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Displaying results 21 - 30 of 2763 in total
  1. Target

    Receptor-type tyrosine-protein phosphatase C

    go.drugbank.com/bio_entities/BE0010406
    TargetHumans

    Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor (PubMed:35767951). Acts as a positive regulator of T-cell coactivation upon binding to DPP4.

    Polypeptides: Receptor-type tyrosine-protein phosphatase C
  2. Target

    Outer membrane porin C

    go.drugbank.com/bio_entities/BE0009852
    TransporterEscherichia coli (strain K12)

    Forms pores that allow passive diffusion of small molecules across the outer membrane.

    Polypeptides: Outer membrane porin CSynonyms: Outer membrane protein C, Outer membrane protein 1B
  3. Target

    Myristoylated alanine-rich C-kinase substrate

    go.drugbank.com/bio_entities/BE0012891
    TargetHumans

    protein docking to membranes (PubMed:23704996, PubMed:36009319). … Sequesters phosphatidylinositol 4,5-bisphosphate (PIP2) at lipid rafts in the plasma membrane of quiescent cells, an action reversed by protein kinase C, ultimately inhibiting exocytosis (PubMed:23704996

    Polypeptides: Myristoylated alanine-rich C-kinase substrateSynonyms: Protein kinase C substrate, 80 kDa protein, light chain, 80K-L protein
  4. Target

    Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

    go.drugbank.com/bio_entities/BE0002326
    TargetHumans

    PP2A is the major phosphatase for microtubule-associated proteins (MAPs) (PubMed:22613722). … Mediates dephosphorylation of WEE1, preventing its ubiquitin-mediated proteolysis, increasing WEE1 protein levels, and promoting the G2/M checkpoint (PubMed:33108758).

    Polypeptides: Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoformSynonyms: Replication protein C, RP-C
  5. Target

    Serine/threonine-protein kinase N2

    go.drugbank.com/bio_entities/BE0009521
    TargetHumans

    PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. … Mediates Rho protein-induced transcriptional activation via the c-fos serum response factor (SRF). Involved in the negative regulation of ciliogenesis (PubMed:27104747)

    Polypeptides: Serine/threonine-protein kinase N2Synonyms: Protein kinase C-like 2, Protein-kinase C-related kinase 2
  6. Target

    Nuclear migration protein nudC

    go.drugbank.com/bio_entities/BE0009030
    TargetHumans

    Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis (PubMed:12679384, PubMed:12852857, PubMed:25789526). Necessary for cytokine...

    Polypeptides: Nuclear migration protein nudCSynonyms: Nuclear distribution protein C homolog
  7. Target

    Cytochrome b-c1 complex subunit 8

    go.drugbank.com/bio_entities/BE0003857
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c

    Synonyms: Ubiquinol-cytochrome c reductase complex 9.5 kDa protein, Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C
  8. Target

    14-3-3 protein zeta/delta

    go.drugbank.com/bio_entities/BE0001174
    TargetHumans

    Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways (PubMed:14578935, PubMed:15071501, PubMed:15644438, PubMed:16376338, PubMed:16959763,

    Polypeptides: 14-3-3 protein zeta/deltaSynonyms: Protein kinase C inhibitor protein 1
  9. Target

    Diacylglycerol acyltransferase/mycolyltransferase Ag85C

    go.drugbank.com/bio_entities/BE0001688
    TargetMycobacterium tuberculosis

    The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria to fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine

    Synonyms: Fibronectin-binding protein C, Fbps C
  10. Target

    14-3-3 protein beta/alpha

    go.drugbank.com/bio_entities/BE0008974
    TargetHumans

    Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.

    Polypeptides: 14-3-3 protein beta/alphaSynonyms: Protein kinase C inhibitor protein 1, Protein 1054