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Displaying results 431 - 440 of 10000 in total
  1. Drug

    Ropinirole

    go.drugbank.com/drugs/DB00268
    ApprovedInvestigational

    Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], [A174547]. … In 2008, the extended-release capsules of ropinirole were approved, allowing for less frequent dosing, therefore increased compliance, and offering a similar side effect profile and efficacy to previous

    Products: REQUIP 1.0MG, REQUIP 1MG
  2. Drug

    Lenalidomide

    go.drugbank.com/drugs/DB00480
    ApprovedInvestigational

    [A228708] Available as oral capsules, lenalidomide is approved by the FDA and EU for the treatment of multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, follicular lymphoma, and marginal … [L16028] Due to severe teratogenicity, pregnancy must be excluded before the start of treatment and patients must enroll in the lenalidomide Risk Evaluation and Mitigation Strategy (REMS) program to ensure

    Categories: Antineoplastic and Immunomodulating AgentsProducts: CIFEROL® 10MG, LENLI CAPSULES 10MG
  3. Drug

    Selenium Sulfide

    go.drugbank.com/drugs/DB00971
    Approved

    Selenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. … Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent

    Mixtures: Clease and TreatProducts: Selsun Blue Normal to Oily, Head and Shoulders Itch
  4. Drug

    Bisacodyl

    go.drugbank.com/drugs/DB09020
    ApprovedInvestigational

    [A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300] … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).

    Mixtures: HalfLytely and Bisacodyl, HalfLytely and BisacodylCategories: Alimentary Tract and Metabolism
  5. Drug

    Povidone-iodine

    go.drugbank.com/drugs/DB06812
    ApprovedInvestigational

    This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski. … Povidone-iodine is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. It contains from 9.0% to 12.0% available iodine, calculated on a dry basis.

    Mixtures: Physician EZ Use Joint Tunnel and Trigger Kit, JTT Physicians Joint, Tunnel and TriggerCategories: Antiseptics and Disinfectants, Genito Urinary System and Sex Hormones
  6. Drug

    Estriol

    go.drugbank.com/drugs/DB04573
    ApprovedInvestigationalVet approved

    Though estriol is used as part of the primarily North American phenomenon of bioidentical hormone replacement therapy, it is not approved for use by the FDA or Health Canada. … It has also been approved and marketed throughout Europe and Asia for approximately 40 years for the treatment of post-menopausal hot flashes.

    Categories: Genito Urinary System and Sex Hormones, Natural and Semisynthetic Estrogens, PlainProducts: OEKOLP TABLETTEN 2MG, ESTRIOL 2MG FEM JENAPHARM
  7. Pathway

    Valine, Leucine, and Isoleucine Degradation

    smpdb.ca/view/SMP0000032
    Metabolic

    These acyl-CoA’s undergo dehydrogenation, catalyzed by three different but related enzymes, and the breakdown pathways then diverge. … and acetyl-CoA) and glucose (succinyl-CoA).

    Drugs: Pyridoxal phosphate · Biotin · Succinic acid · Glutamic acid · Pyridoxal · Leucine +10 more
  8. Pathway

    Threonine and 2-Oxobutanoate Degradation

    smpdb.ca/view/SMP0000452
    Metabolic

    While no 2-oxo acid dehydrogenase complex is specific to 2-oxobutanoate, numerous complexes can catalyze its reaction. … 2-oxobutanoate, also known as 2-Ketobutyric acid, is a 2-keto acid that is commonly produced in the metabolism of amino acids such as methionine and threonine.

    Drugs: Pyridoxal phosphate · Biotin · Threonine · NADH · ATP · Flavin adenine dinucleotide +1 more
  9. Drug

    Atracurium besylate

    go.drugbank.com/drugs/DB00732
    Approved

    Its lack of significant cardiovascular effects and its lack of dependence on good kidney function for elimination provide clinical advantage over alternate non-depolarizing neuromuscular blocking agents … A non-depolarizing neuromuscular blocking agent with short duration of action.

    Products: TRACRIUM INJECTION 25MG/2.5ML, Atracurium-hameln Injection 10mg/ml
  10. Drug

    Phenazopyridine

    go.drugbank.com/drugs/DB01438
    ApprovedInvestigational

    Ingestion of phenazopyridine is found to change the appearance of the urine by imparting an orange or red color, as it is considered an azo dye.[L7829] … In the USA, this drug was previously marked by Roche but has been discontinued by the FDA.[L7832] It is still used in various parts of the world.

    Mixtures: Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and ButabarbitalCategories: Antipruritics and Local Anesthetics, Genito Urinary System and Sex Hormones