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Displaying results 831 - 840 of 10000 in total
  1. Drug

    Dorzolamide

    go.drugbank.com/drugs/DB00869
    ApprovedInvestigational

    [L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. … Dorzolamide is a non-bacteriostatic sulfonamide derivative [A1304] and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and

    Mixtures: DORZOLOL® UD, Van-dorzolamide-timololCategories: latanoprost and dorzolamide, Antiglaucoma Preparations and Miotics
  2. Pathway

    Valine, Leucine, and Isoleucine Degradation

    smpdb.ca/view/SMP0000032
    Metabolic

    The catabolism of all three amino acids starts in muscle and yields NADH and FADH2 which can be utilized for ATP generation. … In muscle, the final products of leucine, isoleucine, and valine catabolism can be fully oxidized via the citric acid cycle; in the liver, they can be directed toward the synthesis of ketone bodies (acetoacetate

    Drugs: Pyridoxal phosphate · Biotin · Succinic acid · Glutamic acid · Pyridoxal · Leucine +10 more
  3. Pathway

    Threonine and 2-Oxobutanoate Degradation

    smpdb.ca/view/SMP0000452
    Metabolic

    2-oxobutanoate, also known as 2-Ketobutyric acid, is a 2-keto acid that is commonly produced in the metabolism of amino acids such as methionine and threonine. … While no 2-oxo acid dehydrogenase complex is specific to 2-oxobutanoate, numerous complexes can catalyze its reaction.

    Drugs: Pyridoxal phosphate · Biotin · Threonine · NADH · ATP · Flavin adenine dinucleotide +1 more
  4. Drug

    Hops

    go.drugbank.com/drugs/DB10687
    Approved

    Hops allergenic extract is used in allergenic testing.

    Mixtures: Valerian and Hops Tablets, Sanhelios Valerian Pearls and HopsCategories: Herbs and Natural Products
  5. Drug

    Nimesulide

    go.drugbank.com/drugs/DB04743
    ApprovedWithdrawn

    Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. … Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.

    Categories: Antiinflammatory and Antirheumatic Products, Topical Products for Joint and Muscular PainProducts: NIMESULIDE SUSPENSION 50MG/5ML, UL-FLAM
  6. Drug

    Rivaroxaban

    go.drugbank.com/drugs/DB06228
    ApprovedInvestigational

    However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. … Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary.

    Categories: Blood and Blood Forming Organs, rivaroxaban and acetylsalicylic acidProducts: Eur. 10mg), Rivax 10mg Film Coated Tablets
  7. Drug

    Cefalotin

    go.drugbank.com/drugs/DB00456
    ApprovedVet approvedWithdrawn

    Cefalotin is a cephalosporin antibiotic.

    Products: Keflin Add-vantage Inj 1gm/vial, KEFOLITIN 1 G/10 ML IV/IM ENJEKTABL FLAKON
  8. Drug

    Pancuronium

    go.drugbank.com/drugs/DB01337
    Approved

    As a neuromuscular blocking agent it is more potent than curare but has less effect on the circulatory system and on histamine release. … A bis-quaternary steroid that is a competitive nicotinic antagonist.

    Products: Pavulon Inj 2mg/ml, Pancuronium Bromide - Liq IV 2mg/ml
  9. Drug

    Carvedilol

    go.drugbank.com/drugs/DB01136
    ApprovedInvestigational

    Carvedilol is a racemic mixture where the S(-) enantiomer is both a beta and alpha-1 adrenoceptor blocker, and the R(+) enantiomer is an alpha-1 adrenoceptor blocker. … [L7889,L7892] It is currently used to treat heart failure, left ventricular dysfunction, and hypertension.

    Categories: Compounds used in a research, industrial, or household setting, carvedilol and ivabradineProducts: Dilatrend - Tab 50mg, CARVEDILOL HEXAL 50MG
  10. Drug

    Antihemophilic factor (recombinant), PEGylated

    go.drugbank.com/drugs/DB09329
    ApprovedInvestigational

    PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation in the plasma [L1529]. … Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product _Adynovate_ [FDA label].

    Categories: Amino Acids, Peptides, and Proteins, Compounds used in a research, industrial, or household settingProducts: ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION, ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION