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Viral Sepsis
smpdb.ca/view/SMP0125490DiseaseViral sepsis begins when viral coat proteins activate the Toll-like receptors TLR4 and TLR2 on the membranes of macrophages, T-cells and dendritic cells. In addition to this protein activation, the viral DNA (or RNA if it is an RNA virus...
Tyrosinemia, Transient, of the Newborn
smpdb.ca/view/SMP0125592DiseaseThe inhibition is reversible by removal of excess substrate and by reducing agents such as ascorbic acid, 2, 6-dichiorophenolindophenol, and a number of hydroquinone and phenylenediamine compounds.
Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Aspartic acid · Tyrosine · Glutamic acid +20 moreCorticosterone Methyl Oxidase I Deficiency (CMO I)
smpdb.ca/view/SMP0125801DiseaseCorticosterone methyloxidase type I (CMO-I) deficiency, also known as 18-hydroxylase deficiency or aldosterone deficiency among other names, is a genetic disorder that is autosomally linked and caused by a defective CYP11B2 gene. This ge...
Desoximetasone Action Pathway
smpdb.ca/view/SMP0126224Drug actionDesoximetasone, also known as Desoxi or Topicort, is a topical anti-inflammatory glucocorticoid used to treat corticosteroid-responsive dermatoses. Desoximetasone is a selective glucocorticoid receptor agonist. By binding to the glucocor...