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Displaying results 41 - 50 of 2725 in total
  1. Target

    Protein-methionine-sulfoxide reductase catalytic subunit MsrP

    go.drugbank.com/bio_entities/BE0001990
    TargetEscherichia coli O157:H7

    The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide. … Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.

    Polypeptides: Protein-methionine-sulfoxide reductase catalytic subunit MsrP
  2. Target

    Methionine-R-sulfoxide reductase B2, mitochondrial

    go.drugbank.com/bio_entities/BE0000432
    EnzymeHumans

    Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. … While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue

    Polypeptides: Methionine-R-sulfoxide reductase B2, mitochondrial
  3. Target

    5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

    go.drugbank.com/bio_entities/BE0001620
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

    Synonyms: Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme
  4. Target

    S-adenosylmethionine synthase isoform type-2

    go.drugbank.com/bio_entities/BE0000304
    TargetEnzymeHumans

    Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

    Synonyms: Methionine adenosyltransferase 2, Methionine adenosyltransferase II
  5. Target

    S-adenosylmethionine synthase

    go.drugbank.com/bio_entities/BE0001499
    TargetShigella flexneri

    Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.

    Synonyms: Methionine adenosyltransferase
  6. Target

    S-adenosylmethionine synthase isoform type-1

    go.drugbank.com/bio_entities/BE0000407
    TargetEnzymeHumans

    Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

    Synonyms: Methionine adenosyltransferase 1, Methionine adenosyltransferase I/III
  7. Target

    Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial

    go.drugbank.com/bio_entities/BE0000727
    TargetEnzymeHumans

    Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine.

    Synonyms: Methionine--glyoxylate transaminase AADAT
  8. Pathway

    Methionine Metabolism

    smpdb.ca/view/SMP0000033
    Metabolic

    Methionine metabolism is a process that is necessary for humans. Methionine metabolism in mammals happens within two pathways, a methionine cycle and a transsulfuration sequence. … When there is a lack of methionine, there is a decrease in the production of SAM, which limits cystathionine synthase activity.

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 more
    Enzymes: Methionine synthase, Methionine--tRNA ligase, cytoplasmic
  9. Pathway

    Methionine Adenosyltransferase Deficiency

    smpdb.ca/view/SMP0000221
    Disease

    MAT dificiency is characterized by increased homocysteine and methionine levels in plasma; and accumulation of methionine in urine. Symptoms include dystonia, mental retardation and unusual odor. … MAT catalyzes the formation of adenosylmethionine from methionine and ATP. Adenosylmethionine is an important methyl donor in most transmethylation reactions.

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 more
    Enzymes: Methionine synthase, Methionine--tRNA ligase, cytoplasmic
  10. Pathway

    Methionine Adenosyltransferase Deficiency

    smpdb.ca/view/SMP0125683
    Disease

    MAT dificiency is characterized by increased homocysteine and methionine levels in plasma; and accumulation of methionine in urine. Symptoms include dystonia, mental retardation and unusual odor. … MAT catalyzes the formation of adenosylmethionine from methionine and ATP. Adenosylmethionine is an important methyl donor in most transmethylation reactions.

    Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 more
    Enzymes: Methionine synthase, Methionine--tRNA ligase, cytoplasmic