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Pentazocine Action Pathway
smpdb.ca/view/SMP0000686Drug actionPentazocine (also known as Talwin) is a type of medication that can relieve moderate to severe pain. Pentazocine can bind to mu-type opioid receptor and kappa-type opioid receptor on neuron of central nerves system (CNS). Binding of pent...
Dopamine Action Pathway
smpdb.ca/view/SMP0125137Drug actionIn the neuron, it is catalyzed by Dopamine beta-hydroxylase to synthesize norepinephrine. Norepinephrine is stored in synaptic storage sites where norepinephrine was already being stored. … When the neuron is depolarized, this accumulation of norepinephrine is released into the synapse.
Dopamine Action Pathway
smpdb.ca/view/SMP0127069PhysiologicalIn the neuron, it is catalyzed by Dopamine beta-hydroxylase to synthesize norepinephrine. Norepinephrine is stored in synaptic storage sites where norepinephrine was already being stored. … When the neuron is depolarized, this accumulation of norepinephrine is released into the synapse.
Bupivacaine Action Pathway
smpdb.ca/view/SMP0000393Drug actionBupivacaine exerts its local anaesthetic effect by blocking voltage-gated sodium channels in peripheral neurons. Bupivacaine diffuses across the neuronal plasma membrane in its uncharged base form. Once inside the cytoplasm, it is proton...
Chloroprocaine Action Pathway
smpdb.ca/view/SMP0000394Drug actionChloroprocaine exerts its local anaesthetic effect by blocking voltage-gated sodium channels in peripheral neurons. Chloroprocaine diffuses across the neuronal plasma membrane in its uncharged base form. Once inside the cytoplasm, it is ...
Proparacaine Action Pathway
smpdb.ca/view/SMP0000403Drug actionProparacaine exerts its local anaesthetic effect by blocking voltage-gated sodium channels in peripheral neurons. Proparacaine diffuses across the neuronal plasma membrane in its uncharged base form. Once inside the cytoplasm, it is prot...
Oxymorphone Action Pathway
smpdb.ca/view/SMP0000412Drug actionOxymorphone (also known as Numorphan) is analgesic that can bind to mu-type opioid receptor to activate associated G-protein in the sensory neurons of central nervous system (CNS), which will reduce the level of intracellular cAMP by inh...
Carfentanil Action Pathway
smpdb.ca/view/SMP0000414Drug actionCarfentanil (also known as carfentanyl or Wildnil) is analgesic that can bind to mu-type opioid receptor to activate associated G-protein in the sensory neurons of central nervous system (CNS), which will reduce the level of intracellula...
Remifentanil Action Pathway
smpdb.ca/view/SMP0000416Drug actionRemifentanil is a pharmacologically-active, synthetic, small molecule derived from fentanyl and belongs to a class of drugs called opioids. Opioids are therapeutically employed to achieve analgesia. Remifentanial’s rapid mechanism of act...
Diphenoxylate Action Pathway
smpdb.ca/view/SMP0000675Drug actionDiphenoxylate (also known as Difenossilato or Lomotil) is analgesic that can bind to mu-type opioid receptor to activate associated G-protein in the sensory neurons of central nervous system (CNS), which will reduce the level of intracel...