantation to Treat Elderly Acute Myeloid LeukemiaNo drug interventionstreatment3unknown_status
NCT06419634
Study of BMS-986497 (ORM-6151) in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic SyndromeNo drug interventionstreatment1recruiting
NCT05503134
Safety and Efficacy of Expanded, Universal Donor Natural Killer Cells for Relapsed/Refractory AMLtreatment1 / 2recruiting
NCT01358734
A Study Being Conducted at Multiple Locations to Compare Safety and Efficacy of Three Different Regimens; (1) High-Dose Lenalidomide; (2) Lenalidomide + Azacitidine; or (3) Azacitidine in Subjects ≥ 65 Years With Newly-Diagnosed Acute Myeloid Leukemiatreatment2completed
NCT03207334
iCare4: Genomic Signatures With Midostaurin in Acute Myeloid Leukemia (UF-HEM-004)treatment2withdrawn
NCT01843634
Ph I Safety and Efficacy of ODSH in Patients Receiving Induction or Consolidation Therapy for Acute Myeloid LeukemiaNo drug interventionstreatment0completed
NCT00491634
Treosulfan-based Conditioning for Transplantation in AML/MDStreatment2completed
NCT03150134
Early Tapering of Immunosuppressive Agents to Immunomodulation to Improve Survival of AML Patientstreatment4unknown_status
NCT01361334
Pilot Clinical Trial of Pazopanib in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or at Initial Diagnosis When no Intensive Treatment is Possibletreatment2completed
NCT04824924
A Phase 2 Study of Venetoclax in Combination With Low-dose HHT, G-CSF, and AZA as First-line Treatment for Newly Diagnosed Elderly AML Patients Unfit for Intensive Chemotherapytreatment2unknown_status
NCT05558124
CPX-351 in Combination With Gemtuzumab Ozogamicin in Newly Diagnosed AMLtreatment1recruiting
NCT02698124
Decitabine for Chemotherapy Unfit Korean AML Patients in Real PracticeNot AvailableNot Availableunknown_status
NCT03573024
Venetoclax and Azacitidine for Non-Elderly Adult Patients With Acute Myeloid Leukemiatreatment2recruiting
NCT04015024
A Clinical Study of SKLB1028 Capsule in the Treatment of Recurrence/Refractory AML PatientsNo drug interventionstreatment2unknown_status
NCT03926624
Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvagetreatment3recruiting
NCT00965224
Efficacy of Dendritic Cell Therapy for Myeloid Leukemia and MyelomaNo drug interventionstreatment2unknown_status
NCT01110824
Prevention of Left Ventricular Dysfunction During Chemotherapyprevention3completed
NCT01690624
BI 836858 Dose Escalation in Patients With Refractory or Relapsed Acute Myeloid Leukemia and in Patients in Complete Remission With High Risk to Relapsetreatment1completed
NCT03050216
QUILT-3.033: Haplo NK With SQ ALT-803 for Adults With Relapsed or Refractory AMLtreatment2completed
NCT05326516
A Study of Revumenib in Combination With Chemotherapy in Participants With R/R Acute Leukemiatreatment1completed
NCT00606216
Structural Imaging and Cognitive Functions in Adult Stem Cell Transplant Recipients Treated With Chemotherapy Alone or in Combination With RadiotherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT04659616
Pemigatinib After Chemotherapy for the Treatment of Newly Diagnosed Acute Myeloid Leukemiatreatment1recruiting
NCT03318016
Arsenic Trioxide With Cyclophosphamide in Patients With Relapsed/Refractory Acute Myeloid Leukemiatreatment1terminated
NCT00342316
Reduced Intensity Conditioning Transplantation Versus Standard of Care in Acute Myeloid LeukemiaNo drug interventionstreatmentNot Availablecompleted
NCT04623216
Sabatolimab as a Treatment for Patients With Acute Myeloid Leukemia and Presence of Measurable Residual Disease After Allogeneic Stem Cell Transplantation.treatment1 / 2active_not_recruiting
NCT01347996
Maintenance Therapy With Ceplene® (Histamine) and IL-2 on Immune Response and MRD in Acute Myeloid Leukemiatreatment4completed
NCT05589896
A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic MalignanciesNo drug interventionstreatment1 / 2recruiting
NCT04006496
AML Expressive WritingNo drug interventionssupportive_careNot Availableterminated
NCT03970096
Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)treatment2recruiting
NCT02182596
DNR and AraC Combined to Fractionated Mylotarg® in Patients With First Relapse of AMLtreatment1 / 2completed
NCT01303796
A Study of Oral Sapacitabine in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment3completed
NCT01520558
CNDO-109-AANK for AML in First Complete Remission (CR1)treatment1 / 2unknown_status
NCT02014558
Dose Escalation Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics of ASP2215 in Patients With Relapsed or Refractory Acute Myeloid Leukemiatreatment1 / 2completed
NCT03987958
A Study to Describe the Safety and Effectiveness of Venetoclax in Acute Myeloid Leukemia (AML) Patients (REVIVE Study)No drug interventionsNot AvailableNot Availablesuspended
NCT00241358
Study Evaluating AMD3100 for Transplantation of Sibling Donor Stem Cells in Patients With Hematological Malignanciestreatment1 / 2completed
NCT05458258
Studying Malnutrition And Sarcopenia In Older Adults With Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT02942758
Low-dose AZA, Pioglitazone, ATRA Versus Standard-dose AZA in Patients >=60 Years With Refractory AMLtreatment2terminated
NCT00428558
Timed-Sequential Induction in CBF-AMLtreatment3completed
NCT03705858
Actinium-225-Lintuzumab in Patients With Acute Myeloid Leukemiatreatment1withdrawn
NCT02890758
Phase I Trial of Universal Donor NK Cell Therapy in Combination With ALT803treatment1completed
NCT05066958
Ex-vivo Primed Memory Donor Lymphocyte Infusion to Boost Anti-viral Immunity After T-cell Depleted HSCTNo drug interventionsprevention1 / 2unknown_status
NCT01770158
Maintenance Therapy With Histamine Dihydrochloride and Interleukin-2 in Adult Acute Myeloid Leukemia (AML) Patients With Measurable Minimal Residual Disease (MRD)- a Non-interventional Study (NIS)No drug interventionsNot AvailableNot Availableterminated
NCT01819558
Phase I/II Study of Immune Therapy After Allograft in Patients With Myeloid HemopathyNo drug interventionstreatment1 / 2completed
NCT03728335
Enasidenib as Maintenance Therapy in Treating Patients With Acute Myeloid Leukemia With IDH2 Mutation After Donor Stem Cell Transplanttreatment1recruiting
NCT05183035
Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)treatment3recruiting
NCT02390635
PET/MRI, 18F-FDG PET/CT and Whole Body MRI in Finding Extramedullary Myeloid Leukemia in Patients With Newly Diagnosed Acute Myeloid Leukemiadiagnostic1recruiting
NCT02319135
Azacytidine (Vidaza®) Versus Fludarabine and Cytarabine (Fluga Scheme) in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment3completed
NCT01757535
Efficacy of Oral Azacitidine Plus Best Supportive Care as Maintenance Therapy in Subjects With Acute Myeloid Leukemia (AML) in Complete Remissiontreatment3completed
NCT05595135
Mobile Intervention to Improve Adherence of Oral Anti-cancer Medications Among Acute Myeloid Leukemia Patients, the txt4AML StudyNo drug interventionshealth_services_researchNot Availablewithdrawn
NCT05166135
Latin American Real-world Study in Acute LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT04460235
Immunogenicity of an Anti-pneumococcal Combined Vaccination in Acute Leukemia or Lymphomatreatment4recruiting
NCT06180863
Oral Azacitidine (CC-486) Epigenetic Priming and Maintenance for Adult Acute Myeloid Leukemia (AML) Patientstreatment2withdrawn
NCT06456463
A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapytreatment2not_yet_recruiting
NCT02275663
Azacytidine Plus FLAG for Relapsed or Refractory AMLtreatment2unknown_status
NCT04460963
Role of Adrenomedullin in Leukemic Endosteal/Vascular NichesNo drug interventionsbasic_scienceNot Availablerecruiting
NCT02270463
SL-401 as Consolidation Therapy in Patients With Adverse Risk Acute Myeloid Leukemia in First Complete Remissiontreatment1 / 2terminated
NCT02573363
Selinexor With Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemiatreatment1completed
NCT04219163
Chimeric Antigen Receptor T-cells for The Treatment of AML Expressing CLL-1 AntigenNo drug interventionstreatment1recruiting
NCT01039363
Vorinostat Combined With Gemtuzumab Ozogamicin, Idarubicin and Cytarabine in Acute Myeloid Leukemiatreatment2unknown_status
NCT03813186
Effect of Food on Blood Levels of ASTX727basic_science1completed
NCT01133886
Use of Decitabine in Myelodysplastic Syndrome (MDS) Following Azacitidine (AZA) Failuretreatment2unknown_status
NCT02923986
Clinical Trial of BP1001 (Liposomal Grb2 Antisense Oligonucleotide) in Combination With Dasatinib in Patients With Ph + CML Who Have Failed TKI, Ph+ AML, Ph+ MDStreatment1 / 2withdrawn
NCT03267186
Ibrutinib in Preventing Acute Leukemia in Patients After Reduced-Intensity Conditioning and Stem Cell Transplanttreatment2completed
NCT03467386
Total Marrow and Lymphoid Irradiation Before Donor Transplant and Cyclophosphamide in Treating Patients With Acute Myeloid Leukemiatreatment1recruiting
NCT01332786
Safety Study Evaluating Intravenous Infusions of Tigecycline to Treat Acute Myeloid Leukemiatreatment1completed
NCT03333486
Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancertreatment2active_not_recruiting
NCT05215639
A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy in Switzerland and Austria Receiving Oral Venetoclax TabletsNo drug interventionsNot AvailableNot Availablecompleted
NCT00860639
Efficacy of Gemtuzumab Ozogamycin for Patients Presenting an Acute Myeloid Leukemia (AML) With Intermediate Risktreatment3completed
NCT03019939
Isavuconazole in Preventing Invasive Fungal Infections in Adult Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome and Neutropeniaprevention2completed
NCT05744739
Tomivosertib in Relapsed or Refractory Acute Myeloid Leukemia (AML)treatment1active_not_recruiting
NCT06463639
FLT3 Clonal Evolution in Patients With Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT05149339
Vitamin D Effect on A Disintegrin-like And Metalloprotease Thrombospondin1 Motif 13& Interleukin 6 in Leukemiatreatment1 / 2completed
NCT01034839
High-dose Cytarabine and Survival in AMLNo drug interventionsNot AvailableNot Availablecompleted
NCT00510939
Study to Assess the Safety, Tolerability, and Efficacy of Tipifarnib Plus Bortezomib in the Treatment of Acute Myeloid Leukemiatreatment2unknown_status
NCT03303339
Onvansertib in Combination With Either Low-dose Cytarabine or Decitabine in Adult Patients With Acute Myeloid Leukemia (AML)treatment1 / 2completed
NCT00413439
Safety, Efficacy and Pharmacokinetics of an Antifungal in Patients Undergoing Chemotherapyprevention2 / 3completed
NCT00514722
Pilot Study of Umbilical Cord Blood Transplantation in Adult Patient With Advanced Hematopoietic MalignanciesNo drug interventionstreatmentNot Availableterminated
NCT00878722
Trial of PXD101 (Belinostat) in Combination With Idarubicin to Treat AML Not Suitable for Standard Intensive Therapytreatment1 / 2completed
NCT00761722
Safety & Pharmacokinetics Study Of Azacitidine (SC And Oral) In Subjects With MDS, CMML, AML, Lymphoma And Multiple Myelomatreatment1completed
NCT05400122
Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancertreatment1recruiting
NCT00636922
Everolimus (RAD001) in Elderly Patients With Acute Myeloid Leukemiatreatment1unknown_status
NCT02759822
Haploidentical Hematopoietic Stem Cell Transplantation for Acute LeukemiasNo drug interventionsNot AvailableNot Availableunknown_status
NCT01489722
Safety, Tolerability, Pharmacokinetics and Efficacy of AZD1208 in Acute Myelogenous Leukemia (AML) PatientsNo drug interventionstreatment1terminated
NCT02677922
A Study to Assess the Safety and Efficacy of Two Combinations of Isocitrate Dehydrogenase (IDH) Mutant Targeted Therapies Plus Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) Harboring IDH Mutations Who Are Not Candidates to Receive Intensive Induction Chemotherapytreatment1 / 2active_not_recruiting
NCT01176422
Telomere and TelomeraseNo drug interventionsNot AvailableNot Availablewithdrawn
NCT04215822
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01947322
Haploidentical NK-cell Infusion in Acute Myeloid Leukemiatreatment1 / 2completed
NCT02238522
Phase 1 Study Evaluating ZEN003365 in Relapsed/Refractory Lymphoproliferative Malignancies or Relapsed/Refractory AMLNo drug interventionstreatment1withdrawn
NCT00363025
A Randomized Study of Post-Remission Therapy in Elderly Patients With Acute Myelogenous Leukemia.treatment3terminated
NCT00806325
Clinical Factors Associated With the Development of Severe Sepsis in Patients Being Treated for Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT04209725
A Study of CPX-351 (Vyxeos™) With Quizartinib for the Treatment of FLT3-ITD Mutation-Positive Acute Myeloid Leukemiatreatment2terminated
NCT05053425
Bcl-2 Inhibitors Combined With Azacytidine and Chemotherapy in Elderly Patients With Previously Untreated AMLtreatmentNot Availableunknown_status
NCT01455025
Study in Plerixafor and Granulocyte-colony Stimulating Factor Patients With Relapse Acute Myeloid Leukemiatreatment1terminated
NCT06162325
Venetoclax in Combination With Standard Induction and Consolidation Chemotherapy in Newly Diagnosed Young AML PatientsNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT01793025
Mismatched Donor Cells to Treat Acute Myeloid LeukemiaNo drug interventionstreatment1unknown_status
NCT06301425
MRD Response-adapted Allo-HSCT for Adverse-risk AMLNo drug interventionstreatmentNot Availablerecruiting
NCT06571825
RIC Allo-HSCT vs. Venetoclax-Based Consolidation in Elderly AML Patients After First CRtreatment4recruiting
NCT03038230
MCLA-117 in Acute Myelogenous LeukemiaNo drug interventionstreatment1unknown_status
NCT04629430
Effects of Prebiotics on Gut Microbiome in Patients Undergoing HSCTNo drug interventionstreatmentNot Availablecompleted
NCT02900430
Invasives Aspergillosis in Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT05153330
Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NPM1 Mutations), DLBCL, MM, and CLL/SLLNo drug interventionstreatment1recruiting
NCT06073730
Comparison of the Efficacy and Safety of Venetoclax in Combination With 3 Days Decitabine (DEC3-VEN) vs. Venetoclax in Combination With Azacitidine (VIALE-A) in the Treatment of Elderly Patients or Unfit, New-diagnosis Acute Myeloid Leukemia PatientsNo drug interventionstreatment3not_yet_recruiting
NCT03434730
Tocilizumab for the Prevention of Graft Versus Host Disease After Cord Blood Transplantationtreatment2active_not_recruiting
NCT04511130
Efficacy of MT-401 in Patients With AML Following Stem Cell Transplanttreatment2active_not_recruiting
NCT04942730
Benadamustine, Fludarabine and Busulfan Conditioning in Recipients of Haploidentical Stem Cell Transplantation (FluBuBe)treatment2completed
NCT03420430
Expanded Access to Provide GL-ONC1 for the Treatment of Advanced Cancers With No Standard of CareNot AvailableNot Availabletemporarily_not_available
NCT03280030
A Study of Midostaurin Efficacy and Safety in Newly Diagnosed Patients With FLT3-mutated AMLtreatment2completed
NCT03338348
Study of Vosaroxin With Azacitidine in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome With Excess Blasts-2treatment2completed
NCT03844048
An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trialtreatment3active_not_recruiting
NCT02381548
Phase I Trial of AZD1775 and Belinostat in Treating Patients With Relapsed or Refractory Myeloid Malignancies or Untreated Acute Myeloid Leukemiatreatment1terminated
NCT02979548
Study to Evaluate the Effect of Aprepitant in Children and Adolescents Receiving AML Remission Induction Chemotherapyprevention3unknown_status
NCT03173248
Study of AG-120 (Ivosidenib) vs. Placebo in Combination With Azacitidine in Participants With Previously Untreated Acute Myeloid Leukemia With an IDH1 Mutationtreatment3active_not_recruiting
NCT00129948
Study for Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)treatment2terminated
NCT05431257
Azacitidine in Combination With Low Dose Intensity Venetoclax in Patients With AML Incl. Explorative AML Profilingtreatment2recruiting
NCT03164057
A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment2active_not_recruiting
NCT04943757
Post-transplantation Benadamustine and Cyclophosphamide in Patients With Refractory Myeloid Malignanciestreatment2recruiting
NCT01615757
Safety and Efficacy Study of Ara-c at 18 gm/m2 Versus 12 gm/m2 for 3 Cycles Each in AML Consolidationtreatment3unknown_status
NCT03862157
Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment1 / 2active_not_recruiting
NCT03723057
Expanded Access for AG-221Not AvailableNot Availableno_longer_available
NCT01211457
Study of Sapacitabine in Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS)treatment1 / 2unknown_status
NCT06146257
A Study of GLB-001 in Patients With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher Risk Myelodysplastic SyndromesNo drug interventionstreatment1recruiting
NCT01420926
Decitabine With or Without Bortezomib in Treating Older Patients With Acute Myeloid Leukemiatreatment2completed
NCT00145626
HLA-Nonidentical Stem Cell and Natural Killer Cell Transplantation for Children Less the Two Years of Age With Hematologic Malignanciestreatment2completed
NCT04628026
Phase III Study of Induction and Consolidation Chemotherapy With Venetoclax in Patients With Newly Diagnosed AML or MDS-EB-2treatment3recruiting
NCT04052126
An Individualized Physical Activity Program in Patients Over 65 Years With Hematologic MalignanciesNo drug interventionssupportive_careNot Availablecompleted
NCT01617226
Randomised Study of Azacitidine Versus Azacitidine With Vorinostat in Patients With AML or High Risk MDStreatment2completed
NCT00541866
Safety and Tolerability Study of Voreloxin and Cytarabine Combination in Acute Myeloid Leukemia in Humanstreatment1 / 2completed
NCT04822766
A Study Comparing Allogeneic Hematopoietic Cell Transplantation Versus Best Available Standard of Care Therapy in Elderly Patients With Acute Myeloid LeukemiaNo drug interventionstreatmentNot Availablerecruiting
NCT02298166
Study of Crenolanib in Combination With Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia and Activating FLT3 Mutationstreatment3terminated
NCT03066466
Randomized Study: Standard of Care With or Without Atorvastatin for Prevention of GVHD for Matched Unrelated Donor BMTprevention3withdrawn
NCT00701766
BI 2536 Infusional Treatment in Patients Over 60 Years of Age With Refractory or Relapsed Acute Myeloid Leukaemiatreatment2completed
NCT03760666
A Study of Brequinar in Subjects With Relapsed/Refractory Acute Myeloid Leukemiatreatment1 / 2terminated
NCT00727766
Oral Clofarabine for Acute Myeloid Leukemiatreatment1completed
NCT03080766
The Use of Decitabine as Induction Therapy for Acute Myeloid Leukemia With Complex and/or Monosomal Karyotypetreatment2unknown_status
NCT05219266
Managed Access Programs for PKC412, MidostaurinNot AvailableNot Availableno_longer_available
NCT04678466
Flotetuzumab Expanded Access ProgramNot AvailableNot Availableno_longer_available
NCT01433965
Study of Lenalidomide in Patients With Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrometreatment1completed
NCT02498665
A Study of DSP-7888 Dosing Emulsion in Adult Patients With Advanced Malignanciestreatment1completed
NCT02462265
Oshadi D & Oshadi R Combined With Salvage Chemotherapy for Relapsed Acute Myeloid Leukemia or Lymphoid Leukemia Patientstreatment2suspended
NCT02665065
Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid LeukemiaNo drug interventionstreatment3active_not_recruiting
NCT05154474
Assessment of Sarcopenia at Diagnosis for Patients With Previously Untreated Metastatic Cancer or Hematologic MalignancyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02719574
Open-label Study of FT-2102 With or Without Azacitidine or Cytarabine in Patients With AML or MDS With an IDH1 Mutationtreatment1 / 2completed
NCT04282174
CD34+ Enriched Transplants From HLA-Compatible Patients With Hematologic Malignanciestreatment2withdrawn
NCT01912274
Safety and Efficacy Study of Pracinostat With Azacitadine in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)treatment2completed
NCT01067274
ALFA-0703 Study in Older Patients With Acute Myeloblastic Leukemia (AML)treatment3withdrawn
NCT02527174
A Study of Volasertib Plus Induction Chemotherapy for Acute Myeloid Leukemiatreatment1withdrawn
NCT01478074
ALT-801-activated Natural Killer Cells After FLAG Induction for Acute Myeloid Leukemiatreatment1withdrawn
NCT06206174
TGRX-814 Chinese Phase I/II in Patients With Hematological MalignanciesNo drug interventionstreatment1 / 2recruiting
NCT03850574
Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemiatreatment1 / 2recruiting
NCT03314974
Myeloablative Allo HSCT With Related or Unrelated Donor for Heme DisordersNo drug interventionstreatment2recruiting
NCT04788420
Influence of Co-existing Mutations on Sorafenib Maintenance Therapy After Allo-HSCT for Patients With FLT3-ITD AMLNot AvailableNot Availablecompleted
NCT00703820
Clofarabine Plus Cytarabine Versus Conventional Induction Therapy And A Study Of NK Cell Transplantation In Newly Diagnosed Acute Myeloid Leukemiatreatment3completed
NCT02770820
Laboratory-Treated (Central Memory/Naive) CD8+ T Cells in Treating Patients With Newly Diagnosed or Relapsed Acute Myeloid Leukemiatreatment1 / 2terminated
NCT01249820
Pharmacokinetics of Anidulafungin (Ecalta ®) Intravenous Given to Patients at High Risk for Developing Invasive Fungal Diseaseother2completed
NCT00728520
Trial With Azacitidine in Newly Diagnosed Acute Myelogenous Leukemia (AML) Veterans Administration (VA) Elderly Patients Not Eligible for Standard Induction Therapytreatment2unknown_status
NCT00146120
Risk-Adapted Therapy of Acute Myeloid Leukemia of Adults (18-60 Years) According to the Cytogenetic Resulttreatment3completed
NCT01301820
Elderly Patients With Acute Myeloid Leukemia (AML), Maintenance Phase After Complete Remission (CR)treatment2completed
NCT04133220
Endothelial Activation Hemostasis Disturbances and Severe Bleeding Events in Hyperleukocytic Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT06572982
Extension Study, Pilot, Compassionate Use of Azacitidine 300 mg Film Coated Tablets for Acute Myeloid Leukaemia (AML) PatientstreatmentNot Availablenot_yet_recruiting
NCT02303782
A Study Assessing tOTX015 in Combination With Azacitidine (AZA) or AZA Single Agent in Patients With Newly-diagnosed Acute Myeloid Leukemia (AML) Not Candidate for Standard Intensive Induction Therapy (SIIT)treatment1 / 2withdrawn
NCT01045382
MSC and HSC Coinfusion in Mismatched MinitransplantsNo drug interventionstreatment2terminated
NCT00153582
WT1 Peptide Vaccination in Acute Myeloid Leukemia (AML)No drug interventionstreatment2unknown_status
NCT06357182
Iadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid Leukemiatreatment1recruiting
NCT03556982
CART-123 FOR Relapsed/Refractory Acute Myelocytic Leukemia(AML)No drug interventionstreatment1 / 2unknown_status
NCT06511882
Discontinuation of Hypomethylating Agent and Venetoclax in Patients With AML MRDtreatment2recruiting
NCT03867682
Venetoclax and Lintuzumab-Ac225 in AML Patientstreatment1 / 2recruiting
NCT01713582
A Dose-finding Study of the Bromodomain (Brd) Inhibitor OTX015/ Birabresib (MK-8628) in Hematologic Malignancies (MK-8628-001)treatment1completed
NCT06337331
Adding Venetoclax to the High-dose Chemotherapy Regimen Prior to Mismatche Allogeneic Stem Cell Transplanttreatment2withdrawn
NCT05042531
Clinical Research for Azacitidine Combined With Low-dose Dasatinib in Maintenance Therapy of Acute Myeloid LeukemiatreatmentNot Availableunknown_status
NCT00925873
GOELAMS SA4 Study: the Role of Fludarabine in the Treatment of Acute Myeloid Leukemia in the Elderlytreatment3completed
NCT02003573
Volasertib + Decitabine in Patients With Acute Myeloid Leukemia (AML)treatment1terminated
NCT00373373
Efficacy of Sorafenib Added to Standard Primary Therapy in Elderly Patients With Newly Diagnosed AMLtreatment2completed
NCT03828773
PTX3-targeted Antifungal ProphylaxispreventionNot Availablerecruiting
NCT02264873
Phase I, Dose Escalation Study of Decitabinetreatment1completed
NCT00322673
Study of XL999 in Patients With Acute Myeloid Leukemia (AML)treatment2terminated
NCT06498973
Tagraxofusp and Azacitidine for Maintenance Treatment in Patients With CD123 Positive AML and MDS Following Donor Hematopoietic Cell Transplanttreatment1not_yet_recruiting
NCT01010373
Safety and Efficacy Study of AS101 to Treat Elderly Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Patientstreatment2suspended
NCT06513273
Observational Study on the Outcome of AML Patients Treated With New Drugs in Real-life (BoxTrial)No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02842827
A Study of Bomedemstat (IMG-7289/MK-3543) With and Without ATRA, in Participants With Advanced Myeloid Malignancies (IMG-7289-CTP-101/MK-3543-001)treatment1 / 2completed
NCT06256627
The Maintenance Treatment of "ITIVA" in AML PatientsotherNot Availablerecruiting
NCT03154827
Safety, Tolerability and Efficacy of the BL-8040 and Atezolizumab for Maintenance Treatment in Subjects With Acute Myeloid Leukemia (AML)treatment1 / 2terminated
NCT00864227
Evaluating the Safety and Effectiveness of an Umbilical Cord Blood Stem Cell Transplant (BMT CTN 0604)No drug interventionstreatment2completed
NCT05377827
Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignanciestreatment1recruiting
NCT02742727
CAR-pNK Cell Immunotherapy in CD7 Positive Leukemia and Lymphomatreatment1 / 2unknown_status
NCT00667927
Autologous Bone Marrow Transplant for Children With Acute Myelogenous Leukemia (AML) in First Complete Remissiontreatment1completed
NCT03885076
Gamma Delta T Cells in AMLNo drug interventionsNot AvailableNot Availableunknown_status
NCT04745676
A Telehealth Advance Care Planning Intervention for Older Patients With Acute Myeloid Leukemia and Myelodysplastic SyndromeNo drug interventionssupportive_careNot Availableactive_not_recruiting
NCT00789776
Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation, and Donor Bone Marrow Transplant Followed by Donor Natural Killer Cell Therapy, Mycophenolate Mofetil, and Tacrolimus in Treating Patients With Hematologic Cancertreatment1 / 2completed
NCT01344876
Phase I Study of OPB-51602 in Patients With Hematologic MalignanciesNo drug interventionstreatment1completed
NCT04914676
Accelerated Dose Schedule of Cytarabine Consolidation Therapy for Older Patients With Acute Myeloid Leukemia (AML) in Complete Remissiontreatment2active_not_recruiting
NCT05428176
A High Intensity Electronic Health Intervention for the Reduction of Learning Disparities in Childhood Cancer SurvivorsNo drug interventionssupportive_careNot Availablerecruiting
NCT02605460
Chemo Sensitization Before Hematopoietic Stem Cell Transplantation in Patients With Acute Leukemia in Complete Remissiontreatment2unknown_status
NCT03563560
A Study of DSP-2033 (Alvocidib) in Patients With Acute Myeloid Leukemiatreatment1completed
NCT00235560
Rapamycin in Combination With Low-dose Aracytin in Elderly Acute Myeloid Leukemia Patientstreatment2completed
NCT06379360
Maintenance Therapy of Hypomethylating Agent (HMA) in Favorable Risk Acute Myeloid Leukemia (AML) Patientstreatment2recruiting
NCT03609060
Dexamethasone Added to Intensive Chemotherapy in Older Patients With Acute Myeloid Leukemia (AML)treatment2active_not_recruiting
NCT01534260
Phase I/II Study of Combination of Sorafenib, Vorinostat, and Bortezomib for the Treatment of Acute Myeloid Leukemia With Complex- or Poor-risk (Monosomy 5/7) Cytogenetics or FLT3-ITD Positive Genotypetreatment1 / 2completed
NCT05599360
Vyxeos for Induction of Low- or Intermediate-risk.treatment2recruiting
NCT03516760
Dose-escalating Phase I Trial With GEM333 in Patients With Acute Myeloid LeukemiaNo drug interventionstreatment1terminated
NCT02614560
A Study of Vadastuximab Talirine Given Prior to or After Allogeneic Hematopoietic Stem Cell Transplant in AML Patientstreatment1 / 2terminated
NCT04968860
Oral Health Condition and Quality of Life in Children With LeukemiaNo drug interventionsNot AvailableNot Availableterminated
NCT03537560
Detection of IDH2 Mutations and Monitoring Molecular Residual Disease in Patients With AMLNo drug interventionsNot AvailableNot Availablecompleted
NCT03471260
Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignanciestreatment1 / 2recruiting
NCT05455294
Combination Navitoclax, Venetoclax and Decitabine for Advanced Myeloid Neoplasmstreatment1active_not_recruiting
NCT04858594
Study of Periodontitis and Blood Stream Infection in AML Patients Receiving ChemotherapyNo drug interventionsNot AvailableNot Availableterminated
NCT00822094
Trial of CPX-351 in Adult Patients With First Relapse Acute Myeloid Leukemia (AML)No drug interventionstreatment2completed
NCT05317494
A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy Receiving Oral Venetoclax Tablets in GreeceNo drug interventionsNot AvailableNot Availablerecruiting
NCT00460694
Allogeneic Cytokine-induced Killer Immunotherapy for Relapse After Allogeneic Marrow Transplant for Haematological MalignanciesNo drug interventionstreatment1 / 2completed
NCT04662294
CD 70 CAR T for Patients With CD70 Positive Malignant Hematologic DiseasesNo drug interventionstreatment0recruiting
NCT05249894
Evaluation of Infective Risk, Efficacy of Bacterial Prophylaxis and Validation of Sepsis Scores NEWS (National Early Warning Score) and qSOFA (Quick Sequential Organ Failure Assessment) in Patient With Acute Myeloid Leukemia Treated With Intensive ChemotherapyNo drug interventionsNot AvailableNot Availableunknown_status
NCT03466294
Azacitidine and Venetoclax as Induction Therapy With Venetoclax Maintenance in the Elderly With AMLtreatment2active_not_recruiting
NCT01066494
A Pharmacokinetic and Efficacy Study of Amonafide L-malate (AS1413) in Combination With Cytarabine in Patients With Acute Myeloid Leukemia (AML)treatment2unknown_status
NCT04435691
Magrolimab, Azacitidine, and Venetoclax for the Treatment of Acute Myeloid Leukemiatreatment1 / 2active_not_recruiting
NCT00969891
Study of Dosage Individualisation for the Treatment of Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT05622591
ELU001 in Pediatric Subjects Who Have Relapsed and/or Refractory CBFA2T3-GLIS2-positive AMLNo drug interventionstreatment1withdrawn
NCT00422591
Standard Idarubicin and Cytarabine for the Treatment of Acute Myeloid Leukemia (AML)treatment2completed
NCT03187691
Safety and PK of Oral Encochleated Amphotericin B (CAMB/MAT2203) for Antifungal Prophylaxis in Patients Undergoing Induction Chemotherapy for Acute Myelogenous and Lymphoblastic Leukaemiaprevention2withdrawn
NCT06195891
Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrometreatment1recruiting
NCT02472691
Azacitidine, Lenalidomide and DLI as Salvage Therapy for MDS, CMML and sAML Relapsing After Allo-HSCTtreatment2completed
NCT05055791
A Study to Evaluate the Safety and Tolerance of SYHX1903 in Patients With Relapsed/Refractory Hematologic MalignanciesNo drug interventionstreatment1 / 2not_yet_recruiting
NCT02867891
Sorafenib In Relapse of FMS-like Tyrosine Kinase 3 (FLT3)-Internal Tandem Duplication (ITD) AML TrialNo drug interventionsNot AvailableNot Availablecompleted
NCT04293562
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutationstreatment3active_not_recruiting
NCT06299462
PTCy and ATG for MSD and MUD Transplantsprevention1 / 2recruiting
NCT05424562
A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy Receiving Oral Venetoclax Tablets in CanadaNo drug interventionsNot AvailableNot Availablerecruiting
NCT06484062
Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 and ASTX727 With Venetoclax to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromestreatment1not_yet_recruiting
NCT01572662
Allogeneic Transplantation Using Timed Sequential Busulfan and Fludarabine Conditioningtreatment2completed
NCT02937662
Efficacy of Idarubicin, Cytarabine and Cyclophosphamide (IAC) Regimen in Relapsed/Refractory AMLtreatment2unknown_status
NCT00172562
Bone Marrow Angiogenesis in Acute Myeloid Leukemia - Evaluated by Dynamic Contrast Enhanced Magnetic Resonance (MR) ImageNo drug interventionsNot AvailableNot Availableunknown_status
NCT05949762
Safety and Efficacy of Venetoclax in Combination With Azacitidine and HA Regimen in the Treatment of AML in the ElderlyNo drug interventionstreatment1 / 2recruiting
NCT05364762
Adding Itacitinib to Cyclophosphamide and Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Hematopoietic Stem Cell Transplantsprevention2recruiting
NCT06369662
CD155 Expression in Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02944162
CAR-pNK Cell Immunotherapy for Relapsed/Refractory CD33+ AMLtreatment1 / 2unknown_status
NCT03665480
The Effect of G-CSF on MRD After Induction Therapy in Newly Diagnosed AMLsupportive_care2 / 3unknown_status
NCT03356080
DLAAG in the Treatment of Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome With Blast Excesstreatment2unknown_status
NCT01541280
VIDAZA-DLI Pre-emptive Azacitidine and Donor Lymphocyte Infusions Following Allogeneic Hematopoietic Stem Cell Transplantation for High Risk Acute Myeloid Leukemia and Myelodysplastic Syndrometreatment2completed
NCT04013880
ASTX727 and FT-2102 in Treating IDH1-Mutated Recurrent/Refractory Myelodysplastic Syndrome or Acute Myeloid Leukemiatreatment1 / 2withdrawn
NCT00529880
Fludarabine and Cytarabine as Continuous Infusion Plus G-CSF Priming for Elderly Patients With Resistant AMLtreatment2unknown_status
NCT05939180
VA vs DA for Newly Diagnosed Hig-risk AMLtreatment2 / 3recruiting
NCT04067180
Randomized Clinical Study Assessing Haplo vs. URD in AMLNo drug interventionstreatmentNot Availableterminated
NCT03833180
A Study of Zilovertamab Vedotin (MK-2140) (VLS-101) in Participants With Hematologic Malignancies (MK-2140-001)treatment1completed
NCT00957580
Trial of Pimasertib in Hematological Malignanciestreatment2terminated
NCT03589729
Dexrazoxane Hydrochloride in Preventing Heart-Related Side Effects of Chemotherapy in Participants With Blood Cancerssupportive_care2recruiting
NCT02493829
B7.1/IL-2 Leukaemia Cell Vaccine for Non-Transplant AML RFUSIN2-AML2 (NTX)No drug interventionstreatment1unknown_status
NCT06295029
Personalized Medication Software for BCL-2 Inhibitor in AML Patients Using Machine Learning and GenomicsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04150029
A Study of MBG453 in Combination With Azacitidine and Venetoclax in AML Patients Unfit for Chemotherapytreatment2active_not_recruiting
NCT04166929
Haploidentical Stem Cell Transplant With or Without NK Cell Infusion in AML and MDStreatment2terminated
NCT01599429
Study of the Predictive Marker FLT in Patients Suffering From AMLNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00469729
Efficacy and Safety Study of StemEx®, to Treat Subjects With High Risk Hematologic Malignancies, Following Myeloablative Therapytreatment2 / 3completed
NCT02016729
A Phase 1b Study Evaluating AMG 232 Alone and in Combination With Trametinib in Acute Myeloid Leukemiatreatment1completed
NCT06113289
A Phase 1B/2A Trial of Combination of ASTX727 With ASTX029 in Acute Myeloid Leukemiatreatment1 / 2suspended
NCT02936089
Risk Stratification-directed Therapy for AML With t(8;21) /AML1-ETO+No drug interventionstreatmentNot Availablecompleted
NCT04112589
A Clinical Trial to Assess the Efficacy and Safety of the Combination of a Drug Call Quizartinib With Chemotherapy (FLAG-IDA) in Patients With Acute Myeloid Leukemia That Has Not Responded to the First Treatment or That Has Returned After the First Treatmenttreatment1 / 2unknown_status
NCT03042689
Study of Regorafenib in Patients With Advanced Myeloid Malignanciestreatment1completed
NCT00788892
Trial of CPX-351 in Newly Diagnosed Elderly AML Patientstreatment2completed
NCT04310592
Natural Killer Cell (CYNK-001) Infusions in Adults With AMLtreatment1recruiting
NCT05918692
A Phase 1, Study of BMF-500 in Adults With Acute LeukemiaNo drug interventionstreatment1recruiting
NCT04931992
Outcome of Patients With CBF and/or NPM1-mutated AML in First Molecular Relapse.No drug interventionsNot AvailableNot Availableunknown_status
NCT06389292
A Pivotal Study of APG-2575 (Lisaftoclax) Combined With Azacytidine in the Treatment of Acute Myeloid Leukemiatreatment3recruiting
NCT00709592
Reduced Intensity Total Body Irradiation + Thymoglobulin Followed by Allogeneic PBSCTtreatment2completed
NCT02809092
Interleukin-21 (IL-21)- Expanded Natural Killer Cells for Induction of Acute Myeloid Leukemiatreatment1 / 2unknown_status
NCT05038644
XmAb18968 (CD3-CD38) in Relapsed or Refractory Acute Leukemia and T Cell Lymphoblastic LeukemiaNo drug interventionstreatment1active_not_recruiting
NCT04774744
Effect of Digital Health Coaching Program on Self-efficacy and Patient Reported Outcomes of Patients With Newly Diagnosed Acute Myeloid Leukemia or Chronic Lymphocytic LeukemiaNo drug interventionssupportive_careNot Availablecompleted
NCT03860844
Isatuximab in Combination With Chemotherapy in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemiatreatment2terminated
NCT02670044
A Study of Venetoclax in Combination With Cobimetinib and Venetoclax in Combination With Idasanutlin in Patients With Relapsed or Refractory Acute Myeloid Leukemia Who Are Not Eligible for Cytotoxic Therapytreatment1completed
NCT03465540
Safety, Tolerability, Pharmacokinetics and Efficacy of AMG 397 in Subjects With Selected Relapsed or Refractory Hematological Malignanciestreatment1terminated
NCT06399640
Eltanexor and Venetoclax in Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemiatreatment1recruiting
NCT03009240
Pevonedistat and Decitabine in Treating Patients With High Risk Acute Myeloid Leukemiatreatment1active_not_recruiting
NCT01399840
Study of BMN 673, a PARP Inhibitor, in Patients With Advanced Hematological Malignanciestreatment1completed
NCT05986240
Danvatirsen Monotherapy Followed by Combination With Venetoclax in Relapsed/Refractory MDS & AMLtreatment1recruiting
NCT01252667
Clofarabine and Low-Dose Total-Body Irradiation in Treating Patients With Acute Myeloid Leukemia Undergoing Donor Peripheral Blood Stem Cell Transplanttreatment2completed
NCT02781467
A Safety Study of Human Cord Blood Derived, Culture Expanded Natural Killer Cell (PNK-007) Infusion With Subcutaneous Recombinant Human IL-2 (rhIL-2) in Adults With Relapsed and/or Refractory Acute Myeloid Leukemia (AML)treatment1terminated
NCT00809367
Collection and Banking of Leukemia Cells MDS/AMLNo drug interventionsNot AvailableNot Availablecompleted
NCT04797767
Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasmstreatment1suspended
NCT01468467
A Study of AC220 Given After Transplant in Subjects With Acute Myeloid Leukemia (AML)treatment1completed
NCT02494167
Administration of Donor Multi TAA-Specific T Cells for AML or MDS (ADSPAM)No drug interventionstreatment1recruiting
NCT02899767
Transfusion in Adult Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT04669067
TL-895 and KRT-232 Study in Acute Myeloid Leukemiatreatment1 / 2active_not_recruiting
NCT05316701
Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic MalignanciesNo drug interventionstreatment3active_not_recruiting
NCT03734601
Total Body Irradiation +/- Total Lymphoid Irradiation & Anti-Thymocyte Globulin in Non-myeloablative Hematopoietic Cell Transplantationtreatment2completed
NCT05367401
A Study of Sabatolimab and Magrolimab-based Treatment in AML or Higher Risk MDS Participantstreatment1 / 2withdrawn
NCT05000801
Clinical Study of DC-AML Cells in the Treatment of Acute Myeloid LeukemiaNo drug interventionstreatmentNot Availablerecruiting
NCT02848001
A Dose-finding Study of CC-90009 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher-risk Myelodysplastic Syndromestreatment1terminated
NCT01163201
T-Regulatory Cell and CD3 Depleted Double Umbilical Cord Blood Transplantation in Hematologic Malignanciestreatment1 / 2withdrawn
NCT01804101
Liposomal Cytarabine-Daunorubicin CPX-351 in Treating Patients With Untreated Myelodysplastic Syndrome or Acute Myeloid LeukemiatreatmentNot Availablecompleted
NCT03455504
Venetoclax Add in Combination With Fludarabine, Cyratabine and Idarubicine in Induction for Acute Myelid Leukemiatreatment2active_not_recruiting
NCT00850304
Treatment of Non Promyelocytic Acute Myeloid Leukaemia on Elderly Patients by Low Dose Cytosar Plus Arsenic Trioxidetreatment2completed
NCT04842604
Continuation Study of B1371019(NCT03416179) and B1371012(NCT02367456) Evaluating Azacitidine With Or Without Glasdegib In Patients With Previously Untreated AML, MDS or CMMLtreatment3completed
NCT01734304
DC Vaccination for Postremission Therapy in AMLNo drug interventionstreatment1 / 2completed
NCT06197672
Chimeric Antigen Receptor T Cell Redirected to Target CD4 Positive Relapsed Refractory Acute Myeloid Leukemia (AML ) as a Bridge to Allogeneic Stem Cell TransplantNo drug interventionstreatment1recruiting
NCT06279572
Immune Profile of Acute Myeloid Leukemia Patients Receiving Azacitidine Plus Venetoclax Induction ChemotherapyNo drug interventionsNot AvailableNot Availablerecruiting
NCT04259372
Analysis of T Cell Metabolism in Acute Myeloid Leukemia PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT05010772
Decitabine Alone or in Combination With Venetoclax, Gilteritinib, Enasidenib, or Ivosidenib as Maintenance Therapy for the Treatment of Acute Myeloid Leukemia in Remissiontreatment1recruiting
NCT04771572
Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.No drug interventionstreatment1recruiting
NCT02909972
Safety Study of ALRN-6924 in Patients With Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrometreatment1completed
NCT00161668
Study Evaluating Mylotarg (Gemtuzumab Ozogamicin) in Usual CareNot AvailableNot Availablecompleted
NCT01369368
Treatment of Acute Leukemia Relapse After Allotransplantationtreatment1 / 2unknown_status
NCT04940468
High- Fiber/ Low-fat Diet for Prevention of Recurrent Clostridioides Difficile Infection in OncologyNo drug interventionspreventionNot Availablerecruiting
NCT04070768
Study of the Safety and Efficacy of Gemtuzumab Ozogamicin (GO) and Venetoclax in Patients With Relapsed or Refractory CD33+ Acute Myeloid Leukemia:Big Ten Cancer Research Consortium BTCRC-AML17-113treatment1active_not_recruiting
NCT04090268
Precision Exercise in Children With Malignant HemopathiesNo drug interventionstreatmentNot Availablerecruiting
NCT04282668
A Study of TAS1440 With ATRA in Subjects With r/r AMLtreatment1active_not_recruiting
NCT01451268
Phase I/II Study With Oral Panobinostat Maintenance Therapy Following Allogeneic Stem Cell Transplantation in Patients With High Risk Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML)treatment1 / 2unknown_status
NCT02722668
UCB Transplant for Hematological Diseases Using a Non Myeloablative Preptreatment2active_not_recruiting
NCT01343368
Preservation of Ovarian Function After Hematopoietic Cell Transplantsupportive_care2terminated
NCT06326268
Interest of Light Therapy in Hematology - The PHOTO-TREAT StudyNo drug interventionssupportive_careNot Availablerecruiting
NCT06387069
A Study to Evaluate HMPL-306 in Patients With IDH1- and IDH2-mutated Acute Myeloid LeukemiaNo drug interventionstreatment3recruiting
NCT01794169
Azacitidine Compared to Conventional Chemotherapy as Consolidation of Elderly Patients With AMLtreatment2terminated
NCT03902769
Study to Assess Length of Remission With Intensive Chemotherapy in Rapidly Responding AML Patients.No drug interventionstreatmentNot Availableunknown_status
NCT05356169
Intensive Therapy Combined With Venetoclax for Adult Acute Myeloid LeukemiaNo drug interventionstreatment2 / 3not_yet_recruiting
NCT03761069
Study of PTC299 (Emvododstat) in Relapsed/Refractory Acute Leukemiastreatment1terminated
NCT03494569
Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrometreatment1recruiting
NCT03969446
Pembrolizumab and Decitabine With or Without Venetoclax in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome That Is Newly-Diagnosed, Recurrent, or Refractorytreatment1recruiting
NCT01452646
Risk-adapted, MRD-directed Therapy for Young Adults With Newly Diagnosed Acute Myeloid LeukemiaNo drug interventionstreatment2completed
NCT06245746
UCMSC-Exo for Chemotherapy-induced Myelosuppression in Acute Myeloid LeukemiaNo drug interventionstreatment1not_yet_recruiting
NCT00774046
High-dose Cytarabine/Mitoxantrone Followed by Autotransplantation for t-MDS/t-AMLtreatment2completed
NCT04209712
Natural Killer Cells Infusion for Treating Acute Myeloid Leukemia Patients With Minimal Residual DiseaseNo drug interventionstreatment0unknown_status
NCT00932412
The CLARA Study From the Acute Leukemia French Association (ALFA 0702 Trial)No drug interventionstreatment2completed
NCT04896112
A Study of LNK01002 in Patients With Primary or Secondary Myelofibrosis,Polycythemia Vera or Acute Myeloid LeukemiaNo drug interventionstreatment1withdrawn
NCT01169012
PK Study of Oral and IV Clofarabine in High Risk Myelodysplasia+Acute Leukemiasbasic_science1completed
NCT05569512
Uproleselan With Pre-Transplant Conditioning in Hematopoietic Stem Cell Transplantation for AMLtreatment1terminated
NCT06111612
Intensive Conditioning withTHI/Bu/Flu/Ara-C in Allo-HSCT for Myeloid Malignancies With Extramedullary InvolvementNo drug interventionsNot AvailableNot Availablerecruiting
NCT03030612
A Study of ARGX-110 in Combination With Azacytidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) or High Risk Myelodysplatic Syndrome (MDS)treatment1 / 2completed
NCT01231412
Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplanttreatment3completed
NCT03289910
Topotecan Hydrochloride and Carboplatin With or Without Veliparib in Treating Advanced Myeloproliferative Disorders and Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemiatreatment2active_not_recruiting
NCT04641910
Validation Study of a New Cytokine-based Dynamic Stratification Based on FLt3 Ligand Plasma Concentration Kinetic Profile and IL-6 Concentration During Induction of Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT02403310
A Study of Selinexor in Combination With Daunorubicin and Cytarabine for Untreated AMLtreatment1completed
NCT01034410
A Study of AS1411 Combined With Cytarabine in the Treatment of Patients With Primary Refractory or Relapsed Acute Myeloid Leukemiatreatment2terminated
NCT05457010
Phase I Study of Cell Therapies for the Treatment of Patients With Relapsed or Refractory AML or High-risk MDSNo drug interventionstreatment1recruiting
NCT04669210
PTCy and Ruxolitinib vs PTCy, Tacrolimus and MMF in MUD and Haploidentical HSCTprevention2active_not_recruiting
NCT03789981
Exploring Disease Immunogenicity and the Immunological Effects of Hypomethylating Agents in Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT04263181
AML/MDS Drug Sensitization by in Vivo Chemotherapy AdministrationNo drug interventionsNot AvailableNot Availablerecruiting
NCT00394381
Autologous Cytokine-induced Killer Cell Adoptive Immunotherapy for Acute Myeloid Leukemia and Myelodysplastic SyndromeNo drug interventionstreatment1 / 2completed
NCT01446081
An Exercise Trial for Acute Myeloid Leukaemia (AML) Patients Undergoing Induction ChemotherapyNo drug interventionssupportive_care2completed
NCT03381781
Decitabine,Cytarabine and Arsenic Trioxide for Acute Myeloid Leukemia With p53 Mutationstreatment2unknown_status
NCT03800095
Early Palliative Care for Patients With Haematological MalignanciesNo drug interventionstreatment3unknown_status
NCT01773395
GVAX vs. Placebo for MDS/AML After Allo HSCTtreatment2terminated
NCT03802695
A Phase 1 Study of Orca-Q in Recipients Undergoing Allogeneic Transplantation for Hematologic MalignanciesNo drug interventionstreatment1recruiting
NCT02337595
Memory T-cell Infusion to Improve Immunity After TCR-alpha/Beta Depleted Hematopoietic Stem Cell TransplantationNo drug interventionsprevention1 / 2completed
NCT04248595
Study of Azacitidine Combined With Homoharringtonie Based Regimens in AMLtreatment2unknown_status
NCT00466895
Lenalidomide in Acute Leukemias and Chronic Lymphocytic Leukemia.treatment1completed
NCT02341495
Deferasirox, Cholecalciferol, and Azacitidine in the Treatment of Newly Diagnosed AML Patients Over 65treatment2terminated
NCT01595295
Registry on Hypomethylating Agents in Myeloid NeoplasmsNo drug interventionsNot AvailableNot Availablecompleted
NCT00963495
Study Evaluating the Tolerance and Biological Activity of Oral Clioquinol in Patients With Relapsed or Refractory Hematological Malignancytreatment1terminated
NCT02750995
Peptide Vaccination in Combination With Azacitidine for Patients With MDS and AMLtreatment1completed
NCT00283114
A Safety Study of Lintuzumab in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrometreatment1completed
NCT05383014
FLT3-ITD Gene Mutation and CD135 Expression in Acute Myeloid Leukemia.No drug interventionsNot AvailableNot Availableunknown_status
NCT03197714
Clinical Trial of OPB-111077 in Patients With Relapsed or Refractory Acute Myeloid Leukaemiatreatment1completed
NCT01861314
Bortezomib, Sorafenib Tosylate, and Decitabine in Treating Patients With Acute Myeloid Leukemiatreatment1active_not_recruiting
NCT05943314
Clinical Study on Safety and Efficacy of Anti-CLL1 /+CD33 CAR T Cells in the Treatment of Acute Myeloid LeukemiaNo drug interventionstreatmentNot Availablewithdrawn
NCT02335814
First-in-Human Study of FLX925 in Subjects With Relapsed or Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1terminated
NCT00391014
Nebulized Liposomal Amphotericin B Ambisome for Prophylaxis of Invasive Pulmonary AspergillosisNo drug interventionsprevention2completed
NCT03121014
Study of Intensity Modulated Total Marrow Irradiation (IM-TMI) in Addition to Fludarabine/Busulfan Conditioning for Allogeneic Transplantation in High Risk AML and Myelodysplastic Syndromestreatment2active_not_recruiting
NCT05823714
Venetoclax+Azacytidine+Modified BUCY Conditioning Regimen for Acute Myeloid Leukemia and Myelodysplastic Syndromes Undergoing Allo-HSCTNo drug interventionstreatment2recruiting
NCT02561455
Rollover Study for Subjects Who Have Participated in an Astellas Sponsored ASP2215 Trialtreatment1 / 2completed
NCT00368355
T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Graftstreatment2completed
NCT00594555
A Study Evaluating the Effects of CLAG With Gleevec in Refractory or Relapsed Acute Myeloid Leukemiatreatment2withdrawn
NCT02400255
Crenolanib Maintenance Following Allogeneic Stem Cell Transplantation in FLT3-positive Acute Myeloid Leukemia Patientstreatment2completed
NCT00898755
Collecting and Storing Tissue From Young Patients With CancerNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02328755
Peginterferon Alfa-2a to Enhance Anti-leukemic Responses After Allogeneic Transplantation in Acute Myeloid Leukemiatreatment1 / 2completed
NCT00151255
All-Trans Retinoic Acid in Combination With Standard Induction and Consolidation Therapy in Older Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment3completed
NCT05266950
Safety and Efficacy Study of CI-135 CAR-T Cells in Subjects With Relapsed or Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1recruiting
NCT00458250
Feasibility of Haploidentical Hematopoietic Stem Cell Transplantation Using CAMPATH-1Htreatment1completed
NCT04190550
Testing the Addition of an Anti-cancer Drug, Navtemadlin, to the Usual Treatments (Cytarabine and Idarubicin) in Patients With Acute Myeloid Leukemiatreatment1active_not_recruiting
NCT02500550
Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donorprevention2completed
NCT00718250
Lentivirus Transduced Acute Myeloid Leukaemia Blasts Expressing B7.1 (CD80) and IL-2No drug interventionstreatment1unknown_status
NCT02435550
iCare for Cancer PatientsNo drug interventionsdiagnosticNot Availableterminated
NCT01683123
Study With Intravenous Busulfan And Fludarabine Myeloablative Conditioning Regimen For HLA Identical Sibling Donor HSCTNo drug interventionsNot AvailableNot Availablecompleted
NCT05297123
Treatment of Acute Myeloid Leukemia With Arsenic and All-trans Retinoid Acidtreatment1unknown_status
NCT03999723
Combining Active and Passive DNA HypomethylationNo drug interventionstreatment2recruiting
NCT03760523
Dose Escalation Study of Minnelide in Relapsed or Refractory Acute Myeloid Leukemiatreatment1terminated
NCT05471323
Phase I Clinical Trial of RC1012 Injection in Patients With r/r AMLNo drug interventionstreatment1recruiting
NCT01027923
IV Plerixafor With Mitoxantrone Etoposide and Cytarabine for Acute Myeloid Leukemia (AML)treatment1terminated
NCT06013423
Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseasestreatment2recruiting
NCT02676323
Panobinostat With Fludarabine and Cytarabine for Treatment of Children With Acute Myeloid Leukemia or Myelodysplastic Syndrometreatment1terminated
NCT04415008
Efficacy of HAD Induction With Intensified Cytarabine in Newly-diagnosed CEBPA Double Mutated Acute Myeloid Leukemiatreatment2recruiting
NCT05358808
ACHIEVE - Efficacy and Effectiveness of Adoptive Cellular tHerapy wIth Ex-Vivo Expanded Allogeneic γδ T-lymphocytes (TCB008) for Patients With Refractory or Relapsed Acute Myeloid Leukaemia (AML)treatment2recruiting
NCT03701308
Daunorubicin and Cytarabine With or Without Uproleselan in Treating Older Adult Patients With Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapytreatment2 / 3suspended
NCT02671708
IDA+BUCY vs BUCY Conditioning Regimen for Intermediate-risk AML Undergoing Auto-HSCTtreatment2 / 3completed
NCT02488408
A Phase Ib/II Multicenter Open-label Study of Bemcentinib (BGB324) in Patients With AML or MDStreatment1 / 2unknown_status
NCT01149408
Decitabine Maintenance in Elderly Acute Myeloid Leukemia Patientstreatment1completed
NCT04994808
Treosulfan-Based Versus Clofarabine-Based Conditioning Before Donor Hematopoietic Stem Cell Transplant for the Treatment of Myelodysplastic Syndromes or Acute Myeloid Leukemiatreatment2recruiting
NCT04789408
Study of KITE-222 in Participants With Relapsed/Refractory Acute Myeloid Leukemiatreatment1terminated
NCT06110208
Study to Evaluate the Safety and Preliminary Efficacy of CLL1 and CD38 Dual CAR-T in r/r AMLNo drug interventionstreatment0recruiting
NCT00691938
LBH589 Plus Decitabine for Myelodysplastic Syndromes (MDS) or Acute Myeloid Leukemia (AML)treatment1 / 2completed
NCT02073838
Ribavirin and Hedgehog Inhibitor With or Without Decitabine in AMLtreatment2completed
NCT04146038
Salsalate, Venetoclax, and Decitabine or Azacitidine for the Treatment of Acute Myeloid Leukemia or Advanced Myelodysplasia/Myeloproliferative Diseasetreatment2completed
NCT02678338
CAMELLIA: Anti-CD47 Antibody Therapy in Haematological Malignanciestreatment1completed
NCT04168138
D-CTAG in the Treatment of Newly Diagnosed Acute Myeloid Leukemia in Elderly PatientstreatmentNot Availablerecruiting
NCT02508038
Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumorstreatment1recruiting
NCT02873338
Dociparstat Sodium (CX-01) Combined With Standard Induction Therapy for Newly Diagnosed Acute Myeloid Leukemiatreatment2completed
NCT03072043
Phase 1b/2 Safety and Efficacy of APR-246 w/Azacitidine for tx of TP53 Mutant Myeloid Neoplasmstreatment1 / 2completed
NCT01297543
Safety Study of Human Myeloid Progenitor Cells (CLT-008) After Chemotherapy for Leukemiasupportive_care1 / 2completed
NCT05558943
Study of Management and Prognosis of Patients With Acute Myeloblastic Leukemia in Saint-Antoine HospitalNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02310243
Study of Palbociclib in MLL-rearranged Acute Leukemiastreatment1 / 2unknown_status
NCT02875743
King's Invasive Aspergillosis Study IIprevention4completed
NCT04599543
IL3 CAR-T Cell Therapy for Patients With CD123 Positive Relapsed and/or Refractory Acute Myeloid LeukemiaNo drug interventionstreatment0not_yet_recruiting
NCT03113643
SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)treatment1recruiting
NCT01222143
Safety and Efficacy Study of Nilotinib Combined With Mitoxantrone, Etoposide, and High-dose Cytarabine Induction Chemotherapy Followed by Consolidation for Patients With C-kit Positive Acute Myeloid Leukemiatreatment1 / 2terminated
NCT01001143
Intravenous (IV) Decitabine and Oral Bexarotene for Acute Myelogenous Leukemia (AML)treatment1completed
NCT02428543
Ponatinib for FLT3-ITD Acute Myelogenous Leukemiatreatment1 / 2unknown_status
NCT02775903
An Efficacy and Safety Study of Azacitidine Subcutaneous in Combination With Durvalumab (MEDI4736) in Previously Untreated Adults With Higher-Risk Myelodysplastic Syndromes (MDS) or in Elderly Patients With Acute Myeloid Leukemia (AML)treatment2completed
NCT01829503
Phase II Study of Decitabine and Cytarabine for Older Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)treatment2completed
NCT00048503
Study of Tipifarnib as Postconsolidation Therapy for Acute Myeloid Leukemia in Patients 60 Years and Oldertreatment2completed
NCT02093403
Decitabine and Selinexor in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemiatreatment1completed
NCT01494103
Administration of Donor T Cells With the Caspase-9 Suicide Genetreatment1active_not_recruiting
NCT02258490
Expanded Use of G-CSF Mobilized Donor CD34+ Selected Cells for Allogeneic TransplantationNot AvailableNot Availableno_longer_available
NCT03154190
Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With CancerNo drug interventionshealth_services_researchNot Availableunknown_status
NCT02283190
1336GCC: Study of Erwinaze for Treatment of Acute Myeloid Leukemia (AML)other1completed
NCT05791890
GilteRInf 2022 Study (Gilteritinib Related Infections)Not AvailableNot Availableactive_not_recruiting
NCT00669890
Allogenic Stem Cell Transplantation in Patients With High Risk CD33+ AML/MDS/JMMLtreatment1terminated
NCT04385290
Combination of Midostaurin and Gemtuzumab Ozogamicin in First-line Standard Therapy for Acute Myeloid Leukemia (MOSAIC)treatment1 / 2recruiting
NCT05382390
Dual Growth Factor (rhTPO + G-CSF) and Chemotherapy Combination Regimen in Acute Myeloid Leukemia: Study Protocol for a Randomized Controlled Trialtreatment3recruiting
NCT02834390
Study of Quizartinib in Japanese Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)treatment1completed
NCT02188290
Transplant-Related Mortality in Patients Undergoing a Peripheral Blood Stem Cell Transplantation or an Umbilical Cord Blood TransplantationNo drug interventionsNot AvailableNot Availablecompleted
NCT06323590
Refining the Role of Mid-induction Bone Marrow Biopsy in Acute Myeloid Leukemia: A Pilot StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT02714790
Prognostic Role of Minimal Residual Disease in Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT02027064
Interferon for the Intervention of Molecular Relapse in t (8; 21) AML After Allo-HSCTtreatment4unknown_status
NCT00480064
Lomustine and Intermediate Dose Cytarabine in Older Patients With AMLtreatment3completed
NCT03126864
Study of Adoptive Cellular Therapy Using Autologous T Cells Transduced With Lentivirus to Express a CD33 Specific Chimeric Antigen Receptor in Patients With Relapsed or Refractory CD33-Positive Acute Myeloid Leukemiatreatment1terminated
NCT02856464
Prophylactic DLI for the Prevention of Relapse Post HSCT in Patients With High Risk Myeloid MalignancyNo drug interventionstreatment2unknown_status
NCT03671564
Study of Milademetan in Japanese Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)treatment1completed
NCT04230564
Acute Myeloid Leukemia Real World Treatment PatternsNot AvailableNot Availablewithdrawn
NCT03306264
Study of ASTX727 vs IV Decitabine in Participants With MDS, CMML, and AMLtreatment3completed
NCT00968864
T-cell Depleted Alternative Donor TransplantationNo drug interventionstreatment2terminated
NCT03597321
Early Prophylactic Donor Lymphocyte Infusion After Allo-HSCT for Patients With AMLNo drug interventionstreatment2unknown_status
NCT06055621
Evaluation of DASATINIB Monotherapy Efficacy in Acute Myeloid Leukemia Patients Refractory to VENETOCLAX-AZACITIDINEtreatment2not_yet_recruiting
NCT06557421
De-Escalation Study Evaluating Venetoclax and Azacitidine Discontinuation in AML Responding Patientstreatment2not_yet_recruiting
NCT04580121
A Dose Escalation and Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7283420.treatment1completed
NCT06068621
Clinical Study of Venetoclax Combined With CACAG Regimen in the Treatment of Newly Diagnosed Acute Myeloid Leukemiatreatment2recruiting
NCT03715621
Prognostic Values of Next Generation Sequencing (NGS) in Acute Myeloid Leukemia Patients With Allo-HSCTNo drug interventionsNot AvailableNot Availableunknown_status
NCT01035502
A Study of Elacytarabine (CP-4055) Plus Idarubicin as Second Course Remission-Induction Therapy in Patients With Acute Myeloid Leukaemiatreatment2completed
NCT02863302
Reflexology: An Intervention for Acute Myeloid Leukemia(AML) PatientsNo drug interventionssupportive_careNot Availableunknown_status
NCT03454984
SGI-110 and Donor Lymphocyte Infusions (DLI) After Allogeneic Stem Cell Transplantationprevention2unknown_status
NCT01277484
Dose Finding Study of Post-BMT Decitabine Maintenance Treatment in Higher-risk MDS and MDS/AMLtreatment1unknown_status
NCT00615784
Phase II Study of Bexarotene in Patients With Acute Myeloid Leukemiatreatment2terminated
NCT05603884
VCA Regimen Followed by D-MAG Regimen on the Treatment of Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)treatment2recruiting
NCT02717884
Study of Sensitization of Non-M3 AML Blasts to ATRA by Epigenetic Treatment With Tranylcypromine (TCP)treatment1 / 2unknown_status
NCT06551584
Phase I Trial for Patients w/ Advanced Hematologic Malignancies Undergoing Allogeneic HCTtreatment1not_yet_recruiting
NCT05263284
8-Chloroadenosine in Combination With Venetoclax for the Treatment of Patients With Relapsed/Refractory Acute Myeloid Leukemiatreatment1recruiting
NCT00697684
Reduced Intensity Conditioning With Clofarabine, Antithymocyte Globulin (ATG), Total Lymphoid Irradiation (TLI) Followed by Allogeneic Stem Cell Transplanttreatment1completed
NCT02732184
A Multiple Dose, Dose Escalation Trial of AEB1102 in Patients With AML or MDStreatment2completed
NCT03023384
Feasibility Study of Intermediate Doses of ARA-C With Autologous SCT as Consolidation of Low/Intermediate-risk AMLNo drug interventionsNot AvailableNot Availableunknown_status
NCT06441084
A Trial to Evaluate the Safety and Efficacy of NCR300 in Preventing Recurrence of Acute Myeloid Leukemia(AML) After TransplantationNo drug interventionsprevention1not_yet_recruiting
NCT03724084
Pinometostat With Standard Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and MLL Gene Rearrangementtreatment1 / 2terminated
NCT04450784
ObServatory Children Acute RElated Therapy LeukemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT05735184
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, or 7+3 in Patients With AMLtreatment1recruiting
NCT04635384
Assessment of Chimerism and Relapse Post Bone Marrow/Hematopoietic Cell Transplant (HCT) Using AlloHeme TestNo drug interventionsNot AvailableNot Availablerecruiting
NCT03416179
A Study Evaluating Intensive Chemotherapy With or Without Glasdegib or Azacitidine With or Without Glasdegib In Patients With Previously Untreated Acute Myeloid Leukemiatreatment3completed
NCT00101179
MS-275 and Azacitidine in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemiatreatment1completed
NCT01307579
Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemiasupportive_care3completed
NCT00674479
INCB018424 in Patients With Advanced Hematologic Malignanciestreatment2completed
NCT04028479
The Registry of Oncology Outcomes Associated With Testing and TreatmentNo drug interventionsNot AvailableNot Availablerecruiting
NCT04353479
Combined PD1 Inhibitor and Decitabine in Elderly Patients With Relapse and Refractory Acute Myeloid Leukemiatreatment2unknown_status
NCT04229979
Galinpepimut-S Versus Investigator's Choice of Best Available Therapy for Maintenance in AML CR2/CRp2treatment3active_not_recruiting
NCT00569179
A Phase I Trial of Alloreactive Cell Infusion Following Transplantation of Haplotype Cells in Patients With Myeloid MalignanciesNo drug interventionstreatment1terminated
NCT02543879
Study of a Novel BET Inhibitor FT-1101 in Patients With Relapsed or Refractory Hematologic Malignanciestreatment1completed
NCT00766779
HCT Versus CT in Elderly AMLNo drug interventionstreatment3terminated
NCT06328179
Clinical Study Protocol for the Treatment of ND-AML and RR-AML With KMT2A Gene Abnormalities Using VHEA.treatmentNot Availablerecruiting
NCT00480987
Oxaliplatin, Fludarabine, and Cytarabine in Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndromes (MDS)treatment1 / 2terminated
NCT04282187
Decitabine With Ruxolitinib, Fedratinib or Pacritinib for the Treatment of Accelerated/Blast Phase Myeloproliferative Neoplasmstreatment2recruiting
NCT03595787
COaching and Prehabilitation: Faisability Study in Patients With Acute Myeloid Leukemia and Myelodysplastic SyndromeNo drug interventionssupportive_careNot Availablerecruiting
NCT01835587
Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS).treatment1 / 2completed
NCT06138587
Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantationtreatment1recruiting
NCT03825887
Nalbuphine Versus Morphine for Mucositis Pain in Pediatric Cancer Patientsprevention3completed
NCT01926587
Phase II Part 2 Expansion of Oral Rigosertib in Combination With Azacitidinetreatment1 / 2completed
NCT02602587
Study of Dendrogenin A / Oxysterols Balance Between Healthy Volunteers and Acute Myeloid Leukemia PatientsNo drug interventionsbasic_scienceNot Availablecompleted
NCT03008187
SEL24/MEN1703 in Patients With Acute Myeloid Leukemiatreatment1 / 2completed
NCT03156933
Alternative Splicing and Leukemia Initiating CellsNo drug interventionsNot AvailableNot Availableunknown_status
NCT04173533
Randomised Study of Oral Azacitidine vs Placebo Maintenance in AML or MDS Patients After Allo-SCTtreatment3active_not_recruiting
NCT02933333
G-CSF Alone or Combination With GM-CSF on Prevention and Treatment of Infection in Children With Malignant Tumortreatment4unknown_status
NCT01203033
Prospective Pilot Study of Bone Marrow and Peripheral Blood Samples From AML Patients to Characterize the Biologic Heterogeneity of the Disease Using Single Cell Network Profiling (SCNP)No drug interventionsNot AvailableNot Availablecompleted
NCT01802333
Cytarabine and Daunorubicin Hydrochloride or Idarubicin and Cytarabine With or Without Vorinostat in Treating Younger Patients With Previously Untreated Acute Myeloid Leukemiatreatment3completed
NCT05309733
A Long-term Follow-up Study of Patients Who Received VOR33No drug interventionsNot AvailableNot Availablerecruiting
NCT02789254
FLYSYN in MRD Positive AMLNo drug interventionstreatment1 / 2completed
NCT00990054
Study of Plerixafor Combined With Cytarabine and Daunorubicin in Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment1completed
NCT02750254
Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantationtreatment1terminated
NCT01578954
Lenalidomide as Consolidation and Maintenance in Adults >/= 60 Years of Age With AML Following Standard Inductiontreatment1completed
NCT03083054
Cellular Immunotherapy for Patients With High Risk Myelodysplastic Syndromes and Acute Myeloid LeukemiaNo drug interventionstreatment1 / 2unknown_status
NCT05028751
A Study to Evaluate Lanraplenib (LANRA) in Combination With Gilteritinib in Participants With FLT3-mutated Relapsed or Refractory Acute Myeloid Leukemia (AML)treatment1 / 2terminated
NCT01588951
Consolidation Therapy for Acute Myeloid Leukemia Guided by Leukemia Stem Cell Behaviortreatment2 / 3terminated
NCT01700751
Brentuximab Vedotin Prevention of (GVHD) After Unrelated Allogeneic Stem Cell Transplantationtreatment1completed
NCT02743351
Study of ProTmune for Allogeneic HCT in Adult Patients With Hematologic MalignanciesNo drug interventionsprevention1 / 2completed
NCT00038051
Evaluation of the Anti-CD-33 Immunotoxin Hum-195/rGel in Patients With Advanced Myeloid MalignanciesNo drug interventionstreatment1completed
NCT06297551
Acute Myeloid Leukemia and Markers of Leukemia Stem Cells (CLL1 and CD45RA)No drug interventionsNot AvailableNot Availablerecruiting
NCT02861651
Molecular Characterization of Acute Erythroid Leukemia (M6-AML) Using Targeted Next-generation SequencingNo drug interventionsNot AvailableNot Availablecompleted
NCT05101551
Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacytreatment1recruiting
NCT00783653
Clinical Study of SU 11248 (Sutent) Combined With Standard Chemotherapy in Patients With FLT3 Mutated AML Over 60 Yearstreatment1 / 2completed
NCT01146977
Autologous Hematopoietic Cell Transplantation for Core-binding Factor (CBF) Acute Myeloid Leukemia (AML) in the First Complete Remission (CR1)No drug interventionstreatment2unknown_status
NCT02038777
A Study Of PF-04449913 In Japanese Patients With Select Hematologic Malignanciestreatment1completed
NCT02914977
Low-Dose Daunorubicin in Relapsed/Refractory Acute Leukemiatreatment1completed
NCT02450877
A Study of Safety, Efficacy and Pharmacodynamics of Azacitidine in Children and Young Adults With Acute Myeloid Leukemia.treatment2completed
NCT02877277
Epigenetics, Vitamin C and Abnormal Hematopoiesis - Pilot StudyNo drug interventionstreatmentNot Availablecompleted
NCT04010877
Multiple CAR-T Cell Therapy Targeting AMLNo drug interventionstreatment1 / 2unknown_status
NCT05330377
GM-CLAG in Relapsed/Refractory FLT3-mutated AMLtreatment1withdrawn
NCT05972577
Geriatric Optimization Plan to Improve Survival in Older Adult Allogeneic Hematopoietic Cell Transplant Candidates, OTIS StudyNo drug interventionssupportive_careNot Availableactive_not_recruiting
NCT04060277
Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantationsupportive_care2active_not_recruiting
NCT01382147
Evaluation of "Dose-dense Therapy" by S-HAM in Comparison to Conventionally Timed Double Induction in Patients With Acute Myeloid Leukemia (AML)treatment3completed
NCT01573247
Safety Study of AKN-028 in Patients With Acute Myelogenous Leukemiatreatment1 / 2terminated
NCT00460447
Gemtuzumab Ozogamicin Before Allogeneic Stem Cell Transplantationtreatment1 / 2unknown_status
NCT01499147
Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic MalignanciestreatmentNot Availablecompleted
NCT04227847
A Safety Study of SEA-CD70 in Patients With Myeloid Malignanciestreatment1recruiting
NCT05061147
A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of Max-40279-01 in Combination With Azacitidine (AZA) in Patients With Myelodysplastic Syndrome (MDS) or Relapsed/Refractory Acute Myeloid Leukemia (R/R AML)treatment1 / 2unknown_status
NCT00199147
Efficacy of G-CSF-Priming in Elderly AML Patientstreatment4unknown_status
NCT02527447
Biomarkers for Personalized Early Assessment of Response During Salvage Chemotherapy in People With Relapsed or Refractory Acute Myeloid Leukemia (PEARL15)No drug interventionsNot AvailableNot Availablecompleted
NCT00849147
Bone Marrow Transplant From Partially Matched Donors and Nonmyeloablative Conditioning for Blood Cancers (BMT CTN 0603)No drug interventionstreatment2completed
NCT00946647
A Phase Ib/IIb, Open-label, Multi-center, Study of Oral Panobinostat Administered With 5-Azacitidine (in Adult Patients With Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML).treatment1 / 2completed
NCT04075747
A Phase 1b Master Trial to Investigate CPX-351 in Subjects With Previously Untreated Acute Myeloid Leukemiatreatment1completed
NCT03921047
Characterization of T-cell Repertoire in Patients With Acute Myeloid Leukemia Undergoing Donor Stem Cell TransplantNo drug interventionsNot AvailableNot Availablerecruiting
NCT02277847
Idarubicin at Different Dosages as Induction Therapy for Newly Diagnosed Acute Myeloid Leukaemiatreatment4unknown_status
NCT01350245
Bone Marrow Transplantation of Patients in Remission Using Partially Matched Relative Donortreatment2completed
NCT00854945
Study of 72-Hour Infusion of ON 01910.Na in Patients With MDS or AMLtreatment1 / 2completed
NCT02472145
An Efficacy and Safety Study of Decitabine (DACOGEN) Plus Talacotuzumab (JNJ-56022473; Anti CD123) Versus Decitabine (DACOGEN) Alone in Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapytreatment2 / 3completed
NCT02446145
A Randomized Placebo-controlled Phase 2 Study of Decitabine With or Without Eltrombopag in AML Patientstreatment2terminated
NCT03144245
Study of AMV564 in Patients With AMLtreatment1completed
NCT00593645
Clofarabine, Cytarabine, and Thymoglobulin for Allogeneic Transplantationtreatment2terminated
NCT00906945
Chemosensitization With Plerixafor Plus G-CSF in Acute Myeloid Leukemiatreatment1 / 2completed
NCT05805098
Venetoclax Combined With Homoharringtonine and Cytarabine in Induction for AMLtreatment2 / 3recruiting
NCT05918198
Clinical Study of Venetoclax Combined With CAG in the Treatment of Refractory/Relapsed Acute Myeloid Leukemiatreatment2recruiting
NCT00629798
Busulfan, Melphalan, and Fludarabine With Peri-transplant Palifermin, Followed by a T-Cell Depleted Hematopoietic Stem Cell Transplant From HLA Matched or Mismatched Related or Unrelated Donors in Patients With Advanced Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)treatment2completed
NCT02860598
Observatory of the Prescription of Erythropoietin as Treatment of Anemia Induced by Chemotherapy or Allograft Conditioning Among the Patients With a Haematological MalignancyNo drug interventionsNot AvailableNot Availableunknown_status
NCT03953898
Using the Anticancer Drug Olaparib to Treat Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome With an Isocitrate Dehydrogenase (IDH) Mutationtreatment2active_not_recruiting
NCT00416598
Decitabine as Maintenance Therapy After Standard Therapy in Treating Patients With Previously Untreated Acute Myeloid Leukemiatreatment2completed
NCT05565105
CD34+ Transplants for Leukemia and Lymphomatreatment2not_yet_recruiting
NCT05875805
A Telehealth Advance Care Planning InterventionNo drug interventionssupportive_careNot Availablerecruiting
NCT00513305
Cytarabine in Combination With Arsenic Trioxide vs. Cytarabine Alone in Elderly Patients With Acute Myeloid Leukemiatreatment3terminated
NCT04512105
Pitavastatin in Combination With Venetoclax for Chronic Lymphocytic Leukemia or Acute Myeloid Leukemiatreatment1active_not_recruiting
NCT03426605
A Study of LAM-003 in Patients With Acute Myeloid LeukemiaNo drug interventionstreatment1completed
NCT06008405
Clinical Trial Evaluating the Safety of the TQB2928 Injection Combination Therapytreatment1recruiting
NCT04093505
Gemtuzumab Ozogamicin in Induction and Glasdegib in Postremission Therapy in Patients With AML (Acute Myeloid Leukemia)treatment3terminated
NCT03148197
Changes in the Gut Microbiota of Patients Undergoing Allogeneic Stem Cell Transplantation (COLLECT)No drug interventionsNot AvailableNot Availableunknown_status
NCT04068597
Study to Evaluate CCS1477 in Haematological Malignanciestreatment1 / 2recruiting
NCT05748197
A Study of ADCLEC.syn1 in People With Acute Myeloid LeukemiaNo drug interventionstreatment1recruiting
NCT00607997
Study of Voreloxin (Vosaroxin) in Older Patients With Untreated Acute Myeloid Leukemiatreatment2completed
NCT03844997
Phase I/II Trial of CPX-351 + Palbociclib in Patients With Acute Myeloid Leukemiatreatment1 / 2active_not_recruiting
NCT02771197
Lymphodepletion and Anti-PD-1 Blockade to Reduce Relapse in AML Patient Not Eligible for Transplanttreatment2completed
NCT03301597
NLA101 in Adults Receiving High Dose Chemotherapy for AMLprevention2terminated
NCT05401097
IDH Targeted/Non- Targeted vs Non-targeted/IDH-targeted Approaches in the Treatment of Newly Diagnosed IDH Mutated AML Patients Not Candidates for Intensive Induction Therapy (I- DATA Study)treatment2recruiting
NCT04778397
Study of Magrolimab in Combination With Azacitidine Versus Physician's Choice of Venetoclax in Combination With Azacitidine or Intensive Chemotherapy in Patients With TP53 Mutant Acute Myeloid Leukemia That Have Not Been Treatedtreatment3terminated
NCT02545283
A Study of Idasanutlin With Cytarabine Versus Cytarabine Plus Placebo in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML)treatment3terminated
NCT05017883
TAA05 Cell Injection in the Treatment of Recurrent / Refractory Acute Myeloid LeukemiaNo drug interventionstreatmentNot Availablerecruiting
NCT05201183
A Dose Escalation Study of Intensity Modulated Total Marrow Irradiation (IMRT-TMI) Followed by Fludarabine as a Myeloablative Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Relapsed and Refractory Hematologic Malignanciestreatment1 / 2withdrawn
NCT05264883
Venetoclax+HMA+Aclarubicin Versus Venetoclax+HMA in Treatment-Naive Elderly Patients With AMLtreatment3recruiting
NCT00037583
Study Evaluating the Safety and Efficacy of Gemtuzumab Ozogamicin in Patients With Acute Myeloid Leukemiatreatment2completed
NCT02101983
Pilot Study of Feasibility of Outpatient Daily High Dose Cytarabine as Consolidation Therapy for Older Patients With Acute Myeloid Leukemia (AML)treatmentNot Availablecompleted
NCT05580861
Sulfasalazine in AML Treated by Intensive Chemotherapy: Elderly Patients-first Line Treatmenttreatment1 / 2recruiting
NCT05150561
Muscle Dysfunction in Patients With Haematological DiseasesNo drug interventionsNot AvailableNot Availableunknown_status
NCT00989261
Efficacy Study for AC220 to Treat Acute Myeloid Leukemia (AML)treatment2completed
NCT04687761
Clinical Trial to Assess the Safety and Tolerability of the Combination of Low-dose Cytarabine or Azacitidine Plus Venetoclax and Quizartinib in Newly Diagnosed AML Patients Aged Equal or More Than 60 Years Oldtreatment1 / 2recruiting
NCT02308761
A Study of RO6870810/TEN-010 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndrometreatment1completed
NCT06451861
Randomized Study of ABC-14 Regimen Compared With "3+7" Standard Induction Therapy or AB-14 for ND AMLtreatment2not_yet_recruiting
NCT06384261
A Study Comparing Venetoclax and Azacitidine Plus Cusatuzumab to Venetoclax and Azacitidine in Newly Diagnosed AML Ineligible for Intensive Therapytreatment2recruiting
NCT04024761
A Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Hematopoietic Cell Transplantationtreatment1enrolling_by_invitation
NCT00462761
A Phase I Study of AC220 in Patients With Relapsed/Refractory Acute Myeloid Leukemia Regardless of FLT3 Statustreatment1completed
NCT04185428
Investigating Integrative Therapies for Symptom Management in Adults With Acute LeukemiaNo drug interventionssupportive_careNot Availablesuspended
NCT05995028
Universal 4SCAR7U Targeting CD7-positive MalignanciesNo drug interventionstreatment1recruiting
NCT05170828
Cryopreserved MMUD BM With PTCy for Hematologic Malignanciestreatment1withdrawn
NCT03843528
Vorinostat Dose-escalation After Allogeneic Hematopoietic Cell Transplantationtreatment1recruiting
NCT03634228
Milademetan Tosylate and Low-Dose Cytarabine With or Without Venetoclax in Treating Participants With Recurrent or Refractory Acute Myeloid Leukemiatreatment1 / 2terminated
NCT03135028
Entospletinib (ENTO) as Monotherapy and in Combination With Chemotherapy in Japanese Adultstreatment1terminated
NCT06158828
Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AMLtreatment1 / 2recruiting
NCT06225128
Dynamics of Resistance Emergence to Azacitidine-based Therapies in Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT03287128
Retrospective Analysis of the Outcome of Patients With Relapsed/Refractory Acute Myeloid Leukemia Included in a Patient Named Program of Gemtuzumab Ozogamicin/Mylotarg®Not AvailableNot Availableunknown_status
NCT04763928
Trial in AML Secondary to MPNs Patients, Unfit for Intensive Chemotherapy, Investigating a Treatment Combination Including Decitabine and Venetoclaxtreatment2unknown_status
NCT03674411
Trial Evaluating MGTA-456 in Patients With High-Risk Malignancytreatment2active_not_recruiting
NCT01685411
Busulfan and Cyclophosphamide Followed By ALLO BMTtreatmentNot Availableterminated
NCT02520011
Alvocidib Biomarker-driven Phase 2 AML Studytreatment2terminated
NCT01238211
Combination Chemotherapy and Dasatinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment2completed
NCT01688011
Connect® Myeloid Disease RegistryNot AvailableNot Availablerecruiting
NCT01519011
Study to Evaluate Pharmacokinetics, Food Effect, Safety and Efficacy of Oral Azacitidinetreatment1completed
NCT05445011
Anti-FLT3 CAR-T Cell (TAA05 Cell Injection) in the Treatment of Relapsed / Refractory Acute Myeloid Leukemiatreatment1recruiting
NCT02743611
Safety & Activity of Controllable PRAME-TCR Therapy in Previously Treated AML/MDS or Metastatic Uveal Melanomatreatment1 / 2terminated
NCT02432911
Treatment of Elderly Chinese Acute Myeloid Leukemia Patients Aged 65 to 75 Years OldtreatmentNot Availableunknown_status
NCT02072811
Role of the Therapy Tailored to Risk Factors in Treating Adult Patients (≤60) With Acute Myeloid Leukemiatreatment3unknown_status
NCT04083911
Study of DAC Combined With HAAG Regimen in Newly Diagnosed AML Patients Older Than 60treatment3unknown_status
NCT01898793
Cytokine-induced Memory-like NK Cells in Patients With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)treatment1 / 2terminated
NCT05334693
Expanded Haploidentical Natural Killer Cells as Consolidation Strategy for Children/Young Adults With AMLtreatment1 / 2recruiting
NCT02667093
Samples From Leukemia Patients and Their Donors to Identify Specific AntigensNo drug interventionsNot AvailableNot Availableunknown_status
NCT02860793
Role of PTK-7 in Acute Myeloid LeukemiasNo drug interventionsbasic_scienceNot Availablecompleted
NCT01247493
Modified-FLAI Induction and Consolidation Chemotherapy in Elderly Patient With Acute Myeloid Leukemia (AML)treatment2completed
NCT00822393
Clinical Phase III Trial Treosulfan-based Conditioning Versus Reduced-intensity Conditioning (RIC)treatment3completed
NCT02686593
Clofarabine, Cytarabine and Mitoxantrone (CLAM) for Relapsed or Refractory AMLtreatment2completed
NCT02875093
Ph 1 Study of ADI-PEG 20 Plus Low Dose Cytarabine in Older Patients With AMLtreatment1terminated
NCT02521493
Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrometreatment3active_not_recruiting
NCT03678493
A Study of FMT in Patients With AML Allo HSCT in Recipientstreatment2completed
NCT01484171
HLA-mismatched Microtransplantation for High Risk Acute Myeloid Leukemiatreatment3unknown_status
NCT03256071
Low Dose Decitabine + Modified BUCY Conditioning Regimen for High Risk Acute Myeloid Leukemia Undergoing Allo-HSCTtreatment2 / 3unknown_status
NCT03439371
Micro-transplantation in Elderly Patients With Acute Myeloid LeukemiaNo drug interventionstreatmentNot Availablerecruiting
NCT06218771
A Study of TQB3454 Tablets in Patients With Blood TumorsNo drug interventionstreatment1 / 2recruiting
NCT00542971
Phase I-II Study of Idarubicin, Cytarabine, and Sorafenib (BAY43-9006)treatment1 / 2completed
NCT01329471
Functional Role of RUNX1 Mutations in the Etiology of Acute Myeloid Leukemia (AML)No drug interventionsNot AvailableNot Availableunknown_status
NCT03793478
Safety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Bloodtreatment1 / 2recruiting
NCT04951778
Study to Evaluate Safety and Tolerability of CC-91633 (BMS-986397) in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher-Risk Myelodysplastic SyndromesNo drug interventionstreatment1recruiting
NCT02349178
Bridging Study to Eliminate Presence of MRD for Acute Leukemia Before HCTtreatment2terminated
NCT01025778
Haploidentical Stem Cell Transplantation for Children With Therapy Resistant Leukemiatreatment2completed
NCT04872478
Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPALNo drug interventionstreatment1recruiting
NCT05720988
Tagraxofusp to Eradicate Measurable Residual Disease in Patients With Acute Myeloid Leukemiatreatment1withdrawn
NCT02270788
Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignanciestreatment1completed
NCT03187288
Study of CFI-400945 Fumarate in Patients With Relapsed or Refractory AML or MDStreatment1completed
NCT05587088
Evaluation of the Safety and Efficacy of Esperanza Extract (PA001)No drug interventionstreatment1 / 2not_yet_recruiting
NCT04526288
CPX-351 Versus Immediate Stem Cell Transplantation for the Treatment of High-Grade Myeloid Cancers With Measurable Residual Diseasetreatment2terminated
NCT03564288
Study to Find a Safe and Effective Dose of SKI-G-801 in the Treatment of Patients With Acute Myeloid Leukemia (AML)No drug interventionstreatment1completed
NCT06001788
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemiatreatment1recruiting
NCT01174888
Phase I Combination of Midostaurin, Bortezomib, and Chemo in Relapsed/Refractory Acute Myeloid Leukemiatreatment1completed
NCT03515707
Stem Cell Transplant to Treat Patients With Favorable or Intermediate Risk Minimal Residual Disease Negative Acute Myeloid Leukemiatreatment2withdrawn
NCT06445907
Phase I Study of Q702 With Azacitidine and Venetoclax for Relapsed or Refractory Acute Myeloid Leukemiatreatment1not_yet_recruiting
NCT04905407
Tamibarotene Plus Venetoclax/Azacitidine in Participants With Newly Diagnosed AMLtreatment2active_not_recruiting
NCT03410407
Central Nervous System (CNS) Involvement in Acute Myeloid Leukemia (AML)No drug interventionsNot AvailableNot Availableterminated
NCT01889407
Idarubicin Overcomes MDR1 Induced Chemoresistance With Higher Induction Remission Rate and Quality Than Daunorubicin in Acute Myeloid Leukemia PatientsNot AvailableNot Availableunknown_status
NCT01660607
Phase 1-2 MAHCT w/ TCell Depleted Graft w/ Simultaneous Infusion Conventional and Regulatory T CellNo drug interventionstreatment1 / 2completed
NCT05169307
CPX-351 Real-World Effectiveness and Safety StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT05563207
Application of Health Education Path of Traditional Chinese Medicine NursinNo drug interventionssupportive_careNot Availablecompleted
NCT05716009
Tagraxofusp-erzs, an IL-3 Diphtheria Fusion Protein, in Combination With Gemtuzumab Ozogamicin in Patients With Relapsed/Refractory AMLtreatment1recruiting
NCT01036009
A Study of Withdrawal of Immunosuppression and Donor Lymphocyte Infusions Following Allogeneic Transplant for Pediatric Hematologic MalignanciesNo drug interventionstreatment2completed
NCT03088709
Haploidentical Stem Cell Transplantation Using Post-Transplant Cyclophosphamideprevention2terminated
NCT04637009
A Study of TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid NeoplasmsNo drug interventionstreatment1terminated
NCT03503409
IDH1 (AG 120) Inhibitor in Patients With IDH1 Mutated Myelodysplastic Syndrometreatment2active_not_recruiting
NCT03586609
Venetoclax, Cladribine, Low Dose Cytarabine, and Azacitidine in Treating Patients With Previously Untreated Acute Myeloid Leukemiatreatment2recruiting
NCT05155709
A Study of Siremadlin in Combination With Venetoclax Plus Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Chemotherapy.treatment1completed
NCT00900809
QUILT-3.018: Neukoplast™ (NK-92) for the Treatment of Refractory or Relapsed Acute Myeloid Leukemiatreatment1completed
NCT05107856
PRT1419 as Monotherapy or in Combination With Azacitidine or Venetoclax in R/R Myeloid or B-cell Malignanciestreatment1terminated
NCT02676856
Hematopoietic Stem Cell Microtransplantation for in AMLNo drug interventionstreatmentNot Availableunknown_status
NCT01518556
Safety and Efficacy Study of Idarubicin Dose Intensification to Treat Acute Myeloid Leukemiatreatment1 / 2active_not_recruiting
NCT00539656
Transplantation of Umbilical Cord Blood Following Chemotherapy for Blood CancersNo drug interventionstreatment1 / 2terminated
NCT06133556
Conditioning Regimen Containing Melphalan and Cladribine for Refractory / Relapsed AMLNo drug interventionstreatment2not_yet_recruiting
NCT05506956
Post-transplant Flotetuzumab for AMLtreatment1completed
NCT02367456
A Combination Study of PF-04449913 (Glasdegib) and Azacitidine In Untreated MDS, AML and CMML Patientstreatment1completed
NCT02878785
Decitabine and Talazoparib in Untreated AML and R/R AMLtreatment1 / 2completed
NCT04022785
PLX51107 and Azacitidine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrometreatment1completed
NCT00957385
Maintenance Therapy in Acute Myeloid Leukemia (AML) Patientstreatment2completed
NCT01951885
Tac, Mini-MTX, MMF Versus Tac, MTX for GVHD Preventionsupportive_care3completed
NCT04173585
TEAM-Trial: Targeting Epigenetic Therapy Resistance in AML With Bortezomibtreatment2completed
NCT04679285
Minimal Residual Disease Evaluation on Cryopreserved Ovarian Fragments in Younger Patients Treated for Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT04013685
Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic MalignanciesNo drug interventionstreatment1active_not_recruiting
NCT04060485
Screening Gene Mutations in Myeloid Cancers by Next Generation Sequencing to Improve Treatment ResultsNo drug interventionsNot AvailableNot Availablerecruiting
NCT06001385
HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxistreatment2recruiting
NCT04762485
Humanized CD7 CAR T-cell Therapy for r/r CD7+ Acute LeukemiaNo drug interventionstreatment1 / 2unknown_status
NCT00915785
Azacytidine for the Treatment of Myelodysplastic Syndromes/Acute Myeloid Leukemia (MDS/AML) With High Risk (Chromosome 7 and or Complex) Cytogenetic Abnormalitiestreatment2completed
NCT04002115
Clofarabine Pre-conditioning Followed by Stem Cell Transplant for Non-remission AMLtreatment2terminated
NCT02345915
Evaluation of Adverse Long-term Effects in Young Adult Survivors of Acute LeukemiaNo drug interventionsbasic_scienceNot Availableunknown_status
NCT03311815
Diagnostic Platform to Perform Centralized and Standardized Rapid Molecular Diagnosis by Next Generation Sequencing (NGS) in Patients Diagnosed With Acute Myeloid Leukemia.No drug interventionsNot AvailableNot Availablecompleted
NCT00242515
T-cell Depleted Donor Lymphocyte Infusion (DLI)for Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)No drug interventionstreatment1 / 2unknown_status
NCT03690115
Study of Ponatinib (Iclusig) for Prevention of Relapse After Allogeneic Stem Cell Transplantation (Allo-SCT) in FLT3-ITD AML Patientstreatment2active_not_recruiting
NCT03263637
Study to Assess Safety, Tolerability, Pharmacokinetics and Antitumor Activity of AZD4573 in Relapsed/Refractory Haematological Malignanciestreatment1completed
NCT06378437
A Study of GLB-001 in Patients With Myeloid MalignanciesNo drug interventionstreatment1recruiting
NCT01390337
A Study to Assess AC220 Given in Combination With Induction and Consolidation Therapy in Newly Diagnosed Acute Myeloid Leukemia (AML)treatment1completed
NCT01994837
A Phase 2 Study of ABT-199 in Subjects With Acute Myelogenous Leukemia (AML)treatment2completed
NCT00328237
Treatment of Hematologic Malignancies With Single-Unit or Double-Unit Cord Blood TransplantationNo drug interventionstreatment2unknown_status
NCT02461537
Impact of Remission Induction Chemotherapy Prior to Allogeneic SCT in Relapsed and Poor-response Patients With AMLtreatment3completed
NCT00260832
Trial of Decitabine in Patients With Acute Myeloid Leukemiatreatment3completed
NCT03374332
Fractionated Gemtuzumab Ozogamicin Followed by Non-engraftment Donor Leukocyte Infusions for Relapsed/Refractory Acute Myeloid Leukemiatreatment2active_not_recruiting
NCT02845232
Economic Analysis of Blood Product Transfusions According to the Treatment of Acute Myeloid Leukaemia in the ElderlyNo drug interventionsNot AvailableNot Availablecompleted
NCT00762632
Combination of Nilotinib (AMN107) and RAD001 in Patients With Acute Myeloid Leukemiatreatment1 / 2completed
NCT05433532
Study of Azacitidine,Venetoclax,and Flumatinib in Newly Diagnosed Ph-positive Acute Leukemia and CML-AP/BP Patientstreatment2completed
NCT06286332
Music Therapy in Acute Leukemia Patients With FatigueNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT06452732
Using Multiparametric Flow Cytometry to Detect Peripheral Blood and Bone Marrow Leukaemia Stem Cells for Relapse Prediction in P-AMLNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04722952
PD-1 Inhibitor Combined With Azacytidine and Homoharringtonine,Cytarabine, G-CSF for Refractory or Relapsed AMLtreatment3unknown_status
NCT03823352
Evaluate Efficacy and Safety/Tolerability Profiles of Antroquinonol in Acute Myeloid Leukemia (AML) Adult Patientstreatment2completed
NCT02598752
Feasibility and Safety of Functional Performance Testing in Patients Undergoing Hematopoietic Cell TransplantationNo drug interventionsNot AvailableNot Availablecompleted
NCT01656252
Trial of Eltrombopag During Consolidation Therapy in Adults With AML in Complete Remissiontreatment1 / 2terminated
NCT01246752
Haematopoietic Stem Cell Transplantation (HSCT) in Comparison to Conventional Consolidation Therapy for Patients With Acute Myeloid Leukemia (AML) (Intermediate Risk) </= 60y. After First CRtreatment3terminated
NCT00637052
A Study of ARRY-520 in Patients With Advanced Myeloid Leukemiatreatment1 / 2completed
NCT01632852
A Study of CSL362 in Patients With CD123+ Acute Myeloid Leukemia Currently in Remissiontreatment1completed
NCT04485052
Efficacy and Safety Evaluation of IBI188 in Combination With Demethylating Agents in Treatment of Patients With Acute Myeloid Leukemiatreatment1 / 2suspended
NCT03350152
Treatment With Low-Dose Cytarabine in Elderly Patients (Age 70 Years or Older) With Acute Myeloid Leukemia: A Single Institution Experience.No drug interventionsNot AvailableNot Availablecompleted
NCT00512252
AMD3100 Plus Mitoxantrone, Etoposide and Cytarabine in Acute Myeloid Leukemiatreatment1 / 2completed
NCT02410252
Use Feasibility of the iThermonitor in Pediatrics Patients on Myelosuppresive TherapiesNo drug interventionsotherNot Availablecompleted
NCT01687400
Genomic Predictors of Decitabine Response in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromestreatment2completed
NCT04920500
Bioequivalence of Daunorubicin Cytarabine Liposomes in Naive AML PatientstreatmentNot Availableunknown_status
NCT05270200
Single Arm Study of Post-transplant Azacitidine and Chidamide for Prevention of Acute Myelogenous Leukemia Relapsetreatment1 / 2unknown_status
NCT00195000
Mylotarg and Ara-C in Untreated Patients Above 60 Years With AML and High-Risk MDStreatment2completed
NCT02785900
Vadastuximab Talirine (SGN-CD33A; 33A) Combined With Azacitidine or Decitabine in Older Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment3terminated
NCT02386800
CINC424A2X01B Rollover Protocoltreatment4recruiting
NCT04081259
LY3214996 in Patients With AML Who Are Not Candidates for Standard Therapytreatment1recruiting
NCT00143559
Stem Cell Transplantation as Immunotherapy for Hematologic MalignanciesNo drug interventionstreatment2completed
NCT00718159
Study of LY573636-sodium in Essential Thrombocythemia and Acute Myeloid Leukemiatreatment1completed
NCT01743859
Azacitidine and Lenalidomide for Relapsed and Refractory Patients With Acute Myeloid Leukemiatreatment2completed
NCT00276159
Study of Immune Response Modifier in the Treatment of Hematologic MalignanciesNo drug interventionstreatment2terminated
NCT05396859
Entrectinib in Combination With ASTX727 for the Treatment of Relapsed/Refractory TP53 Mutated Acute Myeloid Leukemiatreatment1recruiting
NCT02582359
MLN 9708 in Induction and Consolidation for Adults With AML >= 60 Years of Agetreatment1completed
NCT00678275
Chronic Graft-versus-host Disease (cGvHD) Prophylaxis With or Without ATG Prior to Stem Cell Transplantation (SCT) From HLA-identical Siblings in Patients With Acute LeukemiaNo drug interventionstreatment3completed
NCT01423175
ClAraC or FLAMSA Followed by Stem Cell Transplantation to Treat High Risk AML or Advanced MDStreatment2unknown_status
NCT05008575
Anti-CD33 CAR NK Cells in the Treatment of Relapsed/Refractory Acute Myeloid Leukemiatreatment1unknown_status
NCT04517175
Could Ki-67 be Used as a Diagnostic or Prognostic Marker in Hemato-oncological Diagnostics?No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01766375
the Effects and Safety of Idarubicin-strengthened Pretreatment Program and Conventional Busulfan Cyclophosphamide Pretreatment Program on High-risk Acute Myeloid Leukemia Patienttreatment3unknown_status
NCT05979675
Acute Myeloid Leukemia RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT03699475
Study of Haplo-HSCT + Rivogenlecleucel vs Haplo-HSCT + Post Transplant Cyclophosphamide in Patients With AML or MDStreatment2 / 3terminated
NCT03616470
Study to Determine the Efficacy of Uproleselan (GMI-1271) in Combination With Chemotherapy to Treat Relapsed/Refractory Acute Myeloid Leukemiatreatment3terminated
NCT05796570
A Pilot Study to Evaluate the Feasibility of Post-Hematopoietic Stem Cell Transplant Prophylaxis With Decitabine Combined With Filgrastim for Children and Young Adults With AML, MDS and Related Myeloid Malignanciestreatment2recruiting
NCT06034470
Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK [IMGN632]) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasmstreatment1recruiting
NCT01139970
Veliparib and Temozolomide in Treating Patients With Acute Leukemiatreatment1active_not_recruiting
NCT04083170
Cord Blood Transplant With Dilanubicel for the Treatment of HIV Positive Hematologic Cancerstreatment2terminated
NCT00151242
Study on All-Trans Retinoic Acid, Induction and Consolidation Therapy, and Pegfilgrastim After Consolidation Therapy in Younger Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment2 / 3completed
NCT00045942
PKC412 in Participants With Acute Myeloid Leukemia or With Myelodysplastic Syndrome (CPKC412A2104 Core); and PKC412 in Participants With Acute Myeloid Leukemia or With Myelodysplastic Syndrome With Either Wild Type or Mutated FMS-like Tyrosine Kinase 3 (FLT3) (CPKC412A2104E1 and CPKC412A2104E2)treatment1 / 2completed
NCT06066242
Optimizing Induction Chemotherapy Regimens for ND Elderly AML Patients Who Are Eligible for Intense ChemotherapyNo drug interventionstreatmentNot Availablerecruiting
NCT00961142
Haploidentical Stem Cell Transplantation With CD3/CD19 Depletion and Reduced Intensity Conditioning in Patients With Acute Leukemiatreatment2terminated
NCT04277442
Testing Nivolumab in Combination With Decitabine and Venetoclax in Patients With Newly Diagnosed TP53 Gene Mutated Acute Myeloid Leukemiatreatment1active_not_recruiting
NCT05448599
A Clinical Study of 6MW3211 Monotherapy or Combination Therapy for AML or MDSNo drug interventionstreatment1 / 2recruiting
NCT04065399
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutationtreatment1 / 2recruiting
NCT05005299
Venetoclax in Combination With Non-myeloablative Conditioning Allogeneic Haematopoietic Stem Cell Transplantationtreatment1recruiting
NCT00086099
Study Evaluating the Addition of Amifostine (Ethyol®) to Idarubicin and Cytosine Arabinoside in Older Patients With Acute Myeloid Leukemiatreatment1 / 2completed
NCT05984199
Donor-Derived Anti-CD33 CAR T Cell Therapy (VCAR33) in Patients With Relapsed or Refractory AML After Allogeneic Hematopoietic Cell TransplantNo drug interventionstreatment1 / 2recruiting
NCT05057299
Extramedullary Acute Myeloid Leukemia (eAML): Retrospective Single Center Cohort Study, Clinicopathological, Molecular Analysis and Survival OutcomesNo drug interventionsNot AvailableNot Availablecompleted
NCT00893399
Study of Chemotherapy in Combination With All-trans Retinoic Acid (ATRA) With or Without Gemtuzumab Ozogamicin in Patients With Acute Myeloid Leukemia (AML) and Mutant Nucleophosmin-1 (NPM1) Gene Mutationtreatment3completed
NCT03728699
Microbiota Changes in Acute Myeloid Leukemia Patients Undergoing Intensive ChemotherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT02181699
Study of KHK2823 in Patients With Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)No drug interventionstreatment1terminated
NCT05223699
Study of MGTA-117 in Patients With Adult Acute Myeloid Leukemia (AML) and Myelodysplasia-Excess Blasts (MDS-EB)No drug interventionstreatment1terminated
NCT04476199
Venetoclax and Decitabine Assessment in Patients (≥60 - <75 Years) With Newly Diagnosed AML Eligible for Allo-SCTtreatment2completed
NCT06508099
Vitamin A and D Supplementation in Allogeneic HCTtreatment2recruiting
NCT05597306
Venetoclax and Bomedemstat in Patients With Relapsed/Refractory Acute Myeloid Leukemiatreatment1recruiting
NCT01455506
PRO#0118: Decitabine Plus Mini Flu-Butreatment1completed
NCT06483906
Venetoclax and Azacitidine Combined With Homoharringtonine, Followed by Allo-HSCT for Intermediate and High-risk AML.treatment2recruiting
NCT04151706
CD34 Selected Allogeneic HCT w/ Myeloablative Conditioning Plus CD8+ Memory TCell Infusion in MDS, AL and CMLtreatment2completed
NCT05904106
Venetoclax Plus Azacitidine Versus Intensive Chemotherapy for Fit Patients With Newly Diagnosed NPM1 Mutated AMLtreatment2not_yet_recruiting
NCT01195506
Study the Novel Functions and Molecular Mechanisms of Vascular Endothelial Growth Factor-C (VEGF-C) in Acute Myeloid Leukemia (AML)No drug interventionsNot AvailableNot Availableunknown_status
NCT02927106
Beat AML Core StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT05035706
Anti-Leukemia Immune Responses After Irradiation of Extramedullary TumorsNo drug interventionstreatment0recruiting
NCT01349049
Phase 1/2 Safety and Efficacy of PLX3397 in Adults With Relapsed or Refractory Acute Myeloid Leukemia (AML)treatment1 / 2completed
NCT05945849
CD33KO-HSPC Infusion Followed by CART-33 Infusion(s) for Refractory/Relapsed AMLNo drug interventionstreatment1recruiting
NCT06477549
BeFluBu vs FluBuRux Conditioning in Haploidentical HCTtreatment2recruiting
NCT01677949
Clofarabine, Cyclophosphamide and Etoposide for Minimal Residual Disease Positive Acute Leukemiatreatment2withdrawn
NCT04242849
IDH1/2 Mutational Analysis in AML Patients: Diagnosis and Follow-upNo drug interventionsNot AvailableNot Availablecompleted
NCT03642236
Combination of BTK Inhibitor Overcomes Drug-resistance in Refractory/Relapsed FLT3 Mutant AMLtreatment2 / 3unknown_status
NCT00266136
Biology and Treatment Strategy of AML in Its Subgroups: Multicenter Randomized Trial by the German Acute Myeloid Leukemia Cooperative Group (AMLCG)treatment3completed
NCT04090736
Study to Compare Azacitidine Plus Pevonedistat Versus Azacitidine in Patients With Acute Myeloid Leukemia Not Eligible for Standard Chemotherapytreatment3unknown_status
NCT00798213
SCH 727965 in Patients With Acute Myelogenous Leukemia and Acute Lymphoblastic Leukemia (P04717AM2)(TERMINATED)treatment2terminated
NCT06535113
Decoding the Inflammasome Influence on Treatment Response in Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01370213
NK Cell Based Non-Myeloablative Transplantation in Acute Myeloid Diseasestreatment2completed
NCT04764513
Safety and Efficiency of γδ T Cell Against Hematological Malignancies After Allo-HSCTNo drug interventionstreatment1 / 2recruiting
NCT06046313
Prolonged Ultra Low-dose Decitabine Plus Venetoclax for Primary Diagnosed Elderly AMLK/MDStreatment2recruiting
NCT04625413
A Patient-centered Communication Tool (UR-GOAL) for Older Patients With Acute Myeloid Leukemia, Their Caregivers, and Their OncologistsNo drug interventionssupportive_careNot Availablecompleted
NCT00088218
Clofarabine vs Clofarabine in Plus With Low-Dose Ara-C in Previously Untreated Patients With Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndromes (MDS).diagnostic2completed
NCT02844218
Effect of Age on Treatment Decision-Making in Elderly Patients With Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT05233618
Study of Tagraxofusp for Post-Transplant Maintenance for Patients With CD 123+ AML, MF and CMML (HSCT 002)treatment1recruiting
NCT03381118
Haploidentical Lymphocytes With Nivolumab/Ara-C as Consolidation in Elderly AML Patientstreatment2terminated
NCT00513318
Pilot Study of Reduced-Intensity Umbilical Cord Blood Transplantation in Adult Patients Wtih Advanced Hematopoietic MalignanciesNo drug interventionsNot AvailableNot Availableterminated
NCT03932318
Venetoclax, Azacitidine, and Lintuzumab-Ac225 in AML Patientstreatment1 / 2withdrawn
NCT02427919
Granulocyte Colony Stimulating Factor (G-CSF) After Salvage Chemotherapy in Refractory AMLsupportive_care2 / 3unknown_status
NCT04644419
Chemotherapy-related Cognitive Impairment and Acute LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT01386619
NK DLI in Patients After Human Leukocyte Antigen (HLA)-Haploidentical Hematopoietic Stem Cell Transplantation (HSCT)treatment1 / 2completed
NCT05326919
The Patient Cohort of the National Center for Precision Medicine in LeukemiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT00862719
Sitagliptin Umbilical Cord Blood Transplant Studytreatment2completed
NCT05995041
Universal CAR-T Cells Targeting AMLNo drug interventionstreatment1recruiting
NCT04047641
Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrometreatment1 / 2recruiting
NCT01627041
Decitabine, Cytarabine, and Daunorubicin Hydrochloride in Treating Patients With Acute Myeloid Leukemiatreatment2unknown_status
NCT05029141
New Double Epigenetic Regimen in the Treatment of Relapsed or Refractory Acute Myeloid Leukemiatreatment2active_not_recruiting
NCT04817241
Testing Oral Decitabine and Cedazuridine (ASTX727) in Combination With Venetoclax for Higher-Risk Acute Myeloid Leukemia Patientstreatment1 / 2active_not_recruiting
NCT06470841
CHG Combined With Venetoclax and Azacytidine in Newly Diagnosed AMLtreatment2not_yet_recruiting
NCT05735717
MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignanciestreatment2recruiting
NCT04167917
NTX-301 in MDS/AMLNo drug interventionstreatment1recruiting
NCT03793517
Decitabine Plus mBU/CY for High Risk Acute Leukemia With MRD Pre-HSCTtreatment2 / 3recruiting
NCT06129734
Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplanttreatment1 / 2not_yet_recruiting
NCT03904134
Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (BMT CTN 1702)No drug interventionstreatmentNot Availableactive_not_recruiting
NCT05144334
A Study of BTX-1188 in Subjects With Advanced MalignanciesNo drug interventionstreatment1terminated
NCT03719534
Haplo HCT vs Haplo-cord HCT for Patients With AMLNo drug interventionstreatment3completed
NCT01686334
Efficacy Study of Dendritic Cell Vaccination in Patients With Acute Myeloid Leukemia in RemissionNo drug interventionstreatment2active_not_recruiting
NCT05829434
Magrolimab Plus Intensive Chemotherapy in Newly Diagnosed AML or HR-MDStreatment2withdrawn
NCT03128034
211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemiatreatment1 / 2suspended
NCT03245424
Ivosidenib Expanded Access Program in Relapsed/Refractory AML With an IDH1 MutationNot AvailableNot Availableapproved_for_marketing
NCT03662724
Venetoclax RegistryNot AvailableNot Availablerecruiting
NCT02508324
IPA Targeted Adoptive Immunotherapy vs Adult Haplo-identical Cell Infusion During Induction of High Risk LeukemiaNo drug interventionstreatment2terminated
NCT05541224
A Retrospective Epidemiologic Registry to Gain Insight Into the Characteristics and Prognosis of AML Patients According to the Routinely Used Genetic and Biologic MarkersNo drug interventionsNot AvailableNot Availablecompleted
NCT03483324
Trial of AB-110 in Adults With Hematologic Malignancies Undergoing Cord Blood TransplantationNo drug interventionstreatment1completed
NCT04632316
A Trial to Evaluate the Safety and Efficacy of oNKord® in Subjects With Acute Myeloid Leukemiatreatment1 / 2unknown_status
NCT03533816
Expanded/Activated Gamma Delta T-cell Infusion Following Hematopoietic Stem Cell Transplantation and Post-transplant Cyclophosphamidetreatment1recruiting
NCT03298516
A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapytreatment1completed
NCT03337516
Interest of a Therapeutic Follow-up of the Cytarabine in the Acute Myeloid Leukaemia: Is There Constitutional BiomarkersotherNot Availableunknown_status
NCT05442216
Tagraxofusp and Azaxitadine With or Without Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agentstreatment2recruiting
NCT00766116
Combination 5-azacitidine and Gemtuzumab Ozogamicin Therapy for Treatment of Relapsed Acute Myeloid Leukemia (AML)treatment1 / 2completed
NCT00089596
Infusion of Specially Treated Umbilical Cord Stem Cells After Chemoradiation Treatment for Blood CancersNo drug interventionstreatment1 / 2completed
NCT00640796
Pilot Study of Expanded, Donor Natural Killer Cell Infusions for Refractory Non-B Lineage Hematologic Malignancies and Solid Tumorstreatment1completed
NCT00037596
Study Evaluating Gemtuzumab Ozogamicin in Acute Myeloid Leukemiatreatment2completed
NCT04051996
GLAD-AML - Glasdegib (Pf-04449913) With Two Standard Decitabine Regimens for Older Patients With Poor-risk Acute Myeloid Leukemiatreatment2terminated
NCT04167696
Study in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Patients to Determine the Recommended Dose of CYAD-02treatment1recruiting
NCT06501196
A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic SyndromeNo drug interventionstreatment1recruiting
NCT03810196
CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCTNo drug interventionstreatmentNot Availablerecruiting
NCT00187096
Natural Killer (NK) Cell Transplantation for AMLtreatmentNot Availablecompleted
NCT01015196
Prospective Randomized Study Comparing One or Two High Dose Chemotherapy Regimen Followed by Autologous Stem Cell Transplantationtreatment2 / 3completed
NCT00797758
Reduction of Cord Blood Transplantation Toxicity in Patients With Acute Myeloid LeukemiaNo drug interventionstreatment2completed
NCT04095858
Efprezimod Alfa (CD24Fc, MK-7110) for the Prevention of Acute Graft Versus Host Disease (GVHD) Following Myeloablative Hematopoietic Stem Cell Transplantation (HSCT) (MK-7110-005)treatment3terminated
NCT02807558
A Biomarker-Directed Phase 2 Trial of Tamibarotene (SY-1425) in Participants With Acute Myeloid Leukemia or Myelodysplastic Syndrometreatment2completed
NCT06347458
BG1805 Injection in the Treatment of Relapsed or Refractory Acute Myeloid Leukemia in Childrentreatment1not_yet_recruiting
NCT04361058
Nivolumab for High-Risk MDS/AML Patients After Allogeneic Stem Cell Transplant With Post-Transplant Cyclophosphamidetreatment1withdrawn
NCT00565058
Combination of GTI-2040 and Cytarabine in the Treatment of Refractory and Relapsed Acute Myeloid Leukemia (AML)treatment2completed
NCT02863458
DNA Hypomethylating Agents and Lenalidomide in Elderly Patients With Myeloid Malignancies in the USNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03600558
Efficacy of FLAG Regimen for the Treatment of Patients With AMLNo drug interventionsNot AvailableNot Availableunknown_status
NCT06017258
A Study of CD371-YSNVZIL-18 CAR T Cells in People With Acute Myeloid LeukemiaNo drug interventionstreatment1recruiting
NCT01311258
Monitoring Minimal Residual Disease of Patients With Acute Myelogenous Leukemia or High Grade Myelodysplastic SyndromeNo drug interventionsNot AvailableNot Availablerecruiting
NCT03709758
Venetoclax in Combination With Intensive Induction and Consolidation Chemotherapy in Treatment Naïve AMLtreatment1recruiting
NCT05801835
A Bioequivalence Study of (Cytarabine: Daunorubicin) Liposome for InjectiontreatmentNot Availablerecruiting
NCT03127735
BAY1436032 in Patients With Mutant IDH1(mIDH1) Advanced Acute Myeloid Leukemia (AML)No drug interventionstreatment1completed
NCT02722135
A Study to Find a Safe Dose of Volasertib Given in Addition to Standard Salvage Chemotherapy in Children (Age 3 Months to Less Than 18 Years) With Acute Myeloid Leukaemia, in Whom Front-line Chemotherapy Failedtreatment1withdrawn
NCT02485535
Selinexor in Treating Patients With Intermediate- and High-Risk Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome After Transplanttreatment1completed
NCT03850535
A Study Evaluating the Safety and Efficacy of Idasanutlin in Combination With Cytarabine and Daunorubicin in Patients Newly Diagnosed With Acute Myeloid Leukemia (AML) and the Safety and Efficacy of Idasanutlin in the Maintenance of First AML Complete Remissiontreatment1 / 2terminated
NCT02084563
Study of Molecular and Genetic Abnormalities in Patients With Myeloid Neoplasmsbasic_science2completed
NCT02674763
Open-label Study of IMGN779 in Adult Patients With Relapsed/Refractory CD33-positive Acute Myeloid Leukemiatreatment1completed
NCT05968963
Electronic Health Mindfulness-based Music Therapy Intervention for Patients Undergoing Allogeneic Stem Cell TransplantationNo drug interventionssupportive_careNot Availablerecruiting
NCT06420063
Sequential CAR-T Cells Targeting CD33/CD123 in Patients With Acute Myelocytic Leukemia AMLNo drug interventionstreatment1 / 2recruiting
NCT05447663
A Study of Siremadlin Alone and in Combination With Donor Lymphocyte Infusion in Acute Myeloid Leukemia Post-allogeneic Stem Cell Transplanttreatment1 / 2terminated
NCT04265963
CD123-Targeted CAR-T Cell Therapy for Relapsed/Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1 / 2recruiting
NCT05016063
Dual CD33-CLL1-CAR-T Cells in the Treatment of Relapsed/Refractory Acute Myeloid Leukemiatreatment0unknown_status
NCT01334086
Aprepitant as Antiemetic Prophylaxis in Patients With Acute Myeloid Leukemia Undergoing Induction Chemotherapyprevention2completed
NCT02899286
Efficacy and Safety Study of Recombinant Human Arginase 1 in Patients With Relapsed or Refractory Acute Myeloid Leukemiatreatment2unknown_status
NCT01280786
Study Elesclomol Sodium in Patients With Relapsed or Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1unknown_status
NCT03055286
Clinical Study of CWP232291 in Acute Myeloid Leukemia Patientstreatment1 / 2unknown_status
NCT00859586
Mismatched Donor Lymphocyte Infusions for Relapsed Disease Following Allogeneic Stem Cell TransplantationNo drug interventionstreatmentNot Availablecompleted
NCT03315039
Study of Liposomal Annamycin for the Treatment of Subjects With Acute Myeloid Leukemia (AML)treatment1 / 2completed
NCT02646839
KIR Favorable Mismatched Haplo Transplant and KIR Polymorphism in ALL/AML/MDS Allo-HCT ChildrenNo drug interventionstreatment2enrolling_by_invitation
NCT04288739
Immunophenotyping and Xist Gene in AMLNo drug interventionsNot AvailableNot Availableunknown_status
NCT04326439
AflacLL1901 (CHOA-AML)treatment2terminated
NCT05189639
A Study To Learn About the Safety Medicine (Called Mylotarg) In People With Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT06349239
Oral Azacitidine Maintenance Post-CPX 351No drug interventionsNot AvailableNot Availablerecruiting
NCT02343939
Entospletinib Monotherapy and in Combination With Chemotherapy in Adults With Acute Myeloid Leukemia (AML)treatment1 / 2terminated
NCT05657639
CAV Regimen for R/R AMLNo drug interventionstreatment2recruiting
NCT04913922
Relatlimab With Nivolumab and 5-Azacytidine for the Treatment of AMLtreatment2recruiting
NCT02323022
Idarubicin Plus Cytarabine (IA) vs IA Plus Cladribine (IAC) as Induction Regimen to Treat Initially Diagnosed Acute Myeloid Leukemia (AML)No drug interventionstreatment3completed
NCT04613622
Pharmacokinetics of Venetoclax in Patients With Acute Myeloid LeukemiaNot AvailableNot Availablerecruiting
NCT00081822
Study of Clofarabine & Cytosine Arabinoside Therapy for Older Adults With Acute Myeloid Leukemiatreatment1completed
NCT04169022
AML Cell Immunotherapy Using Chimeric Antigen Receptor T-cellsNo drug interventionsscreeningNot Availablecompleted
NCT04351022
CD38-targeted Chimeric Antigen Receptor T Cell (CART) in Relapesd or Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1 / 2unknown_status
NCT02046122
Adoptive Transfer of Haplo-identical DLI for AML and MDStreatment1 / 2completed
NCT04272125
Safety and Efficacy of CD123-Targeted CAR-T Therapy for Relapsed/Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1 / 2recruiting
NCT02203825
Safety Study of Chimeric Antigen Receptor Modified T-cells Targeting NKG2D-LigandsNo drug interventionstreatment1completed
NCT00967525
Intraosseous Infusion of Unrelated Cord Blood GraftsNo drug interventionstreatmentNot Availableterminated
NCT02560025
Phase II Trial of Alisertib With Induction Chemotherapy in High-risk AMLtreatment2completed
NCT01075425
Belinostat and Bortezomib in Treating Patients With Relapsed or Refractory Acute Leukemia or Myelodysplastic Syndrometreatment1completed
NCT00742625
Bortezomib, Daunorubicin, and Cytarabine in Treating Older Patients With Previously Untreated Acute Myeloid Leukemiatreatment1 / 2completed
NCT01315925
Pre-hospital Risk Factors for Invasive Fungal InfectionNo drug interventionsNot AvailableNot Availableunknown_status
NCT04666025
SARS-CoV-2 Donor-Recipient Immunity TransferNo drug interventionsNot AvailableNot Availablecompleted
NCT00602225
Clofarabine, Cytarabine, and G-CSF in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemiatreatment1 / 2completed
NCT03286530
Ruxolitinib + Allogeneic Stem Cell Transplantation in AMLtreatment2recruiting
NCT02103530
Early Response Assessment of Induction Chemotherapy in Acute Myeloid Leukemia Patients Using F-18 FLT PET/CTNo drug interventionsdiagnosticNot Availablecompleted
NCT01587430
3 Anthracyclines, 2 Types of Consolidation With Different ARA-C Doses and Maintenance in Adult Acute Myeloid Leukemiatreatment4unknown_status
NCT04100330
A Study of Ficlatuzumab With HiDAC and HiDAC Alone in Adults With Relapsed or Refractory Acute Myeloid Leukemiatreatment2withdrawn
NCT05115630
Off-the-shelf NK Cells + SCT for Myeloid Malignanciestreatment1 / 2recruiting
NCT05079230
Study of Magrolimab Versus Placebo in Combination With Venetoclax and Azacitidine in Participants With Acute Myeloid Leukemiatreatment3terminated
NCT00316030
Study of Bexarotene in Patients With Acute Myeloid Leukemiatreatment1completed
NCT04771130
A Study of BGB-11417 in Participants With Myeloid Malignanciestreatment1 / 2recruiting
NCT01188330
Program of Evaluation and Geriatric Intervention on the Functional Status, Quality of the Life, and SurvivalNo drug interventionssupportive_careNot Availableunknown_status
NCT00795548
Safety Study of 5-Azacitidine and Standard Donor Lymphocyte Infusion (DLI) to Treat Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) Relapsing After Allogeneic Stem Cell Transplantationtreatment2completed
NCT04128748
Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrometreatment1 / 2recruiting
NCT03435848
Efficacy and Safety of BST-236 in Newly Diagnosed Acute Myeloid Leukemia Patients, Unfit for Standard Induction Therapytreatment2completed
NCT03066648
Study of PDR001 and/or MBG453 in Combination With Decitabine in Patients With AML or High Risk MDStreatment1completed
NCT04692948
TAA6 Cell Injection In The Treatment of Patients With Relapsed / Refractory Acute Myeloid LeukemiaNo drug interventionstreatmentNot Availableunknown_status
NCT03483948
Phase I Study of HMPL-523+Azacitidine in Elderly Patients With Acute Myeloid Leukemiatreatment1terminated
NCT02859948
A Study of SKLB1028 in Subjects With Relapsed/Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1unknown_status
NCT02848248
A Safety Study of SGN-CD123A in Patients With Acute Myeloid LeukemiaNo drug interventionstreatment1terminated
NCT01834248
DEC-205/NY-ESO-1 Fusion Protein CDX-1401and Decitabine in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemiatreatment1completed
NCT04986657
Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in AML and MDSNo drug interventionsdiagnosticNot Availablerecruiting
NCT05361057
Efficacy of Venetoclax Based Regimen in Prevention Relapse of Consecutive MRD Positive AML Patientstreatment2unknown_status
NCT02464657
Study of Idarubicin, Cytarabine, and Nivolumab in Patients With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)treatment1 / 2completed
NCT06458257
The Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation in Newly Diagnosed High-relapse-risk CEBPA Mutant Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04272957
A Study of HMPL-306 in Patients With IDH1 and/or IDH2 Mutation of Relapsed/Refractory Myeloid Leukemia/NeoplasmsNo drug interventionstreatment1unknown_status
NCT03747757
Cognitive Behavioral Therapy in Helping Patients With Acute Myeloid Leukemia or Lymphoma With Cancer-Related FatigueNo drug interventionssupportive_care2active_not_recruiting
NCT04887857
A Study to Assess Safety and Tolerability of CC-486 (ONUREG®, Oral Azacitidine) in Combination Therapy in Participants With Acute Myeloid Leukemia (AML)treatment1completed
NCT02286726
CPX-351 in Treating Patients With Newly Diagnosed, High-Risk Acute Myeloid Leukemiatreatment2completed
NCT05161026
Impact of Allo-HSCT on Bone Remodeling: Evolution of Bone Mineral Density and Architecture Measured by Bone DensitometryNo drug interventionsotherNot Availablenot_yet_recruiting
NCT03881826
Investigation of the Gut Microbiota in Patients With Acute Myeloid LeukemiaNo drug interventionsbasic_scienceNot Availablecompleted
NCT04158726
Integrating Geriatric Assessment for Older Patients Diagnosed With Acute Myelogenous LeukemiaNo drug interventionshealth_services_researchNot Availablecompleted
NCT05188326
Efficacy of 5-Aza for Post-Remission Therapy of Acute Myeloid Leukemia (AML) in Elderly Patientstreatment3completed
NCT04023526
A Study of Cusatuzumab Plus Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia Who Are Not Candidates for Intensive Chemotherapytreatment2active_not_recruiting
NCT01180426
Extension Study With Tosedostat in Relapsed/Refractory Acute Myeloid Leukemiatreatment2unknown_status
NCT00831766
Idarubicin + Cytarabine and Lenalidomide in Patients With Myelodysplastic Syndrome (MDS), Acute Myeloid Leukemia (AML)treatment1 / 2completed
NCT02099266
Use of Hyperbaric Oxygen Therapy to Improve Umbilical Cord Blood Stem Cell Homing and Subsequent EngraftmentNo drug interventionstreatmentNot Availablecompleted
NCT04062266
AZA + Venetoclax as Maintenance Therapy in Patients With AML in Remissiontreatment2recruiting
NCT06439966
Expanded Access to ABBV-787No drug interventionsNot AvailableNot Availableavailable
NCT03526666
Ascorbic Acid Levels in MDS, AML, and CMML PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT03720366
A Study of Perpetrator Drug Interactions of Enasidenib in AML Patientstreatment1completed
NCT02229266
Randomised Controlled Phase-2 Trial to Determine the Efficacy of Adoptive Immunotherapy With NK Cells in High-risk AMLtreatment2terminated
NCT00186966
Treatment of Children and Adolescents With Refractory or Relapsed Acute Myeloid Leukemiatreatment3completed
NCT04937166
A Study of Dual-SIgnaling Protein 107 (DSP107) for Patients With Hematological Malignanciestreatment1recruiting
NCT05066165
Study Investigating NTLA-5001 in Subjects With Acute Myeloid LeukemiaNo drug interventionstreatment1 / 2terminated
NCT05014165
Backtracking Leukemia-Typical Somatic Mutations in Cord BloodNo drug interventionsNot AvailableNot Availablerecruiting
NCT03233074
Constitution of a Biological Cohort Following Bone Marrow Sampling From MDS or AML Patients and Age-matched Healthy DonorsNo drug interventionsNot AvailableNot Availableterminated
NCT00861874
A Study of Decitabine in Combination With Escalating Doses of Rapamycin in Patients With Relapsed or Refractory Acute Myeloid Leukemiatreatment1completed
NCT03092674
Azacitidine With or Without Nivolumab or Midostaurin, or Decitabine and Cytarabine Alone in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrometreatment2 / 3active_not_recruiting
NCT03222674
Multi-CAR T Cell Therapy for Acute Myeloid LeukemiaNo drug interventionstreatment1 / 2unknown_status
NCT06475820
Preventing of GVHD With Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Baricitinib at Children and Young Adults With Hemoblastosistreatment2 / 3active_not_recruiting
NCT01440920
A Phase I Study of OCV-501 in Acute Myeloid Leukemia PatientsNo drug interventionstreatment1completed
NCT03484520
A Study of Venetoclax and Dinaciclib (MK7965) in Patients With Relapsed/Refractory Acute Myeloid Leukemiatreatment1terminated
NCT02059720
Haplo-SCT vs ASCT With or Without Decitabine in AML CR1No drug interventionstreatment3unknown_status
NCT00954720
Observational Study of Iron Overload in Stem Cell TransplantationNo drug interventionsNot AvailableNot Availablecompleted
NCT03096782
Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or Lymphomatreatment2completed
NCT02129582
Targeted Marrow Irradiation, Fludarabine Phosphate, and Busulfan Before Donor Progenitor Cell Transplant in Treating Patients With Hematologic Malignanciestreatment1completed
NCT02056782
A Pilot Study of Dociparstat Sodium (ODSH) in Acute Myeloid Leukemiatreatment1completed
NCT01943682
Safety Study of CPX-351 in Children With Relapsed Leukemia or LymphomaNo drug interventionstreatment1completed
NCT03560882
A Pilot Trial of Atorvastatin in Tumor Protein 53 (p53) -Mutant and p53 Wild-Type Malignanciestreatment1active_not_recruiting
NCT00079482
Study of CEP-701 (Lestaurtinib) in Patients With Acute Myeloid Leukemia (AML)treatment2completed
NCT01961882
A Phase 2 Trial to Evaluate the Efficacy and Safety of OCV-501 in Elderly Patients With Acute Myeloid LeukemiaNo drug interventionstreatment2completed
NCT04336982
A Safety and Efficacy Study of CC-90009 Combinations in Subjects With Acute Myeloid Leukemiatreatment1terminated
NCT00764231
A Study of a Home-based Exercise Intervention for Patients With Acute Myeloid Leukaemia (AML)No drug interventionstreatment2completed
NCT04906031
Sodium Stibogluconate in the MDS/AML With One of the 65 Defined p53 Mutationstreatment2unknown_status
NCT06362031
A Study to Explore Treatment Patterns, Treatment Outcomes, Healthcare Resource Utilization in Adult Participants With Acute Myeloid Leukemia (AML) Receiving Venetoclax Through Chart ReviewNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03422731
Multi-modality Imaging and Collection of Biospecimen Samples in Understanding Bone Marrow Changes in Patients With Acute Myeloid Leukemia Undergoing TBI and Chemotherapydiagnostic0recruiting
NCT06024031
NAC for Promoting Hematopoietic Recovery in Patients With Acute Myeloid Leukemia After Chemotherapytreatment2not_yet_recruiting
NCT00926731
Study to Assess the Safety and Tolerability of AZD1152 in Combination With Low Dose Cytosine Arabinoside (LDAC)treatment1completed
NCT01141673
Development of a Diagnostic Kit for FLT3-ITD in Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT03397173
TET2 Mutations in Myelodysplastic Syndromes and Acute Myeloid Leukemia With Azacitidine + Ascorbic Acidtreatment2completed
NCT00964873
A Phase 1 Study of the HSP90 Inhibitor, STA-9090 in Subjects With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Blast-phase Chronic Myelogenous Leukemiatreatment1completed
NCT03395873
Avelumab With Decitabine as First Line for AML Treatment of Patients With AML, Who Are Unfit for Intensive Chemotherapytreatment1terminated
NCT01700673
Phase II Study of Azacitidine and Sargramostim as Maintenance Treatment for Poor-Risk AML or MDStreatment2completed
NCT00866073
Study of Low-Dose Intravenous Decitabine in Patients Aged > 60 Years With Acute Myeloid Leukemiatreatment2completed
NCT01256073
A Safety and Tolerability Extension Trial Assessing Repeated Dosing of Anti-KIR (1-7F9) Human Monoclonal Antibody in Patients With Acute Myeloid Leukaemiatreatment1completed
NCT00279773
Safety, Pharmacokinetics and Pharmacodynamics of TKI258 in Subjects With Acute Myeloid Leukemiatreatment1terminated
NCT03235973
Cladribine Dose Escalation in Conditioning Regimen Prior to Allo-HSCT for Refractory Acute Leukemia and Myelodysplastic Syndromestreatment1unknown_status
NCT02034227
Safety, Tolerability Study of SG2000 in the Treatment of Advanced Chronic Lymphocytic Leukemia and Acute Myeloid Leukemiatreatment1 / 2terminated
NCT04885127
Feasibility of Telehealth Palliative Care and Digital Symptom Monitoring for Patients With Acute Myeloid LeukemiaNo drug interventionssupportive_careNot Availablerecruiting
NCT06463327
ACHIEVE2 - Safety and Preliminary Efficacy of Intravenous TCB008 in Patients With Relapse or Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)/AMLtreatment1not_yet_recruiting
NCT04107727
Trial to Compare Efficacy and Safety of Chemotherapy/Quizartinib vs Chemotherapy/Placebo in Adults FMS-like Tyrosine Kinase 3 (FLT3) Wild-type Acute Myeloid Leukemia (AML)treatment2unknown_status
NCT03379727
Study to Assess the Safety and Efficacy of Midostaurin (PKC412) in Combination With Standard Chemotherapy During Induction and Consolidation Followed by 12 Months of Maintenance Monotherapy in Patients With Newly-diagnosed FMS-like Tyrosine 3 (FLT3) Kinase Receptor-mutated Acute Myeloid Leukemia.treatment3completed
NCT01048827
Targeted, Dose-Escalation Busulfan-Etoposide as Prep Regimentreatment1completed
NCT03045627
Clinical Trial of Ara-C, Aclarubicin Combined With PEG-G-CSF for Initial Treatment of AML Patientstreatment2unknown_status
NCT03897127
Study of Standard Intensive Chemotherapy Versus Intensive Chemotherapy With CPX-351 in Adult Patients With Newly Diagnosed AML and Intermediate- or Adverse Geneticstreatment3recruiting
NCT03878927
CPX-351+GO in Subjects 55 Years Old, or Older, With AMLtreatment1terminated
NCT02949427
The Oronasal Microbiota in Pediatric Oncology PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT02109627
Ficlatuzumab With High Dose Cytarabine in Relapsed and Refractory AMLtreatment1terminated
NCT06345027
CHIMERIC ANTIGEN RECEPTOR TREATMENT TARGETING CD70 (SEVENTY)No drug interventionstreatment1not_yet_recruiting
NCT02530476
Phase I/II, Study of Selective Inhibitor of Nuclear Export (SINE) Selinexor (KPT-330) + Sorafenib in Acute Myeloid Leukemiatreatment1 / 2completed
NCT01721876
Volasertib in Combination With Low-dose Cytarabine in Patients Aged 65 Years and Above With Previously Untreated Acute Myeloid Leukaemia, Who Are Ineligible for Intensive Remission Induction Therapy (POLO-AML-2)treatment3completed
NCT00538876
Phase I Epigenetic Priming Using Decitabine With Induction Chemotherapy in AMLtreatment1completed
NCT03480360
Haploidentical Allogeneic Peripheral Blood Transplantation: Examining Checkpoint Immune Regulators' Expressiontreatment3active_not_recruiting
NCT04311060
Genetic and Molecular Characteristics of Mexican Adults With Acute Myeloid Leukemia: a Prospective Multicentric Study.No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03347994
Minnelide in Adult Patients With Relapsed or Refractory Acute Myeloid Leukemiatreatment1withdrawn
NCT05024994
A Study of E7820 in People With Bone Marrow (Myeloid) Cancerstreatment2active_not_recruiting
NCT03568994
Atovaquone (Mepron®) Combined With Conventional Chemotherapy for de Novo Acute Myeloid Leukemia (AML)treatment0active_not_recruiting
NCT06232694
Clinical Study Protocol of IAV-induced Remission Followed by Consolidation Therapy With MDCyta+Ven in ND-AMLtreatmentNot Availablerecruiting
NCT05654194
Azacitidine Combined With Venetoclax and ATRA in Newly Diagnosed AMLtreatment3recruiting
NCT03630991
Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapytreatment1recruiting
NCT03372291
Psychological Intervention Mobile App for Patients With AMLNo drug interventionssupportive_careNot Availablecompleted
NCT04477291
A Study of CG-806 in Patients With Relapsed or Refractory AML or Higher-Risk MDStreatment1active_not_recruiting
NCT02306291
Study to Determine Safety, Pharmacokinetics and Efficacy of GMI-1271 in Combination With Chemotherapy in AMLtreatment1 / 2completed
NCT05063591
Removing Transfusion Dependence as a Barrier to Hospice EnrollmentNo drug interventionssupportive_careNot Availableactive_not_recruiting
NCT02610062
A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Escalating Doses of AGS67E Given as Monotherapy in Subjects With Acute Myeloid Leukemia (AML)No drug interventionstreatment1terminated
NCT02684162
Guadecitabine and Donor Lymphocyte Infusion in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Relapsing After Allogeneic Stem Cell Transplanttreatment2active_not_recruiting
NCT01883362
Standard of Care +/- Midostaurin to Prevent Relapse Post Stem Cell Transplant in Patients With FLT3-ITD Mutated AMLprevention2completed
NCT03488862
Pilot Evaluation of a Microfluidic Assay to Detect Minimal Residual Disease and Predict Relapse in AML PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT02756962
Improving Risk Assessment of AML With a Precision Genomic Strategy to Assess Mutation Clearancetreatment2active_not_recruiting
NCT01130662
Combination of Decitabine and Midostaurin in Patients Older Than 60 With Newly Diagnosed or Relapsed Refractory Acute Myeloid Leukemiatreatment1completed
NCT06497062
Phase II Study of Sonrotoclax Combined With Chemotherapy in the Treatment of Newly Diagnosed Acute Myeloid Leukemiatreatment2not_yet_recruiting
NCT04342962
Tagraxofusp in Patients With CD123+ or With BPDCN-IPh-like Acute Myeloid Leukemiatreatment2recruiting
NCT01398462
Phase I Clinical Study of CWP232291 in Acute Myeloid Leukemia PatientsNo drug interventionstreatment1completed
NCT06220162
VAC Regimen for AML Patients Who Failed to Response to VA Regimentreatment2recruiting
NCT04953780
2157GCCC:Phase 1 of Calaspargase Pegol-mknl w/ Cytarabine and Idarubicin in Newly Dx AMLtreatment1active_not_recruiting
NCT03824080
Evaluating the Efficacy and Safety of Bemcentinib in Patients With Myelodysplastic Syndromestreatment2completed
NCT04977180
Cardioprotection in AMLNo drug interventionsprevention2recruiting
NCT04155580
A Study of ASTX660 as a Single Agent and in Combination With ASTX727 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (AML)treatment1terminated
NCT02835729
A Study of Indoximod in Combination With (7+3) Chemotherapy in Patients With Newly Diagnosed Acute Myeloid Leukemiatreatment1completed
NCT00373529
A Study of Clofarabine for Older Patients With Newly Diagnosed Acute Myelogenous Leukemia (AML) (CLASSIC II)treatment2completed
NCT03552029
Milademetan Plus Quizartinib Combination Study in FLT3-ITD Mutant Acute Myeloid Leukemia (AML)treatment1terminated
NCT02842229
A Study to Determine Final Geriatric Assessment in Haematology (GAH) Score as a Tool for Predicting Tolerance to Treatment in Elderly Patients (≥ 65 Years) With Haematologic NeoplasmsNo drug interventionsNot AvailableNot Availablecompleted
NCT01902329
A Safety Study of SGN-CD33A in AML Patientstreatment1completed
NCT02392429
FLT PET/CT in Measuring Response in Patients With Previously Untreated Acute Myeloid Leukemiadiagnostic2active_not_recruiting
NCT02348489
SGI-110 in Adults With Untreated Acute Myeloid Leukemia (AML), Not Considered Candidates for Intensive Remission Inductiontreatment3completed
NCT04464889
HA-1H TCR T Cell for Relapsed/Persistent Hematologic Malignancies After Allogeneic Stem Cell TransplantationNo drug interventionstreatment1withdrawn
NCT02096289
Safety Study of Thioridazine in Combination With Cytarabine to Treat Relapsed or Refractory Acute Myeloid Leukemiatreatment1completed
NCT06030089
Plasma Dosage of Venetoclax in the Fup of AML Patients Treated With Aza + Venbasic_scienceNot Availablerecruiting
NCT02831192
Microtransplantation in Older Patients With Acute Myeloid LeukemiaNo drug interventionstreatment2completed
NCT01819792
Respiratory Viral Infections During Acute Myeloid Leukemia (AML)Chemotherapy Related AplasiaNo drug interventionsother4completed
NCT02588092
Study of ADCT-301 in Patients With Relapsed/Refractory CD25-positive Acute Myeloid Leukemia (AML) or CD25-positive Acute Lymphoblastic Leukemia (ALL)treatment1terminated
NCT04553692
Phase 1a/1b Study of Aplitabart (IGM-8444) Alone or in Combination in Participants With Relapsed, Refractory, or Newly Diagnosed Cancerstreatment1active_not_recruiting
NCT03300492
Expanded Natural Killer Cells Following Haploidentical HSCT for AML/MDSNo drug interventionstreatment1 / 2recruiting
NCT03806192
Feasibility of Partners in Care Program for Caregivers of Patients With Acute Myeloid LeukemiaNo drug interventionssupportive_careNot Availableterminated
NCT04708444
Prognostic Value of CD318 in AML at Assiut University Hospital.No drug interventionsNot AvailableNot Availableunknown_status
NCT00469144
IV Busulfan With Allo-BMT: Study for Patients With Acute Myelogenous Leukemia and Myelodysplastic Syndrometreatment3completed
NCT03063944
STAT Inhibitor OPB-111077, Decitabine and Venetoclax in Treating Patients With Acute Myeloid Leukemia That Is Refractory, Relapsed or Newly Diagnosed and Ineligible for Intensive Chemotherapytreatment1completed
NCT06287944
225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrometreatment1not_yet_recruiting
NCT06458244
The Efficacy of Allo-HSCT in ND HR-CBF-AMLNot AvailableNot Availablenot_yet_recruiting
NCT00358644
Study of Decitabine for Treatment of Older Patients With Acute Myeloid Leukemia (AML)treatment2completed
NCT06559644
Hema-NeoTIL01 Cell Infusion Therapy in Relapsed/Refractory Acute LeukemiaNo drug interventionstreatment0not_yet_recruiting
NCT01542944
TevaGastrim for Stem Cell Mobilization Sibling Donorstreatment2completed
NCT04755244
A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)treatment1 / 2active_not_recruiting
NCT01488344
Phase I/II Trial: BIBF 1120 Added to Low-dose Cytarabine in Elderly Patients With Acute Myeloid Leukemia (AML)treatment1 / 2unknown_status
NCT04055844
Multi-Ctr PII Cmb.Modality Tx Ruxolitinib, Decitabine, and DLI for Post HSCT in AML/MDStreatment2completed
NCT05834244
A Phase Ib Trial of Azacitidine, Venetoclax and Allogeneic NK Cells for Acute Myeloid Leukemia (ADVENT-AML)treatment1recruiting
NCT05744440
Safety and Efficacy of Allogenic NK Cells in Combination With Chemotherapy in the Treatment of r/r AML After Allo-HSCTtreatment0recruiting
NCT06424340
MB-dNPM1-TCR.1 in Relapsed/Refractory AMLNo drug interventionstreatment1 / 2recruiting
NCT04254640
Efficacy and Safety of Cladribine in Combination With CAG in Newly Diagnosed Unfit Patients With AMLtreatment2unknown_status
NCT02841540
A Study of H3B-8800 (RVT-2001) in Participants With Lower Risk Myelodysplastic Syndromestreatment1terminated
NCT00908167
Sorafenib in Combination With Cytarabine and Clofarabine in Patients With Refractory or Relapsed Hematologic Malignanciestreatment1completed
NCT04087967
Study of DAC Combined With HAAG Regimen in Newly Diagnosed Younger AML Patientstreatment3unknown_status
NCT03335267
Investigator Initiated Trial of CPX-351 for Untreated Acute Myeloid Leukemiatreatment2completed
NCT04097301
Study of CAR T-cell Therapy in Acute Myeloid Leukemia and Multiple MyelomaNo drug interventionstreatment1 / 2terminated
NCT01398501
Sorafenib Maintenance Therapy for Patients With AML After Allogeneic Stem Cell Transplanttreatment1completed
NCT04128501
Venetoclax and Azacitidine for the Treatment of Acute Myeloid Leukemia in the Post-Transplant Settingtreatment2recruiting
NCT05580601
Cytokine-Induced Memory-Like Natural Killer Cells (CIML-NK) for Relapsed & Refractory Acute Myeloid Leukemia (AML)treatment1 / 2recruiting
NCT01068301
A Pediatric Study of a Plerixafor Containing Regimen In Second Allogeneic Stem Cell Transplantationtreatment1completed
NCT04742101
Phase I/II Trial of S65487 Plus Azacitidine in Acute Myeloid Leukemiatreatment1 / 2active_not_recruiting
NCT04969601
Anti-Covid-19 Vaccine in Children With Acute Leukemia and Their Siblingsprevention1 / 2completed
NCT04678401
IS-free Treg HaploHCTtreatment1recruiting
NCT01191801
Study of Vosaroxin or Placebo in Combination With Cytarabine in Patients With First Relapsed or Refractory AMLtreatment3completed
NCT05895201
High-Dose Post-Transplant Cyclophosphamide, Bortezomib, and Sitagliptin for the Prevention of GVHDtreatment1 / 2withdrawn
NCT02856204
Shotgun Sequencing in Diagnosing Febrile Neutropenia in Patients With Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT05512104
Clinical Characters and Outcome of Acute Myeloid Leukemia Patients on Correlation to CD200 and CD56 ExpressionNo drug interventionsNot AvailableNot Availableunknown_status
NCT02566304
Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignanciestreatment2active_not_recruiting
NCT04658004
NKG2D CAR-T Cell Therapy for Patients With Relapsed and/or Refractory Acute Myeloid LeukemiaNo drug interventionstreatment0not_yet_recruiting
NCT06234904
Study of IBR733 Cell Injection in Acute Myeloid LeukemiaNo drug interventionstreatment1not_yet_recruiting
NCT03150004
Efficacy and Pharmacogenomics of Cladribine Based Salvage Chemotherapy in Patients With Relapse/Refractory and Secondary Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)treatment2recruiting
NCT00986804
Decitabine Maintenance for Acute Myelogenous Leukemia (AML) and Myelodysplastic Syndrome (MDS) Post Transplanttreatment1completed
NCT05139004
90Y-DOTA-anti-CD25 Basiliximab, Fludarabine, Melphalan, and Total Marrow and Lymphoid Irradiation for the Treatment of High-Risk Acute Leukemia or Myelodysplastic Syndrometreatment1recruiting
NCT06492304
A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed/Refractory Hematologic MalignanciesNo drug interventionstreatment1 / 2recruiting
NCT01608204
Busulfan Pharmacokinetic Analysis and GST Pharmacogenetic Profile in Adults Undergoing Hematological Stem Cell TransplantationNo drug interventionsNot AvailableNot Availablecompleted
NCT05893472
A Study on the Efficacy and Safety of Venetoclax Combined With HAA Regimen in Newly Diagnosed Young AML.treatment1 / 2recruiting
NCT03012672
Higher or Lower Dose Cladribine, Cytarabine, and Mitoxantrone in Treating Medically Less Fit Patients With Newly Diagnosed Acute Myeloid Leukemia or Myeloid Neoplasmtreatment2completed
NCT03790072
Ex-vivo Expanded γδ T-lymphocytes (OmnImmune®) in Patients With Acute Myeloid Leukaemia (AML)treatment1completed
NCT03934372
Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumorstreatment1 / 2recruiting
NCT04714372
FT538 in Combination With Daratumumab in AML Acute Myeloid Leukemiatreatment1active_not_recruiting
NCT02432872
Treatment of Older Adult Acute Myeloid Leukemia Patients Aged 55 to 65 YearstreatmentNot Availableunknown_status
NCT00867672
Study of Decitabine Alone or in Combination With Valproic Acid and All-trans Retinoic Acid in Acute Myeloid Leukemiatreatment2completed
NCT05983172
Multi-omics Approach of Risk Stratification for Patients With de Novo Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT02782468
A Study of Pevonedistat in Adult East Asian Participantstreatment1completed
NCT06510868
Evaluating Myelodysplastic Syndrome Risks in NET Patients Planned for Peptide Radionuclide TherapyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02424968
CD8+ Memory T-Cells as Consolidative Therapy After Donor Non-myeloablative Hematopoietic Cell Transplant in Treating Patients With Leukemia or Lymphomatreatment2completed
NCT01643668
Busulfan/Clofarabine + Allogeneic Stem Cell Transplantationtreatment2completed
NCT03337568
Allogeneic HCT Using Uniform Conditioning Regimen Regardless of Donors (MS, MU, or HF) for AML in RemissionNo drug interventionsNot AvailableNot Availableunknown_status
NCT02502968
BL-8040 Addition to Consolidation Therapy in AML Patientstreatment2unknown_status
NCT04021368
RVU120 in Patients With Acute Myeloid Leukemia or High-risk Myelodysplastic Syndrometreatment1active_not_recruiting
NCT00909168
Induction, Consolidation and Intensification Therapy for Patients Younger Than 66 Years With Previously Untreated CD33 Positive Acute Myeloid Leukemia (AML)treatment2 / 3completed
NCT02440568
AML-02: Omacetaxine With Standard-of-Care Induction With Cytarabine & Idarubicin in Newly-Diagnosed AML Patientstreatment1 / 2terminated
NCT01565668
Open Label Study to Evaluate Safety and Efficacy of 2 Doses of Quizartinib in Patients With Relapsed or Refractory Acute Myeloid Leukemiatreatment2completed
NCT05428969
A Study to Assess Safety, Tolerability and Preliminary Efficacy of Bexmarilimab in Combination With Standard of Care in Patients With Hematological Malignanciestreatment1 / 2recruiting
NCT06073769
A Post-Marketing Surveillance Study to Assess the Safety of Oral Azacitidine Maintenance Therapy in Korean Patients With Acute Myeloid LeukemiaNot AvailableNot Availablerecruiting
NCT05456269
A Study of Bisantrene Combined With Cytarabine or With Decitabine for Adult Subjects With Extramedullary AML and MDStreatment1withdrawn
NCT05334069
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer DetectionNo drug interventionsNot AvailableNot Availablerecruiting
NCT05335369
A Patient-Centered Communication Tool (UR-GOAL) Versus Usual Care for Older Patients With Acute Myeloid Leukemia, Their Caregivers, and Their OncologistsNo drug interventionssupportive_careNot Availablerecruiting
NCT02975869
A Collaborative Palliative and Oncology Care Model for Patients With Acute Myeloid Leukemia and Myelodysplastic SyndromeNo drug interventionssupportive_careNot Availableactive_not_recruiting
NCT03941769
2018-0674 - IL-7 for T-Cell Recovery Post Haplo and CB Transplant - Phase I/IIsupportive_care1 / 2completed
NCT01463046
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrometreatment1completed
NCT00819546
RAD001 in Combination With PKC412 in Patients With Relapsed, Refractory or Poor Prognosis AML or MDStreatment1active_not_recruiting
NCT00255346
Dasatinib as Therapy for Myeloproliferative Disorders (MPDs)treatment2completed
NCT03839446
Phase II Study of the Combination of Mitoxantrone, Etoposide and Gemtuzumab Ozogamicin (MEGO) for Patients With Acute Myeloid Leukemia Refractory to Initial Standard Induction Therapytreatment2active_not_recruiting
NCT02473146
Gemtuzumab Ozogamicin+Cytarabine vs Idarubicin+Cytarabine in Elderly Patients With AML.Mylofrance 4treatment2 / 3completed
NCT02782546
Cytokine Induced Memory-like NK Cell Adoptive Therapy After Haploidentical Donor Hematopoietic Cell Transplantationtreatment2recruiting
NCT02960646
Engineered Donor Stem Cell Transplant in Treating Patients With Hematologic Malignanciestreatment1completed
NCT03493646
Evaluating in Vivo AZA Incorporation in Mononuclear Cells Following Vidaza or CC486treatment2completed
NCT03735446
Prexasertib in Combination With MEC in Relapsed/Refractory AML and High Risk MDS - a Phase I Trialtreatment1terminated
NCT03036046
Safety and Pharmacokinetics of Oral F901318 (Fluconazole and Posaconazole) IN Aml Leukaemiatreatment1 / 2withdrawn
NCT04581512
Study to Evaluate the Safety and Tolerability of EP0042treatment1 / 2recruiting
NCT01910012
PH 2 ADI-PEG 20 Acute Myeloid Leukemiatreatment2completed
NCT05312112
Real World Outcomes Using Novel Agents for AML in the UKNot AvailableNot Availablerecruiting
NCT03173612
The Efficiency of CAMS (Chinese Academy of Medical Sciences)-2016 Trial for Pediatric Acute Myeloid LeukemiatreatmentNot Availablerecruiting
NCT02842112
Higher Percentage of CD34+ CD38- Cells Detected by Multiparameter Flow Cytometry From Leukapheresis Products Predicts Unsustained Complete Remission in Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT03499912
Screening of IDH1 and IDH2 Gene Mutations in Adult Acute Myeloid Leukemia for Possible Targeted TherapyNo drug interventionsNot AvailableNot Availableunknown_status
NCT03913312
Decitabine Combined With Unrelated Cord Blood Transplantation for Elderly Patients With AMLtreatment1 / 2unknown_status
NCT03450512
Incidence of Neutropenic Enterocolitis Study in Acute Myeloid Leukemia Patients During Intensive TherapyNo drug interventionsNot AvailableNot Availablerecruiting
NCT03515512
IDH2 Inhibition Using Enasidenib as Maintenance Therapy for IDH2-mutant Myeloid Neoplasms Following Allogeneic Stem Cell Transplantationtreatment1completed
NCT02483312
A Study of (Interleukin-12) IL-12 in Patients With Acute Myelogenous Leukemia (AML)No drug interventionstreatment1recruiting
NCT00226512
To Determine the Role of Adding Campath-1H or ATG Given In-vivo in Addition to Fludarabine and Low Dose Busulfex on Outcome in Patients Treated With Reduced Intensity Conditioningtreatment3withdrawn
NCT03195010
Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced ThrombocytopeniaNo drug interventionssupportive_care2terminated
NCT06536010
Clinical Trial Protocol for the Combined Use of VAG in the Treatment of ND-AMLtreatmentNot Availablerecruiting
NCT04849910
Allogeneic Engineered Hematopoietic Stem Cell Transplant (HCT) Lacking the CD33 Protein, and Post-HCT Treatment With Mylotarg, for Patients With CD33+ AML or MDStreatment1 / 2recruiting
NCT04905810
Azacitidine or Decitabine With Venetoclax for Acute Myeloid Leukemia With Prior Hypomethylating Agent Failuretreatment2recruiting
NCT04392310
Outcomes of Acute Myeloid Leukemia PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT02400281
Study of Crenolanib Combined With Chemotherapy in FLT3-mutated Acute Myeloid Leukemia Patientstreatment1 / 2completed
NCT04267081
Study of Venetoclax in Combination With Azacytidine in AML Patients Selected Using Ex Vivo Drug Sensitivity Screeningtreatment2completed
NCT04008381
Ex-vivo Expanded γδ T Lymphocytes in Patients With Refractory/Relapsed Acute Myeloid LeukaemiaNo drug interventionstreatment1unknown_status
NCT04657081
Pharmacokinetics, Safety, and Efficacy of ASTX727 in Combination With Venetoclax in Acute Myeloid Leukemia (AML)treatment1 / 2active_not_recruiting
NCT00651781
Velcaflagida in Relapsed or Refractary Acute Myeloid Leukemiatreatment1 / 2completed
NCT00866281
A Study of the Safety and Preliminary Efficacy of Oral Midostaurin (PKC412) in Relapsed or Refractory Pediatric Leukemiatreatment1 / 2terminated
NCT06543381
Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplanttreatment1recruiting
NCT02190695
Leukemia SPORE Phase II DAC Study for R/R and Elderly Acute AML and MDStreatment2completed
NCT03603795
Study Impact on Outcome of Eltrombopag in Elderly Patients With Acute Myeloid Leukemia Receiving Induction Chemotherapytreatment2unknown_status
NCT02683395
A Study of PLX51107 in Advanced Malignanciestreatment1terminated
NCT04373395
Decitabine+Cladribine+Cytarabine+Granulocyte Colony-stimulating Factor (D-CLAG) for Relapsed or Refractory Acute Myeloid Leukemia (AML)No drug interventionstreatmentNot Availableunknown_status
NCT02159495
Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasmtreatment1active_not_recruiting
NCT01838395
Phase IIa Study Evaluating Safety and Efficacy of BL-8040 in Relapsed/Refractory AML Patientstreatment2completed
NCT02984995
Phase 2 Study of Quizartinib in Participants With Acute Myeloid Leukemia (AML) FLT3 Internal Tandem Duplication (FLT3/ITD) Mutationtreatment2completed
NCT02115295
Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemiatreatment2recruiting
NCT00224614
Randomised Prospective Comparison of the NMA Allograft and the Traditional Allograft in Acute Myeloid LeukaemiaNo drug interventionsdiagnostic3unknown_status
NCT00658814
Azacitidine and Gemtuzumab Ozogamicin in Treating Older Patients With Previously Untreated Acute Myeloid Leukemiatreatment2active_not_recruiting
NCT04296214
Pharmacoeconomics in the Application of 5-azacitidine in the Treatment of Myelodysplastic Syndromes and Acute Myeloid LeukemiaNot AvailableNot Availablewithdrawn
NCT05858814
RC1012 Injection (Allo-DNT Cells) for the Prevention of Relapse in AML Patients After Allo-HSCTNo drug interventionsprevention1 / 2recruiting
NCT05636514
Combined Evaluation of Epigenetic and Sensitising Therapy in AML and MDStreatment1recruiting
NCT02981914
Pilot Study of Pembrolizumab Treatment for Disease Relapse After Allogeneic Stem Cell Transplantationtreatment0completed
NCT03286114
Augmentation of the Graft vs. Leukemia Effect Via Checkpoint Blockade With Pembrolizumabtreatment1terminated
NCT00469014
Busulfan, Fludarabine, Clofarabine With Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemiatreatment2completed
NCT02995655
CX-01 Combined With Azacitidine in the Treatment of Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemiatreatment1completed
NCT01702155
Phase I/II Study of DFP-10917 in Patients With Acute LeukemiaNo drug interventionstreatment1 / 2completed
NCT00790855
Bendamustine in Acute Leukemia and MDStreatment1 / 2terminated
NCT02419755
Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic Malignanciestreatment2terminated
NCT03918655
MIF Involvement in AMLNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05682755
Chidamide Prevents Recurrence of High-risk AML After Allo-HSCTtreatment1 / 2recruiting
NCT03633955
Pilot Imaging Study of LeukemiaNo drug interventionsdiagnostic1recruiting
NCT03737955
Fractionated Gemtuzumab Ozogamicin in Treating Measurable Residual Disease in Patients With Acute Myeloid Leukemiatreatment2recruiting
NCT03555955
A Trial to Evaluate the Potential Impact of Renal Impairment on the Pharmacokinetics and Safety of CPX-351treatment1completed
NCT06232655
Cladribine Venetoclax in Monocytic AMLtreatment2recruiting
NCT01161550
Cladribine Based Induction Therapy With All-Trans Retinoic Acid and Midostaurin in Relapsed/Refractory AMLtreatment1completed
NCT01684150
A Phase 1, Open-Label, Dose-Escalation & Expanded Cohort, Continuous IV Infusion, Multi-center Study of the Safety, Tolerability,PK & PD of EPZ-5676 in Treatment Relapsed/Refractory Patients With Leukemias Involvingtreatment1completed
NCT02728050
Filgrastim, Cladribine, Cytarabine, and Mitoxantrone With Sorafenib in Treating Patients With Newly-Diagnosed, Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrometreatment1 / 2completed
NCT01352650
Decitabine and Plerixafor in Elderly Acute Myeloid Leukemia (AML)treatment1completed
NCT00809250
Vaccination With GM-K562 Cells in Patients With Advanced Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML) After Allogeneic Hematopoetic Stem Cell TransplantationNo drug interventionstreatment1completed
NCT04460950
Observational Study for the Evaluation of Incidence of Familial AML/MDSs in Patients With Myeloid NeoplasmsNo drug interventionsNot AvailableNot Availablerecruiting
NCT02774850
Home Away From Home - Medical OutcomesNo drug interventionsNot AvailableNot Availablecompleted
NCT02029950
Pomalidomide After Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrometreatment1completed
NCT02328950
A 5 Day Course of Fludarabine and Cytarabine Followed by Full Intensity Allogeneic Stem Cell Transplantation (FA5-Bucy) in Treating Patients With High-risk, Recurrent or Refractory Acute Leukemia and Advanced Myelodysplastic SyndromeNot AvailableNot Availableunknown_status
NCT01056523
Use of Ribavirin and Low Dose Ara-C to Treat Acute Myeloid Leukemiatreatment1 / 2completed
NCT00687323
Study of Temozolomide in Previously Untreated Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Participants With Low O6-Methylguanine Methyltransferase (MGMT) Expression (P05052)treatment2completed
NCT01701323
Expanded Cord Blood Cell Infusion Following Combination Chemotherapy in Younger Patients With Relapsed or Refractory Acute Myeloid Leukemiatreatment1terminated
NCT02928523
PreventiOn of DYSbioSis Complications With Autologous FMT in AML Patientstreatment1 / 2completed
NCT05628623
Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia (AML) Following Initial Treatmenttreatment2not_yet_recruiting
NCT02758223
Prophylactic Application of Donor-derived TCM After Allogeneic HSCTNo drug interventionstreatment1 / 2completed
NCT02920008
Phase 3 Randomized, Open-Label Study of Guadecitabine vs Treatment Choice in Previously Treated Acute Myeloid Leukemiatreatment3completed
NCT01041508
Clofarabine and Low Dose Total Body Irradiation as a Preparative Regimen for Stem Cell Transplant in Leukemia.treatment1completed
NCT05991908
Randomized Study of Conditioning of Fludarabine Combined With Single or Dual Alkylating Agents in Myeloid Malignanciestreatment3recruiting
NCT04069208
IA14 Induction in Young Acute Myeloid Leukemiatreatment2unknown_status
NCT02416908
Study of CLAG + Selinexor in Relapsed or Refractory Acute Myeloid Leukemiatreatment1 / 2completed
NCT03151408
An Efficacy and Safety Study Of Pracinostat In Combination With Azacitidine In Adults With Acute Myeloid Leukemiatreatment3terminated
NCT02024308
AML1-ETO Acute Myeloid Leukemia With Fludarabine and Cytarabine Chemotherapytreatment4unknown_status
NCT00885508
A Study of the Efficacy and Safety of Lenalidomide Combined to Escalating Doses of Chemotherapy in Intermediate-2-or High Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) With Del 5qtreatment2unknown_status
NCT02544438
Study Evaluating the Safety and Efficacy of Astarabine in Acute Myeloid Leukemia or Acute Lymphoblastic Leukemiatreatment1 / 2completed
NCT04337138
A Study Of Treatment Patterns And Clinical Outcomes In Patients Diagnosed With Acute Myeloid Leukemia Who Received Mylotarg in the Real-WorldNot AvailableNot Availablecompleted
NCT01461538
Brentuximab Vedotin in Patients With CD30-positive Nonlymphomatous Malignanciestreatment2completed
NCT06469138
A Phase 1 Study to Investigate 14C-bemcentinib Following Single Oral Administration in Healthy Male Subjectstreatment1completed
NCT01546038
A Study To Evaluate PF-04449913 With Chemotherapy In Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrometreatment2completed
NCT00931138
Treatment of Acute Myeloid Leukemia (AML) in Adults 50 to 70 Years, Study of Two Anthracyclines and the Interest of Maintenance Treatment With Interleukin 2treatment3completed
NCT02405338
DC Vaccination for Post-remission Therapy in AMLNo drug interventionstreatment1 / 2completed
NCT03932643
ONC-201 Maintenance Therapy in Acute Myeloid Leukemia and Myelodysplastic Syndrome After Stem Cell Transplanttreatment1active_not_recruiting
NCT03718143
AZD1775 in Advanced Acute Myeloid Leukemia, Myelodysplastic Syndrome and Myelofibrosistreatment2terminated
NCT00924443
A Study of Clofarabine in Older Patients With Acute Myeloid Leukemia (AML) for Whom Chemotherapy Is Not Suitabletreatment2completed
NCT04676243
Daunorubicin or Idarubicin With Cytarabine Plus Quizartinib vs Physician's Choice in Newly Diagnosed FLT3-ITD+ AMLtreatment3withdrawn
NCT06537843
Safety and Efficacy of Venetoclax, Cytarabine and Metformin (VenCM) for Relapsed-Refractory and Induction-Ineligible Acute Myeloid Leukemiatreatment2recruiting
NCT05893329
Mitoxantrone Hydrochloride Liposome Combined With Chemotherapy in Untreated de Novo Acute Myeloid LeukemiatreatmentNot Availablenot_yet_recruiting
NCT03978858
A Study of Cusatuzumab Plus Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia Who Are Not Candidates for Intensive Chemotherapytreatment2not_yet_recruiting
NCT05068401
Cryopreserved MMUD BM With PTCy for Hematologic Malignanciestreatment1not_yet_recruiting
NCT04976699
CD24Fc for the Prevention of Acute Graft Versus Host Disease (GVHD) Following Myeloablative Hematopoietic Stem Cell Transplantation (HSCT) (MK-7110-005)treatment3active_not_recruiting
NCT03826082
PRGN-3006 Adoptive Cellular Therapy Relapsed or Refractory CD33-Positive AML or High Risk MDStreatment1not_yet_recruiting
NCT00466115
A Phase II Study of MS-275, in Combination With GM-CSF Treating Relapsed and Refractory Myeloid Malignanciestreatment2unknown_status
NCT00977782
Open-label Multicenter Study of PKC412 in Pts With AML and MDS With Either Wild-type or Mutated FLT3