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Displaying results 4221 - 4230 of 10000 in total
  1. Target

    Glucosamine-6-phosphate deaminase 1

    go.drugbank.com/bio_entities/BE0001752
    TargetBacillus subtilis (strain 168)

    Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.

    Polypeptides: Glucosamine-6-phosphate deaminase 1Synonyms: Glucosamine-6-phosphate isomerase 1
  2. Target

    Protein-glutamine gamma-glutamyltransferase 6

    go.drugbank.com/bio_entities/BE0002239
    EnzymeHumans

    Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins

    Polypeptides: Protein-glutamine gamma-glutamyltransferase 6Synonyms: TGase-6, Transglutaminase-6
  3. Target

    rRNA adenine N-6-methyltransferase

    go.drugbank.com/bio_entities/BE0002516
    TargetBacillus subtilis

    This protein produces a dimethylation of the adenine residue at position 2085 in 23S rRNA, resulting in reduced affinity between ribosomes and macrolide-lincosamide-streptogramin B antibiotics.

    Polypeptides: rRNA adenine N-6-methyltransferaseFunction: 23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity
  4. Target

    Programmed cell death protein 6

    go.drugbank.com/bio_entities/BE0005812
    TargetHumans

    Calcium sensor that plays a key role in processes such as endoplasmic reticulum (ER)-Golgi vesicular transport, endosomal biogenesis or membrane repair. Acts as an adapter that bridges unrelated proteins or stabilizes weak protein-protei...

    Polypeptides: Programmed cell death protein 6
  5. Target

    Ephrin type-A receptor 6

    go.drugbank.com/bio_entities/BE0009439
    TargetHumans

    Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the rece...

    Polypeptides: Ephrin type-A receptor 6
  6. Target

    Interleukin-6 receptor subunit beta

    go.drugbank.com/bio_entities/BE0010013
    TargetHumans

    Engages site 2 of CNTF, CLCF1, LIF, and IL-6, and site 3 of IL27 and IL6 (PubMed:36930708). … In contrast, binding of other IL-6 family cytokines can result in the formation of a IL6ST/gp130 heterodimer with another signal-transducing receptor, such as LIFR or OSMR (PubMed:1542794, PubMed:39532904

    Polypeptides: Interleukin-6 receptor subunit betaSynonyms: IL-6 receptor subunit beta, Interleukin-6 signal transducer
  7. Target

    TNF receptor-associated factor 6

    go.drugbank.com/bio_entities/BE0021309
    TargetHumans

    E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as ECSIT, IKBKG, IRAK1, AKT1 and AKT2 (PubMed:11057907, PubMed:18347055, PubMed:1946591...

    Polypeptides: TNF receptor-associated factor 6
  8. Target

    G protein-coupled receptor 6

    go.drugbank.com/bio_entities/BE0021832
    TargetHumans

    Constitutively active G protein-coupled receptor that maintains high cAMP levels and contributes to several processes including neuronal development, through activation of intracellular signaling pathways via G(s). May be activated by li...

    Polypeptides: G protein-coupled receptor 6
  9. Drug

    Anastrozole

    go.drugbank.com/drugs/DB01217
    ApprovedInvestigational

    Anastrozole is a non-steroidal aromatase inhibitor (AI), similar to [letrozole], used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer … [L8863] Anastrozole is also related to [exemestane], a steroidal AI, but its non-steroidal nature provides stark advantages including a lack of steroid-associated adverse effects such as weight gain and

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
  10. Drug

    Sugammadex

    go.drugbank.com/drugs/DB06206
    ApprovedInvestigational

    Sugammadex provides a new treatment option to reverse the effects of those medications and possibly help patients recover sooner post-surgery. … Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery.

    Categories: Compounds used in a research, industrial, or household settingProducts: SUGAMMADEX SUN, BRIDION® 200 MG/2 ML SOLUCIÓN PARA INYECCIÓN