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Displaying results 61 - 70 of 432 in total
  1. Drug

    Berahyaluronidase alfa

    go.drugbank.com/drugs/DB22790
    ApprovedInvestigational

    Berahyaluronidase alfa is a recombinant variant of human hyaluronidase designed to enhance dispersion and permeation of subcutaneously co-administered drugs. It is used in a fixed-dose combination with pembrolizumab for subcutaneous inje...

  2. Indication

    Lipid-Lowering Therapy

    go.drugbank.com/conditions/DBCOND0112500
    Drugs: Alirocumab · Atorvastatin · Bempedoic acid · Evinacumab · Ezetimibe · Lomitapide +2 more
  3. Drug

    Ethotoin

    go.drugbank.com/drugs/DB00754
    Approved

    Ethotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression. The mechanism of action is probably very similar to that of phenytoin. The latter d...

  4. Indication

    High Cholesterol

    go.drugbank.com/conditions/DBCOND0037835
    Drugs: Atorvastatin · Enlicitide · Inclisiran · Lerodalcibep · Niacin · Pravastatin +3 more
  5. Drug

    Plasminogen

    go.drugbank.com/drugs/DB16701
    ApprovedInvestigational

    Plasminogen is a pro-enzyme (i.e. a zymogen) which is cleaved to form plasmin - also known as fibrinolysin - as part of the fibrinolytic pathway that breaks down fibrin blood clots. This pathway is activated when a clot is no longer need...

  6. Indication

    Homozygous Familial Hypercholesterolaemia (HoFH)

    go.drugbank.com/conditions/DBCOND0135612
    Drugs: Alirocumab · Amlodipine · Atorvastatin · Evinacumab · Evolocumab · Ezetimibe +4 more
  7. Drug

    Iophendylate

    go.drugbank.com/drugs/DB01187
    Approved

    Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231). Iophendylate, which was never shown to be safe, was initially...

  8. Indication

    Prophylaxis of cardiovascular event

    go.drugbank.com/conditions/DBCOND0023400
    Drugs: Acetylsalicylic acid · Bisoprolol · Clopidogrel · Dalteparin · Lisinopril · Prasugrel +4 more
  9. Drug

    Amifampridine

    go.drugbank.com/drugs/DB11640
    Approved

    Amifampridine, or 3,4-diaminopyridine (3,4-DAP), is a quaternary ammonium compound that blocks presynaptic potassium channels, and subsequently prolongs the action potential and increases presynaptic calcium concentrations . It was first...

  10. Drug

    Niraparib

    go.drugbank.com/drugs/DB11793
    ApprovedInvestigational

    Niraparib is an orally active poly (ADP-ribose) polymerase (PARP) inhibitor. By blocking the enzymes responsible for DNA repair, niraparib induces cytotoxicity in cancer cells. Niraparib is selective towards PARP-1 and PARP-2. First appr...