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Displaying results 91 - 100 of 13237 in total
  1. Drug

    Midazolam

    go.drugbank.com/drugs/DB00683
    ApprovedIllicitInvestigational

    [A257153] Midazolam is considered a schedule IV drug in the United States due to the low potential for abuse and low risk of dependence.[L5074] … [A173842] It belongs to a class of drugs called _benzodiazepines_. This drug is unique from others in this class due to its rapid onset of effects and short duration of action.

    Products: N/a, Midazolam in Sodium Chloride
  2. Drug

    Triptorelin

    go.drugbank.com/drugs/DB06825
    ApprovedInvestigationalVet approved

    After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. … Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH).

    Products: Triptofem 0,1 mg/ml Injektionslösung in einer Fertigspritze, Decapeptyl Depot - Retardmikrokapseln und Suspensionsmittel in Einmalspritzen
  3. Drug

    Insulin human

    go.drugbank.com/drugs/DB00030
    ApprovedInvestigational

    If left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening … Human insulin is also available in an inhalable form, intended to be used as a bolus meal-time insulin.

    Mixtures: Humulin 10/90 Inj, Humulin 10/90 InjCategories: Drugs Used in Diabetes
  4. Pathway

    The Oncogenic Action of D-2-Hydroxyglutarate in Hydroxyglutaric aciduria

    smpdb.ca/view/SMP0002359
    Disease

    This results in modulations of HIF-mediated hypoxia responses and alterations in gene expression through global epigenetic remodelling that may contribute to malignant transformation. 2-Hydroxyglutarate … A mutation in IDH causes high concentrations of D-2-Hydroxyglutaric acid. D-2-hydroxyglutarate is a competitive inhibitor of 2OG-dependent dioxygenases resulting in genetic changes and malignancies.

    Drugs: Pyruvic acid · Biotin · L-Glutamine · Succinic acid · Glutamic acid · NADH +6 more
  5. Drug

    Magnesium sulfate

    go.drugbank.com/drugs/DB00653
    ApprovedInvestigationalVet approved

    A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. … It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions.

    Synonyms: magnesium(II) sulfateMixtures: Magnesium Sulfate In 5% Dextrose Inj(20mg/ml), Multiple Electrolyte Additive Inj
  6. Drug

    Rabies immune globulin, human

    go.drugbank.com/drugs/DB11603
    Approved

    IMOGAM Rabies Pasteurized is indicated for post-exposure prophylaxis in persons suspected of exposure to rabies, who have not previously received a complete immunization regimen with a cell culture produced … Persons previously vaccinated with other types of rabies vaccines in whom adequate antibody levels have not been demonstrated should receive full post-exposure prophylaxis with RIG and a cell culture-produced

    Products: Rabipur Pulver und Lösungsmittel zur Herstellung einer Injektionslösung in einer Fertigspritze, EQUIRAB 1000 IU/5ML IM/SC ÇÖZELTI IÇEREN FLAKON, 1 ADET
  7. Drug

    Carteolol

    go.drugbank.com/drugs/DB00521
    Approved

    A beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.

    Products: ARTEOPTIC LA, CARTEOL LP %1 UZUN ETKILI GOZ DAMLASI, 3 ML
  8. Pathway

    Homocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type

    smpdb.ca/view/SMP0000570
    Disease

    Methionine synthase deficiency is characterized by an increase in homocysteine levels in the body and excreted in the urine, as well as decreased levels of methionine in the blood. … It is caused by a mutation in the MTR gene which encodes the enzyme methionine synthase.

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 more
  9. Drug

    Metoprolol

    go.drugbank.com/drugs/DB00264
    ApprovedInvestigational

    Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. … [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US.

    Mixtures: METOPROLOLSUC 1A PL95/12.5, METOPROLOLSUC 1A PL95/12.5Synonyms: 1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol
  10. Drug

    Filgrastim

    go.drugbank.com/drugs/DB00099
    ApprovedInvestigational

    [L40719] It has a number of therapeutic uses, including the management and prevention of infections and febrile neutropenia in patients receiving myelosuppressive chemotherapy or radiation therapy. … It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_.

    Products: ZARZIO SOLUTION FOR INJECTION/INFUSION IN A PREFILLED SYRINGE 30MU/0.5ML, ACCOFIL 30 SOLUTION FOR INJECTION OR INFUSION IN A PRE-FILLED SYRINGE 30 MU/0.5 ML