High Cholesterol (DBCOND0037835)

Identifiers

Synonyms
High Blood Cholesterol Levels / High Blood Cholesterol Level / Hypercholesterolemia / Hypercholesterolaemia / High Blood Cholesterol / Elevated levels of cholesterol / Hypercholesteremia / High cholesterol / Hypercholesterolemia (disorder) / Hypercholesteraemia / Elevated cholesterol / Cholesterol total increased / Cholesterol levels raised / Cholesterol high / Cholesterol blood excessive / Cholesterol blood increased / Blood cholesterol increased

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Atorvastatin
An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Niacin
A B vitamin used to treat hypertriglyceridemia and pellagra.
Pravastatin
An HMG-CoA reductase inhibitor used to lower lipid levels and to reduce the risk of cardiovascular events, including myocardial infarction and stroke.
Rosuvastatin
An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Simvastatin
An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular events including myocardial infarction and stroke.
Tocopheryl nicotinate
A vitamin E supplement indicated in the treatment of high cholesterol and narrowing of peripheral arteries.
No drug targets
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05129891
A Research Study Looking at New Protein-based Tablets in Healthy Male Participantstreatment1completed
NCT00485095
The Effect of Plant Sterol Supplement on Blood CholesterolNo drug interventionstreatment4completed
NCT05362903
A Non-interventional Implementation Study to Evaluate Treatment With Inclisiran (Leqvio®) and Other Lipid Lowering Treatments in a Real-world SettingNo drug interventionsNot AvailableNot Availablerecruiting
NCT00005203
Genetics of Low Density Lipoprotein Subclasses in HypercholesterolemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT00109603
Effect of Tenofovir Disoproxil Fumarate on Lipid Levels in HIV Infected Adults on Stable Anti-HIV Drug TherapytreatmentNot Availablecompleted
NCT01279590
Study of the Safety and Tolerability Associated With PPD10558 Versus Atorvastatin in Patients Previously Intolerant to Statins Due to Statin-associated Myalgia (SAM)treatment2completed
NCT02587390
Effect of Gemcabene on the Pharmacokinetics of Simvastatin in Healthy Volunteersbasic_science1completed
NCT01317290
Supplementation of Alpha-linolenic Acid (ALA)-Rich Oil in HumansNo drug interventionsprevention0completed
NCT00092690
MK0653A (Ezetimibe (+) Simvastatin) Compared to an Approved Drug (Atorvastatin) for the Treatment of High Cholesterol (0653A-051)(COMPLETED)treatment3completed
NCT01370590
A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/20 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 20 mg Tablets in Participants With High Cholesterol (MK-0653C-185 AM1)treatment3completed
NCT02612090
The Cholesterol Lowering Effects of StrawberryNo drug interventionsbasic_scienceNot Availablecompleted
NCT03206164
HealthMatters@24/7 eLearning for People Supporting Adults With Intellectual and Developmental DisabilitiesNo drug interventionssupportive_careNot Availablecompleted
NCT00793364
Effect of Plant Stanol Ester-Containing Spread on Estimated Cardiovascular Risk in Comparison to Mediterranean DietNo drug interventionsprevention4completed
NCT02666664
Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk (CLEAR Harmony)treatment3completed
NCT00762164
Comparison of the Effect of Vytorin 10/80 Tablet Split Into 4 and Simvastatin 20 Milligrams on Low-density Lipoprotein (LDL) Cholesteroltreatment4completed
NCT00794664
Safety and Efficacy of Mipomersen in Patients With Severe Hypercholesterolemia on a Maximally Tolerated Lipid-Lowering Regimen and Who Are Not on Apheresistreatment3completed
NCT00004564
The Inhibition of Platelet Antiaggregating Activity of Clopidogrel by Atorvastatin Detected by Erythromycin Breath Test: a Metabolic Inhibition of Hepatic Cytochrome P450-3AtreatmentNot Availableunknown_status
NCT04673721
PROSPective Evaluation of Fortified Eggs Related to Improvement in The Biomarker Profile for Your HealthNo drug interventionsotherNot Availablecompleted
NCT04697121
Artichoke and Bergamot PhytosomeNo drug interventionstreatmentNot Availablecompleted
NCT03885921
Safety and Tolerability Study of Ezetimibe (SCH 058235/MK-0653) Plus Atorvastatin or Simvastatin in Homozygous Familial Hypercholesterolemia (P01417/MK-0653-019)treatment3completed
NCT00526721
Real-life EValuation Of High Dose RosUvastatin in High Risk Patients After TitraTIONNo drug interventionsNot AvailableNot Availablecompleted
NCT00163202
Comparative Atorvastatin Pleiotropic Effectstreatment4completed
NCT00844402
Safety and Efficacy of Long-Term Treatment With Atorvastatin in Patients With Primary Biliary Cirrhosistreatment3completed
NCT00129402
Effects of Ezetimibe With Simvastatin in the Therapy of Adolescents With HeFH (Study P02579)treatment3completed
NCT02304484
Open-label Extension (OLE) Study to Assess Safety and Efficacy of Evolocumabtreatment3completed
NCT01576484
Open-Label Extension of Study R727-CL-1003 (NCT01266876) to Evaluate the Long-Term Safety and Efficacy of Alirocumab (REGN727) in Participants With Heterozygous Familial Hypercholesterolemia (HeFH)treatment2completed
NCT01625884
Observational Study to Understand Patients' and Physicians' Attitudes to Statins in TurkeYNo drug interventionsNot AvailableNot Availablecompleted
NCT00276484
To Evaluate Ezetimibe Plus Atorvastatin Versus Atorvastatin in Patients With High Cholesterol Not Controlled on Atorvastatin 40 mg (0653-090)treatment3completed
NCT01856179
Supplementation of Land-based Stearidonic Acid (SDA)-Rich Oils in HumansNo drug interventionsprevention0completed
NCT01516879
Durable Effect of PCSK9 Antibody CompARed wiTh placEbo Studytreatment3completed
NCT01381679
Effect of Ezetimibe Treatment on Low-density Lipoprotein Cholesterol (LDL-C) Levels in Participants With Coronary Heart Disease (CHD) Already Treated With a Statin (MK-0653A-205 AM1)Not AvailableNot Availablecompleted
NCT05594979
Effects of 6 Weeks TOTUM-070 on Lipid Metabolism and Cardiovascular Health in Individuals at Increased Cardio-metabolic RiskNo drug interventionspreventionNot Availableterminated
NCT01288443
Efficacy and Safety Evaluation of Alirocumab (SAR236553/REGN727) in Patients With Primary Hypercholesterolemia on Stable Atorvastatin Therapytreatment2completed
NCT02857543
Plant-Based, American Heart Assoc. or Mediterranean Diets In 9-18 yo With BMI >95%, Cholesterol >169 and Their ParentsNo drug interventionspreventionNot Availablecompleted
NCT06504043
A Study on Evaluating the Safety of HST101 in Healthy Chinese ParticipantsNo drug interventionstreatment1not_yet_recruiting
NCT00067587
Metabolic Abnormalities in HIV Infected and Uninfected Young WomenNo drug interventionsNot AvailableNot Availablecompleted
NCT03550287
Evaluation of the Effect of a Shiitake Extract on Lipid Profile in Subjects With Moderate HyperlipidemiaNo drug interventionstreatment4completed
NCT00363233
The Potential Effects and Mechanisms of Flax Lignans on Type 2 Diabetes MellitusNo drug interventionstreatment2 / 3completed
NCT02497833
Retinoic Acid Supplementation and Subjects With HypercholesterolemiaNo drug interventionstreatment0completed
NCT00378833
Tolerability of MK0524A Versus Niacin Extended-Release (0524A-054)treatment3completed
NCT00074633
Evaluating "Health at Every Size"(HAES) as an Alternative Obesity Treatment ModelNo drug interventionstreatmentNot Availablecompleted
NCT00738933
Dietary Phytosterols and Human Aortic ValveNo drug interventionstreatmentNot Availableunknown_status
NCT01166633
Efficacy and Safety Study of Pitavastatin Versus Atorvastatin to Treat Hypercholesterolemiatreatment4completed
NCT00001154
Lipoprotein Metabolism in Normal Volunteers and Patients With High Levels of LipoproteinsNo drug interventionsNot AvailableNot Availablecompleted
NCT00466154
The Effect of Serum LDL Lowering on Aspirin ResistancetreatmentNot Availablecompleted
NCT01057654
A Study Comparing the Mechanisms of Action of Lifibrol and Pravastatinbasic_science3completed
NCT00267254
A Clinical Trial Comparing Torcetrapib/Atorvastatin To Simvastatin In Subjects With High Cholesterol.treatment3completed
NCT00440154
A Study Evaluating the Safety and Efficacy of AVE5530 (4 Weeks) in Patients With Mild to Moderate Hypercholesterolemiatreatment2completed
NCT01569854
Genetic Influence on Statin PharmacodynamicsNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01043354
TACTICS (Targeting Adherence to Cholesterol-lowering Therapy to Improve Control Study)No drug interventionspreventionNot Availablecompleted
NCT00221754
Pravastatin and Protease Inhibitors in HIV-Infected Patientstreatment2completed
NCT04760951
Effect of Totum-070 on Lipid Metabolism in Moderate Hypercholesterolemic SubjectsNo drug interventionspreventionNot Availablecompleted
NCT01243151
Safety And Tolerability Of Multiple Doses Of PF-04950615 (RN316) In Subjects With Hypercholesterolemiatreatment1completed
NCT01414751
Influence of Intervention Methodologies on Patient Choice of TherapyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00082251
Safety & Efficacy of a Combination Niacin ER/Simvastatin in Patients With Dyslipidemia: A Dose-Ranging Study - SEACOASTtreatment3completed
NCT01163851
Pharmacokinetic And Pharmacodynamic Study Of A Single-Dose Of PF-04950615 (RN316) In Combination With Atorvastatintreatment1completed
NCT00092651
A Study of MK0653A (Ezetimibe (+) Simvastatin) in Patients With Hypercholesterolemia (0653A-038)treatment3completed
NCT01070953
EZETROL® Re-examination Study (MK0653-175)(COMPLETED)No drug interventionsNot AvailableNot Availablecompleted
NCT06359353
Effect of Pitavastatin on Boneprevention4completed
NCT01730053
Study of Alirocumab (REGN727/SAR236553) added-on to Rosuvastatin Versus Other Lipid Modifying Treatments (LMT) (ODYSSEY OPTIONS II)treatment3completed
NCT01779453
A Study of the Safety, Pharmacokinetic Drug Interaction and Efficacy of ETC-1002 and Atorvastatin in Subjects With Hypercholesterolemiatreatment2completed
NCT04974853
Cholesterol Lowering Effect of Cardio-Complement, an Ayurveda FormulationNo drug interventionssupportive_careNot Availablecompleted
NCT06287177
Multicenter Study on the Evaluation of Adherence, Persistence and Efficacy of Treatment With Inclisiran in ItalyNot AvailableNot Availablerecruiting
NCT00794677
Effects of Ezetimibe on the Absorption of Oxidized Cholesterolbasic_science4completed
NCT00309777
Study to Compare the Efficacy and Safety of Pitavastatin and Simvastatintreatment3completed
NCT01744977
Cholesterol Medication Packaging StudyNo drug interventionshealth_services_researchNot Availablecompleted
NCT02374047
A 2-Part, Phase 1, Single and Multiple Ascending Dose Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of CAT-2054 in Healthy Subjectsother1completed
NCT00652847
Randomized Parallel Group Trial Of The Efficacy And Safety Of Ezetimibe With A Statin Versus Statin Dose Doubling In Patients With Persistent Primary Hypercholesterolemia (0653-152)(COMPLETED)treatment4completed
NCT00502047
Effect of the Plantago Ovata Husk on the Lipid Profile of Patients With HypercholesterolemiaNo drug interventionstreatment2 / 3completed
NCT05425745
Evaluate the Effect of Obicetrapib in Patients With HeFH on Top of Maximum Tolerated Lipid-Modifying Therapies.treatment3completed
NCT00653445
Compare the Safety & Efficacy of Rosuvastatin 40mg in Combination With Ezetimibe 10mgtreatment3completed
NCT06556745
Pharmacokinetics of Butyrate Tablet BKR-017Not AvailableNot Availablenot_yet_recruiting
NCT02741245
A Study of the Efficacy and Safety of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-832)treatment3completed
NCT00000598
Diet and Exercise for Elevated Risk (DEER)No drug interventionsprevention3completed
NCT00152698
Effect of Irbesartan on Endothelial Function of the Retinal Vasculature in Patients With Hypercholesterolemiatreatment3completed
NCT06065098
Church-based Health Intervention to Eliminate Racial Inequalities in Cardiovascular HealthNo drug interventionspreventionNot Availablerecruiting
NCT03929198
Translation of Pritikin Program to the CommunityNo drug interventionstreatmentNot Availablecompleted
NCT01564498
Effects of Purple Vegetables on Cardiovascular Disease (CVD) Risk FactorsNo drug interventionsprevention1unknown_status
NCT00421005
Fluvastatin After Heart Transplantationprevention4unknown_status
NCT01566305
Effects of Buttermilk on Serum LDL Cholesterol ConcentrationsNo drug interventionspreventionNot Availablecompleted
NCT02221297
Lipid-lowering Effect of a Plant Stanol Ester Supplement ProductNo drug interventionstreatmentNot Availablecompleted
NCT00175097
Soybean Based Diets and CVD Risk FactorsNo drug interventionstreatmentNot Availablecompleted
NCT00837083
Evaluation of Crestor® (Rosuvastatin) in Daily PracticeNo drug interventionsNot AvailableNot Availablecompleted
NCT01611883
A Study of the Effect of Ezetimibe on Glucose Metabolism in Type 2 Diabetics With Hypercholesterolemia (P06541)treatment4completed
NCT01882283
Effects of Black Tea Intake on Serum LipidsNo drug interventionsbasic_scienceNot Availablecompleted
NCT02072161
Evaluation of ETC-1002 vs Placebo in Patients Receiving Ongoing Statin Therapytreatment2completed
NCT03428061
The ZWOlle Transmural Integrated Care for CArdiovaScular Risk Management StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT00861861
Comparison of Pitavastatin With Atorvastatin in Increasing High Density Lipoprotein - Cholesterol (HDL-C) and Adiponectin in Patients With Dyslipidemia and Coronary Artery Disease (CAD)treatment4completed
NCT06293261
Multicenter, Prospective, Non-interventional, Observational Study to Confirm the Long-term Efficacy and Safety of Rosuampin Tab. in Patients With Hypertension and HypercholesterolemiaNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00654628
Begin With The Right Patients With Dual-Inhibition Action Therapy Through Vytorin for Newly Diagnosed Dyslipidemia Patients (0653A-172)(COMPLETED)treatment4completed
NCT05430828
Evaluation of Adherence, Persistence and Efficacy of Treatment With PCSK9 Inhibitors in ItalyNot AvailableNot Availablerecruiting
NCT00451828
Cholesterol and Pharmacogenetic Studyprevention4completed
NCT01322711
Atorvastatin, Aspirin, Oxidative Stress, Coagulation and Platelet Activation Indexestreatment4unknown_status
NCT00056511
Comparing Effects of 3 Sources of Garlic on Cholesterol LevelsNo drug interventionstreatment2 / 3completed
NCT01286311
Tailored Communication to Reduce Cardiovascular RiskNo drug interventionspreventionNot Availablecompleted
NCT00908011
Addition of Ezetimibe (Ezetrol®) to Ongoing Therapy With Rosuvastatin (Crestor®) in HIV Positive Patients Not Reaching Cholesterol TargetstreatmentNot Availablecompleted
NCT00895193
Alternative Options to Minimize Niacin-Induced Flushingsupportive_careNot Availablecompleted
NCT04806893
Study of Long-Term Efficacy and Safety of LIB003 in CVD or High Risk for CVD Patients Needing Further LDL-C Reductiontreatment3active_not_recruiting
NCT03604471
Lipid-lowering Therapy Individualizationother4completed
NCT01575171
Using Nudges to Implement Comparative EffectivenessNo drug interventionsNot AvailableNot Availablecompleted
NCT00687271
A Study of MK-6213 Co-Administered With Atorvastatin in Participants With Hypercholesterolemia (MK-6213-006)treatment2completed
NCT01562171
Lentils as a Functional Food to Improve Glucose and Decrease Cardiovascular RiskNo drug interventionsNot AvailableNot Availablecompleted
NCT00405171
Efavirenz to Nevirapine Switch and Low-Density Lipoprotein (LDL)-Dyslipidemiaprevention4completed
NCT00006071
Effects of Rosiglitazone on Blood Vessels in Patients With High Blood Pressure and High CholesterolNo drug interventionsNot AvailableNot Availablecompleted
NCT00651378
Switching to Rosuvastatin Versus Adding Ezetimibe to Atorvastatin Versus Doubling the Dose of Atorvastatin in Patients With Hypercholesterolemia and Risk Factors (P03708)treatment4terminated
NCT00005178
Study of Children's Activity and Nutrition (SCAN)No drug interventionsNot AvailableNot Availablecompleted
NCT00005478
Precursors of CVD Risk Factors--Project HeartbeatNo drug interventionsNot AvailableNot Availablecompleted
NCT00529178
Pravastatin Efficacy and Safety Trial in Hypercholesterolemic Patients With Chronic Liver Diseasetreatment4completed
NCT00256178
Efficacy of Lapaquistat Acetate and Simvastatin in Subjects With Primary Dyslipidemia.treatment3completed
NCT00766688
Evaluation of Safety and Efficacy of AVE5530 as add-on to Ongoing High Doses of Statins in Patients With Primary Severe HypercholesterolemiaNo drug interventionstreatment3terminated
NCT00423488
Ezetimibe and Simvastatin in Primary Hypercholesterolemia, Diabetes Mellitus Type 2, and Coronary Heart Disease (COMPLETED)treatment3completed
NCT04164888
Phase 2a Study to Assess CIVI 007 in Patients on a Background of Statin TherapyNo drug interventionstreatment2completed
NCT00653588
Polaris - Crestor 40 mg vs Atorvastatin 80 mg for 26 Weekstreatment3completed
NCT03366688
Single Ascending Dose Study of PCSK-9 Inhibitor (IBI306) in Healthy Subjects.other1completed
NCT02550288
A Clinical Trial to Assess the Efficacy and Safety of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-383)treatment3completed
NCT01812707
Efficacy and Safety Evaluation of Alirocumab (SAR236553/REGN727) in Patients With Primary Hypercholesterolemia on Stable Atorvastatin Therapy in Japantreatment2completed
NCT01190007
Open Label Study To Evaluate The Long-Term Safety Profiles Of Caduet In Japanese Patientstreatment4completed
NCT00754507
A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Atorvastatin for at Least 4 Weeks.treatment4completed
NCT01710007
Efficacy and Safety Study of Pitavastatin for Hypercholesterolemiatreatment3completed
NCT00797407
Effectiveness of Creatine in Preventing Muscle Aching From Cholesterol-Lowering Statin DrugsNo drug interventionssupportive_careNot Availablecompleted
NCT02644109
Effect On Serum Cholesterol Of Dairy Products With Addition Of Esterified PhytosterolsNo drug interventionstreatment4completed
NCT03559309
Investigating the Effects of Lipid-therapy Intensification With Alirocumab on Endothelial Function, Carotid Arteries, Lipoprotein Particle Subfractions, Inflammation and Post-prandial LipemiaNo drug interventionsdiagnostic4terminated
NCT00694109
An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-Hypercholesterolemiatreatment3completed
NCT05836909
Regulation of Lipid Metabolism in Guangzhou Individuals With Dyslipidemia by Red Yeast Rice, Phytosterol Esters and LycopeneNo drug interventionspreventionNot Availableenrolling_by_invitation
NCT00860509
Comparison of Low and High Phytosterol Diets With Respect to Cholesterol MetabolismNo drug interventionsbasic_scienceNot Availablecompleted
NCT05126056
Lipid Lowering Effect of Plant Stanol Ester in a Drinkable Non-dairy ProductNo drug interventionstreatmentNot Availableunknown_status
NCT00457756
The Effect of BiosLife on Serum LipidsNo drug interventionstreatmentNot Availablecompleted
NCT01849185
Probiotic BIO-25 as a Supplement to Statins for the Treatment of HypercholesterolemiaNo drug interventionstreatment4unknown_status
NCT01547585
A Human Trial to Assess the Low Density Lipoprotein Cholesterol (LDL-C) Lowering Effect of SoyNo drug interventionsbasic_scienceNot Availablecompleted
NCT01671085
A Study of LY3015014 in Healthy Participants With High Cholesterolbasic_science1completed
NCT05333315
Clinical Trials of Five Different Food Supplements With Restriction Diet in AdultsNo drug interventionspreventionNot Availablecompleted
NCT03510715
An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemiatreatment3completed
NCT00741715
Evaluation of Efficacy and Safety of AVE5530 Co-administered With Atorvastatin in Primary Hypercholesterolemiatreatment3terminated
NCT02342015
Effect of Atorvastatin on Bone-vascular Axisbasic_science4completed
NCT00407537
Caduet vs Usual Care in Subjects With Hypertension and Additional Risk Factorstreatment4completed
NCT00493337
A Community Pharmacist-led Intervention to Improve Adherence to Lipid-lowering TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT00144937
Multifactorial Intervention on Cardiovascular Risk Factors in Subjects With Peripheral Arterial DiseaseNo drug interventionseducational_counseling_training4unknown_status
NCT02409537
Effects of Dietary Antioxidants to Prevent Cardiovascular DiseaseNo drug interventionsprevention2completed
NCT06247137
Effect of a Food Supplementation With a Combined Food Supplement on Lipid Pattern, Indexes of Non-alcoholic Fatty Liver Disease and Systemic InflammationNo drug interventionstreatmentNot Availablecompleted
NCT00000532
Women's Healthy Lifestyle Project: Cardiovascular Risk Factors and MenopauseNo drug interventionsprevention3completed
NCT04358432
A Study of PCSK9 Inhibitor AK102 in Patients With Hypercholesterolemiatreatment2completed
NCT00730132
Observational Study of Approaches to Lipid-Lowering Therapy in Russian Patients With Coronary Heart Disease <<Treat to Goal>> (Study P05464)Not AvailableNot Availablecompleted
NCT05619952
Postprandial Lipemia and Glycemia Following a High-Fat MealNo drug interventionstreatmentNot Availablecompleted
NCT00755352
A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Pravastatin for at Least 4 Weeks.treatment4completed
NCT06507852
A Real-world Study of Inclisiran Adherence, Treatment Patterns, Patient Characteristics, and Effectiveness in ASCVD Patients With Hypercholesterolemia, ASCVD-risk Equivalent Patients With Hypercholesterolemia and Familial HypercholesterolemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT01879800
One-Day Acceptance and Commitment Training Intervention in Primary Care PatientsNo drug interventionstreatmentNot Availablecompleted
NCT04638400
Anti-inflammatory Effects of Simvastatinbasic_science4terminated
NCT01717300
A Study of the Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy (MK-0859-021)treatment3completed
NCT02173600
Cardiovascular Risk Factors And Intensive Dietary CounsellingNo drug interventionspreventionNot Availableunknown_status
NCT01212900
Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque RegressionNo drug interventionstreatment4completed
NCT03051100
Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg, Ezetimibe 10mg, and Atorvastatin 20 mg Triplet Therapy in Patients With Elevated LDL-Ctreatment2completed
NCT00546559
Differential Metabolic Effects of StatinsNot AvailableNot Availablecompleted
NCT02657759
EFFECTS OF CARDICHOL, AN HERBAL DIETARY SUPPLEMENT, IN MODERATE HYPERCHOLESTEROLEMIANo drug interventionspreventionNot Availableunknown_status
NCT02460159
A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384)No drug interventionstreatment3completed
NCT00927459
Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Liposomal siRNA in Subjects With High CholesterolNo drug interventionstreatment1terminated
NCT00344175
Follow-on Protocol of Pitavastatin Versus Simvastatin in Patients With Hypercholesterolemia or Dyslipidemia and Coronary Heart Disease Risk Factorstreatment3completed
NCT00254475
A Study to Evaluate the Efficacy of Valsartan/Simvastatin Combinations in Patients With Both Essential Hypertension and Hypercholesterolemiatreatment3completed
NCT05763875
Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy.treatment3completed
NCT01644175
Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With High Cardiovascular Risk and Hypercholesterolemia (ODYSSEY COMBO I)treatment3completed
NCT00080275
Evaluation of the Safety & Efficacy of a Combination of Niacin ER & Simvastatin in Patients With Dyslipidemia (OCEANS)treatment3completed
NCT02390375
Phase 3 Study to Evaluate the Efficacy and Safety of the DW0929 in Patients With Primary Hypercholesterolemiatreatment3completed
NCT02913170
Nattokinase Supplementation and Hemostatic FactorsNo drug interventionssupportive_care4completed
NCT01570270
Cheese Intake and HypercholesterolemiaNo drug interventionstreatment1 / 2completed
NCT06451770
Phase 1b Study of VERVE-201 in Patients With Refractory HyperlipidemiaNo drug interventionstreatment1not_yet_recruiting
NCT04784442
A Dose-finding Trial of ETC-1002(Bempedoic Acid) in Patients With Hypercholesterolemiatreatment2completed
NCT03739242
Effect of a Treatment With a Nutraceutical Combination on Sub-optimal LDL Cholesterol LevelsNo drug interventionstreatmentNot Availablecompleted
NCT00000542
Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)prevention3completed
NCT01625442
Crocus Sativus (Saffron) and Berberis Vulgaris (Barberry Fruit) in Metabolic Syndrometreatment4completed
NCT02314442
A Phase 1 Study of an Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C)treatment1completed
NCT05798442
The Impact of Using a Smartphone Health Application in the Improvement of Cardiovascular Disease Risk FactorsNo drug interventionspreventionNot Availablenot_yet_recruiting
NCT00136799
Efficacy and Safety of Fluvastatin in Different Doses in Adults With Mixed Dyslipidemia or Primary Hypercholesterolemiatreatment3completed
NCT02024399
Cardiovascular Risk Factors, Body Composition, Fitness Levels And Quality Of Life In Overweight And Obese 8-17 Year OldsNo drug interventionstreatmentNot Availablecompleted
NCT02654899
Single Dose Study of PF-06815345 in Healthy Subjectsbasic_science1terminated
NCT00092599
Investigational Drug Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-801)treatment3completed
NCT00093899
A Study to Evaluate an Investigational Drug in Patients With Mixed Hyperlipidemia (0653A-071)(COMPLETED)treatment3completed
NCT02634606
Effects of a Supplement Derived From Palm Oil on Cholesterol Levels in the Bloodprevention3terminated
NCT02734706
Efficacy of a LRC™ (L. Reuteri NCIMB 30242) Capsule on Managing Cholesterol in AdultsNo drug interventionstreatmentNot Availablecompleted
NCT02476006
Safety, Tolerability, and Effect of Alirocumab in High Cardiovascular Risk Patients With Severe Hypercholesterolemia Not Adequately Controlled With Conventional Lipid-modifying Therapies (ODYSSEY APPRISE)treatment3completed
NCT00319449
Adding Ezetimibe Tablet to Ongoing Treatment With Atorvastatin in Subjects With High Cholesterol and Multiple Coronary Heart Disease Risk Factors (Study P04060)(COMPLETED)treatment4completed
NCT00379249
Rosuvastatin ORBITAL Germanytreatment3completed
NCT01598649
Intervention With Lupin Protein-enriched Foods in Hypercholesterolemic SubjectsNo drug interventionspreventionNot Availablecompleted
NCT04289649
K-924 Phase III Confirmatory Studytreatment3completed
NCT01333436
A Study to Evaluate Fasting/Postprandial Serum Apolipoprotein B-48 (ApoB-48) Levels in Diabetic Participants With Normal to Moderately High Low Density Lipoprotein-C (LDL-C) Levels (MK-0653A-259 AM1)No drug interventionsdiagnosticNot Availablecompleted
NCT01941836
Evaluation of ETC-1002, Ezetimibe, and the Combination in Hypercholesterolemic Patientstreatment2completed
NCT04709536
A Study of IBI306 in Participants With Hypercholesterolemiatreatment3unknown_status
NCT00166036
Effect of Statins on Oxidative Stress and Endothelial Progenitor Cellstreatment2completed
NCT04897113
Study of Efficacy and Safety of the Plasmapheresis Method With Albumin Compensation Compared With the Plasmapheresis Method Without Albumin Compensation for Aging Biomarkers Correction in Men and Women Aged 40 to 55 Years OldNo drug interventionstreatmentNot Availableunknown_status
NCT00479713
A Study to Assess the Cholesterol Lowering Effect of an Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Patients With High Cholesterol and With High Cardiovascular Risk (0653A-809)(COMPLETED)treatment3completed
NCT01743313
Glucose Metabolism Disorders and Metabolic Syndrome Before and After Primary Hip and Knee ReplacementNo drug interventionsNot AvailableNot Availableterminated
NCT00005313
Human Lipoprotein Pathophysiology - Subproject: Genetics of Familial Combined HyperlipidemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT04258813
Onco-primary Care Networking to Support TEAM-based CareNo drug interventionspreventionNot Availablerecruiting
NCT00653913
Evaluation of Potential for Drug Interaction Between SCH 58235 (Ezetimibe) and Pitavastatin (Study P03962)(COMPLETED)treatment1completed
NCT03284918
Lipid Lowering Effect of a Cereal Based Snack Bar With Added Plant Stanol EsterNo drug interventionstreatmentNot Availablecompleted
NCT03867318
Efficacy and Safety Study of Ezetimibe (SCH 58235, MK-0653) in Addition to Atorvastatin in Participants With Coronary Heart Disease or Multiple Cardiovascular Risk Factors (P00693/MK-0653-030)treatment3completed
NCT03469518
Effect of β-cryptoxanthin (β-Cx), Plant Sterols and Galactooligosaccharides on Systemic and Gastrointestinal MarkersNo drug interventionsbasic_scienceNot Availableunknown_status
NCT00252018
The Effect of Broccoli Sprouts as a Nutritional Supplement in the Prevention of Cardiovascular DiseaseNo drug interventionspreventionNot Availablecompleted
NCT01228019
Niacin (+) Laropiprant (TREDAPTIVE) Re-examination Study (MK-0524A-119)Not AvailableNot Availableterminated
NCT01564719
Study of a Holistic Health Program for United Methodist ClergyNo drug interventionstreatmentNot Availablecompleted
NCT05459519
Effects of Dengzhanxixin Capsule on Platelet Function in Individuals at High Risk for Cardiovascular DiseaseNo drug interventionspreventionNot Availablerecruiting
NCT01580319
Primary Prevention of Cardiovascular Diseases in Childhood and Adolescence: the Role of Physical ActivityNo drug interventionstreatmentNot Availableterminated
NCT01931241
Safety Study of Bile Acid to Treat Hypercholesteremiatreatment1unknown_status
NCT01010841
Trial of Two Dietary Programs on Cardiometabolic Risk Factors in Subjects With Metabolic SyndromeNo drug interventionstreatmentNot Availablecompleted
NCT03067441
Assessment of the Long-Term Safety and Efficacy of Bempedoic Acid (CLEAR Harmony OLE)treatment3completed
NCT05192941
Study of Efficacy, Safety, Tolerability and Quality of Life of Inclisiran (KJX839) vs Placebo, on Top of Ongoing Individually Optimized Lipid-lowering Therapy, in Participants With Hypercholesterolemiatreatment4active_not_recruiting
NCT05000541
Observation of the Effects of Guideline-driven Lifestyle Interventions, Including Use of a Red-yeast Based NutraceuticalNo drug interventionsNot AvailableNot Availablecompleted
NCT05795517
Study of HSK31679 in Subjects With Hypercholesterolemia With Nonalcoholic Fatty Liver Disease(NAFLD)treatment2completed
NCT00132717
A 12 Week Study of MK0653A in Patients Who Have Been Hospitalized for a Possible Heart Problem (0653A-808)treatment3completed
NCT01448317
Ascending Dose Study of the Safety and Tolerability of Alirocumab (SAR236553/REGN727) in Japanese Healthy Volunteerstreatment1completed
NCT01882517
Lipid-lowering Effect of Plant Stanol YogurtNo drug interventionstreatmentNot Availablecompleted
NCT01894217
Statin Therapy to Improve Medication AdherenceNo drug interventionsprevention1completed
NCT04197817
A Single Dose Escalation Study of PCSK9 Inhibitor (JS002) in Health Subjectsother1completed
NCT00145717
China Plant Sterol Trialprevention3completed
NCT00214617
Effect of Crestor on Lipoprotein Metabolism in Humanstreatment4completed
NCT01574417
Plant Stanols and Gene Expression ProfileNo drug interventionspreventionNot Availablecompleted
NCT01670734
Pharmacokinetic and Tolerability of Alirocumab SAR236553 (REGN727) in Patients With Hepatic Impairment and in Healthy Subjectsbasic_science1completed
NCT00418834
Ezetimibe and Atorvastatin vs. Atorvastatin in Patients Age 65 and Older at High Risk for Coronary Heart Disease (CHD)(0653-112)treatment3completed
NCT06448234
Evaluating the Efficacy of AI-Guided (GenAIS TM) vs. Standard Physician-Guided Dietary Supplement Prescriptions for Lowering LDL Cholesterol in Hypercholesterolemic PatientsNo drug interventionstreatmentNot Availablecompleted
NCT05325034
Guideline Oriented Approach To Lipid Lowering In Asia-PacificNo drug interventionstreatmentNot Availablerecruiting
NCT00065624
Antioxidant Functions of Lipoic Acidtreatment2completed
NCT00092716
Comparing an Investigational Medication Versus an Approved Medication in Reducing Cholesterol Levels (0653-025)treatment3completed
NCT01925716
Effects of The Effects of Dietary Oils on Fasting Lipoprotein LipidsNo drug interventionspreventionNot Availablecompleted
NCT02508896
Study Assessing Safety, Immunogenicity and LDLc -Lowering Activity of 2 PCSK9 Targeting AFFITOPE Vaccines in Healthy SubjectsNo drug interventionstreatment1completed
NCT00523796
InPractice Survey on the Treatment of HypercholesterolemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT03590496
Safety and Efficacy of Propionate for Reduction of LDL CholesterolNo drug interventionspreventionNot Availablecompleted
NCT03882996
A Long-term Safety and Tolerability Study of Ezetimibe Plus Atorvastatin in Participants With Coronary Heart Disease, Multiple Risk Factors, or Hypercholesterolemia Not Controlled by Atorvastatin (P01418/MK-0653-032)treatment3completed
NCT01384058
Effect of Ezetimibe or Simvastatin or Both on Low Densitiy Lipoprotein -Subfractions in Patients With Type 2 Diabetestreatment4completed
NCT00526058
(H.E.L.P.)Apheresis Therapy to Compare the Reduction of LDL (Low Density Lipoprotein) CholesterolNo drug interventionsotherNot Availablecompleted
NCT02148458
Short Term Intermittent Fasting and Mediterranean DietNo drug interventionstreatmentNot Availablecompleted
NCT02078635
Magnetic Resonance Imaging-Portfolio Diet Study #7No drug interventionstreatmentNot Availablewithdrawn
NCT02260635
A Study of Evacetrapib (LY2484595) in Japanese Participants With Primary Hypercholesterolemiatreatment3terminated
NCT02089035
Replacement of Saturated Fat in Dairy on Total CholesterolNo drug interventionspreventionNot Availablecompleted
NCT00110435
A Multicenter Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Products in Patients With Type 2 Diabetes Mellitus and Hypercholesterolemia (MK-0653A-077)treatment3completed
NCT02314663
Effectiveness of a Combined Strategy to Improve Therapeutic Compliance and Degree of Control Among Patients With HypercholesterolaemiaNo drug interventionstreatmentNot Availableunknown_status
NCT00216463
Safety and Tolerability of Varying Load and Dose of ISIS 301012 in People With Elevated LDL-cholesterol LevelsNo drug interventionstreatment2completed
NCT00001963
Vascular Effects of Endothelium-Derived Versus Hemoglobin-Transported Nitric Oxide in Healthy SubjectsNo drug interventionstreatment1completed
NCT05174663
Investigating the Dose Response of an Almond-enriched Diet on Optimizing HDL-C in a Population With HypercholesterolemiaNo drug interventionstreatmentNot Availablecompleted
NCT06431763
A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.treatment4recruiting
NCT03718286
Effects of Acute, Rapid Lowering of LDL Cholesterol With Alirocumab in Patients With STEMI Undergoing Primary PCIprevention2completed
NCT00092586
Study of an Approved Drug With a Statin (a Medication That Lowers Cholesterol Levels) as Compared to Statin Therapy Alone in Patients With High Cholesterol (0653-040)treatment3completed
NCT02100839
Safety Study of AEM-28 to Treat Refractory Hypercholesterolemiatreatment1 / 2completed
NCT00005439
Evaluation of Childhood Blood Pressure and Lipid ScreeningNo drug interventionsNot AvailableNot Availablecompleted
NCT00754039
Study to Compare Welchol and TriCor to TriCor Alone in Patients With High Cholesteroltreatment4completed
NCT04247139
Kefir Cholesterol Lowering Pilot StudyNo drug interventionstreatmentNot Availablecompleted
NCT00570739
Effects of Metformin Hydrochloride (HCl) in Combination With Colesevelam HCl, Compared to Metformin HCl Alone, in Patients With Type 2 Diabetes Mellitus and the Effects of Colesevelam HCl on Lipids and Glucose on Pre-diabetic Patients.treatment3completed
NCT01448239
Injection Site Tolerability, Safety, Pharmacokinetics and Pharmacodynamics Study After a Single Dose Subcutaneous Treatment of Alirocumab SAR236553 (REGN727)treatment1completed
NCT00101439
A Study to Evaluate the Effects of Ezetimibe (MK-0653) on the Postprandial (Following a Meal) Lipoprotein Response in Participants With Primary Hypercholesterolemia (High Cholesterol) (MK-0653-072)(COMPLETED)treatment3completed
NCT05267522
Independent Effects of High-cholesterol (High-egg) and High-saturated Fat Diets on LDL-cholesterolNo drug interventionsbasic_scienceNot Availablecompleted
NCT00345722
The Effect of Strawberries in a Cholesterol-Lowering Dietary PortfolioNo drug interventionstreatment2completed
NCT00001622
Study of the Response of Human Small Blood VesselsNo drug interventionstreatment1completed
NCT05142722
Randomized Study to Evaluate the Effect of Obicetrapib on Top of Maximum Tolerated Lipid-Modifying Therapiestreatment3active_not_recruiting
NCT00654225
Treatment of Hypercholesterolaemia in South Asian Subjects (IRIS)treatment3completed
NCT04659525
Evolocumab Plus Ezetimibe in Haemodialized Statin-intolerant Patients With Hypercholesterolemiatreatment4unknown_status
NCT01617525
A Comparison of the Effects on Cardiovascular Risk Factors of Korean and American Dietary ProfilesNo drug interventionspreventionNot Availablecompleted
NCT01894230
Genetically Guided Statin TherapyNo drug interventionspreventionNot Availablecompleted
NCT03425630
LDL-cholesterol Lowering Effect of a New Dietary SupplementNo drug interventionstreatmentNot Availablecompleted
NCT05188430
Metabolic Effect of an Innovative Chitosan FormulationNo drug interventionstreatmentNot Availableunknown_status
NCT06435130
The Impact of Chokeberry Bioproducts on Metabolic Parameters and Antioxidant PotentialNo drug interventionspreventionNot Availablecompleted
NCT00496730
A Multicenter, Randomized, Open Label Study to Evaluate the Lipid Lowering Efficacy and Safety of Vytorin® 10/20 vs. Atorvastatin 10mg in Hypercholesterolemia Patients With Metabolic Syndrome in Korea (0653A-129)(COMPLETED)treatment3completed
NCT02260648
A Study of Evacetrapib (LY2484595) in Combination With Atorvastatin in Japanese Participants With Primary Hypercholesterolemiatreatment3terminated
NCT01081548
A Clinical Trial Study to Evaluate Efficacy and Safety of Atorvastatin in Korean Patients With HypercholesterolemiaNot Available4completed
NCT00462748
A Study to Determine the Number of Patients Who Reach Optimal Cholesterol Levels on Each of Three Different Treatments (0653A-121)treatment3completed
NCT00677248
LDL-Cholesterol Lowering Effect of KB2115 as Add on to Ezetimibetreatment2completed
NCT00224848
Guideline Adherence for Heart HealthNo drug interventionsprevention2completed
NCT02571257
Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients on Stable Statin Therapytreatment2completed
NCT04929457
Evaluation of a Digiphysical Screening Method to Identify and Diagnose Familial HypercholesterolemiaNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT00441857
Effect of Plant Stanols on Cholesterol AbsorptionNo drug interventionstreatment4completed
NCT00240357
Effect of an Internet Based Compliance Enhancement Tool in Subjects With HypercholesterolemiaNo drug interventionstreatment4withdrawn
NCT01964326
Actual Use Trial of Atorvastatin Calcium 10 mgtreatment3completed
NCT00105066
The Effects of Metformin on Blood Vessel Structure and Functiontreatment2completed
NCT05988866
Effects of a Digital Health Application (Lipodia) on LDL-cholesterol LevelsNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06450366
A Study to Evaluate the Efficacy and Safety of Enlicitide Decanoate (MK-0616, Oral PCSK9 Inhibitor) Compared With Ezetimibe or Bempedoic Acid or Ezetimibe and Bempedoic Acid in Adults With Hypercholesterolemia (MK-0616-018) CORALreef AddOntreatment3recruiting
NCT01566266
Gut Flora and Lipid Metabolismbasic_scienceNot Availablecompleted
NCT06220266
Effects of Phytoestrogen From Pueraria Mirifica in Improvement of Serum Lipid Parameters in Postmenopausal WomenNo drug interventionstreatment2 / 3recruiting
NCT03947866
Ezetimibe-Rosuvastatin Evaluation StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT01308866
Effectiveness of a Shared Decision Aid Tool for Cardiovascular Risk Prevention in Hypercholesterolemic PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT00000466
Postmenopausal Estrogen/Progestin Interventions (PEPI)prevention3completed
NCT01925365
Health Benefits of Whole Grain Oats in Population at Risk of Cardio-metabolic DiseaseNo drug interventionspreventionNot Availablecompleted
NCT01236365
Statins in Children With Type 1 Diabetes and Hypercholesterolemiatreatment3completed
NCT00349765
Effects of Various Higher Fat and Lower Fat Snacks on Cardiovascular Risk Factors in Men and Women.No drug interventionsprevention2completed
NCT06423365
A Tool to Help Patients With Muscle Symptoms After Taking a Statin Medication.No drug interventionshealth_services_researchNot Availablenot_yet_recruiting
NCT00863265
Phytosterols, Ezetimibe, and Cholesterol Metabolismbasic_science0completed
NCT01644474
Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Ezetimibe in Patients With Hypercholesterolemiatreatment3completed
NCT00145574
Efficacy and Safety of Colesevelam in Pediatric Patients With Genetic High Cholesteroltreatment4completed
NCT06481020
Plant Sterols on Cardiovascular Markers, Microbiota and Sterol Metabolism (Cardiofoodsterol)No drug interventionsbasic_scienceNot Availablerecruiting
NCT00000620
Action to Control Cardiovascular Risk in Diabetes (ACCORD)prevention3completed
NCT00720720
Effect of Phytosterols Enriched Products Consumption on Carotid Artery Artherosclerotic PlaqueNo drug interventionsotherNot Availablewithdrawn
NCT00932620
Comparison of Simvastatin Versus Simvastatin/Ezetimibe on Small Dense Low -Density Lipoprotein (LDL)treatment4completed
NCT02957682
Evaluating Effect of the Study Drug Praluent (Alirocumab) on Neurocognitive Function When Compared to Placebotreatment4completed
NCT02693782
Fabulous Fibre Study - Effect of Wheat Bran Extract on Gut and General Health in Healthy Aging Subjects (FFS)No drug interventionsbasic_scienceNot Availablecompleted
NCT02984982
Evaluation of Effect of Alirocumab on Coronary Atheroma Volume in Japanese Patients Hospitalized for Acute Coronary Syndrome With Hypercholesterolemiatreatment4completed
NCT00353782
Causes and Natural History of DyslipidemiasNo drug interventionsNot AvailableNot Availablerecruiting
NCT01435382
A Pharmacokinetic and Pharmacodynamic Study of PF-04950615 (RN316) in Subjects With Hypercholesterolemiabasic_science1completed
NCT01926782
Study to Evaluate the Efficacy and Safety of an Every Four Weeks Treatment Regimen of Alirocumab (REGN727/ SAR236553) in Patients With Primary Hypercholesterolemia (ODYSSEY CHOICE 1)treatment3completed
NCT01507831
Long-term Safety and Tolerability of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in High Cardiovascular Risk Patients With Hypercholesterolemia (ODYSSEY Long Term)treatment3completed
NCT00385931
Efficacy and Safety of Valsartan and the Combination of Valsartan and Simvastatintreatment3completed
NCT01206231
An Epidemiological Study Aimed to Record Standard Daily Practice in Managing Patients With HypercholesterolemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT01117831
An Analysis of Diabetes Control in Puerto RicoNo drug interventionsNot AvailableNot Availablecompleted
NCT00861731
Ezetimibe/Simvastatin Combination in Proteinuric Nephropathytreatment4unknown_status
NCT00652431
Assessment of Interaction Between Vytorin and Niaspan in Healthy Subjects (P04955AM2)treatment1completed
NCT04846231
Supplements, Placebo, or Rosuvastatin Studytreatment2completed
NCT00607373
Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial Hypercholesterolemiatreatment3completed
NCT00092573
Study of Ezetimibe and Fenofibrate in Patients With Mixed Hyperlipidemia (0653-036)(COMPLETED)treatment3completed
NCT01651273
A Safety Study of BMS-852927 in Subjects With HypercholesterolemiaNo drug interventionstreatment1terminated
NCT06112327
Long-term Follow-up of Participants Dosed With an Investigational Gene Editing Therapy for Cardiovascular DiseaseNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT00758927
The Effects of Omega-3 Fatty Acid (OMACOR) on the Low-density Lipoprotein (LDL) Sub-fraction in Type 2 Diabetic Patientstreatment4unknown_status
NCT01011127
Different Metabolic Effects of StatinsNot AvailableNot Availablecompleted
NCT02422927
Nutraceutical Combination in Patients With Low-grade Systemic InflammationNo drug interventionstreatment4completed
NCT04306627
Effect of Atorvastatin on Carotid Intima Media Thicknesstreatment4unknown_status
NCT00868127
Safety of Lapaquistat Acetate in Subjects With Hypercholesterolemiatreatment3completed
NCT00652327
Comparison of Ezetimibe Added to Ongoing Statin Therapy Versus Doubling the Dose of Statin in the Treatment of Hypercholesterolemia (P04355)treatment4completed
NCT00330876
Study of Pitavastatin in Elderly Patients With Primary Hypercholesterolemia or Combined Dyslipidemiatreatment3completed
NCT03001076
Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C (CLEAR Tranquility)treatment3completed
NCT00844376
Bioavailability Study for New Atorvastatin Formulationother4completed
NCT04148976
Effect of Dietary Intervention on LDL-C and Lipoprotein Subclasses Distribution in Patients With HypercholesterolemiaNo drug interventionstreatmentNot Availablecompleted
NCT02055976
Dose Ranging Study Of Bococizumab (PF-04950615; RN316) In Hypercholesterolemic Japanese Subjectstreatment2completed
NCT00848276
Sex Hormones and Blood PCSK9 LevelsNo drug interventionsNot AvailableNot Availablecompleted
NCT01266876
Study of the Safety and Efficacy of REGN727/SAR236553 in Patients With HeFH Hypercholesterolemiatreatment2completed
NCT00143676
Efficacy of Lapaquistat Acetate and Atorvastatin on Blood Cholesterol Levels in Subjects With Primary Hypercholesterolemiatreatment3completed
NCT00640276
Safety and Efficacy Study of Pitavastatin in Patient With a Metabolic Syndrometreatment4completed
NCT04158076
Evaluating the Efficacy and Safety of Co-administrated Rosuvastatin/Ezetimibe and Telmisartan/Amlodipinetreatment3completed
NCT05694260
A Phase 2 Clinical Study in Children With HeFH Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosingtreatment2recruiting
NCT01350960
Multiple Ascending Dose Study of SPC5001 in Treatment of Healthy Subjects and Subjects With FHNo drug interventionstreatment1terminated
NCT00133094
Systematic Management of High Cholesterol Utilizing Computer MonitoringtreatmentNot Availablecompleted
NCT00005694
Worksites, Occupational Nurses and Cholesterol ChangeNo drug interventionsNot AvailableNot Availablecompleted
NCT00477594
Open Label Extension of ISIS 301012 (Mipomersen) to Treat Familial Hypercholesterolemiatreatment2completed
NCT00654394
Progression of Carotid Artery Atheroma in Moderately Hypercholesterolemic Subjectstreatment3completed
NCT01817491
Low Fat Vegan or American Heart Association Diets & Cardiovascular Risk in Obese 9-18 y.o. With Elevated CholesterolNo drug interventionspreventionNot Availablecompleted
NCT01660191
A Study Comparing CoQ10 Levels While Taking 3 Different Statinstreatment4completed
NCT03065491
Effect of Red Yeast Rice, Phytosterols and L-tyrosol on Lipid Profile and Endothelial FunctionNo drug interventionstreatmentNot Availablecompleted
NCT00651391
Effect of Ezetimibe Plus Simvastatin on Flow-Mediated Brachial Artery Vasoactivity in Subjects With Primary Hypercholesterolemia (Study P03336)basic_science3terminated
NCT01251991
Cholesterol Lowering Treatment With Psyllium Husks and Isolated Soy Protein in Hypercholesterolemiatreatment4completed
NCT04289662
K-924 Phase III Long Term StudyNo drug interventionstreatment3completed
NCT01082562
Safety Study of BMS-844421 for Treatment of Hypercholesterolemiatreatment1terminated
NCT00329862
Laparoscopic Adjustable Gastric Banding With Truncal VagotomyNo drug interventionstreatmentNot Availableterminated
NCT01439880
Open Label Study of Long Term Evaluation Against LDL-C Trialtreatment2completed
NCT02634580
Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-4treatment3completed
NCT04433429
Nutraceuticals and Vascular RemodellingNo drug interventionsNot AvailableNot Availablecompleted
NCT00432029
Correlation of Flicker Induced and Flow Mediated Vasodilatation in Patients With Endothelial Dysfunction and Healthy Volunteers.No drug interventionsdiagnosticNot Availablecompleted
NCT00909389
Post-marketing Surveillance of the Safety, Tolerability and Efficacy of Vytorin (Ezetimibe + Simvastatin) Tablet Among Filipino Patients (Study P05647)Not AvailableNot Availablecompleted
NCT00650689
Ezetimibe Plus Atorvastatin Versus Atorvastatin in Untreated Subjects With Primary Hypercholesterolemia and Coronary Heart Disease (P03396)treatment3completed
NCT00321789
A Patient-Spouse Intervention for Self-Managing High CholesterolNo drug interventionsNot AvailableNot Availablecompleted
NCT00437892
Statins to Reduce D-dimer Levels in Patients With Venous Thrombosistreatment2terminated
NCT02721992
Graves' Orbitopathy and HypercholesterolemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT00687492
Centralized Pan-Asian Survey on the Under Treatment of HypercholesterolemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT01744392
Medication Adherence With Polyglot MeducationNo drug interventionshealth_services_researchNot Availablecompleted
NCT01285544
The Efficacy and Tolerability of Two Formulations of Atorvastatin In Korean Adult With Hypercholesterolemiatreatment4completed
NCT00240344
Study in High Risk Patients Switched From Higher Doses of Other Statins to Crestor on the Percentage of Patients Reaching the New LDL-C Target GoalNo drug interventionsNot AvailableNot Availablecompleted
NCT01960244
Study of Awareness and Detection of Familial HypercholesterolemiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT04270344
The Occurrence of MACE in Patients With AMI Receiving Pitavastatin/Valsartan TreatmentNot AvailableNot Availableunknown_status
NCT05680844
Peripheral Treg Cell Senescence & Serum Total Cholesterol LevelNo drug interventionsNot AvailableNot Availablerecruiting
NCT00704444
A 12-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05244)Not AvailableNot Availablecompleted
NCT00653744
Rosuvastatin Versus Atorvastatin in the Treatment of Hypercholesterolaemia in African American Subjects(ARIES)treatment3completed
NCT00917644
Bioequivalence Study Comparing A New 80 Mg Atorvastatin Tablet To A 80 Mg Atorvastatin Commercial Tabletother4completed
NCT00107744
Clinical Trial of Protein and Blood PressureNo drug interventionspreventionNot Availablecompleted
NCT01592240
Monthly And Twice Monthly Subcutaneous Dosing Of PF-04950615 (RN316) In Hypercholesterolemic Subjects On A Statintreatment2completed
NCT00542867
Pan-European Survey on the Under Treatment of HypercholesterolemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT00678067
Effects of Docosahexaenoic and Eicosapentaenoic Acids in Hypercholesterolemic Children Plus Diet on Docosahexaenoic Acid (DHA) StatusNo drug interventionstreatmentNot Availablecompleted
NCT04314167
Effect of Serum LDL Cholesterol Concentration on Pancreatic Insulin Secretionbasic_scienceNot Availableterminated
NCT02078167
Long Term Efficacy and Tolerability of a Nutraceutical Combination (Red Yeast Rice, Policosanols and Berberine) in Low-moderate Risk Hypercholesterolemic Patients: a Double-blind, Placebo Controlled StudyNo drug interventionstreatment4completed
NCT01666067
Vascular and Metabolic Effects of Vytorin vs Simvastatintreatment4completed
NCT02523001
Effect of Statin Treatment on Urinary AQP2 (uAQP2/01)No drug interventionsNot AvailableNot Availablecompleted
NCT00037401
Postprandial Lipemia and Endothelial Function in ACCORD- Ancillary to ACCORDNo drug interventionsNot AvailableNot Availablecompleted
NCT01979601
Safety, Tolerability, PK and PD of LGT209 in Healthy Volunteers and Patients With HypercholesterolemiaNo drug interventionstreatment1completed
NCT02043301
Pharmacokinetics And Relative Bioavailability Of Bococizumab (PF-04950615; RN316) When Administered To The Abdomen, Thigh Or Upper Armbasic_science1completed
NCT01606904
The Effect of CBT- Based Weight Loss Program on ObesityNo drug interventionstreatmentNot Availablecompleted
NCT00482404
Effects of Romantic Affection on Blood Chemistry and Immune ParametersNo drug interventionstreatment0completed
NCT01954472
Enhanced Multicenter Dietary Portfolio StudyNo drug interventionstreatmentNot Availablewithdrawn
NCT00413972
Effects of Vytorin Versus Placebo in Subjects With Primary Hypercholesterolemia (Study P04420)treatment3completed
NCT00090168
Cholesterol Lowering Level of MK0653A+Simvastatin in Patients With Hypercholesterolemia and Atherosclerotic or Coronary Vascular Disease (0653A-806)(COMPLETED)treatment3completed
NCT01630668
Efficacy of a One-a-Day L. Reuteri NCIMB 30242 Probiotic Supplement CapsuleNo drug interventionstreatment2completed
NCT00005468
Lipid Variability--Influence of StressNo drug interventionsNot AvailableNot Availablecompleted
NCT01825668
Effect of Plant Sterol Enriched Milk on Plasma Lipid Levels of Humans Breast-fed During InfancyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02585869
Efficacy and Safety of Gemcabene in Patients With Low HDL-C and Either Normal or Elevated Triglyceridestreatment2completed
NCT01288469
Efficacy and Safety Evaluation of Alirocumab (SAR236553/REGN727) When Co-administered With High Dose of Atorvastatin in Patients With Primary Hypercholesterolemiatreatment2completed
NCT01531569
Single Oral Dose of BeneFlax to Healthy Young and Older AdultsNo drug interventionsNot Available2completed
NCT00231569
Dose-escalating Safety Study in Subjects on Stable Statin TherapyNo drug interventionstreatment2completed
NCT00770146
Safety and Efficacy of Mipomersen (ISIS 301012) As Add-on Therapy in High Risk Hypercholesterolemic Patientstreatment3completed
NCT00707746
Safety and Efficacy Study of ISIS 301012 (Mipomersen) Administration in High Risk Statin Intolerant Subjectstreatment2completed
NCT00879112
Study of MB07811 in Subjects With Hypercholesterolemiatreatment2withdrawn
NCT00092612
Co-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-802)(COMPLETED)treatment3completed
NCT00533312
MK0524A Clinical Efficacy Study (0524A-026)(COMPLETED)treatment2completed
NCT03867110
An Efficacy and Safety Study of Ezetimibe (MK-0653, SCH 58235) in Addition to Atorvastatin Compared to Placebo in Participants With Primary Hypercholesterolemia (MK-0653-013)treatment3completed
NCT00879710
Effect of Diabetes Mellitus on Cholesterol MetabolismtreatmentNot Availablecompleted
NCT00396110
Evaluation of the Efficacy of Rosuvastatin in Daily Practice (TARGET)No drug interventionsNot AvailableNot Availablecompleted
NCT03611010
Dose-ranging Efficacy and Pharmacokinetics Study of Intravenous Atorvastatin in Hypercholesterolemic Patientstreatment2completed
NCT00536510
Effect of MK0524A on Cholesterol Levels (0524A-048)treatment3completed
NCT00286481
Efficacy of Lapaquistat Acetate Alone or Combined With Simvastatin in Subjects With Hypercholesterolemiatreatment3completed
NCT00981981
Effect of the Molecular Weight of Oat β-glucan on Its Ability to Lower Serum CholesterolNo drug interventionstreatment2completed
NCT00263081
Efficacy of Lapaquistat Acetate Co-Administered With Current Lipid-Lowering Treatment on Blood Cholesterol Levels in Subjects With Homozygous Familial Hypercholesterolemiatreatment3terminated
NCT00705081
Evaluation of the LDL-C Lowering Effects of Ezetimibe Achieved in Co-administration Therapy With Statins in an Indonesian Population (Study P04276)(COMPLETED)Not AvailableNot Availablecompleted
NCT04319081
Study to Evaluate Changes in Cognitive Function in Patients Treated With PCSK9 InhibitorsNo drug interventionsNot AvailableNot Availablecompleted
NCT00654095
Coadministration of Ezetimibe and Atorvastatin in Patients With Primary Hypercholesterolemia (P05456)treatment3completed
NCT04783714
Investigating Effects of a Novel Nutraceutical on Hypercholesterolaemia in Australian AdultsNo drug interventionstreatmentNot Availablecompleted
NCT02459314
Comparison of the Efficacy of Plant Sterol-Enriched Soymilk Versus Plain Soymilk in Volunteers With High LDL-CholesterolNo drug interventionstreatmentNot Availablecompleted
NCT00704314
Does Simvastatin Affect Insulin Sensitivity in Dyslipidemic Type 2 Diabetic Patients?basic_scienceNot Availablecompleted
NCT04397055
Oil Consumption and CholesterolNo drug interventionspreventionNot Availablecompleted
NCT05191355
Screening for Hypercholesterolemia in Children Using Dried Blood SpotNo drug interventionsNot AvailableNot Availablecompleted
NCT00430755
Improving the Quality of Patient Care by Using a Clinical Expert System.No drug interventionshealth_services_researchNot Availablecompleted
NCT00325455
MK0859 Dose-Ranging Study (0859-003)treatment2terminated
NCT01859455
Safety, Pharmacokinetics and Pharmacodynamics of LGT209 in Healthy Volunteers With Elevated Cholesterol and in Hypercholesterolemic Patients Treated With Statinstreatment1completed
NCT00005350
Evaluating Strategies to Control HypercholesterolemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT00324350
Intensive Glycemic Control and Skeletal Health StudyNo drug interventionsprevention3completed
NCT00163150
Vasomotor Reactivity In Cerebral Small Vessel Disease And New Approach To Treat Lacunar Stroketreatment4completed
NCT00029250
Garlic in Hyperlipidemia Caused by HAARTtreatment2withdrawn
NCT01443650
Injection Site Tolerability, Safety, Pharmacokinetics, Pharmacodynamics in Different Single-Dose Treatments of Alirocumab SAR236553 (REGN727) in Healthy Subjectstreatment1completed
NCT00639223
Safety of Red Yeast Rice for High Cholesterol in Individuals With Statin Intolerancetreatment2completed
NCT00814723
Fluvastatin 80 mg Ret. vs Combination With Ezetimibe 10 mg in Patients With High Cardiovascular Risktreatment4completed
NCT00433823
A Study Evaluating the Effects of Lipid Lowering Treatment on Steroid SynthesisNot Available4unknown_status
NCT00723723
Compliance With LDL-Lowering Therapy (Study P05467)(COMPLETED)No drug interventionsNot AvailableNot Availablecompleted
NCT03540108
The Efficacy of Cholesterol-lowering Probiotic Lactobacillus Plantarum LPLDL® in Hypercholesterolemic Adults.No drug interventionstreatmentNot Availablecompleted
NCT02316808
Cholesterol-lowering Effects of Plant Stanol EsterNo drug interventionstreatmentNot Availablecompleted
NCT01934608
The Effect of Synching Prescription Refills on AdherenceNo drug interventionspreventionNot Availablecompleted
NCT01054508
Effect of Tredaptive on Serum Lipoproteins and Inflammatory Markerstreatment4completed
NCT00092638
An Investigational Drug Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-804)(COMPLETED)treatment3completed
NCT03545438
Study to Evaluate the Safety, PK, and Pharmacodynamics of LIB003No drug interventionstreatment1completed
NCT03288038
The Efficacy and Safety of Combination Therapy of Rosuvastatin and Ezetimibe and Rosuvastatin Monotherapy in Patients With Primary Hypercholesterolemiatreatment3completed
NCT02331043
Serum Cholesterol Reduction Efficacy of Biscuit With Plant Stanol EsterNo drug interventionstreatmentNot Availablecompleted
NCT01661543
U of A/ U of M Beans and Peas Health Claim ProjectNo drug interventionstreatmentNot Availablecompleted
NCT00690443
Evaluate Safety and Efficacy of AEGR-733 and Atorvastatin vs Atorvastatin Monotherapy in Hypercholesterolemiatreatment2completed
NCT01107743
Amlodipine/Atorvastatin (Caduet®) Drug Use Investigation (Regulatory Post Marketing Commitment Plan)Not AvailableNot Availablecompleted
NCT04173403
A Long-term Study of AK102 in Patients With Hypercholesterolemiatreatment2completed
NCT02317003
Physical Exercise Prescription With PEdometeR in General Practice for Patients With Cardiovascular Risk Factors - PEPPERNo drug interventionspreventionNot Availablecompleted
NCT02808403
Long Term Post Marketing Specified Drug Use Result Survey for Evolocumab in JapanNo drug interventionsNot AvailableNot Availablecompleted
NCT01768403
Centralised Pan-Algerian Survey on the Undertreatment of HypercholesterolemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT01370603
A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/40 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 40 mg Tablets in Participants With High Cholesterol (MK-0653C-190 AM1)treatment3completed
NCT00923403
Efficacy of Sterol-Fortified Low Fat Soy Beverage on Cholesterol Metabolism, Inflammation and Oxidative Status in Humans - Study IINo drug interventionstreatment1 / 2completed
NCT02628990
Lipid-lowering Effect of Plant Stanol Ester Yoghurt DrinksNo drug interventionstreatmentNot Availablecompleted
NCT01716390
Lipid-lowering Effect of Plant Stanol DrinkNo drug interventionstreatmentNot Availablecompleted
NCT00092664
An Extension Study of An Investigational Drug in Patients With Hypercholesterolemia (0653A-038)(COMPLETED)treatment3completed
NCT02587364
Pharmacokinetics and Pharmacodynamics Study of Gemcabene in Healthy Volunteersbasic_science1completed
NCT02341664
Patient and Provider Assessment of Lipid Management RegistryNo drug interventionsNot AvailableNot Availablecompleted
NCT00318864
Biological CVD Risk Factors in Older Depressed PatientsNo drug interventionstreatmentNot Availablecompleted
NCT00660764
Assessment of the Efficacy of Rosuvastatin in Patient Groups With a Dissimilar Risk Profile in an Observational Study (HEROS)Not AvailableNot Availablecompleted
NCT04927221
Multiple Ascending Dose Study to Evaluate the Safety, Tolerability of DC371739 Treatment in HypercholesterolemicNo drug interventionstreatment1completed
NCT01678521
Effect of LDL-apheresis on PTX3 Plasma Levels in Hypercholesterolemic PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT05750602
Combined Effect of LIMICOL and Physical Activity on LDL Cholesterol and Muscle Function.No drug interventionssupportive_careNot Availablecompleted
NCT05467384
Effect of Amlodipine on the Lipid Profile of Newly Diagnosed Hypertensive Patientstreatment4completed
NCT01126684
Effects of Atorvastatin on Blood Pressure and Urinary Albumin ExcretiontreatmentNot Availablecompleted
NCT00782184
Ezetimibe/Simvastatin (10 mg/40 mg) vs. the Doubling of Atorvastatin in High Risk Participants (MK-0653A-134 AM1)(COMPLETED)treatment3completed
NCT06243484
Effect of the Food Supplement TOTUM-070 on Lipid MetabolismNo drug interventionspreventionNot Availableactive_not_recruiting
NCT01751984
A Study of the Efficacy and Safety of ETC-1002 in Participants With Statin Intolerancetreatment2completed
NCT02739984
Evaluation of Evolocumab (AMG 145) Efficacy in Diabetic Adults With Hypercholesterolemia/Mixed Dyslipidemiatreatment3completed
NCT00753779
A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Simvastatin for at Least 4 Weeks.treatment4completed
NCT01077479
Metformin in Preventing Androgen Deprivation Therapy Induced Insulin Resistance and Metabolic Syndromeprevention2completed
NCT00240279
The Effect of Rosuvastatin on Aortic Stiffness in Hemodialysis Patients in the AURORA Studytreatment3completed
NCT01446679
Special Drug Use-Results Survey of Lipitor TabletsNot AvailableNot Availablecompleted
NCT00423579
The Effects of Ezetimibe/Simvastatin 10/20 mg Versus Simvastatin 40 mg in High Cholesterol and Coronary Heart Disease Study (P04039AM2)(COMPLETED)treatment4completed
NCT02023879
Phase III Study To Evaluate Alirocumab in Patients With Hypercholesterolemia Not Treated With a Statin (ODYSSEY CHOICE II)treatment3completed
NCT00917579
Bioequivalence Study Comparing A New 10 Mg Atorvastatin Tablet To A 10 Mg Atorvastatin Commercial Tabletother4completed
NCT00311987
Study of 3,5-Diiodothyropropionic Acid (DITPA) in Hypercholesterolemic Patientstreatment1 / 2terminated
NCT01702987
Evaluation of Ubiquinol on Mitochondrial Oxidative Capacity in Statin Patients Using 31PMRSdiagnosticNot Availablecompleted
NCT03381287
A Multiple Ascending Dose Study of HTD1801 in Adults With HypercholesterolemiaNo drug interventionstreatment1 / 2completed
NCT01340287
Effect of the Consumption of a Fermented Milk Enriched With Plant SterolsNo drug interventionsbasic_scienceNot Availablecompleted
NCT01604733
Centralized Pan-Middle East Survey on the Undertreatment of HypercholesterolemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT03346733
The Effect of Psyllium Fibre on LDL-C, Non-HDL-C, and Apolioprotein-B: A Systematic Review and Meta-analysisNo drug interventionsNot AvailableNot Availableunknown_status
NCT00327054
Effectiveness of Nigella Sativa (Kalonji) Seed in DyslipidemiaNo drug interventionstreatment1 / 2completed
NCT00860054
Addition of Phytosterols to a Low Phytosterol DietNo drug interventionsbasic_scienceNot Availablecompleted
NCT06567951
Extra Virgin Olive Oil Supplementation in Pregnancies With Increased Cholesterol LevelsNo drug interventionsbasic_scienceNot Availablenot_yet_recruiting
NCT00005151
Pawtucket Heart Health ProgramNo drug interventionsNot AvailableNot Availablecompleted
NCT03587051
Low Versus High-glycemic Index Post-exercise Diets for Improving Metabolism and Body CompositionNo drug interventionspreventionNot Availablecompleted
NCT00999453
The Effects of Lowering Low-density Lipoprotein Cholesterol Levels to New Targets on Cardiovascular Complications in Peritoneal Dialysis PatientsNo drug interventionstreatmentNot Availablecompleted
NCT02911753
Feasibility and Acceptability of a Beverage Intervention for Hispanic AdultsNo drug interventionstreatmentNot Availablecompleted
NCT04397653
Evolocumab Plus Ezetimibe in High Risk Haemodialized Statin Intolerant Patientstreatment4unknown_status
NCT02989753
Effects of Two Herbal Dietary Supplements on Lipid Metabolism in Moderate Hypercholesterolemia and HypertriglyceridemiaNo drug interventionsprevention1 / 2completed
NCT01031277
Centralized Pan-Middle East Survey on the Under-treatment of Hypercholesterolemia, Sub-study for the Gulf StatesNo drug interventionsNot AvailableNot Availablecompleted
NCT01767077
Role of Milk Fat Globule Membranes in Dairy Foods: Health Effects in HumansNo drug interventionsbasic_scienceNot Availablecompleted
NCT00000477
Cholesterol Reduction in Seniors Program (CRISP)prevention2completed
NCT03193047
Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg When Added to PCSK9 Inhibitor Therapytreatment2completed
NCT02251847
The Efficacy and Safety of a Combination Therapy of Rosuvastatin and Ezetimibe Versus Monotherapy of Rosuvastatin in Hypercholesterolemia Patientstreatment3unknown_status
NCT01660945
Vascular and Metabolic Effects of Vytorintreatment4completed
NCT00160745
Rosuvastatin and Renal Endothelial Functionprevention2completed
NCT00548145
The Clinical Study of Pitavastatin Treatment for Group of Mild to Moderate Alzheimer's DiseasetreatmentNot Availableterminated
NCT00090298
Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Drugs in Patients With Elevated Cholesterol Levels (0653A-058)treatment3completed
NCT00937898
Beef in an Optimal Lean Diet (BOLD) Effects on Cardiovascular Disease (CVD) RiskNo drug interventionspreventionNot Availablecompleted
NCT05069298
Effect of Silibinin(A) as a Potential Anti-obesity AgentNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT02178098
Evaluation of ETC-1002 in Participants With Hypercholesterolemia and Hypertensiontreatment2completed
NCT03429998
Evolocumab Versus LDL Apheresis in Patients With Hypercholesterolemiatreatment3completed
NCT02107898
Efficacy and Safety Evaluation of Alirocumab in Patients With Heterozygous Familial Hypercholesterolemia or High Cardiovascular Risk Patients With Hypercholesterolemia on Lipid Modifying Therapy (ODYSSEY JAPAN)treatment3completed
NCT04666298
Study of Efficacy and Safety of Inclisiran in Japanese Participants With High Cardiovascular Risk and Elevated LDL-Ctreatment2completed
NCT05546398
SurveY Followed by a Retrospective Chart Review to Describe the Key Factors Leading to Physician's Decision to Treat Patients at High and Very High Cardiovascular Risk With hyperchOlesterolemia or Mixed Dyslipidemia With NUSTENDI®Not AvailableNot Availablecompleted
NCT06579898
The Effect of Progressive Resistance Exercise Training (PRET) on CVRF in Adults With ID.No drug interventionstreatmentNot Availablecompleted
NCT04133805
The Effect of Viscous Dietary Fibers on LDL-cholesterolNo drug interventionsNot AvailableNot Availableunknown_status
NCT06488105
Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trialprevention2recruiting
NCT04574505
Food Supplementation With Eufortyn Colesterolo Plus for LDL Modulation in Subjects With Polygenic HypercholesterolemiaNo drug interventionstreatmentNot Availablecompleted
NCT00535405
A Study to Assess the Cholesterol Lowering Effect of Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Elderly Patients With High Cholesterol at High or Moderately High Risk for Coronary Heart Disease (0653A-128)treatment3completed
NCT02608697
A Study to Assess the Safety and Efficacy of CAT-2054 in Combination With Atorvastatin in Patients With Hypercholesterolemiatreatment2completed
NCT06005597
Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapiestreatment3active_not_recruiting
NCT00442897
Vytorin (10/20 Or 10/40) Compared to Atorvastatin (10 mg or 20 mg) in Patients With Coronary Artery Disease (0653A-126)(COMPLETED)treatment4completed
NCT01581697
Impact of Consumption of Oats in Lipid Profile of Children and Adolescents With DyslipidemiaNo drug interventionsNot Available1 / 2unknown_status
NCT04073797
PET Imaging of Inflammation and Lipid Lowering StudydiagnosticNot Availablerecruiting
NCT00268697
Efficacy of Lapaquistat Acetate Alone and With Ezetimibe in Subjects With Primary Dyslipidemia.treatment3completed
NCT00552097
Effect of Ezetimibe Plus Simvastatin Versus Simvastatin Alone on Atherosclerosis in the Carotid Artery (ENHANCE)(P02578)prevention3completed
NCT02818283
Soy Modulation of Immune Activation, LDL- Levels, and Lowering Inflammation by Pretzel Isoflavone Dietary InterventionNo drug interventionspreventionNot Availableterminated
NCT02728583
The Effects of a Spread With Added Plant Sterols and Omega-3 Fatty Acids on Blood LipidsNo drug interventionsbasic_scienceNot Availablecompleted
NCT03479983
Effect of Indian Gooseberry Extract (AMX160) in HypercholesterolemiaNo drug interventionstreatmentNot Availableunknown_status
NCT00288483
Cholesterol-Lowering Effects of PolicosanolNo drug interventionstreatment3terminated
NCT03446261
Rosuvastatin/Ezetimibe vs Rosuvastatin in Korean Patients With Type 2 Diabetes Mellitus and HypercholesterolemiaNo drug interventionstreatment4completed
NCT00217061
Effect of a Decision Aid About Statin Use in Patients With Type 2 Diabetes MellitusNo drug interventionsNot Available3completed
NCT01982461
A Study to Evaluate the Efficacy and Safety of Rosuvastatin in Hypercholesterolemia.treatmentNot Availableunknown_status
NCT04866628
Clinical Trials of Two Helichrysum Infusions in AdultsNo drug interventionspreventionNot Availablecompleted
NCT00865228
Efficacy of Lapaquistat Acetate in Subjects With Hypercholesterolemiatreatment2terminated
NCT02664428
Measuring the Impact of Dietary Supplementation With a New Baking Product on Gut Microbiota and Cholesterol MetabolismNo drug interventionsbasic_scienceNot Availablecompleted
NCT00532311
Efficacy of Lapaquistat Acetate Co-Administered With Statins in Subjects With Hypercholesterolemiatreatment3terminated
NCT03216811
Nutraceutical in Cardiovascular Primary PreventionNo drug interventionstreatment2completed
NCT03172611
A Defined, Plant-based, 4-week Dietary Intervention Reduces Lp(a) and Other Atherogenic ParticlesNo drug interventionstreatmentNot Availablecompleted
NCT00705211
A 52-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05245)Not AvailableNot Availablecompleted
NCT01342211
A Multiple Dose Study of PF-04950615 (RN316) in Subjects on High Doses of Statinstreatment2completed
NCT00536211
Physical Inactivity and Insulin Resistance in Skeletal Muscle.treatmentNot Availablewithdrawn
NCT00171093
A 10-12 Week Study to Evaluate the Safety and Efficacy of 320 mg Valsartan and 80 mg Simvastatin in Combination and as Monotherapies in Treating Hypertension and Hypercholesterolemiatreatment3completed
NCT00438893
Effects of a Long Term Dietary Portfolio and of Sequential Removal of Food Components From the DietNo drug interventionstreatmentNot Availablecompleted
NCT04485793
Effect of a Dietary Supplement on Lipid Pattern and Liver Parameters in HypercholesterolemiaNo drug interventionstreatmentNot Availablecompleted
NCT02223793
Vascular Lifestyle-Intervention and Screening in PharmacyNo drug interventionsscreeningNot Availableunknown_status
NCT00000471
Lifestyle Heart TrialNo drug interventionsprevention2completed
NCT06568471
A Study on Efficacy and Safety of HST101 in Chinese Patients With Hypercholesterolemiatreatment3not_yet_recruiting
NCT00150371
Canadians Achieve Cholesterol Targets Fast With Atorvastatin Stratified Titrationtreatment3completed
NCT01959971
Effect of Alirocumab on Lipid Metabolism in Adults With Elevated LDL-Cholesterolbasic_science1completed
NCT00202878
IMPROVE-IT: Examining Outcomes in Subjects With Acute Coronary Syndrome: Vytorin (Ezetimibe/Simvastatin) vs Simvastatin (P04103)treatment3completed
NCT01108978
Evaluating the Efficacy and Safety of Dehypotin® in the Patients With Type 2 Diabetes Mellitus or Cardiovascular DiseaseNo drug interventionstreatment4terminated
NCT00293878
Study on the Safety and Effects on Lipids of FM-VP4 in Subjects With Primary Hypercholesterolemiatreatment2completed
NCT01803178
The Effect of Plant Sterols on Vascular FunctionNo drug interventionssupportive_careNot Availablecompleted
NCT00637078
STITCH2 (Simplified Therapeutic Intervention to Control Hypertension and Hypercholesterolemia)No drug interventionstreatment4completed
NCT00139178
Switching From Zidovudine to an NNRTI or Lopinavir/Ritonavir in Patients Treated With Zidovudine/ Lamivudine/Abacavir.No drug interventionstreatment4completed
NCT05421078
A Dose-Finding Study in Japanese Patients to Evaluate the Effect of Obicetrapib as an Adjunct to Stable Statin Therapy.treatment2completed
NCT01025388
Centralized Pan-Middle East Survey on the Undertreatment of HypercholesterolemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT01644188
Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Ezetimibe on Top of Statin in High Cardiovascular Risk Patients With Hypercholesterolemia (ODYSSEY COMBO II)treatment3completed
NCT00241488
DISCOVERY Asia - Crestor in Type IIa and IIb Hypercholesteremiatreatment3completed
NCT01624207
The Efficacy and Safety of Atorva® 20mg Versus Lipitor® 20mgtreatment4completed
NCT01723007
Weight Loss Associated With the Consumption of AppleNo drug interventionsNot AvailableNot Availablecompleted
NCT00185107
Effect of Combination Therapy With Two Drugs (Colesevelam and Ezetimibe) in Patients With High Cholesteroltreatment4completed
NCT00654407
Mercury II - Compare the Efficacy and Safety of Lipid Lowering Agents Atorvastatin and Simvastatin With Rosuvastatin in High Risk Subjects With Type IIa and IIb Hypercholesterolemiatreatment3completed
NCT00698256
Effect of High Stanol Ester Dose on Serum Lipids, Carotenoids and Fat-soluble VitaminsNo drug interventionssupportive_careNot Availablecompleted
NCT05952856
A Study of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef LipidsNo drug interventionstreatment3active_not_recruiting
NCT02288585
The Effect of Plant Sterols on the Blood Lipid Profile of Subjects With and at High Risk of Type 2 Diabetes MellitusNo drug interventionsbasic_scienceNot Availablecompleted
NCT02499185
Study Evaluating Novel Biomarkers of AKI (Acute Kidney Injury) in Post-operative PatientsNo drug interventionsdiagnostic4terminated
NCT00723385
Effects of Vitamin D on LipidsNo drug interventionsNot AvailableNot Availablecompleted
NCT04289285
Safety and Efficacy of IBI306 in Chinese Subjects With Non-familial Hypercholesterolemiatreatment3completed
NCT03593785
A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD8233 in Healthy Male Subjects With Increased Elevated LDL-C Levels.No drug interventionstreatment1completed
NCT06304415
Elevated Lipoprotein(a) in Hospital StaffNo drug interventionsNot AvailableNot Availablerecruiting
NCT02988115
Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia and Statin Intoleranttreatment3completed
NCT00051415
Safety and Effectiveness of Flaxseed for Reducing High CholesterolNo drug interventionstreatment2 / 3completed
NCT02979015
A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous (SC) Administered Alirocumab in Healthy Chinese Subjectstreatment1completed
NCT01623115
Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapytreatment3completed
NCT00654537
STELLAR-Rosuvastatin vs. Atorvastatin, Pravastatin, Simvastatin Across Dose Rangestreatment3completed
NCT00690937
A Multicenter, Active and Placebo-controlled Study of Enteric Coated Sevelamer in Patients With Mild to Moderate Hypercholesteremiatreatment2completed
NCT01720537
A Study To Assess The Safety Of PF-05335810 In Hypercholesterolemic Subjectsbasic_science1completed
NCT00945737
A Study on the Effects of Soy Protein on Blood Lipids in Men and Women With Mild to Moderate HypercholesterolemiaNo drug interventionsbasic_scienceNot Availablecompleted
NCT03872232
Evaluating the Efficacy and Safety of Co-administrated Rosuvastatin/Ezetimibe and Telmisartantreatment3completed
NCT04376632
Diets Enriched With PecansNo drug interventionsotherNot Availablecompleted
NCT00115232
Inflammatory Profiles of Children at High Risk for AtherosclerosisNo drug interventionsNot AvailableNot Availablecompleted
NCT00769132
A Study to Evaluate the Effects of Extended Release (ER) Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites in Subjects With High Cholesterol (0524A-075)(COMPLETED)treatment1completed
NCT06127732
Phytosterol Supplementation and Lipoprotein SubfractionsNo drug interventionstreatmentNot Availablecompleted
NCT01493752
Investigation of the Effect of Dietary Nitrate Treatment on Endothelial Function and Platelet Reactivity in Hypercholesterolemics.No drug interventionsNot Available1completed
NCT00001752
Vascular and Metabolic Effects of Hormone Therapy Combined With L-Arginine in Postmenopausal Womentreatment2completed
NCT04511000
Clinical Trial to to Compare of the Efficacy and Safety of Lipilou® 20 mg and Lipilou® 10 mgtreatment4completed
NCT03394859
Electronic Medical Records and Genomics (eMERGE) Phase IIINo drug interventionsNot AvailableNot Availablecompleted
NCT00000459
Dietary Intervention Study in Children (DISC)No drug interventionsprevention3completed
NCT05234775
Cross-Over Study to Compare the Pharmacokinetics and Pharmacodynamics of LIB003 Process 1 and Process 2 Drug Producttreatment3completed
NCT00457275
Observational Study to Evaluate LDL-C Lowering Effect of Ezetimibe (0653-070)treatment3completed
NCT05004675
Trial to Evaluate Efficacy and Safety of LIB003 and Inclisiran in High-risk CVD Patientstreatment3active_not_recruiting
NCT04536870
Statins in Reducing Events in the Elderly (STAREE) Heart Sub-studyNo drug interventionspreventionNot Availableactive_not_recruiting
NCT02969070
Effects of Nutraceutical Therapies on Endothelial Function, Platelet Aggregation, and Coronary Flow ReserveNo drug interventionstreatmentNot Availablecompleted
NCT03830970
Effect of Canned Beans of Multiple Varieties in Daily Amounts of 1 Cup and 1/2 Cup on Serum LDL Cholesterol and Other Cardiovascular Disease Risk Biomarkers in Adults With Elevated LDL CholesterolNo drug interventionspreventionNot Availablecompleted
NCT00001742
The Role of Cyclooxygenase Activity in the Endothelial Function of Hypertensive and Hypercholesterolemic PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT06334042
Examination of the Effects of Chromium Levels on Glucose Metabolism, Lipid Metabolism, Morbidity and Mortality Rates in Patients Followed in Intensive Care UnitNo drug interventionsNot AvailableNot Availablerecruiting
NCT00621699
Pharmacokinetic Drug Interaction Between Ezetimibe and Tacrolimus After Single Dose Administration in Healthy Subjectsbasic_science1completed
NCT00249899
Efficacy of Lapaquistat Acetate Alone or Combined With High-Dose Statin Therapy in Subjects With Hypercholesterolemiatreatment3terminated
NCT05988099
Comparison of the Effects of Standardized Chokeberry Extracts With Various Formulations on the Levels of Selected Markers Associated With Cardiovascular DiseaseNo drug interventionsotherNot Availablecompleted
NCT00335699
Korean Rosuvastatin Effectiveness Study in Nondiabetic Metabolic Syndrometreatment4completed
NCT06301906
Red Yeast Rice for Primary Prevention of HypercholesterolemiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT00463606
A Multicenter Study Comparing the Safety and Efficacy of ABT-335 and Rosuvastatin Calcium Combination Therapy to Monotherapy in Subjects With Dyslipidemiatreatment3completed
NCT06391606
CoQ10 in Statin-associated AstheniaNo drug interventionstreatmentNot Availablecompleted
NCT01406106
Effect of Plant Sterols on the Lipid Profile of Patients With HypercholesterolaemiaNo drug interventionstreatmentNot Availableunknown_status
NCT04753606
Randomized Study of Obicetrapib as an Adjunct to Statin Therapytreatment2completed
NCT02938949
Alirocumab in Patients With Acute Myocardial Infarctiontreatment4completed
NCT01085149
The Effect Of Simvastatin On Bone Remodeling In Socket Of Mandibular TeethNot AvailableNot Availableunknown_status
NCT05574049
Weight Loss, Blood Sugar and Blood Lipid Effects of Tetrahydrocannabivarin (THCV) Impregnated Mucoadhesive Stripstreatment0completed
NCT05017649
Role of A2A Receptor in Hypercholesterolemic PatientsNo drug interventionsdiagnosticNot Availablerecruiting
NCT01420549
Efficacy/Safety of Rosuvastatin+Ezetimibe in High Risk Patients With Primary Hypercholesterolemia/Mixed Dyslipidemiatreatment3completed
NCT02591836
Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients as Monotherapy or in Combination With Atorvastatintreatment2completed
NCT00005336
Dietary Treatment of Hyperlipidemia in Women vs. MenNo drug interventionsNot AvailableNot Availablecompleted
NCT00745836
Effects of Atorvastatin on Adiponectin Levels and Insulin Sensitivity In Hypercholesterolemic Patientstreatment4completed
NCT01154036
MK0653C in High Cardiovascular Risk Patients With High Cholesterol (Switch Study)(MK-0653C-162)treatment3completed
NCT02368613
A Clinical Trial for Evaluation of Adequate Dose and Safety of DW-3102 in Hypercholesterolemia PatientsNo drug interventionstreatment2unknown_status
NCT04790513
Trial to Evaluate Efficacy and Safety of LIB003, Evolocumab and Alirocumab in High-risk CVD Patientstreatment3completed
NCT01709513
Study of Alirocumab (REGN727/SAR236553) in Patients With Primary Hypercholesterolemia and Moderate, High, or Very High Cardiovascular (CV) Risk, Who Are Intolerant to Statins (ODYSSEY ALTERNATIVE)treatment3completed
NCT01341613
Efficacy of Cardioviva™ Probiotic Supplement Capsule FormulationNo drug interventionstreatment2completed
NCT00005718
Evaluation of Cholesterol Education for At-Risk ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT02475018
The Effect of Shuhua Milk Fortified With Plant Sterol Esters on Serum Cholesterol in HumanNo drug interventionspreventionNot Availablecompleted
NCT04573218
Supplementation of Oil Palm Phenolics to Improve Lipid Profile in Subjects With Minor HyperlipidaemiaNo drug interventionstreatment2completed
NCT00120718
The Effect of Fasudil on Vascular Function in Humanstreatment2completed
NCT02991118
Evaluation of Long-Term Efficacy of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia at High Cardiovascular Risktreatment3completed
NCT00683618
Compare the Efficacy of Rosuvastatin to Atorvastatin in High Risk Patients With Hypercholesterolemiatreatment3completed
NCT01325818
The Effects of Pravastatin and Rosuvastatin on Coronary Plaques in Patients With Stable Angina Pectoristreatment4unknown_status
NCT01408719
Effect of Beta-Glucan on Cholesterol LoweringNo drug interventionspreventionNot Availablecompleted
NCT00650819
Comparison of Ezetimibe Plus Simvastatin Versus Ezetimibe or Simvastatin Alone in Subjects With Primary Hypercholesterolemia (Study P03757)(COMPLETED)treatment3completed
NCT01660919
Vascular and Metabolic Effects of Rosuvastatintreatment4completed
NCT01242319
Translating ATP III Cholesterol Management Guidelines Into Primary Care PracticeNo drug interventionsNot AvailableNot Availablecompleted
NCT01350141
A Multiple Dose Study Of PF-04950615 (RN316) In Subjects On Maximum Doses Of Statinstreatment2completed
NCT00905541
Influence of Simvastatin on Apolipoprotein B-100 (apoB-100) Secretionbasic_scienceNot Availablecompleted
NCT00141141
Efficacy And Safety Study Of Atorvastatin Versus Simvastatin In Type 2 Diabetic Subjects With Hypercholesterolemiatreatment4completed
NCT04669041
A Study to Evaluate the Efficacy and the Safety of Single Pill Combination (SPC) Ezetimibe/Rosuvastatin in Chinese Adult Patients With Primary Hypercholesterolemia Not Adequately Controlled on Statin Therapytreatment3completed
NCT00777517
Bioequivalence Study On Pediatric Appropriate Formulationother1completed
NCT00271817
To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With Type IIa or Type IIb Hyperlipidemia (0653A-091)(COMPLETED)treatment3completed
NCT01321034
Effect of Niacin in the Lipoprotein (a) Concentrationtreatment4completed
NCT02689934
Efficacy of a Red Yeast Rice Based Nutraceutical Plus Probiotic in Patients With Moderate HypercholesterolemiaNo drug interventionstreatmentNot Availablecompleted
NCT00005134
Strong Heart StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00157924
Ezetimibe (+) Simvastatin vs. Atorvastatin Comparative Study in DM or Metabolic Syndrome Patients (0653A-093)treatment4completed
NCT01604824
A Study of Alirocumab in Participants With Autosomal Dominant Hypercholesterolemia (ADH) and Gain-of-Function Mutations (GOFm) of the Proprotein Convertase Subtilisin Kexin 9 (PCSK9) Gene or Loss-of-Function Mutations (LOFm) of the Apolipoprotein (Apo) B Genetreatment2completed
NCT02091024
Blood Lipid-lowering Effect of Brown Alga Ecklonia CavaNo drug interventionssupportive_care2 / 3completed
NCT02065024
Food Matrix and Genetic Variability as Determinants of Bioavailability and Biological Effects of Beta-cryptoxanthin and PhytosterolsNo drug interventionsbasic_science1completed
NCT00525824
12-week Open-label, Phase IIIb Comparing Efficacy and Safety of Rosuvastatin (CRESTOR™) in Combination With Ezetimibetreatment3completed
NCT02341924
Validating the "Foods for Health" Portfolio of Functional Food ProductsNo drug interventionsotherNot Availablecompleted
NCT00802516
Long Term Effects of Plant Sterol and Stanol EstersNo drug interventionsbasic_scienceNot Availablecompleted
NCT03916016
Sí Texas Hope Family Health CenterNo drug interventionstreatmentNot Availablecompleted
NCT02518516
High Potency Statins and Acute Kidney InjuryNot AvailableNot Availablecompleted
NCT02392416
Atorvastatin Study in Cardiovascular Disease RiskNo drug interventionsNot AvailableNot Availablecompleted
NCT02765516
Genetic Basis for Prediction of Non-responders to Dietary Plant Sterol InterventionNo drug interventionspreventionNot Availableterminated
NCT00256516
Low Carbohydrate Portfolio or "Eco-Atkins" DietNo drug interventionstreatment2completed
NCT00653796
Ezetimibe Plus Atorvastatin Versus Atorvastatin in Untreated Subjects With High Cholesterol (P03434)treatment4completed
NCT04596358
Interplay Between Adherence to the Mediterranean Diet, Lipid Profile and Blood Pressure: a Comparative Survey Among Healthcare and Non-Healthcare Female WorkersNo drug interventionsNot AvailableNot Availablecompleted
NCT06368258
Middle Term Effect of Red Yeast Rice on Plasma Lipids and Proteoma in Individuals With Suboptimal CholesterolemiaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03379558
Praluent® (Alirocumab) Pregnancy Exposure Registry: An OTIS Pregnancy Surveillance StudyNot AvailableNot Availableterminated
NCT00532558
Efficacy of Lapaquistat Acetate on Blood Cholesterol Levels in Treating Subjects With Hypercholesterolemiatreatment3terminated
NCT00276458
To Evaluate Ezetimibe Plus Atorvastatin Versus Atorvastatin in Patients With High Cholesterol Not Controlled on Atorvastatin 20 mg (0653-079)(COMPLETED)treatment3completed
NCT01723735
Effect of Alirocumab (SAR236553/REGN727) Administered on Top of Ezetimibe or Fenofibrate on Lipid Profiles in Healthy Subjectsbasic_science1completed
NCT04677335
Combination of AB-LIFE Probiotic Plus Monacolin K to Reduce Blood CholesterolNo drug interventionstreatmentNot Availablecompleted
NCT00005463
Population-Based Modeling of Cholesterol Lowering in the United StatesNo drug interventionsNot AvailableNot Availablecompleted
NCT04545463
Hypocholesterolemic Effect of FibracepNo drug interventionstreatmentNot Availablecompleted
NCT00783263
A Study of Ezetimibe Added On to Rosuvastatin Versus Up Titration of Rosuvastatin in Patients With Hypercholesterolemia (MK0653-139)treatment3completed
NCT00650663
Ezetimibe Plus Simvastatin Versus Simvastatin Alone in African-American Subjects With Primary Hypercholesterolemia (P03377)treatment4completed
NCT01365663
Multiple Ascending Dose Study of SPC4955 in Healthy SubjectsNo drug interventionstreatment1completed
NCT02289963
Evaluation of Alirocumab in Addition to Lipid-Modifying Therapy in Patients With High Cardiovascular Risk and Hypercholesterolemia in South Korea and Taiwantreatment3completed
NCT01314586
Flax Lignans and Heart HealthNo drug interventionspreventionNot Availablecompleted
NCT05266586
Study to Evaluate the Effect of Obicetrapib in Combination With Ezetimibe as an Adjunct to HIS Therapytreatment2completed
NCT01035086
Intervention With Lupin Kernel Fibre in Hypercholesterolemic SubjectsNo drug interventionspreventionNot Availablecompleted
NCT06297239
Argentine Registry of Lp(a)No drug interventionsNot AvailableNot Availablerecruiting
NCT01173939
Primary Prevention of Major Adverse Cardiac Events (MACE) With Standard and Intensive Statin Treatment in Patients With Diabetes: Survival and Cardiovascular Event AssessmentspreventionNot Availableterminated
NCT00270439
Omentectomy for the Treatment of Diabetes Mellitus Type 2No drug interventionstreatment1completed
NCT05457439
Sustainable-psycho-nutritional Intervention Program and Its Effects on Health Outcomes and the EnvironmentNo drug interventionspreventionNot Availableactive_not_recruiting
NCT02306122
Pharmacy Home Adherence Reporting and Monitoring Outcomes StudyNo drug interventionshealth_services_researchNot Availablecompleted
NCT01813422
GLobal Assessment of Plaque reGression With a PCSK9 antibOdy as Measured by intraVascular Ultrasoundtreatment3completed
NCT04997122
Health Effects of Consuming Olive Pomace OilNo drug interventionsbasic_scienceNot Availablecompleted
NCT01475825
A Study of the Safety and Efficacy of Two Different Regimens of Mipomersen in Patients With Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein Cholesteroltreatment3completed
NCT05733325
Diet-induced Elevations in LDL-C and Progression of AtherosclerosisNo drug interventionsNot AvailableNot Availablecompleted
NCT00092625
Co-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-803)treatment3completed
NCT01071525
The Effect of Niacin Administration on Oxidative Stress in Patients With Hypercholesterolmia, as Measured by the Use of a Novel Biomarkertreatment3unknown_status
NCT00966225
LIP-01 in HypercholesterolemiaNo drug interventionstreatment1completed
NCT02216825
Effect of L. Reuteri NCIMB 30242 on Plasma Bile Acid ProfileNo drug interventionsNot Available2completed
NCT03074630
Dapagliflozin and Cholesterol Metabolism in Type 2 Diabetes (DM2)basic_science4completed
NCT02827630
Proteus Discover in Subjects With Uncontrolled Hypertension and Type 2 DiabetesNo drug interventionstreatmentNot Availablecompleted
NCT00767130
DNA Diagnostic System for Statin Safety and EfficacyNo drug interventionsNot AvailableNot Availableunknown_status
NCT01227330
Pilot Program to Improve Statin Adherence and Lower Cholesterol in Older AdultsNo drug interventionstreatment1 / 2completed
NCT03110848
Effects of Atorvastatin in Graves' Orbitopathy (GO)treatment2completed
NCT01103648
Effect of Simvastatin and Ezetimibe on Lipid and InflammationtreatmentNot Availablecompleted
NCT06403748
Effect of a Dietary Supplement on Lipid Pattern, Indexes of NAFLD and Systemic Inflammation in Healthy Subjects With Suboptimal LDL-C LevelsNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04118348
Evaluating the Efficacy of Pediatric Lipid Screening AlertsNo drug interventionsscreeningNot Availablecompleted
NCT02748057
A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-833)treatment3completed
NCT00092157
Effectiveness of Two Approved Drugs in Lowering High Cholesterol (0733-224)treatment3completed
NCT04765657
Study of Efficacy and Safety of Inclisiran in Asian Participants With Atherosclerotic Cardiovascular Disease (ASCVD) or ASCVD High Risk and Elevated Low Density Lipoprotein Cholesterol (LDL-C)treatment3active_not_recruiting
NCT03881657
Reverse Colocated Integrated Care Intervention Among Persons With Severe Persistent Mental Illness at US-Mexico BorderNo drug interventionstreatmentNot Availablecompleted
NCT04921657
Genome-wide Analysis of Lipid-lowering Efficacy and Drug Level of Simvastatin and RosuvastatinNot AvailableNot Availablecompleted
NCT00005257
Diet and Plasma Cholesterol - Secular Trend AnalysisNo drug interventionsNot AvailableNot Availablecompleted
NCT02715726
Evaluation of Alirocumab Versus Ezetimibe on Top of Statin in Asia in High Cardiovascular Risk Patients With Hypercholesterolemiatreatment3completed
NCT00397826
Evaluation of the Effects of Simvastatin 40mgtreatment4completed
NCT05261126
A Study of the Efficacy and Safety of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-008)No drug interventionstreatment2completed
NCT00549926
Yokohama Assessment of Fluvastatin, Pravastatin, Pitavastatin and Atorvastatin in Acute Coronary Syndrome (Yokohama-ACS)treatment4completed
NCT02481466
The Combined Portfolio Diet and Exercise StudyNo drug interventionstreatmentNot Availablecompleted
NCT00718965
Evaluation of Efficacy and Safety of AVE5530 in Patients With Primary HypercholesterolemiaNo drug interventionstreatment3terminated
NCT00653965
Treatment of Hypercholesterolaemia in Hispanic Subjects (STARSHIP)treatment3completed
NCT01053065
The Multicenter Atorvastatin Plaque Stabilization (MAPS) Studybasic_scienceNot Availablecompleted
NCT00220974
Study to Assess if Internet-Based Tailored Advice Could Modify Behaviour to Improve HealthNo drug interventionsNot AvailableNot Availablecompleted
NCT03949374
Clinical Trial to Evaluate Efficacy and Safety of ROVASRO 10mg Versus CRESTOR 10mg in Hypercholesterolemic Patientstreatment4completed
NCT00826774
Improving the Management of Obesity in Primary Care Practice (The Power-UP Trial)No drug interventionstreatment3completed
NCT00651274
Comparison of Co-administration of Ezetimibe Plus Simvastatin Versus Simvastatin Alone in Primary Hypercholesterolemia (P03476)treatment4completed
NCT03543774
Lipid-lowering Therapies in Vietnamese Chronic Kidney Disease Populationtreatment4unknown_status
NCT03847974
Open-Label Extension to Evaluate the Longer Term Efficacy and Safety of LIB003treatment2completed
NCT01353820
Effects of Lactobacillus Delbruckii Lactis DN111244 Fermented Milk Consumption on Plasma Lipids Levels in Hypercholesterolaemic AdultsNo drug interventionsbasic_scienceNot Availablecompleted
NCT01600820
Effect of the Consumption of a Fermented Milk Enriched With Plant Sterols (Spain)No drug interventionsNot AvailableNot Availablecompleted
NCT00546182
Simvastatin Reduces Adiponectin Levels and Insulin SensitivityNo drug interventionsNot AvailableNot Availablecompleted
NCT01222182
Statin Interchange by Pharmacist Collaborative Practice Agreement (CPA)Not AvailableNot Availablecompleted
NCT00574782
Evaluation of the Efficacy of Rosuvastatin in Daily Practice in Untreated High Risk Patients (CHALLENGE)No drug interventionsNot AvailableNot Availablecompleted
NCT05393882
Impact of Cholesterol Level on Long-term Coronary Bypass Graft PatencyNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01161082
Ascending Multi-dose Study of REGN727(SAR236553) With and Without Concomitant Atorvastatintreatment1completed
NCT05730231
Clinical Trials of Effects of Time Restricted Eating on Health Parameters in AdultsNo drug interventionspreventionNot Availableactive_not_recruiting
NCT00454831
Efficacy and Safety of HEP-40 Chitosan for Mild to Moderately Elevated CholesterolNo drug interventionstreatment2completed
NCT00395473
Ezetimibe Added to Statin Therapy (EASY) Study (0653-087)(COMPLETED)treatment3completed
NCT01705873
Analysis on the Risk of Cardiovascular Events in HIV- Infected Subjects Treated With LPV/r Based HAART Regimen vs. an EFV Based RegimenNo drug interventionsNot AvailableNot Availableunknown_status
NCT00654173
Comparing the Efficacy and Safety of Rosuvastatin With Atorvastatin and Simvastatin (SOLAR)treatment3completed
NCT00479973
The Anti-Diabetic and Cholesterol-Lowering Effects of Cinnamon and Cassia BarkNo drug interventionstreatment2unknown_status
NCT00409773
Ezetimibe/Simvastatin in Patients With Metabolic Syndrome (0653A-107)(COMPLETED)treatment3completed
NCT00944827
Combination Treatment With Green Tea Extract and Statins in Patients With HypercholesterolemiaNo drug interventionssupportive_care2completed
NCT03161327
Digital Ankle Brachial Index (ABI) as a Screening Tool in Detecting Peripheral Arterial DiseaseNo drug interventionspreventionNot Availablecompleted
NCT00955227
Can Cholesterol Lowering Drugs Influence Circulating Omega-3 Fatty Acid LevelsNot AvailableNot Availablecompleted
NCT00701727
Ezetimibe Reverse Cholesterol Transport (RCT) Pilot Studytreatment4completed
NCT03768427
Ezetimibe (EZ)/Atorvastatin (Ator) (MK-0653C) vs. Ator in Chinese Hypercholesterolemic Participants (MK-0653C-439)treatment3completed
NCT00729027
Evaluation of Safety and Efficacy of AVE5530 as add-on to Ongoing Statins in Patients With Primary HypercholesterolemiaNo drug interventionstreatment3terminated
NCT00203476
A Prospective, Open Label Comparison of Ezetimibe, Niacin, and Colestipol as Adjunct Therapy in Lipid Reductiontreatment4completed
NCT00833976
Omega-3 Fatty Acids (Lovaza) for Second Generation Antipsychotic-Associated Hypertriglyceridemiatreatment4completed
NCT02603276
Lipid-lowering Effect of Phytosterols, Red Yeast Rice and Their CombinationNo drug interventionstreatmentNot Availablecompleted
NCT05762276
A Study to Investigate the Safety, Tolerability, Immunogenicity, and Pharmacodynamics of VXX-401 Administered IM in Adult ParticipantsNo drug interventionstreatment1active_not_recruiting
NCT03470376
NUtraceutical TReatment for hYpercholesterolemia in HIV-infected PatientsNo drug interventionstreatment4completed
NCT01912560
Pilot Study To Assess CAT-2003 in Patients With HyperlipidemiaNo drug interventionstreatment2completed
NCT00092560
Two Investigational Drugs in Patients With Mixed Hyperlipidemia (0653-036)treatment3completed
NCT00398294
To Evaluate the Lipid-Lowering Efficacy and Safety of Simvastatin 40 Mg Tablet In Patients With Hypercholesterolemia (0733-264)treatment4completed
NCT01954394
Open Label Study of Long Term Safety Evaluation of Alirocumabtreatment3completed
NCT02749994
A Clinical Trial to Compare the Efficacy and Safety of a Combination Therapy of Ezetimibe and Rosuvastatin Versus Monotherapy of Rosuvastatin in Hypercholesterolemia Patients (I-ROSETTE Study)treatment3completed
NCT02694094
Impact of Ketogenic Diets on Cardiovascular Health in Adults With EpilepsyNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT06492291
Open-label Extension Study of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-019) CORALreef ExtensionNo drug interventionstreatment3recruiting
NCT00114491
Rosuvastatin Affecting Aortic Valve EndotheliumNot AvailableNot Availablecompleted
NCT00325780
Long-Term Extension Study of Pitavastatin in Patients With Primary Hypercholesterolemia or Combined Dyslipidemiatreatment3completed
NCT00133380
A Study in People With High Cholesteroltreatment2completed
NCT01043380
Plaque REgression With Cholesterol Absorption Inhibitor or Synthesis Inhibitor Evaluated by IntraVascular UltraSoundtreatment4completed
NCT00388180
An Exploratory Study To Look At The Effect Of Two Investigational Drugs On Body Fat And InflammationNot AvailableNot Availablecompleted
NCT04271280
Treatment of High and Very High riSk Dyslipidemic pAtients for the PreveNTion of CardiOvasculaR EventsNo drug interventionsNot AvailableNot Availablecompleted
NCT00267280
A Clinical Trial Comparing Torcetrapib/Atorvastatin To Simvastatin In Subjects With High Cholesterol (A5091031).treatment3terminated
NCT00362180
Measure Liver Fat Content After ISIS 301012 (Mipomersen) Administrationtreatment2completed
NCT05398029
A Study of VERVE-101 in Patients With Familial Hypercholesterolemia and Cardiovascular DiseaseNo drug interventionstreatment1active_not_recruiting
NCT00972829
Tolerability and Lipid Lowering Effect of Weekly/Biweekly Crestor in Statin Intolerant Patients Treated With Zetiatreatment4unknown_status
NCT01860729
A Study of the Safety and Efficacy of Anacetrapib (MK-0859) Among Participants With Hypercholesterolemia When Added to Ongoing Statin Therapy (MK-0859-022)treatment3completed
NCT00762229
Evaluation of LDL Cholesterol in Patients Switched From 10 to 5 Milligrams of Zetia (Ezetimibe)health_services_researchNot Availablecompleted
NCT01785329
Pharmacokinetic of Alirocumab SAR236553 (REGN727) Administered Subcutaneously at 3 Different Injection Sites in Healthy Subjectsbasic_science1completed
NCT01478789
Efficacy of Plant Sterol-Fortified Dairy Product on Plasma Lipid and Plant Sterol Concentrations in HumansNo drug interventionstreatmentNot Availablecompleted
NCT04770389
Randomized Study of Obicetrapib in Combination With Ezetimibetreatment2completed
NCT02011789
Metabolism And Health Effects Of Citrus Limonoids in Hypercholesterolemic HumansNo drug interventionsbasic_scienceNot Availablecompleted
NCT01304992
Cholesterol-lowering Effects of Lupin ProteinNo drug interventionspreventionNot Availablecompleted
NCT00565292
A Study of MK0859 in Patients With Primary Hypercholesterolemia or Mixed Hyperlipidemia (MK-0859-011)(COMPLETED)treatment1completed
NCT01414192
A Study to Design a Model Cohort for Analysis of Dyslipidemia (MK-0653A-204)No drug interventionsNot AvailableNot Availablecompleted
NCT03882892
Long-Term Safety and Tolerability of Ezetimibe (SCH 58235, MK-0653) With Atovastatin (P02154, MK-0653-017)treatment3completed
NCT00242944
Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome (JAPAN-ACS)treatment4completed
NCT00651144
Assessment of Potential Interaction Between Ezetimibe and Rosuvastatin in Healthy Subjects With High Cholesterol (P03317)treatment1completed
NCT00652444
Effect Of Ezetimibe Coadministration With Simvastatin In A Middle Eastern Population: A Prospective, Multicentre, Randomized, Double-Blind, Placebo-Controlled Trial (0653-151)treatment4completed
NCT06355544
Individual Factors Related to Chronic Low-grade Inflammation and Cardiometabolic Disease RiskNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05064644
Lipid Lowering Effect of Plant Stanol Ester in a Spoonable Non-dairy ProductNo drug interventionstreatmentNot Availablecompleted
NCT02772640
Effectiveness of Treatment of Hypercholesterolemia With Rosuvastatin and Ezetimibetreatment4completed
NCT00474240
AEGR-733 and Atorvastatin 20 mg vs. Monotherapy in Moderate Hypercholesterolemiatreatment2completed
NCT01730040
Study of the Efficacy and Safety of Alirocumab (REGN727/SAR236553) in Combination With Other Lipid-modifying Treatment (LMT) (ODYSSEY OPTIONS I)treatment3completed
NCT03175367
Study of Evinacumab (REGN1500) in Participants With Persistent Hypercholesterolemiatreatment2completed
NCT01890967
A Study of LY3015014 in Participants With High Cholesteroltreatment2completed
NCT00046267
Niacin for Treatment of Elevated Cholesterol and Triglycerides in HIV-Infected PatientstreatmentNot Availablecompleted
NCT01071967
Effect of a Community-based Nursing Intervention on Mortality in Chronically Ill Older AdultsNo drug interventionspreventionNot Availableunknown_status
NCT04579367
Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed DyslipidemiaNot AvailableNot Availablerecruiting
NCT00405067
The Safety & Efficacy of Combination BMS-201038 (AEGR-733) & Ezetimibe vs. Monotherapy in Moderate Hypercholesterolemiatreatment2completed
NCT04147767
Plant Sterol INtervention for Cancer Prevention (PINC)No drug interventionspreventionNot Availableunknown_status
NCT01569867
Genetic Influences on Statin Blood Concentrations in African AmericansNo drug interventionsNot AvailableNot Availablecompleted
NCT02391701
Effect of an Atlantic Diet on Anthropometric Indices and Serum Lipid ProfileNo drug interventionstreatmentNot Availablecompleted
NCT00621101
Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjectsbasic_science1completed
NCT06568601
Pharmacogenomic Informed Statin PrescribingNo drug interventionshealth_services_researchNot Availablenot_yet_recruiting
NCT01524601
The Rosuvastatin In TrAnsplant Recipients Studytreatment4completed
NCT00404001
Study of Oral MD-0727 Administered to Patients With Primary Hypercholesterolemiatreatment2completed
NCT00466401
Effect of Ezetimibe on Platelet Aggregation and LDL Tendency to Peroxidationtreatment4completed
NCT02584504
Efficacy and Safety of Alirocumab in Patients With Hypercholesterolemia Not Adequately Controlled With Non-statin Lipid Modifying Therapy or the Lowest Strength of Statintreatment3completed
NCT00651404
Ezetimibe Plus Atorvastatin Versus Atorvastatin Alone in Subjects With Primary Hypercholesterolemia (Study P03406)treatment3completed
NCT01448304
Study of the Tolerability, Safety, Pharmacokinetics and Pharmacodynamics of Alirocumab SAR236553 (REGN727)treatment1completed
NCT00758004
Bioequivalence Study Of Pediatric Appropriate Formulationother1completed
NCT00166504
Ezetimibe Plus (+) Simvastatin Versus Atorvastatin Comparative Study (0653A-092)(COMPLETED)treatment4completed
NCT00202904
Effectiveness and Safety of Ezetimibe Added to Atorvastatin in Patients With High Cholesterol and Coronary Heart Disease (Study P03740)treatment4completed
NCT05218304
Baromètre Santé Adulte 2021-2022No drug interventionsotherNot Availablesuspended
NCT02835872
A Study to Evaluate the Effects of Dietary Fiber on Blood Lipids in Men and WomenNo drug interventionsbasic_scienceNot Availablecompleted
NCT05858372
Effects of Chios Mastiha Essential Oil on Cholesterol Levels of Healthy VolunteersNo drug interventionstreatmentNot Availablecompleted
NCT00001368
Potential Risk Factors for StrokeNo drug interventionstreatment1completed
NCT02955368
Clinical Trial to Evaluate the Efficacy and Safety of DP-R212No drug interventionstreatment3withdrawn
NCT03480568
Alirocumab in Patients on a Stable Dialysis Regimentreatment3unknown_status
NCT00329069
The Role of Atorvastatin on Monocyte Function in Patients With Coronary Artery Disease and HypercholesterolemiadiagnosticNot Availablecompleted
NCT05438069
German Inclisiran Network: Retrospective Registry of Patients Being Treated With the siRNA Inclisiran in GermanyNo drug interventionsNot AvailableNot Availablerecruiting
NCT00664469
INdians Followed for INtensive Lipid Lowering Treatment and Its safetYtreatment3terminated
NCT00466869
A Randomized, Double-Blind, Placebo-Controlled Study to Examine the Effect of Betahistine on Plasma Lipids in Patients Treated With Simvastatintreatment2terminated
NCT05952869
A Study of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017) CORALreef HeFHNo drug interventionstreatment3active_not_recruiting
NCT05221346
Effect of Oleactiv® on LDL OxidabilityNo drug interventionspreventionNot Availablecompleted
NCT04164446
Supplementation of Oil Palm Phenolics to Healthy ParticipantsNo drug interventionsprevention1unknown_status
NCT05901246
Anti-eryptotic Effect of a Food Supplement With Plants Sterols in Hypercholesterolemia Treated With StatinsNo drug interventionsbasic_scienceNot Availableactive_not_recruiting
NCT00530946
A Randomized Study To Evaluate Efficacy And Safety Of A Fixed Combination Therapy Of Amlodipine And Atorvastatintreatment3completed
NCT00092846
A 6-Month Consumer Behavior Study of a Self-Management System (0803-084)(COMPLETED)prevention3completed
NCT00249912
Efficacy of Lapaquistat Acetate Alone or Combined With Rosuvastatin in Subjects With Hypercholesterolemiatreatment3completed
NCT04402112
Efficacy and Safety of Pitavastatin in a Real-world SettingNot AvailableNot Availablecompleted
NCT03815812
Multiple Ascending Dose Study of PCSK-9 Inhibitor (IBI306) in Chinese Patients With Hypercholesterolemiatreatment2completed
NCT03427710
A First In Human Study to Assess CiVi007 in Subjects With an Elevated LDL-Cholesterol LevelNo drug interventionstreatment1completed
NCT00005210
Sex Steroids, Obesity and Lipids in Adolescent FemalesNo drug interventionsNot AvailableNot Availablecompleted
NCT05923281
A Phase III Confirmatory Study of K-877 (Pemafibrate) in Patients With Hypercholesterolemia and Statin Intolerancetreatment3recruiting
NCT02585895
Evolocumab Compared to LDL-C Apheresis in Patients Receiving LDL-C Apheresis Prior to Study Enrollmenttreatment3completed
NCT01185795
Efficacy of Cardioviva™ Probiotic Yogurt FormulationNo drug interventionstreatment2completed
NCT04998695
Health Effects of Consuming Olive Pomace OilNo drug interventionsbasic_scienceNot Availablecompleted
NCT02609295
Effects of α-linolenic Acid Supplementation on Hemostasis in Nondiabetic and Hypercholesterolemic SubjectsNo drug interventionsprevention3completed
NCT00005495
Primary Prevention of CHD Risk Factors Occurring in USNo drug interventionsNot AvailableNot Availablecompleted
NCT00651014
Ezetimibe Plus Simvastatin Versus Simvastatin in Patients With Hypercholesterolemia and Coronary Risk Factors (P03405)treatment4terminated
NCT02579655
Assessing Outcomes of Enhanced Chronic Disease Care Through Patient Education and a Value-based Formulary StudyNo drug interventionspreventionNot Availablecompleted
NCT05265455
Diet and Plant Sterols in the Control of Cholesterolemia (DESCO)No drug interventionstreatmentNot Availablecompleted
NCT02681055
Open-Label Study To Evaluate MN-001 on HDL & Triglyceride in NASH & NAFLD Subjectstreatment2completed
NCT01243255
Polish Survey on the Efficacy of the Hypercholesterolemia TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT03392350
Randomized Trial of the Impact of Body Scanning and Intensive Behavioral Intervention on Behavioral Change and Health OutcomesNo drug interventionspreventionNot Availablecompleted
NCT05082350
Nutritional Intervention With Black GarlicNo drug interventionspreventionNot Availableunknown_status
NCT00653523
Coadministration of Ezetimibe and Simvastatin in Patients With Primary Hypercholesterolemia (P05457)treatment3completed
NCT00173823
Malnutrition and Inflammation in Dialysis Patients in TaiwanNo drug interventionsNot AvailableNot Availableunknown_status
NCT02667223
Pharmacokinetic and Pharmacodynamic Study of Bococizumab Alone and When Combined With Recombinant Human Hyaluronidasebasic_science1terminated
NCT03428308
Detection and Treatment of Somatic Disease in Patients With Severe Mental DiseaseNo drug interventionsscreeningNot Availableunknown_status
NCT05460208
Hypocholesterolemic Effect of a Phytosterol-enriched Spreadable Cream Prepared With Virgin Olive OilNo drug interventionstreatmentNot Availablecompleted
NCT00334308
Barley Protein and CVDNo drug interventionstreatment2completed
NCT01466608
Influence of OATP1B1 and BRCP Genotype on Rosuvastatin PK, PD and Lipidomics in Hyperlipidemic Patientstreatment4completed
NCT01245738
Effect of Statins on Lipid Levels Following the First Acute Coronary Event (MK-0000-204)No drug interventionsNot AvailableNot Availablecompleted
NCT02955238
Latinos Understanding the Need for AdherenceNo drug interventionstreatmentNot Availablecompleted
NCT03631238
The Dual Impact of Homocysteine and Cholesterol on Cognitive FunctionsNo drug interventionsNot AvailableNot Availablecompleted
NCT00309738
Study to Compare the Efficacy and Safety of Pitavastatin and Simvastatintreatment3completed
NCT01163838
Multiple-Dose Safety Study Of RN316 For TheTreatment Of HypercholesterolemiaNo drug interventionstreatment1withdrawn
NCT00864643
Efficacy and Safety of Lapaquistat Acetate Coadministered With Atorvastatin in Subjects With Hypercholesterolemiatreatment2completed
NCT01352897
Registry On Efficacy and Safety Of Rosuvastatin, and Atorvastatin and Simvastatin In HypercholesterolaemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT02585778
Efficacy and Safety of Alirocumab Versus Placebo on Top of Maximally Tolerated Lipid Lowering Therapy in Patients With Hypercholesterolemia Who Have Type 1 or Type 2 Diabetes and Are Treated With Insulin (ODYSSEY DM - Insulin)treatment3completed
NCT03415178
Usability Study of the Commercial Auto-injector Device and the New Auto-injector Device (SYDNEY) in Patients With High or Very High CV Risk With Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapytreatment3completed
NCT01597700
Acotral® Versus Zetia® Ezetimibe Bioequivalance Study.other1completed
NCT01711749
Rosuvastatin Calcium Bioequivalence Study - Fastother1completed
NCT02906124
Study to Evaluate the Safety of Repatha® in PregnancyNo drug interventionsNot AvailableNot Availableterminated
NCT00163163
Carotid Atorvastatin Study in Hyperlipidemic Post-Menopausal WomenNo drug interventionstreatment3completed
NCT02770131
Chart Review of Repatha® in Subjects With HyperlipidaemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT00329173
PULSAR - A Prospective Study to Evaluate the Utility of Low Doses of the Statins Atorvastatin and Rosuvastatin.treatment3completed
NCT00427960
Study of Asian Patients With Hypercholesterolaemia in the UK - Rosuvastatin 5mg Versus Atorvastatin 10mgtreatment4terminated
NCT02065180
The Effect of a Red Rice and Olive Extract Nutrition Supplement on Cholesterol Levels in Patients With Metabolic SyndromeNo drug interventionstreatment4completed
NCT05934292
Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Renal Impairment Study 2 (MK-0616-020)No drug interventionstreatment1completed
NCT01354340
Dose Effect of Limicol on (LDL)-Cholesterol LevelsNo drug interventionstreatmentNot Availablecompleted
NCT01617655
Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia (ODYSSEY HIGH FH)treatment3completed
NCT00654303
OLE Study to Evaluate Safety / Efficacy of ZD4522treatment3completed
NCT03510884
An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemiatreatment3completed
NCT01779687
Pharmacokinetic Drug Interaction Study Between Raltegravir and Atorvastatin.other1completed
NCT01257971
Non-interventional Study (NIS) to Assess Reaching of Cholesterol Target Values in Patients Treated With HMG-CoA Reductase InhibitorsNo drug interventionsNot AvailableNot Availablecompleted
NCT06008756
Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef OutcomesNo drug interventionstreatment3recruiting
NCT04058834
A Research Study Investigating How NNC0385-0434 is Tolerated in People With or Without High Cholesterol LevelsNo drug interventionstreatment1completed
NCT06275724
Specified Drug-use Survey of Leqvio for s.c. Injection.No drug interventionsNot AvailableNot Availablerecruiting
NCT00653835
Ezetimibe Plus Simvastatin Versus Simvastatin in Untreated Subjects With High Cholesterol (P03435)treatment4completed
NCT04169386
A Study of PCSK9 Inhibitor AK102 in Healthy SubjectsNo drug interventionstreatment1completed
NCT00695539
Rosuvastatin Efficacy and Safety Evaluation in Hypercholesterolaemic PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01935674
Treatment With Rosuvastatin Versus Switching PI (Protease Inhibitor) in Patients HIV With High Cholesterol Levelstreatment4completed
NCT02890992
An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemiatreatment2completed
NCT01483950
Evaluation of Patients Treated With HMG-CoA Reductase Inhibitors to Reach Cholesterol Target ValuesNo drug interventionsNot AvailableNot Availablecompleted
NCT00328523
TWICE (Ezetimibe Together With Any Statin Cholesterol Enhancement)(0653-060)treatment3completed
NCT06501443
LATAM LOWERS LDL-Ctreatment4not_yet_recruiting
NCT00376584
Effect of an Investigational Compound on Tolerability of Extended Release Niacin (0524A-023)(COMPLETED)treatment3completed
NCT05164185
The Effect of Remote Ischemic Conditioning in Patients With HypercholesterolemiaNo drug interventionsbasic_scienceNot Availablecompleted
NCT00347217
Observational to Investigate the Efficacy of CRESTOR 5mg in Reaching LDL-C Target Goals in Patients Who Are at High Risk for a Cardiovascular EventNo drug interventionsNot AvailableNot Availablecompleted
NCT02850224
Pediatric Preventative Health Screenings - Obesity and Family-Centered OutcomesNo drug interventionshealth_services_researchNot Availablecompleted
NCT00239330
Direct Statin Comparison of LDL-C Values: an Evaluation of Rosuvastatin Therapytreatment3completed
NCT00408382
Lipitor Phase 4 Clinical Trial in Hypercholesteremia Patients With Yellow Coronary Plaquetreatment4completed
NCT00225589
A Study Measuring Effects on Intima Media Thickness: An Evaluation of Rosuvastatin 40 mg (METEOR)Not Available3completed
NCT01477944
Pattern of Statins Use in CataloniaNo drug interventionsNot AvailableNot Availablecompleted
NCT02722408
Efficacy and Safety of Gemcabene in Patients With Homozygous Familial Hypercholesterolemia on Stable, Lipid-Lowering Therapy (COBALT-1)treatment2completed
NCT00153738
Phytosterol Supplementation and Cardiovascular RiskNo drug interventionspreventionNot Availablecompleted
NCT00688454
C-Control: Efficacy and Safety of Therapy With Rosuvastatin in Statin-Naive and in Statin-Switched PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT02634151
A 12-Week, Phase 2 Study of Gemcabene in Hypercholesterolemia Patients on Stable Moderate and High-Intensity Statinstreatment2completed
NCT03634436
The PK/PD Study of A Single Subcutaneous Injection of SHR-1209 in Healthy Subjectstreatment1completed
NCT02587416
Effect of Gemcabene on the Pharmacokinetics of Atorvastatin in Healthy Volunteersbasic_science1completed
NCT01354327
Effects of Limicol on LDL-cholesterolNo drug interventionstreatmentNot Availablecompleted
NCT00329160
Rosuvastatin in the Long-term Treatment of Hypercholesterolaemic Subjects With Coronary Heart Diseasetreatment4completed
NCT01890889
Study of Changes in Total Cholesterol Levels as a Function of Consuming a Supplement Designed to Improve Cardiovascular HealthNo drug interventionsNot AvailableNot Availableunknown_status
NCT01614561
An Observational Study Evaluating Cholesterol Levels in Patients on Cholesterol Lowering Drugs in Jordan and LebanonNo drug interventionsNot AvailableNot Availablecompleted
NCT04154579
Arts & Health Education to Improve Health, Resilience, and Well-BeingNo drug interventionstreatmentNot Availableterminated
NCT06227819
BVA-200 vs BVA-100 Validation StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT06350604
Project WHADE: A Partner-Based Physical Activity Program for WomenNo drug interventionspreventionNot Availablerecruiting
NCT00965055
Ezetimibe in Patients Hypo-responsive to Statinstreatment3terminated
NCT04317690
Online Trial Examining Validity and Reliability of the Shared Decision Making Process SurveyNo drug interventionsNot AvailableNot Availablecompleted
NCT06192251
Complete Lifestyle Medicine Intervention ProgramNo drug interventionsNot AvailableNot Availablerecruiting
NCT04787978
Creating Healthier Communities Through Meaningful Partnerships: A Model From the National African American Male Wellness Initiative - OSU PartnershipNo drug interventionspreventionNot Availablecompleted
NCT00510809
Effect of Policosanol as Monotherapy and Adjunctive to Statin TherapytreatmentNot Availablecompleted
NCT01187056
The RISAP-study: a Complex Intervention in Risk Communication and Shared Decision-making in General PracticeNo drug interventionspreventionNot Availablecompleted
NCT01004237
Additive Effects of Pravastatin and Valsartantreatment4completed
NCT02133534
The Effect of Atorvastatin on Endothelial Cell Dysfunction in Chronic Kidney Diseasetreatment4terminated
NCT06364163
Effect of Herring Oil Concentrate on LDL Cholesterol Concentration in AdultsNo drug interventionsbasic_scienceNot Availablenot_yet_recruiting
NCT03084822
Cardiovascular Health Promotion Among African-Americans by FAITH!No drug interventionspreventionNot Availablecompleted
NCT05473325
Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY)No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04317274
Online Trial Examining Validity of the Shared Decision Making Process Survey With Video VignettesNo drug interventionsotherNot Availablecompleted
NCT03528031
Habitual Diet and Avocado TrialNo drug interventionspreventionNot Availablecompleted
NCT04510844
Evolocumab In Advanced Chronic Kidney Disease Trialtreatment4withdrawn
NCT04964544
Technology-Assisted Cholesterol Trial in Consumers (TACTiC)treatment3completed
NCT03542240
Effects of Curcumin Supplementation on Gut Barrier Function in Patients With Metabolic SyndromeNo drug interventionspreventionNot Availablecompleted