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Digoxin
go.drugbank.com/drugs/DB00390ApprovedInvestigational[A178234] Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. … Digoxin is one of the oldest cardiovascular medications used today.[A178225] It is a common agent used to manage atrial fibrillation and the symptoms of heart failure.
Categories: Compounds used in a research, industrial, or household setting, P-glycoprotein substrates with a Narrow Therapeutic IndexInternational brands: Digocard-GBenzalkonium
go.drugbank.com/drugs/DB11105ApprovedInvestigationalBenzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent [FDA Label]. … This salt is used in a great variety of international pharmaceutical products such as eye, ear, and nasal drops or sprays as an excipient ingredient serving as an antimicrobial preservative [FDA Label]
Mixtures: Holy Water Mercy In A Bottle, Hands First 4 in 1Categories: Compounds used in a research, industrial, or household setting, Disinfectants (For Agents Used on Object)Headaches NEC
go.drugbank.com/conditions/DBCOND0026466Drugs: Acetaminophen · Acetylsalicylic acid · Bromopride · Brompheniramine · Caffeine · Carbaspirin calcium +15 moreSynonyms: Pain in head, [D]Pain in head NOSMethylmalonic aciduria type A protein, mitochondrial
go.drugbank.com/bio_entities/BE0000320TargetHumansAdditionally acts a reactivase by promoting the replacement of OH2Cbl by the active cofactor AdoCbl, restoring the activity of MMUT in the presence and hydrolysis of GTP (PubMed:21138732, PubMed:28943303 … Plays a dual role as both a protectase and a reactivase for MMUT (PubMed:21138732, PubMed:28943303).
Polypeptides: Methylmalonic aciduria type A protein, mitochondrialRibosomal small subunit pseudouridine synthase A
go.drugbank.com/bio_entities/BE0002034TargetEscherichia coli (strain K12)Responsible for synthesis of pseudouridine from uracil-516 in 16S ribosomal RNA.
Polypeptides: Ribosomal small subunit pseudouridine synthase ASynonyms: rRNA-uridine isomerase A, rRNA pseudouridylate synthase APeroxisomal acyl-coenzyme A oxidase 1
go.drugbank.com/bio_entities/BE0004135TargetEnzymeHumansMay play a role in peroxisomal beta-oxidation step in polyunsaturated fatty acids (PUFAs) biosynthesis. … Involved in VLCFA-dependent hepatic-to-adipose tissue inter-organ signaling in response to diet.
Polypeptides: Peroxisomal acyl-coenzyme A oxidase 1GABA(A) Receptor Benzodiazepine Binding Site
go.drugbank.com/bio_entities/BE0008668TargetHumansExtrasynaptic alpha-5-containing GABAARs in CA1 pyramidal neurons play a role in learning and memory processes (By similarity) … Gamma subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (By similarity).
Synonyms: GABA(A) receptor subunit alpha-1, GABA(A) receptor subunit alpha-2Function: GABA-A receptor activity, GABA-A receptor activityMHC class I HLA-A protein
go.drugbank.com/bio_entities/BE0010186TargetHumansPolypeptides: MHC class I HLA-A proteinSynonyms: HLA-AHepatitis A virus cellular receptor 2
go.drugbank.com/bio_entities/BE0010551TargetHumansExpressed on natural killer (NK) cells and acts as a coreceptor to enhance IFN-gamma production in response to LGALS9 (PubMed:22323453). … In contrast, shown to activate TCR-induced signaling in T-cells probably implicating ZAP70, LCP2, LCK and FYN (By similarity).
Polypeptides: Hepatitis A virus cellular receptor 2Acyl-coenzyme A thioesterase 2, mitochondrial
go.drugbank.com/bio_entities/BE0013225EnzymeHumansThe enzyme is involved in enhancing the hepatic fatty acid oxidation in mitochondria (By similarity) … Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:10944470, PubMed:16940157).
Polypeptides: Acyl-coenzyme A thioesterase 2, mitochondrialSynonyms: Acyl-coenzyme A thioester hydrolase 2a