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Displaying results 251 - 260 of 1485 in total
  1. Drug

    Tadalafil

    go.drugbank.com/drugs/DB00820
    ApprovedInvestigational

    Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy. It was first approved in 2003 by the FDA for use ...

    Products: LUDIKA TABLETAS RECUBIERTAS POR 20 MG
  2. Target

    DNA repair nuclease/redox regulator APEX1

    go.drugbank.com/bio_entities/BE0002414
    TargetHumans

    Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 are DNA repair and redox regulation of transcriptional factors (PubMed:11118054, PubMed:11452037, PubMed:15...

    Synonyms: DNA-(apurinic or apyrimidinic site) endonuclease
  3. Indication

    Methicillin Susceptible Staphylococcus Aureus (MSSA) Infection

    go.drugbank.com/conditions/DBCOND0132980
    Drugs: Omadacycline
    Synonyms: Staphylococcal infection, unspecified site
  4. Drug

    Pralidoxime

    go.drugbank.com/drugs/DB00733
    ApprovedInvestigationalVet approved

    Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme.

  5. Target

    BCL11 transcription factor A

    go.drugbank.com/bio_entities/BE0019545
    TargetHumans

    Transcription factor (PubMed:16704730, PubMed:29606353). Associated with the BAF SWI/SNF chromatin remodeling complex (PubMed:23644491, PubMed:39607926). Binds to the 5'-TGACCA-3' sequence motif in regulatory regions of target genes, inc...

    Synonyms: Ecotropic viral integration site 9 protein homolog
  6. Drug

    Azatadine

    go.drugbank.com/drugs/DB00719
    ApprovedWithdrawn

    Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. … The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury

  7. Drug

    Atorvastatin

    go.drugbank.com/drugs/DB01076
    ApprovedInvestigational

    The evidence supporting statin use, coupled with minimal side effects and long term benefits, has resulted in wide use of this medication in North America. … [T568] It is a pentasubstituted pyrrole [A177415] formed by two contrasting moieties with an achiral heterocyclic core unit and a 3,5-dihydroxypentanoyl side chain identical to its parent compound.

    Products: ATORVASTATIN PUR 30MG, ATORVASTATIN PUR 60MG
  8. Indication

    Joint Pain

    go.drugbank.com/conditions/DBCOND0035084
    Drugs: (+)-menthol · (S)-camphor · Borneol · Camphor · Diclofenac · Ephedrine +14 more
    Synonyms: Pain in joint, site unspecified
  9. Drug

    Chloroxylenol

    go.drugbank.com/drugs/DB11121
    Approved

    Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. ...

    Products: Suite Scrub Foam Liq 3%, Suite Scrub 1000 Liq 3%
  10. Indication

    Osteoarthritis of the Knee

    go.drugbank.com/conditions/DBCOND0032623
    Drugs: Diacerein · Diclofenac · Dimethyl sulfone · Duloxetine · Glucosamine · Hyaluronic acid +1 more
    Synonyms: Osteoarthritis, unspecified site, Unspecified osteoarthritis, unspecified site