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Displaying results 1691 - 1700 of 10000 in total
  1. Drug

    Petrolatum

    go.drugbank.com/drugs/DB11058
    ApprovedInvestigational

    A colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.

    Mixtures: S-Oint DIAPER RASH AND SKIN PROTECTANT, Veradex-ECategories: Compounds used in a research, industrial, or household setting
  2. Drug

    Phenaridine

    go.drugbank.com/drugs/DB09178
    ExperimentalIllicit

    Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue … Phenaridine (2,5-Dimethylfentanyl) is a synthetic fentanyl derivative opioid. It was developed in 1972, and is used for surgical anasthesia in Russia. Phenaridine has similar effects to fentanyl.

    Categories: Heterocyclic Compounds, 1-Ring
  3. Pathway

    Methylphenidate Norepinephrine Reuptake Inhibitor Action Pathway

    smpdb.ca/view/SMP0126572
    Drug action

    Methylphenidate, known commonly as Ritalin, is a central nervous system stimulant used mainly for ADHD, but also for narcolepsy. ADHD is caused by an abnormality in the dopamine transporter gene (DAT1), the D4 receptor gene (DRD-4), and/...

    Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · ATP · Norepinephrine · Methylphenidate +7 more
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  4. Pathway

    Asenapine Dopamine Antagonist Action Pathway

    smpdb.ca/view/SMP0126736
    Drug action

    Asenapine is a serotonin, dopamine, noradrenaline, and histamine antagonist in which asenapine possess more potent activity with serotonin receptors than dopamine. Asenapine is an atypical antipsychotic multireceptor neuroleptic drug whi...

    Drugs: Pyridoxal phosphate · Tyrosine · ATP · Dopamine · Levodopa · Calcium +3 more
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  5. Pathway

    Nomifensine Dopamine Reuptake Inhibitor Action Pathway

    smpdb.ca/view/SMP0127002
    Drug action

    Nomifensine, formerly known as Merital capsules, is a dopamine reuptake inhibitor drug that was removed from the market in 1986 for increased incidence of hemolytic anemia. The drug was originally used to treat depression. Nomifensine st...

    Drugs: Pyridoxal phosphate · Tyrosine · ATP · Dopamine · Levodopa · Calcium +4 more
    Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
  6. Drug

    Sodium phosphate, monobasic, unspecified form

    go.drugbank.com/drugs/DB14503
    Approved

    Mixtures: Ready-to-Use, Ready-to-Use Enema
  7. Drug

    St. John's Wort

    go.drugbank.com/drugs/DB01323
    ApprovedInvestigationalNutraceutical

    Synonyms: St Johns Wort, St john's wortMixtures: S. R. Formula
  8. Drug

    Isradipine

    go.drugbank.com/drugs/DB00270
    Approved

    It is structurally related to felodipine, nifedipine, and nimodipine and is the most potent calcium-channel blocking agent of the DHP class. … It exhibits greater selectivity towards arterial smooth muscle cells owing to alternative splicing of the alpha-1 subunit of the channel and increased prevalence of inactive channels in smooth muscle cells

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: OPTASIL ®, CALBLOCK® TABLETAS
  9. Drug

    Bisoprolol

    go.drugbank.com/drugs/DB00612
    ApprovedInvestigational

    [A180472,L7219] It is considered a potent drug with a long-half life that can be used once daily to reduce the need for multiple doses of antihypertensive drugs. … [A180472] Bisoprolol is generally well tolerated, likely due to its β1-adrenergic receptor selectivity and is a useful alternative to non-selective β-blocker drugs in the treatment of hypertension such

    Mixtures: BISOPROLOLO E IDROCLOROTIAZIDE AUROBINDO, BISOPROLOLO E IDROCLOROTIAZIDE AUROBINDOCategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  10. Drug

    Meloxicam

    go.drugbank.com/drugs/DB00814
    ApprovedInvestigationalVet approved

    It is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract effects, however, this is a topic of controversy.[A190198,A190201] … Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve various types of pain, including pain caused by musculoskeletal conditions, osteoarthritis, and rheumatoid arthritis.

    Mixtures: OCAM PROTECT® 7.5 TABLETAS DE LIBERACIÓN RETARDADA, OCAM PROTECT ® 15 MG TABLETAS DE LIBERACION RETARDADACategories: COX-2 Inhibitors, Cytochrome P-450 Substrates