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Metabolism and Physiological Effects of Citrulline
smpdb.ca/view/SMP0126861Metabolicwax beans, and potato. … during cell death and tissue inflammation.
Metabolism and Physiological Effects of Putrescine
smpdb.ca/view/SMP0123276Metabolicwhich can eventually lead to anemia. … While putrescine is important for interactions and processes involving, DNA, RNA and proteins, at high levels it is also a protein bound uremic toxin found in the body that can inhibit erythropoietin production
Metabolism and Physiological Effects of Xanthosine
smpdb.ca/view/SMP0124866MetabolicThe purines are guanine and adenine. These undergo metabolism in the liver to form xanthosine. Adenine forms adenosine through the enzyme purine nucleoside phosphorylase. … Xanthosine then enters the blood where it can have detrimental effects on other organs such as the kidney, causing renal failure and the heart causing cardiovascular disease.
Metabolism and Physiological Effects of Uridine
smpdb.ca/view/SMP0124871MetabolicMore specifically, uridine is a nucleoside consisting of uracil and D-ribose and a component of RNA. … L-glutamine is first converted to carbamoyl phosphate then to N-Carbamoyl-L-aspartate and finally to dihydroorotate by the CAD protein (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and
D-Arginine and D-Ornithine Metabolism
smpdb.ca/view/SMP0000036MetabolicD-Amino acids have been show to be present in high concentrations in humans and play a role in biological functions. … DAAO is highly specific towards D-amino acids and favours free neutral D-amino acids or those with hydrophobic, polar or aromatic groups. Acidic amino acids are not catalyze by DAOO.
Metabolism and Physiological Effects of Phenylacetylglutamine
smpdb.ca/view/SMP0123208MetabolicPhenylacetyl-CoA and L-glutamine react to form phenylacetylglutamine and coenzyme A. … Phenylacetylglutamine is a product formed from the conjugation of phenylacetate and glutamine.
Drugs: Phenylalanine · L-Glutamine · Adenosine phosphate · ATP · Magnesium cation · Phenylpyruvic acid +1 moreMetabolism and Physiological Effects of Phenol
smpdb.ca/view/SMP0123255MetabolicPhenol is shown to cause cardiovascular disease and enhance the production of reactive oxygen species and cause oxidative stress. … Phenol can get further metabolized in a liver hepatocyte to Phenyl sulphate and Phenyl glucuronide. However phenol itself is shown to be a major uremic toxin through high levels of retention.
Metabolism and Physiological Effects of Choline
smpdb.ca/view/SMP0124739MetabolicCholine is obtained from foods like poultry, meat, fish, dairy and eggs. … TMAO has negative effects on organs such as the heart, kidney and vascular system by contributing to cardiovascular disease, atherosclerosis, endothelial dysfunction and kidney disease.
Metabolism and Physiological Effects of Dimethylglycine
smpdb.ca/view/SMP0124873MetabolicDimethylglycine (DMG) is an amino acid derivative found in the cells of all plants and animals and can be obtained in the diet in small amounts from grains and meat. … Dimethylglycine enters the bloodstream and can cause toxic effects on the cardiovascular system.
Drugs: Choline · Methionine · NADH · Zinc · N,N-dimethylglycine · Flavin adenine dinucleotide +1 moreMetabolism and Physiological Effects of Phenylacetylglycine
smpdb.ca/view/SMP0126858MetabolicPhenylacetic acid may arise from exposure to styrene (plastic) or through the consumption of fruits and vegetables. … The presence of phenylacetylglycine in urine has been confirmed for dogs, rats and mice. However, the presence of this compound in human urine is controversial.
Drugs: Glycine