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Displaying results 2761 - 2770 of 10000 in total
  1. Target

    Retinol dehydrogenase 5

    go.drugbank.com/bio_entities/BE0000570
    TargetEnzymeHumans

    Plays a significant role in 11-cis retinol oxidation in the retinal pigment epithelium cells (RPE). … Catalyzes the oxidation of cis-isomers of retinol, including 11-cis-, 9-cis-, and 13-cis-retinol in an NAD-dependent manner (PubMed:10588954, PubMed:11675386, PubMed:9115228, PubMed:9931293).

    Polypeptides: Retinol dehydrogenase 5Synonyms: Short chain dehydrogenase/reductase family 9C member 5
  2. Target

    Peroxiredoxin-5, mitochondrial

    go.drugbank.com/bio_entities/BE0000907
    TargetEnzymeHumans

    Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events

    Polypeptides: Peroxiredoxin-5, mitochondrialSynonyms: Thioredoxin-dependent peroxiredoxin 5
  3. Target

    5-aminolevulinate synthase

    go.drugbank.com/bio_entities/BE0002158
    TargetHumans

    Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products.

    Polypeptides: 5-aminolevulinate synthaseSynonyms: 5-aminolevulinic acid synthase
  4. Target

    Integrin alpha-5

    go.drugbank.com/bio_entities/BE0008988
    TargetHumans

    Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands.

    Polypeptides: Integrin alpha-5Synonyms: VLA-5
  5. Target

    Thyroxine 5-deiodinase

    go.drugbank.com/bio_entities/BE0009333
    TargetEnzymeHumans

    Plays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination (PubMed:7593630, PubMed:12586771, PubMed:12746313, PubMed:18821722 … T1), rT3 to 3',5'-diiodothyronine (3',5'-T2) and 3,3'-T2 to 3'-monoiodothyronine (3'-T1) via inner-ring deiodination (IRD) (PubMed:7593630, PubMed:12586771, PubMed:12746313, PubMed:18821722, PubMed:18339710

    Polypeptides: Thyroxine 5-deiodinaseFunction: thyroxine 5'-deiodinase activity
  6. Target

    Pseudouridine-5'-phosphatase

    go.drugbank.com/bio_entities/BE0014361
    EnzymeHumans

    Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine

    Polypeptides: Pseudouridine-5'-phosphataseSynonyms: 5'-PsiMPase, Pseudouridine-5'-monophosphatase
  7. Target

    NADPH oxidase 5

    go.drugbank.com/bio_entities/BE0018640
    TargetHumans

    May play a role in cell growth and apoptosis (PubMed:12686516)

    Polypeptides: NADPH oxidase 5
  8. Target

    Camphor 5-monooxygenase

    go.drugbank.com/bio_entities/BE0001246
    TargetPseudomonas putida

    Involved in a camphor oxidation system.

    Polypeptides: Camphor 5-monooxygenaseFunction: camphor 5-monooxygenase activity
  9. Indication

    Fat occlusion in central venous catheter

    go.drugbank.com/conditions/DBCOND0022419
    Drugs: Ethanol
    Synonyms: Fat occlusion in central venous catheter
  10. Indication

    Sensation of burning in the eyes

    go.drugbank.com/conditions/DBCOND0098350
    Drugs: Glycerin · Hyaluronic acid · Loratadine · Tetryzoline
    Synonyms: Burning in eyes, Burning sensation in eyes