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Displaying results 3601 - 3610 of 10000 in total
  1. Pathway

    Simvastatin Action Pathway

    smpdb.ca/view/SMP0000082
    Drug action

    contributes to ≤ 20% of its metabolism. … Cytochrome P450 (CYP) enzymes, CYP3A4, CYP3A5, and CYP2C8, have been implicated in this activation step; CYP3A4/5 are responsible for ≥ 80% of simvastatin metabolism while CYP2C8 (not shown in pathway)

    Drugs: Cholecalciferol · ATP · Simvastatin · Magnesium cation · Iron · Dimethylallyl Diphosphate +9 more
  2. Drug

    Saquinavir

    go.drugbank.com/drugs/DB01232
    ApprovedInvestigational

    Saquinavir is an HIV-1 protease inhibitor used in combination with [ritonavir] and other antiretrovirals for the treatment of human immunodeficiency virus-1 (HIV-1) infection. … In 1995 it became the first protease inhibitor approved by the FDA, followed shortly by ritonavir in 1996, and remains in clinical use today due to a relatively benign adverse effect profile as compared

    Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein inducersProducts: SAQUINAVIR 500 MG TABLETAS., SAQUINAVIR 500 MG TABLETA RECUBIERTA
  3. Drug

    Cloperastine

    go.drugbank.com/drugs/DB09002
    Investigational

    Cloperastine is a cough suppressant that acts on the central nervous system.

    Categories: Heterocyclic Compounds, 1-RingProducts: FENTUS 708 MG/100 ML ORAL SÜSPANSİYON, 200 ML, FENTUS 708 MG/100 ML ORAL SÜSPANSİYON, 100 ML
  4. Drug

    Octisalate

    go.drugbank.com/drugs/DB11062
    Approved

    Octyl salicylate appears to have a good safety profile. It covers wavelength in the range 295-315 nm, peak at 307-310 nm. It is an ester of salicylic acid and 2-ethylhexanol. … It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen.

    Mixtures: Avobenzone 3% Homosalate 10% Octisalate 5% Octocrylene 10%, Mv Body Defense SPF 20Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Measles virus vaccine live attenuated

    go.drugbank.com/drugs/DB10315
    ApprovedInvestigational

    Measles virus vaccine live attenuated is a live virus vaccine for simultaneous vaccination against measles, which is a common childhood disease.

    Mixtures: TRESIVAC 0,5 ML SC ENJEKSIYONLUK ÇÖZELTI IÇIN LIYOFILIZE TOZ IÇEREN FLAKON, 10 ADET, SII MEASLES,MUMPS & RUBELLA VACCINE LIVE ATTENUATED (FREEZE-DRIED) 10 DOSESSynonyms: Measles virus live antigen, A
  6. Indication

    Post-essential Thrombocythemia Myelofibrosis (Post-ET MF)

    go.drugbank.com/conditions/DBCOND0069581
    Drugs: Ruxolitinib
    Synonyms: Post ET MF, Post-ET MF
  7. Drug

    Castor oil

    go.drugbank.com/drugs/DB11113
    ApprovedNutraceuticalVet approved

    It also consists up to 4% linoleic, 3% oleic, 1% stearic, and less than 1% linolenic fatty acids [A31170]. … Castor oil is a rich source of [DB02955], which represents up to 90% of the total castor oil content.

    Mixtures: Polylab Surgical Spirit 98.8% v/v, HydroGold 9Products: RICIMENT 120 ML EMULSIYON, RICILAKS 60 ML EMULSIYON
  8. Drug

    Selpercatinib

    go.drugbank.com/drugs/DB15685
    ApprovedInvestigational

    Selpercatinib is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes. … [A202055, A202052, L13604] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers.

    Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingSynonyms: 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile
  9. Drug

    Bromelains

    go.drugbank.com/drugs/DB13281
    ApprovedInvestigational

    It is considered as a safe food supplement. … Bromelain is a protease enzyme derived from the stems of pineapples that is composed of a mixture of different thiol endopeptidases and other components like phosphatase, glucosidase, peroxidase, cellulase

    Mixtures: BIOGROW® VITE, PLASIL®ENZIMATICOProducts: Bromelain Pineapple Enzyme 50 Mg Nu Life, Bromelain 250
  10. Target

    Potassium channel subfamily K member 10

    go.drugbank.com/bio_entities/BE0013513
    TargetHumans

    K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens t...

    Polypeptides: Potassium channel subfamily K member 10