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Displaying results 21 - 30 of 225 in total
  1. Target

    Carnitine O-palmitoyltransferase 2, mitochondrial

    go.drugbank.com/bio_entities/BE0000179
    TargetHumans

    Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters (PubMed:20538056) … Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation

    Polypeptides: Carnitine O-palmitoyltransferase 2, mitochondrial
  2. Target

    Protein-L-isoaspartate O-methyltransferase

    go.drugbank.com/bio_entities/BE0002532
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. … It plays a role in the repair and/or degradation of damaged proteins.

    Polypeptides: Protein-L-isoaspartate O-methyltransferaseFunction: protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
  3. Target

    Protein-S-isoprenylcysteine O-methyltransferase

    go.drugbank.com/bio_entities/BE0011941
    EnzymeHumans

    Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues

    Polypeptides: Protein-S-isoprenylcysteine O-methyltransferaseFunction: protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
  4. Target

    Protein-serine O-palmitoleoyltransferase porcupine

    go.drugbank.com/bio_entities/BE0019221
    TargetHumans

    Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1(9Z)), to Wnt

    Polypeptides: Protein-serine O-palmitoleoyltransferase porcupine
  5. Target

    O-phosphoseryl-tRNA(Sec) selenium transferase

    go.drugbank.com/bio_entities/BE0002171
    TargetHumans

    Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis

    Polypeptides: O-phosphoseryl-tRNA(Sec) selenium transferaseFunction: O-phosphoseryl-tRNA(Sec) selenium transferase activity
  6. Target

    Membrane-bound glycerophospholipid O-acyltransferase 2

    go.drugbank.com/bio_entities/BE0015719
    EnzymeHumans

    ) and lysophosphatidylserine (LPS) (PubMed:18772128). … Acyltransferase which catalyzes the transfer of an acyl group from an acyl-CoA to a lysophospholipid leading to the production of a phospholipid and participates in the reacylation step of the phospholipid

    Polypeptides: Membrane-bound glycerophospholipid O-acyltransferase 2Synonyms: 1-acylglycerophosphate O-acyltransferase MBOAT2, 1-acylglycerophosphocholine O-acyltransferase MBOAT2
  7. Target

    Carnitine O-palmitoyltransferase 1, muscle isoform

    go.drugbank.com/bio_entities/BE0017721
    TargetHumans

    Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation

    Polypeptides: Carnitine O-palmitoyltransferase 1, muscle isoformSynonyms: Carnitine O-palmitoyltransferase I, muscle isoform
  8. Target

    Carnitine O-palmitoyltransferase 1, liver isoform

    go.drugbank.com/bio_entities/BE0000406
    TargetHumans

    Also possesses a lysine succinyltransferase activity that can regulate enzymatic activity of substrate proteins such as ENO1 and metabolism independent of its classical carnitine O-palmitoyltransferase … Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation

    Polypeptides: Carnitine O-palmitoyltransferase 1, liver isoformSynonyms: Carnitine O-palmitoyltransferase I, liver isoform
  9. Target

    UDP-3-O-acyl-N-acetylglucosamine deacetylase

    go.drugbank.com/bio_entities/BE0001333
    TargetAquifex aeolicus (strain VF5)

    Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

    Polypeptides: UDP-3-O-acyl-N-acetylglucosamine deacetylaseSynonyms: UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
  10. Target

    Heparan sulfate glucosamine 3-O-sulfotransferase 3A1

    go.drugbank.com/bio_entities/BE0001541
    TargetHumans

    Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2 (PubMed:10520990, PubMed:15304505, PubMed:9988768). … The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry (PubMed:10520990).

    Polypeptides: Heparan sulfate glucosamine 3-O-sulfotransferase 3A1Synonyms: Heparan sulfate 3-O-sulfotransferase 3A1, Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1