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Interleukin-1 receptor accessory protein
go.drugbank.com/bio_entities/BE0010488TargetHumansSignaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. … The cellular response is modulated through a non-signaling association with the membrane IL1R2 decoy receptor. Coreceptor for IL1RL1 in the IL-33 signaling system.
Polypeptides: Interleukin-1 receptor accessory proteinSynonyms: Interleukin-1 receptor 3, IL-1 receptor accessory proteinInterleukin-15 receptor subunit alpha
go.drugbank.com/bio_entities/BE0010620TargetHumansHigh-affinity receptor for interleukin-15 (PubMed:8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (By similarity).
Polypeptides: Interleukin-15 receptor subunit alphaSynonyms: IL-15 receptor subunit alphaGDNF family receptor alpha-3
go.drugbank.com/bio_entities/BE0011826TargetHumansARTN-binding leads to autophosphorylation and activation of the RET receptor (PubMed:31535977, PubMed:9883723) … Receptor for artemin (ARTN), a growth factor that supports the survival of sensory and sympathetic peripheral neurons (PubMed:31535977, PubMed:9883723).
Polypeptides: GDNF family receptor alpha-3Synonyms: GDNF receptor alpha-3Vasoactive intestinal polypeptide receptor 2
go.drugbank.com/bio_entities/BE0013151TargetHumansG protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP) (PubMed:7811244, PubMed:35477937, PubMed
Polypeptides: Vasoactive intestinal polypeptide receptor 2Synonyms: VPAC2 receptor, PACAP type III receptorInterleukin-1 receptor-like 1
go.drugbank.com/bio_entities/BE0013861TargetHumansReceptor for interleukin-33 (IL-33) which plays crucial roles in innate and adaptive immunity, contributing to tissue homeostasis and responses to environmental stresses together with coreceptor IL1RAP
Polypeptides: Interleukin-1 receptor-like 1Function: cytokine receptor activityInterleukin-10 receptor subunit beta
go.drugbank.com/bio_entities/BE0014312TargetHumansShared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. … The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity.
Polypeptides: Interleukin-10 receptor subunit betaSynonyms: IL-10 receptor subunit beta, Cytokine receptor class-II member 4TNF receptor-associated factor 6
go.drugbank.com/bio_entities/BE0021309TargetHumansAdapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor (PubMed:12140561, PubMed:19825828, PubMed:8837778).
Polypeptides: TNF receptor-associated factor 6G protein-coupled receptor 6
go.drugbank.com/bio_entities/BE0021832TargetHumansConstitutively active G protein-coupled receptor that maintains high cAMP levels and contributes to several processes including neuronal development, through activation of intracellular signaling pathways
Polypeptides: G protein-coupled receptor 6Synonyms: Sphingosine 1-phosphate receptor GPR6Diethyltoluamide
go.drugbank.com/drugs/DB11282ApprovedDiethyltoluamide (DEET) is the common active ingredient in many insect repellent products. It is widely used to repel biting pests such as mosquitoes and ticks. Every year, DEET formulations are used to protect populations from mosquito-...
International brands: Autan