Search
Protein S100-A9
go.drugbank.com/bio_entities/BE0008993TargetHumansActivates NADPH-oxidase by facilitating the enzyme complex assembly at the cell membrane, transferring arachidonic acid, an essential cofactor, to the enzyme complex and S100A8 contributes to the enzyme … The iNOS-S100A8/A9 transnitrosylase complex is proposed to also direct selective inflammatory stimulus-dependent S-nitrosylation of multiple targets such as ANXA5, EZR, MSN and VIM by recognizing a [IL
Synonyms: Leukocyte L1 complex heavy chainSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial
go.drugbank.com/bio_entities/BE0002257TargetEnzymeHumansMembrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to
Synonyms: Succinate dehydrogenase complex subunit CCyclin-dependent kinase 9
go.drugbank.com/bio_entities/BE0002207TargetHumansThis complex is inactive when in the 7SK snRNP complex form (PubMed:10574912, PubMed:10757782, PubMed:11145967, PubMed:11575923, PubMed:11809800, PubMed:11884399, PubMed:14701750, PubMed:16109376, PubMed … The CDK9/cyclin-K complex has also a kinase activity towards CTD of RNAP II and can substitute for CDK9/cyclin-T P-TEFb in vitro (PubMed:21127351).
Synonyms: Tat-associated kinase complex catalytic subunitProteasome subunit beta type-5
go.drugbank.com/bio_entities/BE0002348TargetHumansWithin the 20S core complex, PSMB5 displays a chymotrypsin-like activity … Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.
Synonyms: Multicatalytic endopeptidase complex epsilon chainProteasome subunit beta type-4
go.drugbank.com/bio_entities/BE0003918TargetHumansNon-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
Synonyms: Multicatalytic endopeptidase complex beta chainProteasome subunit beta type-8
go.drugbank.com/bio_entities/BE0004739TargetHumansThe proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic
Synonyms: Multicatalytic endopeptidase complex subunit C13Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial
go.drugbank.com/bio_entities/BE0002252TargetHumansMembrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to
Synonyms: Succinate dehydrogenase complex subunit DProteasome subunit alpha type-1
go.drugbank.com/bio_entities/BE0003910TargetHumansComponent of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)
Synonyms: Multicatalytic endopeptidase complex subunit C2Proteasome subunit beta type-9
go.drugbank.com/bio_entities/BE0004737TargetHumansThe proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic
Synonyms: Multicatalytic endopeptidase complex chain 7Lysine-specific histone demethylase 1A
go.drugbank.com/bio_entities/BE0010091TargetHumansComponent of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development (PubMed:16079794, PubMed:16140033
Synonyms: BRAF35-HDAC complex protein BHC110