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Displaying results 7401 - 7410 of 10000 in total
  1. Target

    Somatostatin receptor type 4

    go.drugbank.com/bio_entities/BE0009273
    TargetHumans

    Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate re...

    Polypeptides: Somatostatin receptor type 4Synonyms: SS-4-R
  2. Target

    Phosphatidylinositol 4-kinase beta

    go.drugbank.com/bio_entities/BE0009513
    TargetHumans

    Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phospho...

    Polypeptides: Phosphatidylinositol 4-kinase betaSynonyms: PtdIns 4-kinase beta
  3. Target

    Delta-like protein 4

    go.drugbank.com/bio_entities/BE0010485
    TargetHumans

    Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313...

    Polypeptides: Delta-like protein 4Synonyms: Drosophila Delta homolog 4
  4. Target

    Melanoma-associated antigen 4

    go.drugbank.com/bio_entities/BE0010534
    TargetHumans

    Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase (PubMed:22842486). Also negatively regulates p53-mediated apoptosis (PubMed:22842486)

    Polypeptides: Melanoma-associated antigen 4Synonyms: MAGE-4 antigen
  5. Target

    Alpha-(1,3)-fucosyltransferase 4

    go.drugbank.com/bio_entities/BE0012925
    EnzymeHumans

    Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked … In a cell type specific manner, may also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE (PubMed:11278338, PubMed:1716630

    Polypeptides: Alpha-(1,3)-fucosyltransferase 4Synonyms: 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase, Fucosyltransferase 4
  6. Target

    Double homeobox protein 4

    go.drugbank.com/bio_entities/BE0020504
    TargetHumans

    Binds to double-stranded DNA elements with the consensus sequence 5'-TAATCTAATCA-3' (PubMed:28459454, PubMed:28459457, PubMed:29572508, PubMed:30315230, PubMed:30540931).

    Polypeptides: Double homeobox protein 4
  7. Drug

    Ethanol

    go.drugbank.com/drugs/DB00898
    ApprovedInvestigational

    A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. … It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.

    Mixtures: Adventure Medical Kits 1-4 Person First Aid, Anti-bacterial Hand Sanitizer 3 Pack 2Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
  8. Drug

    Racepinephrine

    go.drugbank.com/drugs/DB11124
    Approved

    Racepinephrine is a racemic mixture consisting of d-[DB00668] and l-[DB00668] enantiomers. Epinephrine is a non-selective α- and β-adrenergic receptor agonist. … It is a bronchodilator used in the temporary relief of mild symptoms of intermittent asthma including wheezing, tightness of chest and shortness of breath.

    Mixtures: Gingicord W/epineph and Alum Size 2, Gingicord W Epineph and Alum Size No 3Categories: Adrenergic beta-3 Receptor Agonists, Adrenergic alpha-2 Receptor Agonists
  9. Pathway

    Acylcarnitine (2E)-3-methylpent-2-enedioylcarnitine

    smpdb.ca/view/SMP0123331
    Metabolic

    (2E)-3-methylpent-2-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (2E)-3-methylpent-2-enedioyl-CoA reacts with L-carnitine to form (2E)-3-methylpent-2-enedioylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Carnitine O-palmitoyltransferase 2, mitochondrial
  10. Pathway

    Acylcarnitine (3E)-2-propylpent-3-enoylcarnitine

    smpdb.ca/view/SMP0123568
    Metabolic

    (3E)-2-propylpent-3-enoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (3E)-2-propylpent-3-enoyl-CoA reacts with L-carnitine to form (3E)-2-propylpent-3-enoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Carnitine O-palmitoyltransferase 2, mitochondrial