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Displaying results 1551 - 1560 of 10000 in total
  1. Drug

    Simvastatin

    go.drugbank.com/drugs/DB00641
    ApprovedInvestigational

    events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks. … were found in clinical studies to result in a 45.8% to 54.6% decrease in LDL cholesterol levels, while simvastatin has been found to have an average decrease in LDL-C of ~35%.

    Categories: Hypolipidemic Agents Indicated for HyperlipidemiaProducts: ZOCOR FORT FILM TABLET, 28 ADET, Nu-simvastatin Tablets
  2. Drug

    Eosin

    go.drugbank.com/drugs/DB13706
    Investigational

    Categories: Compounds used in a research, industrial, or household settingProducts: EOSINA NA
  3. Drug

    Merbromin

    go.drugbank.com/drugs/DB13392
    Investigational

    It is an organomercuric disodium salt compound and a fluorescein that is available in many countries, except Switzerland, France, Germany, and the United States where the drug was withdrawn from market … due to the possibility of mercury poisoning.

    Products: MERBROMINA NA
  4. Drug

    Quetiapine

    go.drugbank.com/drugs/DB01224
    ApprovedInvestigational

    It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [clozapine] and [olanzapine].[A2189] … Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder.

    Mixtures: Seroquel XR, Seroquel XRCategories: Antidepressive Agents Indicated for Depression, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  5. Target

    Bile salt-activated lipase

    go.drugbank.com/bio_entities/BE0004523
    TargetEnzymeHumans

    Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins (PubMed:10220579, PubMed:27509211, PubMed:27650499,

    Polypeptides: Bile salt-activated lipaseSynonyms: Bile salt-stimulated lipase
  6. Indication

    Teething pain

    go.drugbank.com/conditions/DBCOND0024463
    Drugs: Benzocaine · Cetylpyridinium · Chamaemelum nobile flower · Choline salicylate
    Synonyms: Pain in tooth
  7. Target

    Bile salt hydrolase/transferase

    go.drugbank.com/bio_entities/BE0001392
    TargetClostridium perfringens (strain 13 / Type A)

    Shows a slight preference for taurine-conjugated bile acids as substrates (PubMed:7618863). … Acts as a bile salt hydrolase that catalyzes the deconjugation of glycine- and taurine-linked bile salts, which occurs naturally in the intestines of humans, releasing amino acid residues and deconjugated

    Polypeptides: Bile salt hydrolase/transferaseSynonyms: Bile salt hydrolase
  8. Drug

    Manganese cation

    go.drugbank.com/drugs/DB06757
    ApprovedInvestigationalNutraceutical

    [A263687, A263662] In humans, manganese regulates several physiological processes by acting as a cofactor for proteins [A263657, A263662, A263667] making it an essential metal for normal development and … [A263657] It is environmentally abundant, being the fifth most abundant metal and the twelfth most abundant element overall on Earth.

    Mixtures: ADDAMEL N FOR INFUSION, Megavite RxSynonyms: MANGANESE(II) ION, MANGANESE(II)
  9. Drug

    Clostridium botulinum

    go.drugbank.com/drugs/DB14223
    Investigational

    Products: DYSPORT FOR INJECTION 500 u/vial, DYSPORT FOR INJECTION 300u/vial
  10. Indication

    Emphysema

    go.drugbank.com/conditions/DBCOND0019688
    Drugs: Albuterol · Alpha-1-proteinase inhibitor · Bambuterol · Carmoterol · Fluticasone propionate · Guaifenesin +2 more
    Synonyms: Pathological accumulation of air in tissues