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Displaying results 151 - 160 of 5418 in total
  1. Target

    Epoxide hydrolase 1

    go.drugbank.com/bio_entities/BE0009565
    EnzymeHumans

    Binds 20(S)-hydroxycholesterol (20(S)-OHC) (By similarity)

  2. Target

    Hydroxyacylglutathione hydrolase, mitochondrial

    go.drugbank.com/bio_entities/BE0001825
    TargetHumans

    Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid

  3. Target

    Cell division cycle 7-related protein kinase

    go.drugbank.com/bio_entities/BE0010851
    TargetHumans

    Phosphorylates critical substrates that regulate the G1/S phase transition and initiation of DNA replication, such as MCM proteins and CLASPIN

  4. Target

    ATP-binding cassette sub-family C member 10

    go.drugbank.com/bio_entities/BE0003651
    TransporterHumans

    ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Lipophilic anion transporter that mediates ATP-dependent transport of glucuronide conjugates s...

    Function: ABC-type glutathione S-conjugate transporter activity
  5. Target

    Serine/threonine-protein kinase Nek9

    go.drugbank.com/bio_entities/BE0009500
    TargetHumans

    Important for G1/S transition and S phase progression (PubMed:12840024, PubMed:14660563, PubMed:19941817).

  6. Target

    L-methionine gamma-lyase

    go.drugbank.com/bio_entities/BE0003208
    TargetEnzymePseudomonas putida

    Thus, the enzyme is able to cleave C-S, C-Se, and C-O bonds of sulfur, selenium, and oxygen amino acids, respectively (PubMed:22785484, PubMed:6742420). … derivatives, O-substituted-L-homoserines and DL-selenomethionine, and, to a lesser extent, alpha,beta-elimination and beta-replacement reactions of L-cysteine, S-methyl-L-cysteine, and O-acetyl-L-serine

  7. Target

    MIO-dependent tyrosine 2,3-aminomutase

    go.drugbank.com/bio_entities/BE0003755
    TargetStreptomyces globisporus

    Catalyzes the MIO-dependent deamination of L-tyrosine generating the corresponding alpha,beta-unsaturated acid, (S)-beta-tyrosine.

  8. Target

    Spermidine synthase

    go.drugbank.com/bio_entities/BE0000300
    EnzymeHumans

    Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM).

  9. Target

    ATP-binding cassette sub-family C member 2

    go.drugbank.com/bio_entities/BE0001069
    TargetTransporterHumans

    ATP-dependent transporter of the ATP-binding cassette (ABC) family that hydrolyzes ATP to enable active transport of substrates conjugated with glucuronate, glutathione or sulfate. Operates at apical membranes of polarized cells such as ...

    Function: ABC-type glutathione S-conjugate transporter activity
  10. Target

    ATP-binding cassette sub-family C member 11

    go.drugbank.com/bio_entities/BE0003658
    TransporterHumans

    Mediates the ATP-dependent efflux of a range of physiological lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates, such as dehydroepiandrosterone … Participates in the secretion of odorants and their precursors from the apocrine sweat glands, including the secretion of glutamine conjugates, as well as the Cys-Gly-(S) conjugates of 3-methyl-3-sulfanyl-hexanol