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Voltage-dependent L-type calcium channel subunit alpha-1C
go.drugbank.com/bio_entities/BE0000430TargetHumansMediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm (By similarity). Plays an important role in excitation-contraction coupling in the heart. … Required for normal contraction of smooth muscle cells in blood vessels and in the intestine.
Polypeptides: Voltage-dependent L-type calcium channel subunit alpha-1CSynonyms: Voltage-gated calcium channel subunit alpha Cav1.2, Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscleVoltage-dependent N-type calcium channel subunit alpha-1B
go.drugbank.com/bio_entities/BE0002226TargetHumansVoltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone … or neurotransmitter release, gene expression, cell motility, cell division and cell death.
Polypeptides: Voltage-dependent N-type calcium channel subunit alpha-1BSynonyms: Brain calcium channel III, Voltage-gated calcium channel subunit alpha Cav2.2Voltage-dependent L-type calcium channel subunit beta-2
go.drugbank.com/bio_entities/BE0002354TargetHumansBeta subunit of voltage-dependent calcium channels which contributes to the function of the calcium channel by increasing peak calcium current (By similarity). … Plays a role in shifting voltage dependencies of activation and inactivation of the channel (By similarity). May modulate G protein inhibition (By similarity).
Polypeptides: Voltage-dependent L-type calcium channel subunit beta-2Synonyms: Calcium channel voltage-dependent subunit beta 2Voltage-dependent L-type calcium channel subunit alpha-1F
go.drugbank.com/bio_entities/BE0002357TargetHumansVoltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone … Activates at more negative voltages and does not undergo calcium-dependent inactivation (CDI), due to incoming calcium ions, during depolarization
Polypeptides: Voltage-dependent L-type calcium channel subunit alpha-1FSynonyms: Voltage-gated calcium channel subunit alpha Cav1.4Voltage-dependent L-type calcium channel subunit beta-3
go.drugbank.com/bio_entities/BE0002358TargetHumansIncreases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity). … Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity)
Polypeptides: Voltage-dependent L-type calcium channel subunit beta-3Synonyms: Calcium channel voltage-dependent subunit beta 3Voltage-dependent calcium channel subunit alpha-2/delta-3
go.drugbank.com/bio_entities/BE0003563TargetHumansThe alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. … Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) but not T-type (CACNA1G) (By similarity)
Polypeptides: Voltage-dependent calcium channel subunit alpha-2/delta-3Synonyms: Voltage-gated calcium channel subunit alpha-2/delta-3Calcium/calmodulin-dependent protein kinase type II subunit alpha
go.drugbank.com/bio_entities/BE0004076TargetHumansCalcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in various processes, such as synaptic plasticity, neurotransmitter … release and long-term potentiation (PubMed:14722083).
Polypeptides: Calcium/calmodulin-dependent protein kinase type II subunit alphaCalcium/calmodulin-dependent protein kinase type II subunit gamma
go.drugbank.com/bio_entities/BE0004384TargetHumansCalcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplasmic reticulum Ca(2+) transport in skeletal muscle … and may function in dendritic spine and synapse formation and neuronal plasticity (PubMed:16690701).
Polypeptides: Calcium/calmodulin-dependent protein kinase type II subunit gammaVoltage-dependent T-type calcium channel subunit alpha-1G
go.drugbank.com/bio_entities/BE0000483TargetHumansVoltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone … T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle.
Polypeptides: Voltage-dependent T-type calcium channel subunit alpha-1GSynonyms: Voltage-gated calcium channel subunit alpha Cav3.1Voltage-dependent calcium channel subunit alpha-2/delta-1
go.drugbank.com/bio_entities/BE0000691TargetHumansThe alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel (PubMed:35293990). … Plays an important role in excitation-contraction coupling (By similarity)
Polypeptides: Voltage-dependent calcium channel subunit alpha-2/delta-1Synonyms: Voltage-gated calcium channel subunit alpha-2/delta-1