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Tyrosinemia Type 2 (or Richner-Hanhart Syndrome)
smpdb.ca/view/SMP0125603DiseaseTyrosinemia II also known as Richner-Hanhart syndrome is an autosomal recessive disorder caused by a mutation in the TAT gene the encodes for tyrosine aminotransferase. A defect in this enzyme causes excess tyrosine to accumulate in the ...
Drugs: Pyridoxal phosphate · Phenylalanine · Adenosine phosphate · Tyrosine · Glutamic acid · ATP +11 more2-Methyl-3-hydroxybutyryl-CoA Dehydrogenase Deficiency
smpdb.ca/view/SMP0125658Diseasedehydrogenase type-2. … A deficiency in this enzyme results in accumulation of L-lactic acid in blood, spinal fluid, and urine; 2-ethylhydracrylic acid, 2-methyl-3-hydroxybutyric acid, and tiglylglycine in urine.
Enzymes: 3-hydroxyacyl-CoA dehydrogenase type-2, 2-oxoisovalerate dehydrogenase subunit beta, mitochondrialPentostatin
go.drugbank.com/drugs/DB00552ApprovedInvestigationalA potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia.
Categories: Heterocyclic Compounds, 1-Ring, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: CIPROFLOXACINO TABLETAS RECUBIERTAS 500 MG.Ornidazole
go.drugbank.com/drugs/DB13026InvestigationalOrnidazole has been used in trials studying the prevention of Elective Colorectal Surgery.
Mixtures: ORNISASIN 500 MG/500 MG FILM TABLET, 20 ADET, ORCIPOL 500 MG/500 MG FILM TABLET, 28 ADETCategories: Heterocyclic Compounds, 1-RingSiltuximab
go.drugbank.com/drugs/DB09036ApprovedInvestigationalIt is administered as a 1 hour intravenous infusion every 3 weeks. … Siltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high affinity complexes with human interleukin-6 (IL-6).
Categories: Interleukin-6 Antagonist, Cytochrome P-450 CYP3A InducersProducts: SYLVANT 100 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN LİYOFİLİZE TOZ, 1 ADET, SYLVANT 400 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN LİYOFİLİZE TOZ, 1 ADETNystatin
go.drugbank.com/drugs/DB00646ApprovedInvestigationalVet approved[A188562] Nystatin has a greater antifungal activity than amphotericin B - parenterally administered nystatin, however, is associated with significant toxicity and is not available in a formulation appropriate … Nystatin is a polyene antifungal drug that has broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably _Candida_ species.
Mixtures: NİFUNİS 500 MG/200.000 I.U. VAJİNAL OVÜL, 6 ADET, NİFUNİS 500 MG/200.000 I.U. VAJİNAL OVÜL, 12 ADETCategories: Compounds used in a research, industrial, or household settingEthanol
go.drugbank.com/drugs/DB00898ApprovedInvestigationalA clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. … It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
Mixtures: MM Foaming, MM FoamingCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersIcosapent ethyl
go.drugbank.com/drugs/DB08887ApprovedInvestigationalNutraceuticalIt is used as an adjunct therapy for severe hypertriglyceridemia (TG levels > 500 mg/dL) and to reduce the risk of cardiovascular events in certain patients with elevated triglycerides. … FDA approved on July 26, 2012.
Categories: Fatty Acids, Omega-3Synonyms: E-EPA, (all-Z)-5,8,11,14,17-Eicosapentaenoic acid ethyl esterNabilone
go.drugbank.com/drugs/DB00486ApprovedInvestigationalAlthough structurally distinct from THC, nabilone mimics THC's structure and pharmacological activity through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, however … Nabilone is a racemate consisting of the (S,S) and the (R,R) isomers.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsProducts: Canemes 1 mg KapselnAcamprosate
go.drugbank.com/drugs/DB00659ApprovedInvestigationalIt is a structural analogue of the neurotransmitter γ-aminobutyric acid (GABA). … [A229073] Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of alcohol abstinence.
Synonyms: 3-Acetamido-1-propanesulfonic acid, N-AcetylhomotaurineProducts: CAMPRAL 333 MG ENTERIK TABLET, 84 ADET