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Displaying results 1671 - 1680 of 10000 in total
  1. Drug

    Procainamide

    go.drugbank.com/drugs/DB01035
    Approved

    A derivative of procaine with less CNS action.

    Categories: Antiarrhythmics, Class I, Antiarrhythmics, Class IaSynonyms: p-Amino-N-(2-diethylaminoethyl)benzamide, p-Aminobenzoic diethylaminoethylamide
  2. Drug

    Racepinephrine

    go.drugbank.com/drugs/DB11124
    Approved

    Racepinephrine is a racemic mixture consisting of d-[DB00668] and l-[DB00668] enantiomers. Epinephrine is a non-selective α- and β-adrenergic receptor agonist. … It is a bronchodilator used in the temporary relief of mild symptoms of intermittent asthma including wheezing, tightness of chest and shortness of breath.

    Mixtures: Racord Two No 8, Racord Two No 9Categories: Adrenergic alpha-1 Receptor Agonists, Adrenergic alpha-2 Receptor Agonists
  3. Indication

    Increased Intra Ocular Pressure (IOP)

    go.drugbank.com/conditions/DBCOND0049485
    Drugs: Betaxolol · Bimatoprost · Brimonidine · Brinzolamide · Carbamoylcholine · Carteolol +11 more
    Synonyms: Increase in intraocular pressure, Elevation in intraocular pressure
  4. Target

    Methylated-DNA--protein-cysteine methyltransferase

    go.drugbank.com/bio_entities/BE0001145
    TargetHumans

    Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. … Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated

    Synonyms: 6-O-methylguanine-DNA methyltransferase, O-6-methylguanine-DNA-alkyltransferase
  5. Indication

    Sore Throat

    go.drugbank.com/conditions/DBCOND0033906
    Drugs: Amylmetacresol · Amylocaine · Benzocaine · Benzoic acid · Cetrimonium · Cetylpyridinium +20 more
    Synonyms: Pain in throat, Pain in the pharynx
  6. Indication

    Chronic Phase Chronic Myeloid Leukemia

    go.drugbank.com/conditions/DBCOND0057382
    Drugs: Asciminib · Bosutinib · Dasatinib · Daunorubicin · Nilotinib · Ponatinib
    Synonyms: CML in Chronic Phase, Chronic Myeloid Leukemia in Chronic Phase
  7. Drug

    Isoflurane

    go.drugbank.com/drugs/DB00753
    ApprovedInvestigationalVet approved

    A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether
  8. Drug

    Tofacitinib

    go.drugbank.com/drugs/DB08895
    ApprovedInvestigational

    It is approved by the FDA for treatment of moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate. … Tofacitinib is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: XELJANZ® XR 11 MG TABLETAS DE LIBERACIÓN MODIFICADA, XELJANZ®5MG
  9. Drug

    Fluticasone furoate

    go.drugbank.com/drugs/DB08906
    ApprovedInvestigational

    Fluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications[FDA Label][F4364]. Fluticasone furoate was first approved in 2007[L5965].

    Mixtures: RELVAR® ELLIPTA® 100MCG/25MCG, RELVAR® ELLIPTA ® 200MCG/25MCG POLVO PARA INHALACIÓNCategories: Agents to Treat Airway Disease, P-glycoprotein inducers
  10. Indication

    Nausea caused by Chemotherapy

    go.drugbank.com/conditions/DBCOND0148446
    Drugs: Palonosetron
    Synonyms: C/O - nausea