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C-X-C chemokine receptor type 2
go.drugbank.com/bio_entities/BE0010516TargetHumansReceptor for interleukin-8 which is a powerful neutrophil chemotactic factor (PubMed:1891716). Binding of IL-8 to the receptor causes activation of neutrophils.
Polypeptides: C-X-C chemokine receptor type 2Synonyms: GRO/MGSA receptor, IL-8 receptor type 2Tumor necrosis factor receptor superfamily member 16
go.drugbank.com/bio_entities/BE0010540TargetHumansLow affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. … Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF (PubMed:24908487).
Polypeptides: Tumor necrosis factor receptor superfamily member 16Synonyms: NGF receptor, Low affinity neurotrophin receptor p75NTRAntiviral innate immune response receptor RIG-I
go.drugbank.com/bio_entities/BE0012418TargetHumansInnate immune receptor that senses cytoplasmic viral nucleic acids and activates a downstream signaling cascade leading to the production of type I interferons and pro-inflammatory cytokines (PubMed:15208624
Polypeptides: Antiviral innate immune response receptor RIG-ISynonyms: RIG-I-like receptor 1Tumor necrosis factor receptor superfamily member 13C
go.drugbank.com/bio_entities/BE0018598TargetHumansB-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response
Polypeptides: Tumor necrosis factor receptor superfamily member 13CSynonyms: BAFF receptor, BLyS receptor 3Tumor necrosis factor receptor superfamily member 12A
go.drugbank.com/bio_entities/BE0020009TargetHumansReceptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins
Polypeptides: Tumor necrosis factor receptor superfamily member 12ASynonyms: Tweak-receptorAcetylcholine receptor subunit alpha-type acr-16
go.drugbank.com/bio_entities/BE0027703TargetCaenorhabditis elegansA subunit of the levamisole-insensitive nicotinic receptor.
Polypeptides: Acetylcholine receptor subunit alpha-type acr-16Ipecac
go.drugbank.com/drugs/DB13293ApprovedWithdrawn[L1113] The FDA does not have currently any approved product containing ipecac, however, ipecac as an ingredient is accepted to be sold over the counter in packages of 1 fluid ounce (30 ml) for the emergency
Cyproheptadine
go.drugbank.com/drugs/DB00434ApprovedInvestigationalCyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors. It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation and its off-label use in ...
Categories: Serotonin Receptor Antagonists, Serotonin 5-HT2 Receptor AntagonistsObesity
go.drugbank.com/conditions/DBCOND0015947Drugs: Amphetamine · Benzphetamine · Bupropion · Fluoxetine · Lecithin, soybean · Lorcaserin +6 moreIslatravir
go.drugbank.com/drugs/DB15653ApprovedInvestigationalIslatravir is a first-in-class, highly potent nucleoside reverse transcriptase translocation inhibitor (NRTTI) used in combination therapy for the treatment of HIV-1 infection. Chemically, it is a deoxyadenosine analogue distinguished by...