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2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
go.drugbank.com/bio_entities/BE0001617TargetThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate
Polypeptides: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthaseFunction: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
go.drugbank.com/bio_entities/BE0001661TargetEscherichia coli (strain K12)Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
Polypeptides: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferaseFunction: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
go.drugbank.com/bio_entities/BE0001839TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
Polypeptides: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferaseFunction: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activityActin-related protein 2/3 complex subunit 1B
go.drugbank.com/bio_entities/BE0004249TargetHumansComponent of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:11741539, PubMed:9230079). The Arp2/3 complex mediates the formation of branched act...
Polypeptides: Actin-related protein 2/3 complex subunit 1BActin-related protein 2/3 complex subunit 3
go.drugbank.com/bio_entities/BE0004253TargetHumansComponent of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in th...
Polypeptides: Actin-related protein 2/3 complex subunit 3Small conductance calcium-activated potassium channel protein 2
go.drugbank.com/bio_entities/BE0004426TargetHumansSmall conductance calcium-activated potassium channel that mediates the voltage-independent transmembrane transfer of potassium across the cell membrane through a constitutive interaction with calmodulin which binds the intracellular cal...
Polypeptides: Small conductance calcium-activated potassium channel protein 2Synonyms: SKCa 2Potassium voltage-gated channel subfamily A member 2
go.drugbank.com/bio_entities/BE0004715TargetHumansVoltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the cardiovascular system. Prevents aberrant action potential firi...
Polypeptides: Potassium voltage-gated channel subfamily A member 2Solute carrier family 52, riboflavin transporter, member 2
go.drugbank.com/bio_entities/BE0004841TargetTransporterHumansPlasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism (PubMed:2046314...
Polypeptides: Solute carrier family 52, riboflavin transporter, member 2Myosin light chain kinase 2, skeletal/cardiac muscle
go.drugbank.com/bio_entities/BE0004946TargetHumansCa(2+)/calmodulin-dependent kinase that phosphorylates the regulatory light chain (RLC) of sarcomeric myosin in skeletal and cardiac muscle. … thick filament backbone toward actin-containing thin filaments, increasing the probability of cross-bridge entry into force-generating states and thereby potentiating contractile force at submaximal Ca(2+
Polypeptides: Myosin light chain kinase 2, skeletal/cardiac muscleCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1
go.drugbank.com/bio_entities/BE0008997TargetHumansS-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs.
Polypeptides: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1Synonyms: Cap1 2'O-ribose methyltransferase 1, FtsJ methyltransferase domain-containing protein 2