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Displaying results 1011 - 1020 of 10000 in total
  1. Drug

    Pioglitazone

    go.drugbank.com/drugs/DB01132
    ApprovedInvestigational

    [L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert _in vivo_ with little consequence … [A19757] PPARs are ligand-activated transcription factors that are involved in the expression of more than 100 genes and affect numerous metabolic processes, most notably lipid and glucose homeostasis.

    Mixtures: PIO-ALA 15/600 MG FILM KAPLI TABLET ,30 ADET, PIO-ALA 15/600 MG FILM KAPLI TABLET ,90 ADETCategories: Drugs Used in Diabetes
  2. Indication

    Human Influenza

    go.drugbank.com/conditions/DBCOND0043089
    Drugs: Acetaminophen · Acetylsalicylic acid · Ascorbic acid · Baloxavir marboxil · Brompheniramine · Caffeine +29 more
    Synonyms: Influenza in Human, Influenza in Humans
  3. Indication

    Erythropoietin Resistant Anemia (EPO Resistant Anemia)

    go.drugbank.com/conditions/DBCOND0161719
    Drugs: Vadadustat
    Synonyms: Anemia in Chronic Kidney Diseases, Anaemia in Chronic Kidney Disease
  4. Target

    Diadenosine hexaphosphate hydrolase

    go.drugbank.com/bio_entities/BE0002822
    TargetThermus thermophilus

    Specifically hydrolyzes (di)adenosine polyphosphates but not ATP or diadenosine triphosphate, generating ATP as the product.

    Synonyms: ATP-generating (di)nucleotide polyphosphate hydrolase
  5. Target

    Type II iodothyronine deiodinase

    go.drugbank.com/bio_entities/BE0009855
    EnzymeTargetHumans

    Plays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination (PubMed:12586771, PubMed:11108274, PubMed:10403186, PubMed:18821722

    Synonyms: Type 2 DI
  6. Drug

    Azelastine

    go.drugbank.com/drugs/DB00972
    ApprovedInvestigational

    [L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first granted FDA approval in 1996. … [L8240,L8270] Azelastine is also available in combination with fluticasone propionate as a nasal spray marketed under the trade name Dymista™, which is indicated for the symptomatic treatment of seasonal

    Mixtures: DYMISTA D, N-S-4Products: Azela-Vision sine 0,5 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis, Vividrin Azelastin EDO 0,5 mg/ml Augentropfen, Lösung im Einzeldosisbehältnis
  7. Drug

    Testosterone undecanoate

    go.drugbank.com/drugs/DB13946
    ApprovedInvestigational

    [L35970] It was developed via fatty acid esterification of testosterone in order to achieve orally administer testosterone. … Testosterone undecanoate is the ester prodrug of [testosterone] and has a mid-chain fatty acid at the carbon 17β position.

    Products: NEBIDO 250 MG/ML IM ENJEKSIYONLUK COZELTI ICEREN FLAKON, 1 ADET
  8. Indication

    Decreased appetite

    go.drugbank.com/conditions/DBCOND0012116
    Drugs: Bromopride · Rhubarb
    Synonyms: Decrease in appetite (finding)
  9. Indication

    Relapsed Acute Lymphoblastic Leukemia (ALL)

    go.drugbank.com/conditions/DBCOND0069491
    Drugs: Clofarabine · Vincristine
    Synonyms: Acute Lymphoblastic Leukemia, in Relapse
  10. Drug

    Hypochlorous acid

    go.drugbank.com/drugs/DB14135
    Investigational

    An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Chlor(I)-säure