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Displaying results 2321 - 2330 of 6196 in total
  1. Target

    Inactive phospholipase C-like protein 1

    go.drugbank.com/bio_entities/BE0001081
    TargetHumans

    Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A recepto...

    Synonyms: Phospholipase C-related but catalytically inactive protein
  2. Drug

    Temocapril

    go.drugbank.com/drugs/DB08836
    Investigational

    Temocapril can also be used in hemodialysis patients without risk of serious accumulation. … Temocapril is a prodrug-type angiotensin-I converting enzyme (ACE) inhibitor not approved for use in the United States, but is approved in Japan and South Korea.

  3. Indication

    Cardiac Arrest

    go.drugbank.com/conditions/DBCOND0031003
    Drugs: Isoprenaline · Norepinephrine
    Synonyms: Cardiac Arrest (CA), CA - Cardiac arrest
  4. Drug

    Abaloparatide

    go.drugbank.com/drugs/DB05084
    ApprovedInvestigational

    Abaloparatide is an N-terminal analog of parathyroid hormone-related protein (PTHrP) [A256778] and an agonist at the parathyroid hormone type 1 (PTH1) receptor. … [A256778] Abaloparatide is an osteoanabolic agent that stimulates bone formation.

  5. Drug

    Lisuride

    go.drugbank.com/drugs/DB00589
    Approved

    An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). … It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists).

  6. Drug

    Albendazole

    go.drugbank.com/drugs/DB00518
    ApprovedInvestigationalVet approved

    A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)

    Products: K-Worm Choc Chewtab 200 mg, K-Worm Choc Suspension 400mg/10ml
  7. Drug

    Poa pratensis pollen

    go.drugbank.com/drugs/DB10366
    Approved

    Poa pratensis pollen is the pollen of the Poa pratensis plant. Poa pratensis pollen is mainly used in allergenic testing.

    Mixtures: K-O-T Standardized Grass Pollen Mix, K-O-T Standardized Grass Pollen Mix
  8. Indication

    Advanced Prostate Cancer

    go.drugbank.com/conditions/DBCOND0043429
    Drugs: Degarelix · Histrelin · Leuprolide · Relugolix · Triptorelin
    Synonyms: Ca prostate, CA - Cancer of prostate
  9. Drug

    Imlifidase

    go.drugbank.com/drugs/DB15258
    ApprovedInvestigational

    [A225836,A225921] Imlifidase is a cysteine protease and eliminates Fc-dependent effector functions such as CDC and ADCC by cleaving the heavy chains of human immunoglobulin G (IgG) antibodies. … [A225836] As a result, highly sensitized individuals experience marked delays on transplant lists due to the challenges associated with procuring an HLA compatible donor graft.

  10. Drug

    MK-8666

    go.drugbank.com/drugs/DB14937
    Investigational

    MK-8666 is under investigation in clinical trial NCT01971554 (Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of MK-8666 in Participants With Type 2 Diabetes Mellitus (MK-8666-003)).