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S-Hydroxycysteine
go.drugbank.com/drugs/DB01915ExperimentalIt targets the proteins subtilisin BPN', glutathione S-transferase A1, glutathione S-transferase p, myelin P2 protein, and complement c3.
Fluindione
go.drugbank.com/drugs/DB13136ApprovedWithdrawnFluindione has been investigated for the treatment of Blood Coagulation Disorders. … Fluindione is under investigation for the treatment of Venous Thrombosis, Pulmonary Embolism, Permanent Atrial Fibrillation, and Anticoagulating Treatment on a Duration at Least 12-month-old Superior.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesND1251
go.drugbank.com/drugs/DB05132ExperimentalND1251 may also have applications in other disorders, such as Alzheimer's disease, mild cognitive impairment, multiple sclerosis and certain respiratory diseases. … ND1251 is an orally active phosphodiesterase-4 (PDE4) inhibitor, a mechanism clinically proven to play a role in alleviating symptoms of depression.
Acepromazine
go.drugbank.com/drugs/DB01614InvestigationalVet approvedAcepromazine is one of the phenothiazine derivative psychotropic drugs, used little in humans, however frequently in animals as a sedative and antiemetic.
Categories: Adrenergic alpha-1 Receptor Antagonists, Dopamine D2 Receptor AntagonistsMelperone
go.drugbank.com/drugs/DB09224InvestigationalMelperone has been used for a span of greater than 30 years in the European Union [L1316]. … Melperone is an atypical antipsychotic of the butyrophenone chemical class, making it structurally related to the typical antipsychotic haloperidol.
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsCatridecacog
go.drugbank.com/drugs/DB09310ApprovedFor people with congenital deficiency or mutation of Factor XIII, a rare bleeding disorder, exogenous replacement of this key coagulation factor is essential for management and prevention of bleeding episodes … In patients with congenital factor XIII A-subunit deficiency, this product (marketed as Tretten) is indicated for the routine prophylaxis of bleeding.
Amiodarone Action Pathway
smpdb.ca/view/SMP0000665Drug actionAmiodarone, trade name Cordarone and Nexterone, is an antianginal and a class III antiarrhythmic drug prescribed to treat irregular heart rhythms. The drug inhibits Na,K-activated myocardial adenosine triphosphatase, calcium and potassiu...
Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2Plitidepsin
go.drugbank.com/drugs/DB04977InvestigationalAplidine is also of interest as a potential treatment for some leukemias.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesVerticillium albo-atrum
go.drugbank.com/drugs/DB10850ApprovedVerticillium albo-atrum is a fungus which can provoke allergic reactions. Verticillium albo-atrum extract is used in allergenic testing.