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Hydroxyproline dehydrogenase
go.drugbank.com/bio_entities/BE0020644EnzymeHumansDoes not react with other diastereomers of Hyp: trans-4-D-hydroxyproline and cis-4-L-hydroxyproline. … Ubiquininone analogs such as menadione, duroquinone and ubiquinone-1 react more efficiently than oxygen as the terminal electron acceptor during catalysis
Synonyms: Kidney and liver proline oxidase 1Potassium channel subfamily T member 2
go.drugbank.com/bio_entities/BE0015626TargetHumansSodium-activated and chloride-activated potassium channel (PubMed:14684870, PubMed:16687497, PubMed:25214519, PubMed:27682982, PubMed:29069600, PubMed:29740868).
Synonyms: Sodium and chloride-activated ATP-sensitive potassium channel Slo2.1, Sequence like an intermediate conductance potassium channel subunitCyanocobalamin reductase / alkylcobalamin dealkylase
go.drugbank.com/bio_entities/BE0002175TargetHumansCobalamin (vitamin B12) cytosolic chaperone that catalyzes the reductive decyanation of cyanocob(III)alamin (cyanocobalamin, CNCbl) to yield cob(II)alamin and cyanide, using FAD or FMN as cofactors and … Cyanocobalamin constitutes the inactive form of vitamin B12 introduced from the diet, and is converted into the active cofactors methylcobalamin (MeCbl) involved in methionine biosynthesis, and 5'-deoxyadenosylcobalamin
Synonyms: Methylmalonic aciduria and homocystinuria type C proteinVesicular inhibitory amino acid transporter
go.drugbank.com/bio_entities/BE0002308TransporterHumansThe transport is equally dependent on the chemical and electrical components of the proton gradient (By similarity). May also transport beta-alanine (By similarity).
Synonyms: GABA and glycine transporterAll-trans-retinol 13,14-reductase
go.drugbank.com/bio_entities/BE0002320TargetHumansDoes not exhibit any activity toward all-trans-retinoic acid, nor 9-cis, 11-cis or 13-cis-retinol isomers. May play a role in the metabolism of vitamin A.
Synonyms: PPAR-alpha-regulated and starvation-induced gene proteinComplement C4-A
go.drugbank.com/bio_entities/BE0004685TargetHumansPrecursor of non-enzymatic components of the classical, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that
Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2Complement C4-B
go.drugbank.com/bio_entities/BE0004686TargetHumansPrecursor of non-enzymatic components of the classical, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that
Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
go.drugbank.com/bio_entities/BE0000525TargetHumansMay play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes (PubMed:15753091)
Synonyms: Gene associated with retinoic and IFN-induced mortality 19 protein, Gene associated with retinoic and interferon-induced mortality 19 proteinZinc transporter ZIP10
go.drugbank.com/bio_entities/BE0009884TransporterHumansPlays an important for both mature B-cell maintenance and humoral immune responses (By similarity). … When associated with SLC39A10, the heterodimer controls NCAM1 phosphorylation and integration into focal adhesion complexes during EMT (By similarity)
Synonyms: Zrt- and Irt-like protein 10RNA-splicing ligase RTCB
go.drugbank.com/bio_entities/BE0004442TargetHumansThese exon ends are then recognized and ligated by RTCB. … The ligation reaction, which requires guanosine triphosphate (GTP) and Mn(2+), proceeds through three metal-dependent steps.
Synonyms: RNA 2',3'-cyclic phosphate and 5'-OH ligase