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High affinity immunoglobulin gamma Fc receptor I
go.drugbank.com/bio_entities/BE0000710TargetCarrierHumansHigh affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.
Polypeptides: High affinity immunoglobulin gamma Fc receptor ISynonyms: IgG Fc receptor IGamma-aminobutyric acid receptor subunit alpha-6
go.drugbank.com/bio_entities/BE0000764TargetHumansAlpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:8632757). GABA-gated chloride channels, also named GABA(A) receptors (G...
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-6Synonyms: GABA(A) receptor subunit alpha-6Tyrosine-protein phosphatase non-receptor type 4
go.drugbank.com/bio_entities/BE0000980TargetHumansPhosphatase that plays a role in immunity, learning, synaptic plasticity or cell homeostasis (PubMed:25825441, PubMed:27246854). Regulates neuronal cell homeostasis by protecting neurons against apoptosis (PubMed:20086240). Negatively re...
Polypeptides: Tyrosine-protein phosphatase non-receptor type 4Tumor necrosis factor receptor superfamily member 1A
go.drugbank.com/bio_entities/BE0001139TargetHumansReceptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor.
Polypeptides: Tumor necrosis factor receptor superfamily member 1ASynonyms: Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type ITriggering receptor expressed on myeloid cells 1
go.drugbank.com/bio_entities/BE0001288TargetHumansBy also promoting the amplification of inflammatory signals that are initially triggered by Toll-like receptor (TLR) and NOD-like receptor engagement, plays a major role in the pathophysiology of acute … Cell surface receptor that plays important roles in innate and adaptive immunity by amplifying inflammatory responses (PubMed:10799849, PubMed:21393102).
Polypeptides: Triggering receptor expressed on myeloid cells 1Synonyms: Triggering receptor expressed on monocytes 1Gamma-aminobutyric acid receptor subunit beta-1
go.drugbank.com/bio_entities/BE0002344TargetHumansBeta subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:10449790, PubMed:16412217, PubMed:26950270). GABA-gated chloride channel...
Polypeptides: Gamma-aminobutyric acid receptor subunit beta-1Synonyms: GABA(A) receptor subunit beta-1Gamma-aminobutyric acid receptor subunit beta-2
go.drugbank.com/bio_entities/BE0002346TargetHumansBeta subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:19763268, PubMed:27789573, PubMed:29950725, PubMed:8264558). GABA-gated ...
Polypeptides: Gamma-aminobutyric acid receptor subunit beta-2Synonyms: GABA(A) receptor subunit beta-2Tumor necrosis factor receptor superfamily member 11A
go.drugbank.com/bio_entities/BE0003461TargetHumansReceptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed:9878548). … Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2 (By similarity).
Polypeptides: Tumor necrosis factor receptor superfamily member 11ASynonyms: Receptor activator of NF-KB, Osteoclast differentiation factor receptorC-X-C chemokine receptor type 1
go.drugbank.com/bio_entities/BE0003552TargetHumansReceptor to interleukin-8, which is a powerful neutrophils chemotactic factor (PubMed:1840701). Binding of IL-8 to the receptor causes activation of neutrophils. … This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:8662698)
Polypeptides: C-X-C chemokine receptor type 1Synonyms: IL-8 receptor type 1, High affinity interleukin-8 receptor AGamma-aminobutyric acid receptor subunit gamma-2
go.drugbank.com/bio_entities/BE0003592TargetHumansGABAARs function also as histamine receptor where histamine binds at the interface of two neighboring beta subunits and potentiates GABA response in a gamma-2 subunit-controlled manner (By similarity)
Polypeptides: Gamma-aminobutyric acid receptor subunit gamma-2Synonyms: GABA(A) receptor subunit gamma-2