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Displaying results 8851 - 8860 of 10000 in total
  1. Target

    HIV-1 retropepsin

    go.drugbank.com/bio_entities/BE0003339
    TargetHuman immunodeficiency virus 1

    Polypeptides: HIV-1 retropepsin
  2. Target

    KiSS-1 receptor

    go.drugbank.com/bio_entities/BE0003468
    TargetHumans

    Receptor for kisspeptins (kisspeptin-10, kisspeptin-13, kisspeptin-14 and metastin/kisspeptin-54) (PubMed:11457843, PubMed:11527393, PubMed:15020672, PubMed:15596153). The hypothalamic KISS1/KISS1R signaling system plays a central role i...

    Polypeptides: KiSS-1 receptorSynonyms: Hypogonadotropin-1
  3. Target

    Prostaglandin reductase 1

    go.drugbank.com/bio_entities/BE0003795
    TargetEnzymeHumans

    NAD(P)H-dependent oxidoreductase involved in metabolic inactivation of pro- and anti-inflammatory eicosanoids: prostaglandins (PG), leukotrienes (LT) and lipoxins (LX) (PubMed:25619643). Catalyzes with high efficiency the reduction of th...

    Polypeptides: Prostaglandin reductase 1Synonyms: DIG-1, PRG-1
  4. Target

    Peptide deformylase 1

    go.drugbank.com/bio_entities/BE0003874
    TargetBacillus cereus (strain ATCC 14579 / DSM 31)

    Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity ...

    Polypeptides: Peptide deformylase 1Synonyms: PDF 1, Polypeptide deformylase 1
  5. Target

    Iodotyrosine deiodinase 1

    go.drugbank.com/bio_entities/BE0004373
    TargetHumans

    Catalyzes the dehalogenation of halotyrosines such as 3-bromo-L-tyrosine, 3-chloro-L-tyrosine, 3-iodo-L-tyrosine and 3,5-diiodo-L-tyrosine (PubMed:15289438, PubMed:18434651, PubMed:25395621, PubMed:28157283). During thyroid hormone biosy...

    Polypeptides: Iodotyrosine deiodinase 1Synonyms: IYD-1, Iodotyrosine dehalogenase 1
  6. Target

    Urea transporter 1

    go.drugbank.com/bio_entities/BE0004692
    TransporterHumans

    Mediates the transport of urea driven by a concentration gradient across the cell membrane of erythrocytes (PubMed:10514515, PubMed:7797558, PubMed:7989337, PubMed:8997401). Also mediates the transport of urea across the cell membrane of...

    Polypeptides: Urea transporter 1Synonyms: Solute carrier family 14 member 1
  7. Target

    Alpha-actinin-1

    go.drugbank.com/bio_entities/BE0008968
    TargetHumans

    F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. Association with IGSF8 regulates the immune synapse formation and is required for efficient T-cell activation (PubMed:22689882)

    Polypeptides: Alpha-actinin-1Synonyms: Non-muscle alpha-actinin-1
  8. Target

    Trefoil factor 1

    go.drugbank.com/bio_entities/BE0008981
    TargetHumans

    Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine

    Polypeptides: Trefoil factor 1
  9. Target

    Splicing factor 1

    go.drugbank.com/bio_entities/BE0009118
    TargetHumans

    Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor

    Polypeptides: Splicing factor 1
  10. Target

    P2Y purinoceptor 1

    go.drugbank.com/bio_entities/BE0009816
    TargetHumans

    Receptor for extracellular adenine nucleotides such as ADP (PubMed:25822790, PubMed:9038354, PubMed:9442040). In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in...

    Polypeptides: P2Y purinoceptor 1