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Maltose-6'-phosphate glucosidase
go.drugbank.com/bio_entities/BE0001309TargetBacillus subtilis (strain 168)Is also able to significantly catalyze the hydrolysis of both 6-phospho-alpha- and 6-phospho-beta-glucosides containing activated leaving groups such as p-nitrophenol and does so with retention and inversion … Hydrolyzes maltose-6'-phosphate and trehalose-6'-phosphate.
Synonyms: 6-phosphoryl-O-alpha-D-glucopyranosyl:phosphoglucohydrolaseMitochondrial peptide methionine sulfoxide reductase
go.drugbank.com/bio_entities/BE0000170TargetEnzymeHumansPlays a crucial role in repairing oxidized methionine residues in key lens proteins, such as alpha-crystallin (CRYAA/CRYAB) and cytochrome c (CYCS), thereby restoring their function and maintaining lens … Has an important function as a repair enzyme for proteins that have been inactivated by oxidation (PubMed:10452521, PubMed:12039877).
Synonyms: Peptide Met(O) reductasePeptide methionine sulfoxide reductase MsrA
go.drugbank.com/bio_entities/BE0001618TargetShigella flexneriHas an important function as a repair enzyme for proteins that have been inactivated by oxidation.
Synonyms: Peptide Met(O) reductaseArylamine N-acetyltransferase 2
go.drugbank.com/bio_entities/BE0003607EnzymeHumansCatalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates (PubMed:12222688, PubMed:7915226). … Participates in the detoxification of a plethora of hydrazine and arylamine drugs, and is able to bioactivate several known carcinogens
Synonyms: N-hydroxyarylamine O-acetyltransferase1-acyl-sn-glycerol-3-phosphate acyltransferase beta
go.drugbank.com/bio_entities/BE0011578TargetHumansConverts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol
Synonyms: 1-acylglycerol-3-phosphate O-acyltransferase 2Function: 1-acylglycerol-3-phosphate O-acyltransferase activityImmunoglobulin J chain
go.drugbank.com/bio_entities/BE0009083TargetHumansIn the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces dimers and/or larger polymers.
Synonyms: Joining chain of multimeric IgA and IgMLysocardiolipin acyltransferase 1
go.drugbank.com/bio_entities/BE0015711EnzymeHumansRecognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors (By similarity). … Required for establishment of the hematopoietic and endothelial lineages (By similarity)
Synonyms: 1-acylglycerol-3-phosphate O-acyltransferase 8Function: 1-acylglycerol-3-phosphate O-acyltransferase activityProlyl 3-hydroxylase OGFOD1
go.drugbank.com/bio_entities/BE0002210TargetHumansProlyl 3-hydroxylase that catalyzes 3-hydroxylation of 'Pro-62' of small ribosomal subunit uS12 (RPS23), thereby regulating protein translation termination efficiency. Involved in stress granule formation
Synonyms: Termination and polyadenylation 1 homolog, 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1Complement C5
go.drugbank.com/bio_entities/BE0000855TargetHumansPrecursor of the C5a anaphylatoxin and complement C5b components of the complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that … Activated downstream of classical, alternative, lectin and GZMK complement pathways (PubMed:12878586, PubMed:18204047, PubMed:30643019, PubMed:39914456, PubMed:39814882, PubMed:6554279)
Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4Complement C3
go.drugbank.com/bio_entities/BE0003455TargetHumansPrecursor of non-enzymatic components of the classical, alternative, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and
Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1