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Salicylic acid
go.drugbank.com/drugs/DB00936ApprovedInvestigationalVet approvedIts salts, the salicylates, are used as analgesics. … A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions.
Synonyms: 2-Carboxyphenol, O-carboxyphenolMixtures: P&s Plus, DERMOTIL-S® UNGUENTOEphedrine
go.drugbank.com/drugs/DB01364ApprovedInvestigational[A193698] Ephedrine acts as both a direct and indirect sympathomimetic. … [A193701,A193704,L12975] Ephedrine was granted a type 7 FDA Approval on 29 April 2016.[L12975]
Mixtures: WICK MediNait Erkältungssirup für die Nacht, SP-BROM ELIXIRSynonyms: (1R,2S)-1-Phenyl-1-hydroxy-2-methylaminopropane, L-erythro-2-(Methylamino)-1-phenylpropan-1-olMercaptopurine Metabolism Pathway
smpdb.ca/view/SMP0000609Drug metabolismMercaptopurine is a purine antimetabolite prodrug that exerts cytotoxic effects via three mechanisms: via incorporation of thiodeoxyguanosine triphosphate into DNA and thioguanosine triphosphate into RNA, inhibition of de novo synthesis ...
Enzymes: Thiopurine S-methyltransferaseMesoridazine Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126523Drug actionMesoridazine, the besylate salt of a metabolite of thioridazine, is a phenothiazine tranquilizer and a first generation typical antipsychotic. Based upon animal studies, mesoridazine, as with other phenothiazines, acts indirectly on reti...
Enzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortQuetiapine Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126827Drug actionQuetiapine is used in the symptomatic treatment of schizophrenia. In addition, it may be used for the management of acute manic or mixed episodes in patients with bipolar I disorder, as a monotherapy or combined with other drugs. It may ...
Enzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortAgalsidase beta
go.drugbank.com/drugs/DB00103ApprovedInvestigational[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009. … Agalsidase beta is a recombinant human α-galactosidase A similar to [agalsidase alfa].
Products: ฟาบราไซม์ (5 มก.), REPLAGAL 1 MG/ML IV İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADETIndacaterol
go.drugbank.com/drugs/DB05039ApprovedInvestigationalIt was approved by the European Medicines Agency (EMA) on 30 November 2009 and by the FDA on 1 July 2011. It is marketed in Europe as Onbrez and in America as Arcapta Neohaler. … Indacaterol is provided as its maleate salt form. Indacaterol is also a chiral molecule but only the pure R-enantiomer is dispensed.
Mixtures: ATECTURA®BREEZHALER®150/80 MCG POLVO PARA INHALACIÓN CÁPSULA DURA, ULTIBRO- BREEZHALER®Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesOxycodone
go.drugbank.com/drugs/DB00497ApprovedIllicitInvestigationalOxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. … [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics
Mixtures: DEPALGOS® 5 MG /325 MG, SENIDOL ®Categories: oxycodone and naltrexone, Cytochrome P-450 SubstratesVilazodone mechanism of Action Action Pathway
smpdb.ca/view/SMP0126404Drug actionVilazodone selectively inhibits serotonin reuptake in the central nervous system as well as acting as a partial agonist of 5HT-1A receptors. The exact mechanism for how these effects translate to its antidepressant effects are not known ...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Agalsidase alfa
go.drugbank.com/drugs/DB15874ApprovedInvestigational[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009. … Agalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta].
Synonyms: alpha-D-galactosidase, alpha-galactosidase AProducts: REPLAGAL CONCENTRATE FOR SOLUTION FOR INFUSION 1 MG/ML