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Displaying results 11 - 20 of 427 in total
  1. Target

    Betaine--homocysteine S-methyltransferase 1

    go.drugbank.com/bio_entities/BE0000845
    TargetHumans

    Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline

    Polypeptides: Betaine--homocysteine S-methyltransferase 1Function: betaine-homocysteine S-methyltransferase activity
  2. Target

    Sodium- and chloride-dependent betaine transporter

    go.drugbank.com/bio_entities/BE0004777
    TargetTransporterHumans

    Transporter that mediates cellular uptake of betaine and GABA in a sodium- and chloride-dependent process (PubMed:7589472).

    Polypeptides: Sodium- and chloride-dependent betaine transporterSynonyms: Na(+)/Cl(-) betaine/GABA transporter
  3. Target

    S-methylmethionine--homocysteine S-methyltransferase BHMT2

    go.drugbank.com/bio_entities/BE0002249
    TargetEnzymeHumans

    Involved in the regulation of homocysteine metabolism. Converts homocysteine to methionine using S-methylmethionine (SMM) as a methyl donor

    Synonyms: Betaine--homocysteine S-methyltransferase 2
  4. Target

    Alpha-aminoadipic semialdehyde dehydrogenase

    go.drugbank.com/bio_entities/BE0000135
    TargetHumans

    Involved in cellular defense against hyperosmotic stress by metabolizing betaine aldehyde to betaine, an important cellular osmolyte and methyl donor (PubMed:20207735)

    Synonyms: Betaine aldehyde dehydrogenase
  5. Pathway

    Betaine Metabolism

    smpdb.ca/view/SMP0000123
    Metabolic

    Then, betaine aldehyde dehydrogenase oxidizes betaine aldehyde to betaine in the mitochondria or cytoplasm. … Betaine is obtained from diet as betaine or compounds containing choline in foods such as whole grains, beets and spinach. Betaine can also be synthesized from choline in the liver and kidney.

    Drugs: Tetrahydrofolic acid · Ademetionine · Choline · Methionine · NADH · ATP +8 more
    Enzymes: Betaine--homocysteine S-methyltransferase 1
  6. Pathway

    Betaine Drug Metabolism

    smpdb.ca/view/SMP0124744
    Metabolic

    Betaine is obtained from foods such as wheat, shellfish, spinach, and beets. In the intestine, betaine is metabolized to trimethylamine (TMA) by the gut microbiota (Peptoclostridium acidaminophilum). … TMA is created from betaine via the enzyme betaine reductase in the intestinal microbe, then TMA then enters the bloodstream and is transported to the liver where dimethylaniline monooxygenase [N-oxide-forming

    Drugs: Acetylphosphate · Flavin adenine dinucleotide
  7. Drug

    Pepsin

    go.drugbank.com/drugs/DB13198
    ApprovedWithdrawn

    Pepsin is a potent enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, and dairy products . Studies on gastric digestion from 1820-1840 led to the discovery of pepsin as the substance which, in the presence ...

    Mixtures: Betaine HCl and Pepsin, Glutamic Acid HCl Betaine HCl W Pepsin
  8. Indication

    Homocystinuria due to cobalamin cofactor metabolism (cbl) defect

    go.drugbank.com/conditions/DBCOND0151379
    Drugs: Betaine
  9. Indication

    Homocystinuria

    go.drugbank.com/conditions/DBCOND0000908
    Drugs: Betaine
  10. Indication

    Homocystinuria Due to Cystathionine Beta-Synthase Deficiency

    go.drugbank.com/conditions/DBCOND0144713
    Drugs: Betaine