| DB00316 | Acetaminophen | An analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent. |
| DB00945 | Acetylsalicylic acid | A salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events. |
| DB00921 | Buprenorphine | A partial opioid agonist used for management of severe pain that is not responsive to alternative treatments. Also used for maintenance treatment of opioid addiction. |
| DB00201 | Caffeine | A stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. It is also used in to prevent and treat pulmonary complications of premature birth. |
| DB09061 | Cannabidiol | An active cannabinoid used as an adjunctive treatment for the management of seizures associated with Lennox-Gastaut syndrome or Dravet syndrome and symptomatic relief of moderate to severe neuropathic pain or other painful conditions, like cancer. |
| DB01401 | Choline magnesium trisalicylate | Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults. |
| DB00318 | Codeine | An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. |
| DB00861 | Diflunisal | An NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis. |
| DB01551 | Dihydrocodeine | An opioid analgesic agent used for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. |
| DB01628 | Etoricoxib | A selective COX-2 inhibitor used to relieve moderate post-surgical dental pain as a short-term treatment and inflammatory and painful symptoms of various forms of arthritis. |
| DB00573 | Fenoprofen | An anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis. |
| DB00956 | Hydrocodone | An opioid agonist used as an analgesic and antitussive agent. |
| DB01050 | Ibuprofen | An NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation. |
| DB01009 | Ketoprofen | An NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain. |
| DB00854 | Levorphanol | An opioid analgesic used to treat moderate to severe pain. |
| DB00939 | Meclofenamic acid | An NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis. |
| DB00784 | Mefenamic acid | An NSAID used to treat mild to moderate pain for no more than a week, and primary dysmenorrhea. |
| DB01028 | Methoxyflurane | For use in the induction and maintenance of general anesthesia |
| DB00844 | Nalbuphine | An opioid agonist-antagonist used to treat pain, for pre and postoperative analgesia, and for analgesia in labor and delivery. |
| DB01183 | Naloxone | An opioid receptor antagonist used to rapidly reverse an opioid overdose. Also included in some drug formulations as an abuse deterrent to prevent injection. |
| DB01173 | Orphenadrine | A muscarinic antagonist used as an adjunct for the symptomatic relief of musculoskeletal pain and discomfort. |
| DB01192 | Oxymorphone | An opioid analgesic used in the management of moderate-to-severe pain and for analgesic therapies. |
| DB00652 | Pentazocine | An analgesic used to treat moderate to severe pain. |
| DB00193 | Tramadol | A centrally-acting opioid agonist and SNRI (serotonin/norepinephrine reuptake inhibitor) used for the management of moderate to severe pain in adults. |