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Neuronal acetylcholine receptor subunit alpha-7
go.drugbank.com/bio_entities/BE0002341TargetHumansIn T cells, activation induces metabotropic signaling that results in an increase of intracellular Ca2+ concentrations, independent of ionotropic receptor functions (PubMed:17709503).
Polypeptides: Neuronal acetylcholine receptor subunit alpha-7Synonyms: Nicotinic acetylcholine receptor subunit alpha-7Growth hormone secretagogue receptor type 1
go.drugbank.com/bio_entities/BE0003383TargetHumansG protein-coupled receptor specific to ghrelin, an appetite-regulating peptide hormone commonly found in stomach (PubMed:35027551, PubMed:39833471).
Polypeptides: Growth hormone secretagogue receptor type 1Synonyms: Ghrelin receptor, GH-releasing peptide receptorC-C chemokine receptor type 2
go.drugbank.com/bio_entities/BE0003387TargetHumansAlso acts as a receptor for the beta-defensin DEFB106A/DEFB106B (PubMed:23938203). … Key functional receptor for CCL2 but can also bind CCL7, and CCL12 (PubMed:23408426, PubMed:38157855, PubMed:8048929, PubMed:8146186). Also transduces signaling mediated by CCL13 (PubMed:38157855).
Polypeptides: C-C chemokine receptor type 2Synonyms: Monocyte chemoattractant protein 1 receptorC-C chemokine receptor type 1
go.drugbank.com/bio_entities/BE0003509TargetHumansChemokine receptor that plays a crucial role in regulating immune cell migration, inflammation, and immune responses (PubMed:14991608).
Polypeptides: C-C chemokine receptor type 1Synonyms: LD78 receptor, Macrophage inflammatory protein 1-alpha receptorReceptor-type tyrosine-protein phosphatase S
go.drugbank.com/bio_entities/BE0003567TargetHumansCell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycan (PubMed:21454754).
Polypeptides: Receptor-type tyrosine-protein phosphatase SSynonyms: Receptor-type tyrosine-protein phosphatase sigmaReceptor-type tyrosine-protein phosphatase epsilon
go.drugbank.com/bio_entities/BE0003568TargetHumansIsoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity)
Polypeptides: Receptor-type tyrosine-protein phosphatase epsilonNeuronal acetylcholine receptor subunit beta-4
go.drugbank.com/bio_entities/BE0003584TargetHumansCHRNA3:CHRNB4 being predominant in neurons of the autonomic ganglia, it is known as ganglionic nicotinic receptor (PubMed:31488329).
Polypeptides: Neuronal acetylcholine receptor subunit beta-4Function: acetylcholine receptor activityNeuronal acetylcholine receptor subunit alpha-6
go.drugbank.com/bio_entities/BE0003587TargetHumansComponent of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collecti...
Polypeptides: Neuronal acetylcholine receptor subunit alpha-6Function: acetylcholine receptor activityNeuronal acetylcholine receptor subunit beta-3
go.drugbank.com/bio_entities/BE0003588TargetHumansModulates receptor assembly and increases receptor sensitivity to nicotine when associated with CHRNB2, CHRNA4 and/or CHRNA6 as well as CHRNA3 and CHRNB4 (PubMed:11118490, PubMed:16835356).
Polypeptides: Neuronal acetylcholine receptor subunit beta-3Gamma-aminobutyric acid receptor subunit epsilon
go.drugbank.com/bio_entities/BE0003595TargetHumansEpsilon subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:16412217, PubMed:9882711). GABA-gated chloride channels, also named G...
Polypeptides: Gamma-aminobutyric acid receptor subunit epsilonSynonyms: GABA(A) receptor subunit epsilon