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Displaying results 91 - 100 of 138756 in total
  1. Pathway

    Metabolism and Physiological Effects of N-Acetyl-3-Methylhistidine

    smpdb.ca/view/SMP0126795
    Metabolic

    N-Acetyl-3-methylhistidine, an N-acetyl-L-amino acid, belongs to the class of organic compounds known as histidine and derivatives. … Higher circulating levels of five of these N-acetylated amino acids, namely, N-δ-acetylornithine, N-acetyl-1-methylhistidine, N-acetyl-3-methylhistidine, N-acetylhistidine, and N2,N5-diacetylornithine,

    Drugs: Histidine · Ademetionine
  2. Pathway

    Metabolism and Physiological Effects of N-alpha-Acetyl-L-arginine

    smpdb.ca/view/SMP0125530
    Metabolic

    Glutamic acid is carboxylated into 1-Pyrroline-5-carboxylic acid by the enzyme Delta-1-pyrroline-5-carboxylate synthase. 1-Pyrroline-5-carboxylic acid with glutaric acid synthesize Oxoglutaric acid and … Arginnosuccinate is synthesized from citrulline and aspartic acid by the enzyme argininosuccinate synthase. That is catalyzed by argininosuccinate lyase to produce arginine and fumaric acid.

    Drugs: Pyridoxal phosphate · Arginine · Aspartic acid · Ornithine · L-Glutamine · Adenosine phosphate +10 more
    Enzymes: Neutral amino acid transporter A, Low affinity cationic amino acid transporter 2
  3. Pathway

    Ziconotide NMDA and Substance P Receptor Pain Inhibition Action Pathway

    smpdb.ca/view/SMP0126347
    Drug action

    Therefore substance P, CGRP, and glutamate are not released into the synapse and cannot activate the substance P receptors, CGRP receptors, or the N-Methyl-D-aspartic acid receptors on the post-synaptic … such as intrathecal morphine and systemic analgesics.

    Drugs: Glutamic acid · Calcium · Sar9, Met (O2)11-Substance P · Ziconotide
  4. Pathway

    Sulfate/Sulfite Metabolism

    smpdb.ca/view/SMP0000041
    Metabolic

    This pathway illustrates the conversion of sulfite to sulfate (via sulfate oxidase) and subsequent generation of adenylylsulfate (APS) via 3'-phosphoadenosine 5'-phosphosulfate synthase 2. … Recall, that the sulfite ion is in fact the conjugate base of sulfurous acid. Moreover, this ion is found naturally in one of the worlds most popular beverages, wines.

    Drugs: ATP · Estrone · Magnesium cation · Mesoheme · Propyl alcohol · Phenol +2 more
    Enzymes: Sulfite oxidase, mitochondrial
  5. Pathway

    Icosapent Prostaglandin G/H synthase 1 and 2 anti-inflammatory Action Pathway

    smpdb.ca/view/SMP0126557
    Drug action

    Icosapent is an important polyunsaturated fatty acid (eicosapentaenoic acid (EPA)). It is mostly found in fish oils. … This molecule also inhibits the arachidonic acid conversion into the thromboxane-2 and prostaglandin-2 families because it inhibits the prostaglandin G/H synthase 1 and 2 (COX-1 and COX-2).

    Drugs: Glutathione · Icosapent · Dinoprostone · Calcium · Mesoheme · Prostaglandin G2 +1 more
  6. Pathway

    Fish oil Prostaglandin G/H synthase 1 and 2 anti-inflammatory Action Pathway

    smpdb.ca/view/SMP0126563
    Drug action

    Fish oil is made of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). … These are responsible for the conversion of arachidonic acid (an omega-6 fatty acid) into prostaglandins and thromboxanes, which are important mediators of inflammation and pain.

    Drugs: Glutathione · Icosapent · Dinoprostone · Calcium · Mesoheme · Prostaglandin G2 +1 more
  7. Pathway

    Aluminum acetate Drug Metabolism

    smpdb.ca/view/SMP0130582
    Metabolic

    Aluminum acetate passes through the liver and is then excreted from the body mainly through the kidney. … Aluminum acetate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Aluminum acetate
  8. Pathway

    Aluminum subacetate Drug Metabolism

    smpdb.ca/view/SMP0130623
    Metabolic

    Aluminum subacetate passes through the liver and is then excreted from the body mainly through the kidney. … Aluminum subacetate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Aluminum subacetate
  9. Pathway

    Aluminum zirconium octachlorohydrex gly Drug Metabolism

    smpdb.ca/view/SMP0130523
    Metabolic

    Aluminum zirconium octachlorohydrex gly passes through the liver and is then excreted from the body mainly through the kidney. … Aluminum zirconium octachlorohydrex gly is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Aluminum zirconium octachlorohydrex gly
  10. Pathway

    Ferrous glycine sulfate Drug Metabolism

    smpdb.ca/view/SMP0130551
    Metabolic

    Ferrous glycine sulfate passes through the liver and is then excreted from the body mainly through the kidney. … Ferrous glycine sulfate is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Ferrous glycine sulfate