Search

Displaying results 1911 - 1920 of 10000 in total
  1. Drug

    Camizestrant

    go.drugbank.com/drugs/DB19218
    ApprovedInvestigational

    [L64117,L64107,L64116] It is the first next-generation oral SERD and complete ER antagonist approved in the first-line setting, and the only one approved for use with all three widely approved CDK4/6 inhibitors … [L64094,L64107] Patients are selected for treatment on the basis of an *ESR1* mutation detected by circulating tumor DNA testing during first-line endocrine therapy, before radiographic disease progression

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 3-pyridinamine, n-(1-(3-fluoropropyl)-3-azetidinyl)-6-((6s,8r)-6,7,8,9-tetrahydro-8-methyl-7-(2,2,2-trifluoroethyl)-3h-pyrazolo(4,3-f)isoquinolin-6-yl)-, N-(1-(3-fluoropropyl)-3-azetidinyl)-6-((6s,8r)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydro-3h-pyrazolo(4,3-f)isoquinolin-6-yl)-3-pyridinamine
  2. Indication

    Hypertension

    go.drugbank.com/conditions/DBCOND0020037
    Drugs: Acebutolol · Aliskiren · Amiloride · Amlodipine · Ammonium chloride · Aprocitentan +78 more
    Synonyms: Rise in BP, Rise in blood pressure
  3. Drug

    Hydroxide ion

    go.drugbank.com/drugs/DB14522
    Investigational

    Mixtures: OHTrust Nano Ion WaterSynonyms: Hydroxide ion
  4. Drug

    Afatinib

    go.drugbank.com/drugs/DB08916
    ApprovedInvestigational

    Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available as Boehringer Ingelheim's brand name Gilotrif [FDA Label]. … For oral use, afatinib tablets are a first-line (initial) treatment for patients with metastatic non-small cell lung cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations as detected

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: GIOTRIF® 30 MG, GIOTRIF® 40 MG
  5. Target

    Mitogen-activated protein kinase kinase kinase 19

    go.drugbank.com/bio_entities/BE0009408
    TargetHumans

    Synonyms: Regulated in COPD, protein kinase
  6. Drug

    Sennosides

    go.drugbank.com/drugs/DB11365
    ApprovedInvestigational

    Sennoside A, one of the sennosides present in the laxative medication, has recently proven effective in inhibiting the ribonuclease H (RNase H) activity of human immunodeficiency virus (HIV) reverse transcriptase … The medication is taken by mouth or via the rectum[FDA Label]. It typically begins working in minutes when given by rectum and within twelve hours when given by mouth[FDA Label].

    Salts: Sennosides A and BMixtures: 2 In 1laxative Stool Softener and Stiulant Laxative, 2 In 1laxative Stool Softener and Stiulant Laxative
  7. Target

    SPARC

    go.drugbank.com/bio_entities/BE0002145
    TargetHumans

    Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites;...

    Synonyms: Secreted protein acidic and rich in cysteine
  8. Drug

    Copper

    go.drugbank.com/drugs/DB09130
    ApprovedInvestigational

    Copper is a transition metal and a trace element in the body. It is important to the function of many enzymes including cytochrome c oxidase, monoamine oxidase and superoxide dismutase [FDA Label]. … Copper is commonly used in contraceptive intrauterine devices (IUD) [L801].

    Mixtures: Calcium With Mg Zn Mn Cu CR Si and Vit. C & D, Multi II IV Vi TabProducts: ParaGard T 380A
  9. Indication

    Sloughing Skin

    go.drugbank.com/conditions/DBCOND0111504
    Drugs: Phentolamine
    Synonyms: Changes in skin texture
  10. Indication

    Traveler's Diarrhea

    go.drugbank.com/conditions/DBCOND0040361
    Drugs: Azithromycin · Bismuth subsalicylate · Loperamide · Norfloxacin · Ofloxacin · Rifaximin
    Synonyms: Acute Gastroenteritis in Adult Travelers