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Chloramphenicol succinate
go.drugbank.com/drugs/DB07565ApprovedChloramphenicol succinate is an ester prodrug of [chloramphenicol].[A192987] Chloramphenicol is a bacteriostatic antibiotic. … [A204065] Use of chloramphenicol succinate and chloramphenicol has decreased due to the risk of potentially fatal blood dyscrasias.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein substratesProducts: SUMICLORAN ® 1 G INYECTABLE, GEMYSETIN SÜKSİNAT 1G I.M./ I.V. ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN LİYOFİLİZE TOZ, 1 FLAKONOctisalate
go.drugbank.com/drugs/DB11062ApprovedIt covers wavelength in the range 295-315 nm, peak at 307-310 nm. It is an ester of salicylic acid and 2-ethylhexanol. … Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen.
Synonyms: 2-Ethylhexyl 2-hydroxybenzoate, 2-Ethylhexyl salicylateMixtures: Snail Essential EX Wrinkle Soluti on Sun Crea m, Gold Bond Ultimate 5-in-1 FaceDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
go.drugbank.com/bio_entities/BE0003558TargetHumansCatalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively (PubMed:10725373, PubMed:10906126, PubMed:11050148)
Polypeptides: Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AFunction: 3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activityLactose
go.drugbank.com/drugs/DB04465ApprovedInvestigationalWithdrawnA disaccharide of glucose and galactose in human and cow milk. It is used in pharmacy for tablets, in medicine as a nutrient, and in industry.
Mixtures: SYNTHROID® 112 MCG TABLETAS, SERECOR® FORTE DPI 100Categories: Compounds used in a research, industrial, or household settingtRNA (cytidine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase
go.drugbank.com/bio_entities/BE0002518TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
Polypeptides: tRNA (cytidine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferaseHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A
go.drugbank.com/bio_entities/BE0003134TargetHumansSpecifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity...
Polypeptides: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9AFunction: 3',5'-cyclic-AMP phosphodiesterase activityLeucine-rich repeat-containing G protein-coupled receptor 5
go.drugbank.com/bio_entities/BE0010835TargetHumansReceptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with ph...
Polypeptides: Leucine-rich repeat-containing G protein-coupled receptor 5Transient receptor potential cation channel subfamily M member 5
go.drugbank.com/bio_entities/BE0020643TargetHumansMonovalent cation-selective ion channel activated by intracellular Ca(2+) in a voltage- and temperature-dependent manner (PubMed:14634208). Mediates the transport of Na(+), K(+) and Cs(+) ions equally well (PubMed:14634208). Activated di...
Polypeptides: Transient receptor potential cation channel subfamily M member 5Synonyms: MLSN1- and TRP-related gene 1 protein, LTrpC-5Phenylbutazone
go.drugbank.com/drugs/DB00812ApprovedVet approvedWithdrawnA drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis. … It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication).
Categories: Heterocyclic Compounds, 1-Ring, Non COX-2 selective NSAIDSSynonyms: 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine, 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedioneKininogen-1
go.drugbank.com/bio_entities/BE0001017TargetHumansKininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; HMW-kininogen inhibits the thrombin- and plasmin-in...
Polypeptides: Kininogen-1