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Displaying results 8001 - 8010 of 10000 in total
  1. Target

    Monocarboxylate transporter 3

    go.drugbank.com/bio_entities/BE0000361
    TargetHumans

    Probable retinal pigment epithelium (RPE)-specific proton-coupled L-lactate transporter (By similarity). May facilitate transport of lactate and H(+) out of the retina and could therefore play a role in pH and ion homeostasis of the oute...

    Polypeptides: Monocarboxylate transporter 3Synonyms: MCT 3
  2. Target

    3-dehydroquinate synthase

    go.drugbank.com/bio_entities/BE0001691
    TargetStaphylococcus aureus (strain MRSA252)

    Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).

    Polypeptides: 3-dehydroquinate synthaseFunction: 3-dehydroquinate synthase activity
  3. Target

    3-dehydroquinate dehydratase

    go.drugbank.com/bio_entities/BE0001743
    TargetHelicobacter pylori (strain ATCC 700392 / 26695)

    Catalyzes a trans-dehydration via an enolate intermediate.

    Polypeptides: 3-dehydroquinate dehydrataseSynonyms: 3-dehydroquinase
  4. Target

    3-dehydroquinate dehydratase

    go.drugbank.com/bio_entities/BE0001857
    TargetMycobacterium tuberculosis

    Catalyzes a trans-dehydration via an enolate intermediate.

    Polypeptides: 3-dehydroquinate dehydrataseSynonyms: 3-dehydroquinase
  5. Target

    Histone deacetylase 3

    go.drugbank.com/bio_entities/BE0002367
    TargetHumans

    (2-hydroxyisobutyryl) and isonicotinyl acyl groups from lysine residues, leading to protein decrotonylation, delactylation, de-2-hydroxyisobutyrylation and deisonicotinylation, respectively (PubMed:28497810 … Contributes, together with XBP1 isoform 1, to the activation of NFE2L2-mediated HMOX1 transcription factor gene expression in a PI(3)K/mTORC2/Akt-dependent signaling pathway leading to endothelial cell

    Polypeptides: Histone deacetylase 3Synonyms: RPD3-2
  6. Target

    Melanocortin receptor 3

    go.drugbank.com/bio_entities/BE0009683
    TargetHumans

    G protein-coupled receptor for melanocyte-stimulating hormones (alpha, beta, and gamma-MSH) and corticotropin/ACTH, which are peptide products of the POMC precursor (PubMed:37524700, PubMed:8463333). Upon activation, couples to G(s) prot...

    Polypeptides: Melanocortin receptor 3
  7. Target

    Kynurenine 3-monooxygenase

    go.drugbank.com/bio_entities/BE0011714
    EnzymeHumans

    Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn) (PubMed:23575632, PubMed:26752518, PubMed:28604669, PubMed:29208702, PubMed:29429898).

    Polypeptides: Kynurenine 3-monooxygenaseSynonyms: Kynurenine 3-hydroxylase
  8. Target

    Dipeptidyl peptidase 3

    go.drugbank.com/bio_entities/BE0020247
    TargetHumans

    Cleaves and degrades bioactive peptides, including angiotensin, Leu-enkephalin and Met-enkephalin (PubMed:1515063, PubMed:3233187). Also cleaves Arg-Arg-beta-naphthylamide (in vitro) (PubMed:11209758, PubMed:3233187, PubMed:9425109)

    Polypeptides: Dipeptidyl peptidase 3
  9. Target

    Ketosamine-3-kinase

    go.drugbank.com/bio_entities/BE0023133
    EnzymeHumans

    Ketosamine-3-kinase involved in protein deglycation by mediating phosphorylation of ribuloselysine and psicoselysine on glycated proteins, to generate ribuloselysine-3 phosphate and psicoselysine-3 phosphate … Ribuloselysine-3 phosphate and psicoselysine-3 phosphate adducts are unstable and decompose under physiological conditions (PubMed:14633848, PubMed:15137908).

    Polypeptides: Ketosamine-3-kinaseSynonyms: Protein-psicosamine 3-kinase FN3KRP, Fructosamine-3-kinase-related protein
  10. Target

    Retinaldehyde dehydrogenase 3

    go.drugbank.com/bio_entities/BE0000583
    TargetHumans

    Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively (...

    Polypeptides: Retinaldehyde dehydrogenase 3Synonyms: RALDH-3