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Acetaminophen
go.drugbank.com/drugs/DB00316ApprovedInvestigationalAcetaminophen (paracetamol), also commonly known as _Tylenol_, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization … while this drug is taken or prescribed.
Synonyms: N-acetyl-p-aminophenol, 4-acetamidophenolInternational brands: Dapa X-S, St. Joseph Fever ReducerCytosolic non-specific dipeptidase
go.drugbank.com/bio_entities/BE0018303EnzymeHumansN-[(S)-lactoyl]-L-phenylalanine is an exercise-induced metabolite that influences food intake and systemic energy balance (PubMed:25964343). … Upon physiological conditions of amino acids and lactate excess can also catalyze a reverse proteolysis reaction, generating N-[(S)-lactoyl]-L-phenylalanine and possibly other N-lactoyl-amino acids which
Synonyms: HEL-S-13Spermidine and Spermine Biosynthesis
smpdb.ca/view/SMP0000445MetabolicSpermidine is subsequently processed into spermine by spermine synthase in the presence of the aminopropyl donor, S-adenosylmethioninamine. … Spermidine originates from the action of spermidine synthase, which converts the methionine derivative S-adenosylmethionine and the ornithine derivative putrescine into spermidine 5'-methylthioadenosine
Enzymes: S-adenosylmethionine decarboxylase proenzyme, S-adenosylmethionine synthase isoform type-2End Stage Renal Disease (ESRD)
go.drugbank.com/conditions/DBCOND0035540Drugs: Canagliflozin · Dapagliflozin · Empagliflozin · Finerenone · Lanthanum carbonate · Levocarnitine +2 moreEstablished cardiovascular disease
go.drugbank.com/conditions/DBCOND0106958Drugs: Alirocumab · Dapagliflozin · Dulaglutide · Empagliflozin · Icosapent ethyl · Liraglutide +2 more4-aminobutyrate aminotransferase GabT
go.drugbank.com/bio_entities/BE0001510TargetEscherichia coli (strain K12)Pyridoxal phosphate-dependent enzyme that catalyzes transamination between primary amines and alpha-keto acids. Catalyzes the transfer of the amino group from gamma-aminobutyrate (GABA) to alpha-ketoglutarate (KG) to yield succinic semia...
Synonyms: (S)-3-amino-2-methylpropionate transaminaseAlcohol dehydrogenase class-3
go.drugbank.com/bio_entities/BE0000009TargetEnzymeHumansAlso acts as a S-nitroso-glutathione reductase by catalyzing the NADH-dependent reduction of S-nitrosoglutathione, thereby regulating protein S-nitrosylation (By similarity) … Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione (PubMed:8460164).
Synonyms: S-(hydroxymethyl)glutathione dehydrogenaseMyosin regulatory light chain 12A
go.drugbank.com/bio_entities/BE0004293TargetHumansMyosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity)
Synonyms: HEL-S-24Cystathionine beta-Synthase Deficiency
smpdb.ca/view/SMP0000177DiseaseCystathionine Beta-Synthase Deficiency (CBS Deficiency; Homocystinuria) is an autosomal recessive disease caused by a mutation in the CBS gene which codes for cystathionine beta-synthase. A deficiency in this enzyme results in accumulati...
Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 moreEnzymes: S-adenosylmethionine decarboxylase proenzyme, S-methyl-5'-thioadenosine phosphorylaseMethionine Adenosyltransferase Deficiency
smpdb.ca/view/SMP0000221DiseaseMethionine adenosyltransferase (MAT; Hypermethioninemia; MAT I/III deficiency) deficiency is caused by mutations in the MAT1A gene which causes isolated hypermethioninemia. MAT catalyzes the formation of adenosylmethionine from methionin...
Drugs: Pyridoxal phosphate · Tetrahydrofolic acid · Ademetionine · Choline · Adenosine phosphate · Serine +17 moreEnzymes: S-adenosylmethionine decarboxylase proenzyme, S-methyl-5'-thioadenosine phosphorylase